How long is the flight from South Carolina to Santiago de los Caballeros?

American Airlines, JetBlue, and Spirit Airlines can get you from South Carolina to Santiago de los Caballeros in just under 8h 33m. Your travel time can differ by up to 10h 39m. Airlines will cover a distance of 1261 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What are the most popular routes from South Carolina to Santiago de los Caballeros?

The most popular flight routes from South Carolina to Santiago de los Caballeros are Charlotte Douglas - Santiago de los Caballeros, Charleston - Santiago de los Caballeros and Columbia Metropolitan - Santiago de los Caballeros.

What is the cheapest time of day to fly from SC to STI?

When flying from South Carolina to Santiago de los Caballeros, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What airport do you fly into for flights to Santiago de los Caballeros from South Carolina?

Located just 6.8 mi from the city center, Santiago de los Caballeros (STI) is the airport most travelers will use when flying to Santiago de los Caballeros from South Carolina.

How can I find direct flights from South Carolina to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago de los Caballeros.

Can I find deals for business class flights from South Carolina to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from South Carolina to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$139+ Flights from South Carolina to Santiago de los Caballeros

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from South Carolina to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from South Carolina to Santiago de los Caballeros

Cheapest flights from South Carolina to Santiago de los Caballeros
Explore the most affordable flight options available from South Carolina to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Sun 12/213:43 amSTI - CLT

1 stop11h 29mMultiple Airlines

Deal found 12/3

$429

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Tue 12/233:43 amSTI - CLT

1 stop17h 50mMultiple Airlines

Deal found 12/3

$434

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Sat 12/203:43 amSTI - CLT

1 stop6h 56mMultiple Airlines

Deal found 12/3

$445

Mon 12/1510:34 amCLT - STI

2 stops15h 08mMultiple Airlines

Thu 12/253:43 amSTI - CLT

1 stop17h 50mMultiple Airlines

Deal found 12/3

$472

Sat 12/62:57 pmCLT - STI

1 stop10h 45mSpirit Airlines

Sat 12/131:01 pmSTI - CLT

1 stop11h 58mSpirit Airlines

Deal found 12/3

$476

Mon 12/153:33 pmCHS - STI

2 stops10h 09mMultiple Airlines

Thu 12/253:43 amSTI - CHS

1 stop18h 40mMultiple Airlines

Deal found 12/3

$493

Mon 12/153:33 pmCHS - STI

2 stops10h 09mMultiple Airlines

Sun 12/213:43 amSTI - CHS

1 stop18h 40mMultiple Airlines

Deal found 12/3

$508

Fri 12/1910:18 pmCHS - STI

1 stop27h 24mSpirit Airlines

Thu 12/253:43 amSTI - CHS

1 stop18h 40mSpirit Airlines

Deal found 12/3

$512

Wed 12/176:45 amCHS - STI

1 stop12h 53mJetBlue

Thu 12/2511:25 amSTI - CHS

1 stop7h 41mJetBlue

Deal found 12/3

$524

Mon 12/152:43 pmCHS - STI

1 stop7h 44mJetBlue

Thu 12/2511:25 amSTI - CHS

1 stop7h 41mJetBlue

Deal found 12/3

$527

Mon 12/1510:34 amCLT - STI

2 stops15h 08mSpirit Airlines

Tue 12/233:43 amSTI - CLT

2 stops17h 56mSpirit Airlines

Deal found 12/3

$539

Wed 12/176:45 amCHS - STI

1 stop12h 53mJetBlue

Wed 12/2411:25 amSTI - CHS

1 stop7h 42mJetBlue

Deal found 12/3

$549

Best flights from South Carolina to Santiago de los Caballeros
Discover carefully curated flight deals from South Carolina to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 5, 2025.

Thu 1/157:20 pmCHS - STI

1 stop19h 12mAmerican Airlines

Sun 1/184:33 pmSTI - CHS

2 stops18h 15mAmerican Airlines

Deal found 12/3

$330

Sat 2/1411:47 amCHS - STI

1 stop12h 58mJetBlue

Wed 2/1811:09 pmSTI - CHS

1 stop12h 48mJetBlue

Deal found 12/4

$346

Mon 2/26:00 amCLT - STI

1 stop8h 33mMultiple Airlines

Mon 2/94:40 pmSTI - CLT

2 stops27h 11mMultiple Airlines

Deal found 12/3

$356

Mon 2/26:00 amCLT - STI

1 stop8h 33mSpirit Airlines

Mon 2/94:40 pmSTI - CLT

3 stops25h 14mSpirit Airlines

Deal found 12/3

$388

Thu 1/222:20 pmCLT - STI

1 stop8h 31mUnited Airlines

Tue 2/1012:52 pmSTI - CLT

1 stop9h 24mUnited Airlines

Deal found 12/4

$454

Sat 4/46:00 amCHS - STI

1 stop17h 27mDelta

Tue 4/76:00 amSTI - CHS

2 stops17h 45mDelta

Deal found 12/3

$466

Thu 1/156:35 pmCHS - STI

1 stop19h 58mMultiple Airlines

Mon 1/194:40 pmSTI - CHS

2 stops16h 58mMultiple Airlines

Deal found 12/2

$383

Thu 1/156:10 amCHS - STI

2 stops14h 36mAmerican Airlines

Mon 1/196:00 amSTI - CHS

2 stops18h 07mAmerican Airlines

Deal found 12/2

$430

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Sun 12/213:43 amSTI - CLT

1 stop11h 29mMultiple Airlines

Deal found 12/3

$429

Fri 1/237:59 amCLT - STI

2 stops15h 51mDelta

Tue 2/106:38 amSTI - CLT

1 stop8h 01mDelta

Deal found 12/3

$478

Thu 1/226:30 amCLT - STI

1 stop8h 02mAmerican Airlines

Wed 2/116:00 amSTI - CLT

1 stop16h 02mAmerican Airlines

Deal found 12/3

$454

Fri 12/1910:18 pmCHS - STI

1 stop27h 24mSpirit Airlines

Thu 12/253:43 amSTI - CHS

1 stop18h 40mSpirit Airlines

Deal found 12/3

$512

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Tue 12/233:43 amSTI - CLT

1 stop17h 50mMultiple Airlines

Deal found 12/3

$434

Thu 1/227:59 amCLT - STI

2 stops11h 35mDelta

Tue 2/106:38 amSTI - CLT

2 stops15h 54mDelta

Deal found 12/4

$478

Sat 4/47:02 pmCHS - STI

2 stops17h 13mAmerican Airlines

Tue 4/73:35 pmSTI - CHS

2 stops19h 24mAmerican Airlines

Deal found 12/3

$468

Fri 1/306:20 amGSP - STI

1 stop7h 33mUnited Airlines

Tue 2/34:00 pmSTI - GSP

1 stop8h 48mUnited Airlines

Deal found 12/2

$588

Mon 12/153:33 pmCHS - STI

2 stops10h 09mMultiple Airlines

Sat 12/203:43 amSTI - CHS

1 stop18h 40mMultiple Airlines

Deal found 12/3

$493

Sat 3/76:18 pmCAE - STI

2 stops16h 57mAmerican Airlines

Sat 3/141:15 pmSTI - CAE

2 stops19h 24mAmerican Airlines

Deal found 12/4

$522

Mon 12/153:33 pmCHS - STI

2 stops10h 09mMultiple Airlines

Sun 12/213:43 amSTI - CHS

1 stop18h 40mMultiple Airlines

Deal found 12/3

$493

Sun 4/196:33 pmCAE - STI

2 stops19h 47mAmerican Airlines

Sun 4/263:35 pmSTI - CAE

2 stops18h 17mAmerican Airlines

Deal found 12/3

$527

Last-minute flights from South Carolina to Santiago de los Caballeros
Discover last-minute flight deals from South Carolina to Santiago de los Caballeros. Data last updated December 5, 2025 and is based on user searches.

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Sun 12/213:43 amSTI - CLT

1 stop11h 29mMultiple Airlines

Deal found 12/3

$429

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Tue 12/233:43 amSTI - CLT

1 stop17h 50mMultiple Airlines

Deal found 12/3

$434

Mon 12/158:54 amCLT - STI

1 stop16h 48mMultiple Airlines

Sat 12/203:43 amSTI - CLT

1 stop6h 56mMultiple Airlines

Deal found 12/3

$445

Mon 12/1510:34 amCLT - STI

2 stops15h 08mMultiple Airlines

Thu 12/253:43 amSTI - CLT

1 stop17h 50mMultiple Airlines

Deal found 12/3

$472

Mon 12/153:33 pmCHS - STI

2 stops10h 09mMultiple Airlines

Thu 12/253:43 amSTI - CHS

1 stop18h 40mMultiple Airlines

Deal found 12/3

$493

Mon 12/153:33 pmCHS - STI

2 stops10h 09mMultiple Airlines

Sat 12/203:43 amSTI - CHS

1 stop18h 40mMultiple Airlines

Deal found 12/3

$508

Fri 12/1910:18 pmCHS - STI

1 stop27h 24mSpirit Airlines

Thu 12/253:43 amSTI - CHS

1 stop18h 40mSpirit Airlines

Deal found 12/3

$512

Sat 1/106:00 amCLT - STI

1 stop8h 33mSpirit Airlines

Sat 1/174:40 pmSTI - CLT

1 stop9h 00mSpirit Airlines

Deal found 12/4

$334

Thu 1/156:10 amCHS - STI

2 stops14h 36mAmerican Airlines

Sun 1/184:33 pmSTI - CHS

2 stops18h 15mAmerican Airlines

Deal found 12/3

$323

Thu 1/156:35 pmCHS - STI

1 stop19h 58mMultiple Airlines

Mon 1/194:40 pmSTI - CHS

2 stops16h 58mMultiple Airlines

Deal found 12/2

$383

Thu 1/156:10 amCHS - STI

2 stops14h 36mAmerican Airlines

Mon 1/196:00 amSTI - CHS

2 stops18h 07mAmerican Airlines

Deal found 12/2

$430

Thu 1/222:20 pmCLT - STI

1 stop8h 31mUnited Airlines

Tue 2/1012:52 pmSTI - CLT

1 stop9h 24mUnited Airlines

Deal found 12/4

$454

One-way flights from South Carolina to Santiago de los Caballeros
Search for one-way flight options from South Carolina to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated December 5, 2025.

Sat 1/106:00 amCLT - STI

1 stop8h 33mSpirit Airlines

Deal found 12/4

$139

Sun 1/116:00 amCLT - STI

1 stop8h 33mSpirit Airlines

Deal found 12/4

$142

Mon 1/510:38 pmCLT - STI

1 stop15h 22mFrontier

Deal found 12/2

$152

Wed 12/319:38 pmCLT - STI

1 stop28h 04mSpirit Airlines

Deal found 12/4

$157

Wed 12/312:39 pmCLT - STI

1 stop19h 13mFrontier

Deal found 12/2

$158

Sun 1/49:38 pmCLT - STI

1 stop28h 04mSpirit Airlines

Deal found 12/4

$171

Thu 1/156:01 pmCLT - STI

2 stops20h 32mSpirit Airlines

Deal found 12/4

$175

Mon 12/152:58 pmCLT - STI

1 stop10h 44mSpirit Airlines

Deal found 12/3

$178

Tue 12/309:00 amCLT - STI

1 stop16h 42mSpirit Airlines

Deal found 12/3

$179

Sun 1/118:46 pmCLT - STI

2 stops41h 47mMultiple Airlines

Deal found 12/4

$182

Find flight deals from South Carolina to Santiago de los Caballeros

Round-trip from	$287 (Cheapflightsfares)
One-way from	$139 (Cheapflightsfares)

From South Carolina to Santiago de los Caballeros

Search Deals

One-way flight from South Carolina to Santiago de los Caballeros

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 1/15

7:20 pm-3:32 pm

1 stop19h 12m

Santiago de los Caballeros

Sun 1/18

4:33 pm-9:48 am

2 stops18h 15m

$330

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Sat 2/14

11:47 am-1:45 am

1 stop12h 58m

Santiago de los Caballeros

Wed 2/18

11:09 pm-10:57 am

1 stop12h 48m

$346

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 2/2

6:00 am-3:33 pm

1 stop8h 33m

Santiago de los Caballeros

Mon 2/9

4:40 pm-6:51 pm

2 stops27h 11m

$356

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 1/15

6:35 pm-3:33 pm

1 stop19h 58m

Santiago de los Caballeros

Mon 1/19

4:40 pm-8:38 am

2 stops16h 58m

$383

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 2/2

6:00 am-3:33 pm

1 stop8h 33m

Santiago de los Caballeros

Mon 2/9

4:40 pm-4:54 pm

3 stops25h 14m

$388

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 12/15

8:54 am-2:42 am

1 stop16h 48m

Santiago de los Caballeros

Sun 12/21

3:43 am-2:12 pm

1 stop11h 29m

$429

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 1/15

6:10 am-9:46 pm

2 stops14h 36m

Santiago de los Caballeros

Mon 1/19

6:00 am-11:07 pm

2 stops18h 07m

$430

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 12/15

8:54 am-2:42 am

1 stop16h 48m

Santiago de los Caballeros

Tue 12/23

3:43 am-8:33 pm

1 stop17h 50m

$434

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 1/22

2:20 pm-11:51 pm

1 stop8h 31m

Santiago de los Caballeros

Tue 2/10

12:52 pm-9:16 pm

1 stop9h 24m

$454

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 1/22

6:30 am-3:32 pm

1 stop8h 02m

Santiago de los Caballeros

Wed 2/11

6:00 am-9:02 pm

1 stop16h 02m

$454

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/4

Showing 1-10 of 29 results

Best time to book a flight from South Carolina to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from South Carolina with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago de los Caballeros

What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $344). Flying from South Carolina to Santiago de los Caballeros in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

What airport do you fly into for flights to Santiago de los Caballeros from South Carolina?
Located just 6.8 mi from the city center, Santiago de los Caballeros (STI) is the airport most travelers will use when flying to Santiago de los Caballeros from South Carolina.
How long is the flight from South Carolina to Santiago de los Caballeros?
American Airlines, JetBlue, and Spirit Airlines can get you from South Carolina to Santiago de los Caballeros in just under 8h 33m. Your travel time can differ by up to 10h 39m. Airlines will cover a distance of 1261 mi. This flight may include one or multiple stops.
What are the most popular routes from South Carolina to Santiago de los Caballeros?
The most popular flight routes from South Carolina to Santiago de los Caballeros are Charlotte Douglas - Santiago de los Caballeros, Charleston - Santiago de los Caballeros and Columbia Metropolitan - Santiago de los Caballeros.
Can I find deals for flights from South Carolina to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on South Carolina to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from South Carolina to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago de los Caballeros.
Can I find deals for business class flights from South Carolina to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from South Carolina to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $344). Flying from South Carolina to Santiago de los Caballeros in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 2 airlines flying from South Carolina to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
JetBlue	Cheapest$371	Average$565	FlexibilityNo cancel fee	On-time62%
American Airlines	Cheapest$458	Average$708	FlexibilityNo cancel fee	On-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$139+ Cheap flights from South Carolina to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from South Carolina to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from South Carolina to Santiago de los Caballeros

Cheapest flights from South Carolina to Santiago de los CaballerosExplore the most affordable flight options available from South Carolina to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.

Explore the most affordable flight options available from South Carolina to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.

Find flight deals from South Carolina to Santiago de los Caballeros

Keep the following information in mind while searching for South Carolina to Santiago de los Caballeros flight deals. Data was last updated December 5, 2025.

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Best time to book a flight from South Carolina to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from South Carolina with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago de los Caballeros

What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago de los Caballeros from South Carolina?

How long is the flight from South Carolina to Santiago de los Caballeros?

What are the most popular routes from South Carolina to Santiago de los Caballeros?

Can I find deals for flights from South Carolina to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from South Carolina to Santiago de los Caballeros?

Can I find deals for business class flights from South Carolina to Santiago de los Caballeros?

What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Santiago de los Caballeros

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from South Carolina to Santiago de los Caballeros
Explore the most affordable flight options available from South Carolina to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 5, 2025.