Santiago de los Caballeros

$155+ Cheap flights from South Carolina to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/20. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — STI
Aug 21 — Aug 281
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Cheap flight deals from South Carolina to Santiago de los Caballeros

Keep the following information in mind while searching for South Carolina to Santiago de los Caballeros flight deals. Data was last updated August 16, 2025.

Round-trip from

$323
(FlightHub)

One-way from

$155
(FlightHub)
From South Carolina to Santiago de los Caballeros
One-way flight from South Carolina to Santiago de los Caballeros

Find flight deals from South Carolina to Santiago de los Caballeros

Cheapest flights from South Carolina to Santiago de los Caballeros
Explore the most affordable flight options available from South Carolina to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 16, 2025.

This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/95:45 amCLT - STI
1 stop5h 18mSpirit Airlines
Wed 9/1012:10 pmSTI - CLT
1 stop10h 49mSpirit Airlines
Deal found 8/14$323
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:45 amCLT - STI
1 stop5h 18mSpirit Airlines
Thu 10/912:13 pmSTI - CLT
1 stop8h 47mSpirit Airlines
Deal found 8/14$331
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/265:45 amCLT - STI
1 stop5h 18mSpirit Airlines
Mon 9/2912:10 pmSTI - CLT
1 stop10h 49mSpirit Airlines
Deal found 8/14$332
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:45 amCLT - STI
1 stop5h 18mSpirit Airlines
Sat 9/612:10 pmSTI - CLT
1 stop10h 49mSpirit Airlines
Deal found 8/14$340
This Cheapflightsfares deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/176:15 amCLT - STI
1 stop4h 53mSpirit Airlines
Mon 10/2012:13 pmSTI - CLT
1 stop8h 47mSpirit Airlines
Deal found 8/14$347
This Cheapflightsfares deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/149:52 pmCLT - STI
1 stop13h 11mSpirit Airlines
Sun 9/2112:10 pmSTI - CLT
1 stop10h 49mSpirit Airlines
Deal found 8/15$348
This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:15 amCLT - STI
1 stop4h 53mSpirit Airlines
Tue 10/1412:13 pmSTI - CLT
2 stops19h 34mSpirit Airlines
Deal found 8/14$358
This FlightHub deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/55:45 amCLT - STI
1 stop5h 18mSpirit Airlines
Sun 9/712:10 pmSTI - CLT
1 stop21h 12mSpirit Airlines
Deal found 8/14$365
This SmartFares deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/236:15 amCLT - STI
1 stop4h 53mSpirit Airlines
Wed 10/2912:13 pmSTI - CLT
2 stops25h 16mSpirit Airlines
Deal found 8/13$384
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/166:00 amCHS - STI
1 stop6h 40mDelta
Fri 9/268:40 pmSTI - CHS
1 stop15h 27mDelta
Deal found 8/14$429
This American Airlines deal was found by Cheapflights users on 8/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1810:56 amCHS - STI
1 stop9h 52mAmerican Airlines
Fri 8/221:31 pmSTI - CHS
1 stop10h 52mAmerican Airlines
Deal found 8/15$459
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/147:50 pmCHS - STI
1 stop24h 58mAmerican Airlines
Wed 8/201:31 pmSTI - CHS
2 stops18h 45mAmerican Airlines
Deal found 8/14$473

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
Use the filters below to find and compare flights from South Carolina to Santiago de los Caballeros that are best for you.

Fly from

South Carolina

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 10/16

6:15 am-11:08 am

1 stop4h 53m

Santiago de los Caballeros

Mon 10/20

12:13 pm-9:59 pm

1 stop9h 46m

$323

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Tue 10/7

6:15 am-11:08 am

1 stop4h 53m

Santiago de los Caballeros

Tue 10/14

12:13 pm-9:59 pm

1 stop9h 46m

$323

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Tue 9/9

5:45 am-11:03 am

1 stop5h 18m

Santiago de los Caballeros

Wed 9/10

12:10 pm-10:59 pm

1 stop10h 49m

$323

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Wed 10/22

6:15 am-11:08 am

1 stop4h 53m

Santiago de los Caballeros

Wed 10/29

12:13 pm-11:37 pm

1 stop11h 24m

$331

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Mon 9/22

5:45 am-11:03 am

1 stop5h 18m

Santiago de los Caballeros

Thu 10/9

12:13 pm-9:00 pm

1 stop8h 47m

$331

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Thu 10/23

6:15 am-11:08 am

1 stop4h 53m

Santiago de los Caballeros

Wed 10/29

12:13 pm-11:37 pm

1 stop11h 24m

$331

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Fri 9/26

5:45 am-11:03 am

1 stop5h 18m

Santiago de los Caballeros

Mon 9/29

12:10 pm-10:59 pm

1 stop10h 49m

$332

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Fri 9/5

5:45 am-11:03 am

1 stop5h 18m

Santiago de los Caballeros

Sat 9/6

12:10 pm-10:59 pm

1 stop10h 49m

$340

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Fri 10/17

6:15 am-11:08 am

1 stop4h 53m

Santiago de los Caballeros

Mon 10/20

12:13 pm-9:00 pm

1 stop8h 47m

$347

CharlotteSantiago de los Caballeros

CLT - STI

CLTSTI

Charlotte Douglas

Sun 9/14

9:52 pm-11:03 am

1 stop13h 11m

Santiago de los Caballeros

Sun 9/21

12:10 pm-10:59 pm

1 stop10h 49m

$348

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 26 results
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Best time to book a flight from South Carolina to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Santiago de los Caballeros

What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $347). Flying from South Carolina to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Santiago de los Caballeros from South Carolina?

    Located just 6.8 mi from the city center, Santiago de los Caballeros (STI) is the airport most travelers will use when flying to Santiago de los Caballeros from South Carolina.

  • What are the cheapest airlines to fly from South Carolina to Santiago de los Caballeros one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $155. Users have also found prices from $256 and $261 on Delta and American Airlines, respectively.

  • What are the most popular routes from South Carolina to Santiago de los Caballeros?

  • Can I find deals for flights from South Carolina to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on South Carolina to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Santiago de los Caballeros.

  • Can I find deals for business class flights from South Carolina to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from South Carolina to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Santiago de los Caballeros (average of $347). Flying from South Carolina to Santiago de los Caballeros in July is currently the most expensive (average of $601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 2 airlines flying from South Carolina to Santiago de los Caballeros

Discover the top 2 airlines that operate flights from South Carolina to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$371Average$565FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$500Average$708FlexibilityNo cancel feeOn-time71%

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