What are the cheapest airlines to fly from Indianapolis to Santiago de los Caballeros one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $267. However, be on the lookout for offers from American Airlines and Spirit Airlines, as they are both options that can get you from Indianapolis to Santiago de los Caballeros for a low price.

What is the cheapest day to fly from Indianapolis to Santiago de los Caballeros?

Travelers seeking maximum savings on their Indianapolis to Santiago de los Caballeros flight should consider departing on Wednesday mornings when fares are most often at their lowest. Tuesday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Indianapolis to Santiago de los Caballeros?

The most popular airlines flying from Indianapolis to Santiago de los Caballeros are American Airlines, Delta and United Airlines. Something to consider prior to booking your flight.

What is the cheapest day to fly round-trip from Indianapolis to Santiago de los Caballeros?

Departing on a Tuesday is a good option for securing a great price. You can expect to save up to 41% when planning your travel around this day of the week.

What is the cheapest month to fly from Indianapolis to Santiago de los Caballeros?

Due to multiple factors, expect to potentially pay more when booking in December. For low rates, September can be a great choice for travel to Santiago de los Caballeros. Flights to Santiago de los Caballeros from Indianapolis in September are about $683 on average during September, but can be found for as low as $313.

Most accurate provider : When it comes to deals on Indianapolis-Santiago de los Caballeros flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Indianapolis-Santiago de los Caballeros flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Indianapolis-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Indianapolis-Santiago de los Caballeros flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from Indianapolis to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Santiago de los Caballeros.

Can I find deals for business class flights from Indianapolis to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Indianapolis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$267+ Flights from Indianapolis to Santiago de los Caballeros

Q: How far in advance should I book a flight from Indianapolis to Santiago de los Caballeros?

To save on the cost of your flight from Indianapolis to Santiago de los Caballeros, book at least 8 days before your planned departure. Booking around this time can save you about 80% on the cost of this flight compared to booking a flight leaving this week. We have found prices from $380 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as $865.

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Indianapolis to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Indianapolis to Santiago de los Caballeros are usually found in September or November, booked 7 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Indianapolis to Santiago de los Caballeros

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$429 (Kiwi.com)
One-way from	$267 (Trip.com)
Popular in	December
Cheapest in	September
Average price	$622

Provider with most accurate pricing for Indianapolis-Santiago de los Caballeros flight deals.

Search Deals

Provider most trusted by Cheapflights users for Indianapolis-Santiago de los Caballeros flights.

Search Deals

From Indianapolis to Santiago de los Caballeros

Search Deals

One-way flight from Indianapolis to Santiago de los Caballeros

Search Deals

Highest demand for flights based on searches. 30% potential increase in price ($301 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 18% potential price decrease ($108 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in May 2025

Search Deals

Find flight deals from Indianapolis to Santiago de los Caballeros

Cheapest flights from Indianapolis to Santiago de los Caballeros
Explore the most affordable flight options available from Indianapolis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Sun 5/258:15 amIND - STI

1 stop6h 33mSpirit Airlines

Tue 5/273:53 pmSTI - IND

1 stop7h 22mSpirit Airlines

Deal found 4/30

$429

Sun 5/258:15 amIND - STI

1 stop6h 33mMultiple Airlines

Sun 6/13:53 pmSTI - IND

1 stop21h 46mMultiple Airlines

Deal found 4/30

$444

Wed 5/287:20 pmIND - STI

2 stops19h 40mAmerican Airlines

Tue 7/297:04 amSTI - IND

2 stops15h 18mAmerican Airlines

Deal found 4/30

$519

Mon 5/192:55 pmIND - STI

1 stop9h 19mDelta

Tue 5/276:11 amSTI - IND

1 stop10h 54mDelta

Deal found 4/30

$545

Sat 5/246:51 pmIND - STI

1 stop6h 55mUnited Airlines

Wed 5/286:00 amSTI - IND

1 stop8h 00mUnited Airlines

Deal found 4/30

$735

Best flights from Indianapolis to Santiago de los Caballeros
Discover carefully curated flight deals from Indianapolis to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 1, 2025.

Sun 5/258:15 amIND - STI

1 stop6h 33mSpirit Airlines

Tue 5/273:53 pmSTI - IND

1 stop7h 22mSpirit Airlines

Deal found 4/30

$429

Sun 5/258:15 amIND - STI

1 stop6h 33mMultiple Airlines

Sun 6/13:53 pmSTI - IND

1 stop21h 46mMultiple Airlines

Deal found 4/30

$444

Wed 5/287:20 pmIND - STI

2 stops19h 40mAmerican Airlines

Tue 7/297:04 amSTI - IND

2 stops15h 18mAmerican Airlines

Deal found 4/30

$519

Mon 5/192:55 pmIND - STI

1 stop9h 19mDelta

Tue 5/276:11 amSTI - IND

1 stop10h 54mDelta

Deal found 4/30

$545

Sat 5/246:51 pmIND - STI

1 stop6h 55mUnited Airlines

Wed 5/286:00 amSTI - IND

1 stop8h 00mUnited Airlines

Deal found 4/30

$735

Last-minute flights from Indianapolis to Santiago de los Caballeros
Discover last-minute flight deals from Indianapolis to Santiago de los Caballeros. Data last updated May 1, 2025 and is based on user searches.

Sun 5/117:40 amIND - STI

1 stop7h 32mUnited Airlines

Fri 6/66:00 amSTI - IND

1 stop8h 00mUnited Airlines

Deal found 4/30

$1,309

Mon 5/192:55 pmIND - STI

1 stop9h 19mDelta

Tue 5/276:11 amSTI - IND

1 stop10h 54mDelta

Deal found 4/30

$545

Sat 5/246:51 pmIND - STI

1 stop6h 55mUnited Airlines

Wed 5/286:00 amSTI - IND

1 stop8h 00mUnited Airlines

Deal found 4/30

$735

Sun 5/258:15 amIND - STI

1 stop6h 33mSpirit Airlines

Tue 5/273:53 pmSTI - IND

1 stop7h 22mSpirit Airlines

Deal found 4/30

$429

Sun 5/258:15 amIND - STI

1 stop6h 33mMultiple Airlines

Sun 6/13:53 pmSTI - IND

1 stop21h 46mMultiple Airlines

Deal found 4/30

$444

Wed 5/287:20 pmIND - STI

2 stops19h 40mAmerican Airlines

Tue 7/297:04 amSTI - IND

2 stops15h 18mAmerican Airlines

Deal found 4/30

$519

One-way flights from Indianapolis to Santiago de los Caballeros
Search for one-way flight options from Indianapolis to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated May 1, 2025.

Sun 5/1110:51 amIND - STI

2 stops30h 42mFrontier

Deal found 4/30

$267

Thu 5/86:10 amIND - STI

2 stops8h 50mAmerican Airlines

Deal found 4/30

$281

Sun 5/118:15 amIND - STI

1 stop6h 33mSpirit Airlines

Deal found 4/30

$293

Wed 6/46:20 amIND - STI

1 stop8h 52mUnited Airlines

Deal found 4/30

$321

Sun 5/119:20 amIND - STI

3 stops32h 13mMultiple Airlines

Deal found 4/30

$347

Cheapflights Fare Finder

Use the filters below to find and compare flights from Indianapolis to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Sun 5/25

8:15 am-2:48 pm

1 stop6h 33m

Santiago de los Caballeros

Tue 5/27

3:53 pm-11:15 pm

1 stop7h 22m

$429

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Sun 5/25

8:15 am-2:48 pm

1 stop6h 33m

Santiago de los Caballeros

Sun 6/1

3:53 pm-1:39 pm

1 stop21h 46m

$444

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Wed 5/28

7:20 pm-3:00 pm

2 stops19h 40m

Santiago de los Caballeros

Tue 7/29

7:04 am-10:22 pm

2 stops15h 18m

$519

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Mon 5/19

2:55 pm-12:14 am

1 stop9h 19m

Santiago de los Caballeros

Tue 5/27

6:11 am-5:05 pm

1 stop10h 54m

$545

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Sat 5/24

6:51 pm-1:46 am

1 stop6h 55m

Santiago de los Caballeros

Wed 5/28

6:00 am-2:00 pm

1 stop8h 00m

$735

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Sun 5/11

10:51 am-5:33 pm

2 stops30h 42m

$267

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Thu 5/8

6:10 am-3:00 pm

2 stops8h 50m

$281

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Sun 5/11

8:15 am-2:48 pm

1 stop6h 33m

$293

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Wed 6/4

6:20 am-3:12 pm

1 stop8h 52m

$321

IndianapolisSantiago de los Caballeros

IND - STI

INDSTI

Indianapolis

Sun 5/11

9:20 am-5:33 pm

3 stops32h 13m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/30

Compare providers for flights from Indianapolis to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Santiago de los Caballeros in May.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
Priceline	Price Accuracy2 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Indianapolis-Santiago de los Caballeros flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Indianapolis-Santiago de los Caballeros flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Indianapolis-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Indianapolis-Santiago de los Caballeros flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Indianapolis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Indianapolis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Santiago de los Caballeros

How far ahead should I book a flight from Indianapolis to Santiago de los Caballeros?

Booking 7 days in advance of your planned departure date is, on average, the best time to get cheap flights from Indianapolis to Santiago de los Caballeros. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Indianapolis to Santiago de los Caballeros?

Currently, May is the cheapest month in which you can book a flight from Indianapolis to Santiago de los Caballeros (average of $347). Flying from Indianapolis to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IND to STI?

One of the essential ways to save on airfare from Indianapolis to Santiago de los Caballeros is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the afternoon could potentially save you up to 35% on airfare.

Rainfall in Santiago de los Caballeros by month

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

Temperature in Santiago de los Caballeros by month

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

Reviews of airlines servicing Santiago de los Caballeros

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,934 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,696 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Spirit Airlines

6.3

Okay

7,963 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Frontier

6.0

Okay

3,287 reviews

Delta

8.0

Very good

7,934 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

What are the cheapest airlines flying from Indianapolis to Santiago de los Caballeros round-trip?
Spirit Airlines, at $429, was found to be the cheapest airline from Indianapolis to Santiago de los Caballeros.Alternate airlines to your destination round-trip include American Airlines and Delta. Spirit Airlines is priced at 37% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Indianapolis to Santiago de los Caballeros one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $267. However, be on the lookout for offers from American Airlines and Spirit Airlines, as they are both options that can get you from Indianapolis to Santiago de los Caballeros for a low price.
Can I find deals for flights from Indianapolis to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Indianapolis to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Indianapolis to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indianapolis to Santiago de los Caballeros.
Can I find deals for business class flights from Indianapolis to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Indianapolis to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Indianapolis to Santiago de los Caballeros?
Currently, May is the cheapest month in which you can book a flight from Indianapolis to Santiago de los Caballeros (average of $347). Flying from Indianapolis to Santiago de los Caballeros in July is currently the most expensive (average of $631). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Indianapolis to Santiago de los Caballeros

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$335	Average$567	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$435	Average$592	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$518	Average$699	FlexibilityNo cancel fee	On-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$267+ Cheap flights from Indianapolis (IND) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Indianapolis to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Indianapolis to Santiago de los Caballeros are usually found in September or November, booked 7 days in advance, depart on a Wednesday or Monday and return on a Monday

Cheap flight deals from Indianapolis to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Indianapolis to Santiago de los Caballeros

Cheapest flights from Indianapolis to Santiago de los CaballerosExplore the most affordable flight options available from Indianapolis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Explore the most affordable flight options available from Indianapolis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Indianapolis to Santiago de los Caballeros that are best for you.

Compare providers for flights from Indianapolis to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to Santiago de los Caballeros in May.

Best time to book a flight from Indianapolis to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Indianapolis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Indianapolis to Santiago de los Caballeros

How far ahead should I book a flight from Indianapolis to Santiago de los Caballeros?

Use this chart to determine the optimal time to book a round-trip flight from Indianapolis to Santiago de los Caballeros. Price data was last updated on April 25, 2025.

What is the cheapest month to book a flight from Indianapolis to Santiago de los Caballeros?

What is the cheapest time of day to fly from IND to STI?

Find hourly flight availability from Indianapolis to Santiago de los Caballeros. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 1, 2025.

Rainfall in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average rainfall totals by month.

Temperature in Santiago de los Caballeros by month

Plan your trip to Santiago de los Caballeros by taking into account the average temperature totals by month.

Reviews of airlines servicing Santiago de los Caballeros

Related info for your journey

Find useful and relevant information for your journey from Indianapolis to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Indianapolis to Santiago de los Caballeros round-trip?

What are the cheapest airlines to fly from Indianapolis to Santiago de los Caballeros one-way?

Can I find deals for flights from Indianapolis to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Indianapolis to Santiago de los Caballeros?

Can I find deals for business class flights from Indianapolis to Santiago de los Caballeros?

What is the cheapest month to book a flight from Indianapolis to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Indianapolis to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Indianapolis to Santiago de los Caballeros

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Indianapolis to Santiago de los Caballeros
Explore the most affordable flight options available from Indianapolis to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 1, 2025.