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Santiago de los Caballeros

$449+ Cheap flights from Irvine, CA to Santiago de los Caballeros (STI)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — STI
Oct 16 — Oct 231
Thu 10/16
Thu 10/23
1 adult, Economy
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Cheap flight deals from Irvine to Santiago de los Caballeros

Keep the following information in mind while searching for Irvine to Santiago de los Caballeros flight deals. Data was last updated September 16, 2025.

Round-trip from

$447
(Expedia)

Popular in

December

Cheapest in

October

Average price

$594
From Irvine to Santiago de los Caballeros
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($195 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($46 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Irvine to Santiago de los Caballeros

Cheapest flights from Irvine to Santiago de los Caballeros
Explore the most affordable flight options available from Irvine to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/129:05 pmLAX - STI
1 stop12h 08mAmerican Airlines
Wed 10/291:14 pmSTI - LAX
1 stop14h 04mAmerican Airlines
Deal found 9/14$449
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/511:15 amLAX - STI
1 stop20h 23mMultiple Airlines
Mon 10/1311:43 amSTI - LAX
2 stops47h 45mMultiple Airlines
Deal found 9/16$454
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1710:26 pmLAX - STI
2 stops13h 07mAmerican Airlines
Thu 11/274:35 pmSTI - LAX
2 stops17h 03mAmerican Airlines
Deal found 9/14$456
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/711:27 pmLAX - STI
1 stop9h 46mAmerican Airlines
Mon 10/131:14 pmSTI - LAX
1 stop23h 22mAmerican Airlines
Deal found 9/14$461
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/72:27 pmLAX - STI
2 stops41h 11mMultiple Airlines
Mon 10/1311:43 amSTI - LAX
1 stop14h 12mMultiple Airlines
Deal found 9/14$465
This Mytrip deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:53 pmLAX - STI
3 stops32h 45mSpirit Airlines
Sun 10/1211:43 amSTI - LAX
3 stops30h 37mSpirit Airlines
Deal found 9/15$502
This Mytrip deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/710:53 pmLAX - STI
3 stops32h 45mSpirit Airlines
Mon 10/1311:43 amSTI - LAX
3 stops23h 34mSpirit Airlines
Deal found 9/14$503

Cheapflights Fare Finder

 
Customize your flight search to find flights from Irvine to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Irvine to Santiago de los Caballeros that are best for you.

Fly from

Irvine

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sun 10/5

11:15 am-10:38 am

1 stop20h 23m

Santiago de los Caballeros

Mon 10/13

11:43 am-8:28 am

2 stops47h 45m

$454

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 10/7

11:27 pm-12:13 pm

1 stop9h 46m

Santiago de los Caballeros

Mon 10/13

1:14 pm-9:36 am

1 stop23h 22m

$461

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Mon 11/17

9:31 pm-3:33 pm

1 stop14h 02m

Santiago de los Caballeros

Thu 11/27

4:35 pm-9:04 am

1 stop20h 29m

$464

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 10/7

2:27 pm-10:38 am

2 stops41h 11m

Santiago de los Caballeros

Mon 10/13

11:43 am-10:55 pm

1 stop14h 12m

$465

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 10/7

10:53 pm-10:38 am

3 stops32h 45m

Santiago de los Caballeros

Mon 10/13

11:43 am-8:17 am

3 stops23h 34m

$503

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 10/7

10:53 pm-10:38 am

3 stops32h 45m

Santiago de los Caballeros

Sun 10/12

11:43 am-8:17 am

2 stops23h 34m

$503

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Tue 11/18

7:40 am-12:59 am

1 stop13h 19m

Santiago de los Caballeros

Thu 11/27

6:35 am-3:11 pm

1 stop12h 36m

$524

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sat 12/27

11:59 pm-5:06 pm

2 stops37h 07m

$470

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sat 12/27

10:45 pm-5:06 pm

3 stops38h 21m

$507

Los AngelesSantiago de los Caballeros

LAX - STI

LAXSTI

Los Angeles

Sat 12/27

6:00 am-9:03 pm

1 stop11h 03m

$690

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Best time to book a flight from Irvine to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Irvine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Santiago de los Caballeros

What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Irvine to Santiago de los Caballeros (average of $347). Flying from Irvine to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to STI?

Find hourly flight availability from Irvine to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Irvine to Santiago de los Caballeros as you normally would.

Reviews of airlines servicing Santiago de los Caballeros

Get insights into the airlines that provide service to Santiago de los Caballeros. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago de los Caballeros. Reviews last updated September 16, 2025.
Read through reviews of airlines operating flights from Irvine to Santiago de los Caballeros, such as Delta, Copa Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,957 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,531 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,924 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
JetBlue
7.2
Good
2,914 reviews
Delta
8.0
Very good
7,957 reviews

Comfort

7.9

Food

7.3

Crew

8.5

Entertainment

7.9

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Santiago de los Caballeros from Irvine?

    Most people fly into Santiago de los Caballeros (STI) if they book a flight to Santiago de los Caballeros from Irvine. On average, Santiago has 0 inbound flights from Irvine per day from 5 airlines. Santiago de los Caballeros is conveniently located just 6.8 mi from Santiago de los Caballeros’s city center.

  • How long is the flight from Irvine to Santiago de los Caballeros?

    Departing from Irvine to Santiago de los Caballeros will take you 9h 46m. Airlines will cover a distance of 3085 mi.

  • Can I find deals for flights from Irvine to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Irvine to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Santiago de los Caballeros.

  • Can I find deals for business class flights from Irvine to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Irvine to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Irvine to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Irvine to Santiago de los Caballeros (average of $347). Flying from Irvine to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Irvine to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Irvine to Santiago de los Caballeros

Discover the top 5 airlines that operate flights from Irvine to Santiago de los Caballeros. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$391Average$427FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$425Average$675FlexibilityNo cancel feeOn-time71%
DeltaCheapest$442Average$594FlexibilityNo cancel feeOn-timeN/A
JetBlueCheapest$482Average$618FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$492Average$654FlexibilityNo cancel feeOn-time69%

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