What are the cheapest airlines to fly from Irvine to Santiago de los Caballeros one-way?

To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $173. Delta flights start at $235 while deals on American Airlines start at $240 one-way.

What is the cheapest day to fly from Irvine to Santiago de los Caballeros?

Travelers seeking maximum savings on their Irvine to Santiago de los Caballeros flight should consider departing on Wednesday evenings when fares are most often at their lowest. Sunday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What are the most popular airlines that fly from Irvine to Santiago de los Caballeros?

Consider American Airlines, JetBlue or Copa Airlines when booking your flight. These represent the most popular airlines when flying from Irvine to Santiago de los Caballeros.

What is the cheapest month to fly from Irvine to Santiago de los Caballeros?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, October can be a great choice for travel to Santiago de los Caballeros. Flights to Santiago de los Caballeros from Irvine in October are about $630 on average during October, but can be found for as low as $381.

What airport do you fly into for flights to Santiago de los Caballeros from Irvine?

Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Irvine. On average, Santiago has 0 inbound flights from Irvine per day from 4 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.

How can I find direct flights from Irvine to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santiago de los Caballeros.

Can I find deals for business class flights from Irvine to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Irvine to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$192+ Flights from Irvine to Santiago de los Caballeros

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Cheap flight deals from Irvine to Santiago de los Caballeros

Round-trip from	$335 (SmartFares)
One-way from	$173 (SmartFares)
Popular in	December
Cheapest in	October
Average price	$905

From Irvine to Santiago de los Caballeros

Search Deals

One-way flight from Irvine to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 20% potential increase in price ($164 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($46 potential savings vs. average RT price).

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Average for round-trip flights in July 2025

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Find flight deals from Irvine to Santiago de los Caballeros

Cheapest flights from Irvine to Santiago de los Caballeros
Explore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Tue 9/1612:22 pmLAX - STI

2 stops19h 41mSpirit Airlines

Fri 9/2612:10 pmSTI - LAX

2 stops23h 38mSpirit Airlines

Deal found 7/30

$377

Fri 9/192:21 pmLAX - STI

2 stops17h 44mMultiple Airlines

Mon 9/2912:10 pmSTI - LAX

1 stop12h 46mMultiple Airlines

Deal found 7/29

$448

Wed 9/1010:20 pmLAX - STI

1 stop11h 20mDelta

Fri 9/198:40 pmSTI - LAX

1 stop16h 35mDelta

Deal found 7/31

$493

Tue 9/97:40 pmLAX - STI

2 stops13h 47mAmerican Airlines

Thu 9/181:29 pmSTI - LAX

1 stop12h 14mAmerican Airlines

Deal found 7/31

$497

Tue 9/1611:59 pmLAX - STI

1 stop14h 56mJetBlue

Thu 9/253:20 amSTI - LAX

1 stop20h 38mJetBlue

Deal found 7/31

$553

Best flights from Irvine to Santiago de los Caballeros
Discover carefully curated flight deals from Irvine to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 31, 2025.

Tue 9/1612:22 pmLAX - STI

2 stops19h 41mSpirit Airlines

Fri 9/2612:10 pmSTI - LAX

2 stops23h 38mSpirit Airlines

Deal found 7/30

$377

Fri 9/192:21 pmLAX - STI

2 stops17h 44mMultiple Airlines

Mon 9/2912:10 pmSTI - LAX

1 stop12h 46mMultiple Airlines

Deal found 7/29

$448

Wed 9/1010:20 pmLAX - STI

1 stop11h 20mDelta

Fri 9/198:40 pmSTI - LAX

1 stop16h 35mDelta

Deal found 7/31

$493

Tue 9/97:40 pmLAX - STI

2 stops13h 47mAmerican Airlines

Thu 9/181:29 pmSTI - LAX

1 stop12h 14mAmerican Airlines

Deal found 7/31

$497

Wed 10/154:30 pmLAX - STI

1 stop16h 03mJetBlue

Fri 10/243:20 amSTI - LAX

1 stop23h 51mJetBlue

Deal found 7/29

$555

Last-minute flights from Irvine to Santiago de los Caballeros
Discover last-minute flight deals from Irvine to Santiago de los Caballeros. Data last updated July 31, 2025 and is based on user searches.

Tue 8/51:57 pmLAX - STI

2 stops19h 54mMultiple Airlines

Fri 8/1510:20 amSTI - LAX

1 stop15h 09mMultiple Airlines

Deal found 7/30

$527

Tue 8/510:45 pmLAX - STI

1 stop19h 03mAmerican Airlines

Fri 8/157:00 amSTI - LAX

1 stop13h 59mAmerican Airlines

Deal found 7/31

$635

Tue 8/59:30 amLAX - STI

1 stop12h 22mJetBlue

Fri 8/82:17 amSTI - LAX

1 stop15h 53mJetBlue

Deal found 7/29

$785

Sat 8/911:20 amLAX - STI

2 stops19h 30mSpirit Airlines

Mon 8/1810:20 amSTI - LAX

2 stops16h 38mSpirit Airlines

Deal found 7/29

$552

Sat 8/99:30 pmLAX - STI

1 stop12h 13mDelta

Thu 8/212:42 pmSTI - LAX

1 stop13h 06mDelta

Deal found 7/31

$2,572

Sun 8/177:58 pmLAX - STI

2 stops10h 17mSpirit Airlines

Thu 8/2810:20 amSTI - LAX

2 stops15h 21mSpirit Airlines

Deal found 7/31

$437

Sun 8/177:50 amLAX - STI

1 stop9h 58mAmerican Airlines

Thu 8/287:00 amSTI - LAX

1 stop17h 22mAmerican Airlines

Deal found 7/31

$544

One-way flights from Irvine to Santiago de los Caballeros
Search for one-way flight options from Irvine to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated July 31, 2025.

Thu 8/2110:10 amLAX - STI

2 stops20h 05mSpirit Airlines

Deal found 7/29

$192

Sun 9/76:00 amLAX - STI

1 stop15h 47mDelta

Deal found 7/31

$235

Thu 8/217:50 amLAX - STI

1 stop9h 58mAmerican Airlines

Deal found 7/29

$240

Sun 9/78:00 amLAX - STI

3 stops26h 00mMultiple Airlines

Deal found 7/30

$2,146

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 9/16

12:22 pm-11:03 am

2 stops19h 41m

Santiago de los Caballeros

Fri 9/26

12:10 pm-8:48 am

2 stops23h 38m

$377

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Fri 9/19

2:21 pm-11:05 am

2 stops17h 44m

Santiago de los Caballeros

Mon 9/29

12:10 pm-9:56 pm

1 stop12h 46m

$448

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Wed 9/10

10:20 pm-12:40 pm

1 stop11h 20m

Santiago de los Caballeros

Fri 9/19

8:40 pm-10:15 am

1 stop16h 35m

$493

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 9/9

7:40 pm-12:27 pm

2 stops13h 47m

Santiago de los Caballeros

Thu 9/18

1:29 pm-10:43 pm

1 stop12h 14m

$497

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Wed 10/15

4:30 pm-11:33 am

1 stop16h 03m

Santiago de los Caballeros

Fri 10/24

3:20 am-12:11 am

1 stop23h 51m

$555

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Thu 8/21

10:10 am-9:15 am

2 stops20h 05m

$192

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sun 9/7

6:00 am-12:47 am

1 stop15h 47m

$235

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Thu 8/21

7:50 am-8:48 pm

1 stop9h 58m

$240

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sun 9/7

8:00 am-1:00 pm

3 stops26h 00m

$2,146

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Irvine to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Irvine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santiago de los Caballeros

What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Irvine to Santiago de los Caballeros (average of $347). Flying from Irvine to Santiago de los Caballeros in July is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to STI?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Santiago de los Caballeros as you normally would.

Reviews of airlines servicing Santiago de los Caballeros

Read through reviews of airlines operating flights from Irvine to Santiago de los Caballeros, such as Delta, JetBlue, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,981 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

JetBlue

7.3

Good

2,914 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Spirit Airlines

6.3

Okay

8,049 reviews

Delta

8.0

Very good

7,981 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What airport do you fly into for flights to Santiago de los Caballeros from Irvine?
Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Irvine. On average, Santiago has 0 inbound flights from Irvine per day from 4 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.
What are the cheapest airlines to fly from Irvine to Santiago de los Caballeros one-way?
To fly one-way, consider booking your trip with Spirit Airlines, which is currently one of the cheapest options available, starting at $173. Delta flights start at $235 while deals on American Airlines start at $240 one-way.
Can I find deals for flights from Irvine to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Irvine to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Irvine to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santiago de los Caballeros.
Can I find deals for business class flights from Irvine to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Irvine to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Irvine to Santiago de los Caballeros (average of $347). Flying from Irvine to Santiago de los Caballeros in July is currently the most expensive (average of $603). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Irvine to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$381	Average$427	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$423	Average$689	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$425	Average$674	FlexibilityNo cancel fee	On-time71%
JetBlue	Cheapest$446	Average$558	FlexibilityNo cancel fee	On-time62%

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$192+ Cheap flights from Irvine, CA to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Irvine to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Irvine to Santiago de los Caballeros

Keep the following information in mind while searching for Irvine to Santiago de los Caballeros flight deals. Data was last updated July 31, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Irvine to Santiago de los Caballeros

Cheapest flights from Irvine to Santiago de los CaballerosExplore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Explore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Irvine to Santiago de los Caballeros that are best for you.

Best time to book a flight from Irvine to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Irvine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santiago de los Caballeros

What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

What is the cheapest time of day to fly from IR9 to STI?

Find hourly flight availability from Irvine to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

Reviews of airlines servicing Santiago de los Caballeros

Read through reviews of airlines operating flights from Irvine to Santiago de los Caballeros, such as Delta, JetBlue, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Santiago de los Caballeros from Irvine?

What are the cheapest airlines to fly from Irvine to Santiago de los Caballeros one-way?

Can I find deals for flights from Irvine to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Irvine to Santiago de los Caballeros?

Can I find deals for business class flights from Irvine to Santiago de los Caballeros?

What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Irvine to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Irvine to Santiago de los Caballeros

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Cheapest flights from Irvine to Santiago de los Caballeros
Explore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.