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Santiago de los Caballeros

$153+ Cheap flights from South Carolina to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STI
Nov 13 — Nov 201
Thu 11/13
Thu 11/20
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago de los Caballeros

Keep the following information in mind while searching for South Carolina to Santiago de los Caballeros flight deals. Data was last updated October 14, 2025.

Round-trip from

$348
(Delta)

One-way from

$153
(Cheapflightsfares)
From South Carolina to Santiago de los Caballeros
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One-way flight from South Carolina to Santiago de los Caballeros
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Find flight deals from South Carolina to Santiago de los Caballeros

Cheapest flights from South Carolina to Santiago de los Caballeros
Explore the most affordable flight options available from South Carolina to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 14, 2025.

This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:00 amCHS - STI
1 stop12h 36mDelta
Mon 11/179:01 pmSTI - CHS
1 stop16h 09mDelta
Deal found 10/12$366
This Priceline deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/142:15 pmCHS - STI
1 stop7h 57mJetBlue
Sun 11/164:41 amSTI - CHS
1 stop9h 38mJetBlue
Deal found 10/12$392
This Expedia deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/12:15 pmCHS - STI
1 stop11h 43mJetBlue
Thu 1/154:55 pmSTI - CHS
2 stops18h 50mJetBlue
Deal found 10/11$432
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amCHS - STI
1 stop12h 32mDelta
Mon 12/86:35 amSTI - CHS
1 stop11h 31mDelta
Deal found 10/12$448
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:00 amCLT - STI
1 stop13h 06mDelta
Sun 11/27:00 amSTI - CLT
1 stop12h 08mDelta
Deal found 10/12$452
This Delta deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/16:00 amCLT - STI
1 stop13h 06mDelta
Sat 11/87:00 amSTI - CLT
1 stop16h 37mDelta
Deal found 10/12$454
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/272:59 pmCHS - STI
2 stops20h 23mMultiple Airlines
Mon 12/11:17 pmSTI - CHS
1 stop9h 48mMultiple Airlines
Deal found 10/12$490
This Kiwi.com deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2410:11 amCHS - STI
1 stop24h 27mMultiple Airlines
Wed 1/146:18 pmSTI - CHS
2 stops22h 04mMultiple Airlines
Deal found 10/12$492
This Mytrip deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:02 amCHS - STI
3 stops26h 20mSpirit Airlines
Mon 11/171:17 pmSTI - CHS
3 stops28h 49mSpirit Airlines
Deal found 10/12$495
This Expedia deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2411:10 amCHS - STI
1 stop13h 24mJetBlue
Wed 1/144:55 pmSTI - CHS
2 stops18h 50mJetBlue
Deal found 10/12$511
This American Airlines deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/266:00 amCHS - STI
1 stop8h 32mAmerican Airlines
Mon 12/16:20 amSTI - CHS
1 stop13h 56mAmerican Airlines
Deal found 10/12$518
This Cheapflightsfares deal was found by Cheapflights users on 10/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/199:49 amCLT - STI
1 stop6h 17mSpirit Airlines
Wed 12/316:18 pmSTI - CLT
1 stop7h 41mSpirit Airlines
Deal found 10/12$709

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Fly from

South Carolina

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 11/14

6:00 am-7:36 pm

1 stop12h 36m

Santiago de los Caballeros

Mon 11/17

9:01 pm-12:10 pm

1 stop16h 09m

$366

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Fri 11/14

2:15 pm-11:12 pm

1 stop7h 57m

Santiago de los Caballeros

Sun 11/16

4:41 am-1:19 pm

1 stop9h 38m

$392

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Wed 1/28

5:45 am-5:06 pm

1 stop10h 21m

Santiago de los Caballeros

Wed 2/4

6:18 pm-12:59 am

1 stop7h 41m

$399

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 1/29

9:49 am-5:06 pm

1 stop6h 17m

Santiago de los Caballeros

Tue 2/17

6:18 pm-9:27 am

1 stop16h 09m

$424

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 11/1

2:15 pm-1:58 am

1 stop11h 43m

Santiago de los Caballeros

Thu 1/15

4:55 pm-10:45 am

2 stops18h 50m

$432

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 12/3

6:00 am-7:32 pm

1 stop12h 32m

Santiago de los Caballeros

Mon 12/8

6:35 am-5:06 pm

1 stop11h 31m

$448

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 1/29

10:00 am-6:46 pm

1 stop7h 46m

Santiago de los Caballeros

Tue 2/17

6:35 am-9:50 pm

2 stops16h 15m

$454

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Sat 1/17

7:25 am-11:54 pm

2 stops15h 29m

Santiago de los Caballeros

Sat 1/24

6:35 am-9:50 pm

2 stops16h 15m

$454

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Fri 10/31

12:56 pm-12:24 am

2 stops11h 28m

Santiago de los Caballeros

Sun 11/2

9:31 pm-9:16 am

1 stop12h 45m

$458

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Sat 11/1

9:39 am-12:24 am

2 stops14h 45m

Santiago de los Caballeros

Sat 11/8

7:00 am-10:37 pm

1 stop16h 37m

$458

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/13

Showing 1-10 of 26 results
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Best time to book a flight from South Carolina to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago de los Caballeros

What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

Currently, November is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $362). Flying from South Carolina to Santiago de los Caballeros in December is currently the most expensive (average of $585). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from South Carolina?

    Located just 6.8 mi from the city center, Santiago de los Caballeros (STI) is the airport most travelers will use when flying to Santiago de los Caballeros from South Carolina.

  • How long is the flight from South Carolina to Santiago de los Caballeros?

    Delta, JetBlue, and Spirit Airlines can get you from South Carolina to Santiago de los Caballeros in just under 7h 57m. Your travel time can differ by up to 4h 39m. Airlines will cover a distance of 1098 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Santiago de los Caballeros?

    The most popular flight routes from South Carolina to Santiago de los Caballeros are Charlotte Douglas - Santiago de los Caballeros, Charleston - Santiago de los Caballeros and Augusta Bush Field - Santiago de los Caballeros.

  • Can I find deals for flights from South Carolina to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago de los Caballeros.

  • Can I find deals for business class flights from South Carolina to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

    Currently, November is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $362). Flying from South Carolina to Santiago de los Caballeros in December is currently the most expensive (average of $585). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Santo Domingo flights
John F Kennedy Intl to Santiago de los Caballeros flights
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Top 2 airlines flying from South Carolina to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from South Carolina to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$371Average$565FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$458Average$715FlexibilityNo cancel feeOn-time71%

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