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Santiago de los Caballeros

$118+ Cheap flights from South Carolina to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/1. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STI
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from South Carolina to Santiago de los Caballeros

Keep the following information in mind while searching for South Carolina to Santiago de los Caballeros flight deals. Data was last updated January 15, 2026.

Round-trip from

$260
(Mytrip)

One-way from

$118
(Priceline)
From South Carolina to Santiago de los Caballeros
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One-way flight from South Carolina to Santiago de los Caballeros
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Find flight deals from South Carolina to Santiago de los Caballeros

Cheapest flights from South Carolina to Santiago de los Caballeros
Explore the most affordable flight options available from South Carolina to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Mytrip deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/16:00 am
CLT
-
STI
1 stop8h 33m
Spirit Airlines
Tue 2/104:40 pm
STI
-
CLT
1 stop9h 00m
Spirit Airlines
Deal found 1/14$260
This Cheapflightsfares deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/246:00 am
CLT
-
STI
1 stop8h 33m
Spirit Airlines
Mon 2/24:40 pm
STI
-
CLT
1 stop9h 00m
Spirit Airlines
Deal found 1/14$268
This Cheapflightsfares deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/36:00 am
CLT
-
STI
1 stop8h 33m
Spirit Airlines
Fri 2/134:40 pm
STI
-
CLT
1 stop8h 16m
Spirit Airlines
Deal found 1/15$293
This Cheapflightsfares deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/225:55 am
CLT
-
STI
1 stop8h 40m
Spirit Airlines
Tue 2/244:40 pm
STI
-
CLT
1 stop8h 16m
Spirit Airlines
Deal found 1/13$296
This Travelocity deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/76:00 am
CLT
-
STI
1 stop8h 33m
Spirit Airlines
Sat 2/214:40 pm
STI
-
CLT
1 stop8h 16m
Spirit Airlines
Deal found 1/14$297
This Cheapflightsfares deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/215:55 am
CLT
-
STI
1 stop8h 40m
Spirit Airlines
Mon 3/24:40 pm
STI
-
CLT
1 stop8h 16m
Spirit Airlines
Deal found 1/14$326
This FlightHub deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 am
CLT
-
STI
1 stop8h 35m
Spirit Airlines
Mon 4/203:40 pm
STI
-
CLT
1 stop9h 00m
Spirit Airlines
Deal found 1/15$327
This FlightHub deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/258:07 am
CHS
-
STI
1 stop6h 28m
Spirit Airlines
Mon 3/303:43 pm
STI
-
CHS
1 stop6h 50m
Spirit Airlines
Deal found 1/14$328
This Delta deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/2912:00 pm
CHS
-
STI
1 stop11h 50m
Delta
Mon 2/26:39 am
STI
-
CHS
1 stop11h 32m
Delta
Deal found 1/15$333
This Cheapflightsfares deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/266:00 am
CLT
-
STI
1 stop8h 33m
Spirit Airlines
Fri 2/64:40 pm
STI
-
CLT
1 stop9h 00m
Spirit Airlines
Deal found 1/15$336
This Cheapflightsfares deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/131:24 pm
CLT
-
STI
1 stop12h 25m
Spirit Airlines
Sun 3/153:40 pm
STI
-
CLT
1 stop8h 58m
Spirit Airlines
Deal found 1/13$346
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:45 pm
CHS
-
STI
2 stops17h 45m
American Airlines
Mon 3/307:00 am
STI
-
CHS
1 stop27h 26m
American Airlines
Deal found 1/14$347

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Fly from

South Carolina

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Sun 2/22

5:55 am-3:35 pm

1 stop8h 40m

Santiago de los Caballeros

Tue 2/24

4:40 pm-11:56 pm

1 stop8h 16m

$296

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 3/25

8:07 am-2:35 pm

1 stop6h 28m

Santiago de los Caballeros

Mon 3/30

3:43 pm-10:33 pm

1 stop6h 50m

$328

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Thu 1/29

12:00 pm-12:50 am

1 stop11h 50m

Santiago de los Caballeros

Mon 2/2

6:39 am-5:11 pm

1 stop11h 32m

$333

CharlestonSantiago de los Caballeros

CHS - STI

CHSSTI

Charleston

Wed 3/25

6:45 pm-12:30 pm

2 stops17h 45m

Santiago de los Caballeros

Mon 3/30

7:00 am-10:26 am

1 stop27h 26m

$347

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 2/2

6:00 am-3:33 pm

1 stop8h 33m

Santiago de los Caballeros

Wed 2/11

4:40 pm-12:06 pm

1 stop20h 26m

$356

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Sun 2/1

6:00 am-3:33 pm

1 stop8h 33m

Santiago de los Caballeros

Sun 2/8

4:40 pm-8:11 am

1 stop16h 31m

$360

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Wed 2/4

6:00 am-3:33 pm

1 stop8h 33m

Santiago de los Caballeros

Tue 2/10

4:40 pm-4:54 pm

2 stops25h 14m

$365

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Sat 2/21

5:55 am-3:35 pm

1 stop8h 40m

Santiago de los Caballeros

Tue 2/24

4:40 pm-11:56 pm

1 stop8h 16m

$370

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Wed 2/4

6:00 am-3:33 pm

1 stop8h 33m

Santiago de los Caballeros

Sat 2/7

4:40 pm-12:40 am

1 stop9h 00m

$373

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 2/16

10:42 pm-3:35 pm

2 stops15h 53m

Santiago de los Caballeros

Tue 2/24

4:40 pm-8:26 am

1 stop16h 46m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/14

Showing 1-10 of 38 results
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Best time to book a flight from South Carolina to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago de los Caballeros

What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $321). Flying from South Carolina to Santiago de los Caballeros in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from South Carolina?

    Located just 6.8 mi from the city center, Santiago de los Caballeros (STI) is the airport most travelers will use when flying to Santiago de los Caballeros from South Carolina.

  • How long is the flight from South Carolina to Santiago de los Caballeros?

    Spirit Airlines, Delta, and American Airlines can get you from South Carolina to Santiago de los Caballeros in just under 8h 40m. Your travel time can differ by up to 7h 40m. Airlines will cover a distance of 1261 mi. This flight may include one or multiple stops.

  • What are the most popular routes from South Carolina to Santiago de los Caballeros?

    The most popular flight routes from South Carolina to Santiago de los Caballeros are Charlotte Douglas - Santiago de los Caballeros, Charleston - Santiago de los Caballeros and Columbia Metropolitan - Santiago de los Caballeros.

  • Can I find deals for flights from South Carolina to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago de los Caballeros.

  • Can I find deals for business class flights from South Carolina to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $321). Flying from South Carolina to Santiago de los Caballeros in June is currently the most expensive (average of $528). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for South Carolina to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
Newark to Punta Cana flights
John F Kennedy Intl to Punta Cana flights
John F Kennedy Intl to Santo Domingo flights
Newark to Santiago de los Caballeros flights
John F Kennedy Intl to Santiago de los Caballeros flights
Newark to Santo Domingo flights
LaGuardia to Punta Cana flights
O'Hare Intl to Punta Cana flights
Orlando to Punta Cana flights
Dulles Intl to Punta Cana flights
LaGuardia to Santo Domingo flights
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LaGuardia to Santiago de los Caballeros flights
Fort Lauderdale to Punta Cana flights
Atlanta to Punta Cana flights
Miami to Punta Cana flights
Fort Lauderdale to Santo Domingo flights
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Midway to Punta Cana flights
Boston to Santo Domingo flights
Miami to Santo Domingo flights
Philadelphia to Punta Cana flights
Detroit to Punta Cana flights
John F Kennedy Intl to Puerto Plata flights
Reagan-National to Punta Cana flights
Orlando to Santo Domingo flights
Charlotte to Punta Cana flights
Dallas/Fort Worth to Punta Cana flights
Boston to Santiago de los Caballeros flights
Hobby to Punta Cana flights
Newark to Puerto Plata flights
Minneapolis to Punta Cana flights
Atlanta to Santo Domingo flights
Tampa to Punta Cana flights
Denver to Punta Cana flights
George Bush Intcntl to Punta Cana flights
Orlando to Santiago de los Caballeros flights
Atlantic City to Punta Cana flights
Los Angeles to Punta Cana flights
Cleveland to Punta Cana flights
Cincinnati to Punta Cana flights
Pittsburgh to Punta Cana flights
Dulles Intl to Santo Domingo flights
LaGuardia to Puerto Plata flights
Nashville to Punta Cana flights
Salt Lake City to Santiago de los Caballeros flights
Indianapolis to Punta Cana flights
Raleigh to Punta Cana flights
Seattle to Punta Cana flights
Baltimore to Santo Domingo flights

Top 2 airlines flying from South Carolina to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from South Carolina to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$371Average$565FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$458Average$708FlexibilityNo cancel feeOn-time71%

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