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Santiago de los Caballeros

$218+ Cheap flights from Fort Myers (RSW) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — STI
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Fort Myers to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$461
(JetBlue)

One-way from

$218
(JetBlue)
From Fort Myers SW Florida Intl to Santiago de los Caballeros
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One-way flight from Fort Myers SW Florida Intl to Santiago de los Caballeros
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Find flight deals from Fort Myers to Santiago de los Caballeros

Cheapest flights from Fort Myers to Santiago de los Caballeros
Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This JetBlue deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:13 amRSW - STI
1 stop13h 21mJetBlue
Fri 11/711:59 pmSTI - RSW
1 stop13h 20mJetBlue
Deal found 9/16$461
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2012:27 pmRSW - STI
1 stop25h 04mFrontier
Sun 1/43:29 pmSTI - RSW
1 stop23h 51mFrontier
Deal found 9/15$831
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/207:41 pmRSW - STI
2 stops17h 43mAmerican Airlines
Sun 1/43:24 pmSTI - RSW
2 stops19h 13mAmerican Airlines
Deal found 9/15$1,007
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:37 amRSW - STI
1 stop14h 14mDelta
Mon 1/58:00 pmSTI - RSW
1 stop15h 54mDelta
Deal found 9/15$1,210
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:50 pmRSW - STI
1 stop11h 01mDelta
Mon 1/56:50 amSTI - RSW
1 stop12h 32mDelta
Deal found 9/15$1,235
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:04 pmRSW - STI
1 stop12h 04mDelta
Mon 1/56:50 amSTI - RSW
1 stop12h 32mDelta
Deal found 9/15$1,285
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:50 pmRSW - STI
1 stop8h 49mDelta
Sat 1/33:30 amSTI - RSW
1 stop16h 15mDelta
Deal found 9/15$1,296
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2111:37 amRSW - STI
1 stop12h 02mDelta
Fri 1/23:30 amSTI - RSW
1 stop11h 21mDelta
Deal found 9/15$1,360
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1912:04 pmRSW - STI
1 stop12h 04mDelta
Sun 1/46:25 amSTI - RSW
1 stop13h 20mDelta
Deal found 9/15$1,385

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Fly from

Fort Myers

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 10/31

6:13 am-7:34 pm

1 stop13h 21m

Santiago de los Caballeros

Fri 11/7

11:59 pm-12:19 pm

1 stop13h 20m

$461

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Thu 1/15

7:30 pm-1:08 pm

1 stop16h 38m

Santiago de los Caballeros

Thu 1/22

6:35 am-6:22 pm

1 stop12h 47m

$487

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Thu 1/15

12:15 pm-10:58 pm

1 stop9h 43m

Santiago de los Caballeros

Wed 1/21

4:51 am-6:35 pm

1 stop14h 44m

$491

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Thu 1/15

11:56 am-9:24 pm

2 stops8h 28m

Santiago de los Caballeros

Thu 1/22

7:00 am-8:06 pm

2 stops14h 06m

$522

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sat 12/20

12:27 pm-2:31 pm

1 stop25h 04m

Santiago de los Caballeros

Sun 1/4

3:29 pm-2:20 pm

1 stop23h 51m

$831

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sat 12/20

7:41 pm-2:24 pm

2 stops17h 43m

Santiago de los Caballeros

Sun 1/4

3:24 pm-9:37 am

2 stops19h 13m

$1,007

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sun 12/21

11:37 am-12:39 am

1 stop12h 02m

Santiago de los Caballeros

Sun 1/4

3:35 am-6:22 pm

1 stop15h 47m

$1,210

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sat 12/20

2:50 pm-2:51 am

1 stop11h 01m

Santiago de los Caballeros

Mon 1/5

6:50 am-6:22 pm

1 stop12h 32m

$1,235

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 10/24

3:40 pm-12:34 am

1 stop8h 54m

$218

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 10/24

6:40 am-10:38 am

2 stops27h 58m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 11 results
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Best time to book a flight from Fort Myers to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Fort Myers to Santiago de los Caballeros?

    JetBlue, Delta, and American Airlines can get you from Fort Myers to Santiago de los Caballeros in just under 8h 28m. Your travel time can differ by up to 8h 10m. Airlines will cover a distance of 863 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Fort Myers to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santiago de los Caballeros.

  • Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Fort Myers to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Santiago de los Caballeros?

    Currently, May is the cheapest month in which you can book a flight from Fort Myers to Santiago de los Caballeros (average of $347). Flying from Fort Myers to Santiago de los Caballeros in July is currently the most expensive (average of $600). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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