How long is the flight from Fort Myers to Santiago de los Caballeros?

JetBlue and Spirit Airlines can get you from Fort Myers to Santiago de los Caballeros in just under 7h 21m. Your travel time can differ by up to 16h 52m. Airlines will cover a distance of 863 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What is the cheapest time of day to fly from RSW to STI?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Santiago de los Caballeros as you normally would.

Most accurate provider : When it comes to deals on Fort Myers-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from Fort Myers to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santiago de los Caballeros.

Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Fort Myers to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$195+ Cheap Flights from Fort Myers to Santiago de los Caballeros

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1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

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Cheap flight deals from Fort Myers to Santiago de los Caballeros

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$493 (JetBlue)
One-way from	$195 (Kiwi.com)

Provider with most accurate pricing for Fort Myers SW Florida Intl-Santiago de los Caballeros flight deals.

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Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Santiago de los Caballeros flights.

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From Fort Myers SW Florida Intl to Santiago de los Caballeros

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One-way flight from Fort Myers SW Florida Intl to Santiago de los Caballeros

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Find flight deals from Fort Myers to Santiago de los Caballeros

Cheapest flights from Fort Myers to Santiago de los Caballeros
Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

Wed 11/267:15 pmRSW - STI

1 stop7h 21mJetBlue

Wed 12/36:01 amSTI - RSW

1 stop9h 39mJetBlue

Deal found 11/9

$493

Wed 11/2611:09 amRSW - STI

2 stops24h 13mSpirit Airlines

Wed 12/31:17 pmSTI - RSW

3 stops31h 06mSpirit Airlines

Deal found 11/9

$559

Wed 11/267:15 pmRSW - STI

1 stop25h 38mJetBlue

Mon 5/2510:10 pmSTI - RSW

1 stop13h 12mJetBlue

Deal found 11/9

$649

Wed 12/242:23 pmRSW - STI

1 stop8h 28mUnited Airlines

Wed 12/3112:52 pmSTI - RSW

1 stop9h 53mUnited Airlines

Deal found 11/9

$1,133

Best flights from Fort Myers to Santiago de los Caballeros
Discover carefully curated flight deals from Fort Myers to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2025.

Wed 11/267:15 pmRSW - STI

1 stop7h 21mJetBlue

Wed 12/36:01 amSTI - RSW

1 stop9h 39mJetBlue

Deal found 11/9

$493

Wed 11/2611:09 amRSW - STI

2 stops24h 13mSpirit Airlines

Wed 12/31:17 pmSTI - RSW

3 stops31h 06mSpirit Airlines

Deal found 11/9

$559

Wed 12/242:23 pmRSW - STI

1 stop8h 28mUnited Airlines

Wed 12/3112:52 pmSTI - RSW

1 stop9h 53mUnited Airlines

Deal found 11/9

$1,133

Wed 11/267:15 pmRSW - STI

1 stop25h 38mJetBlue

Mon 5/2510:10 pmSTI - RSW

1 stop13h 12mJetBlue

Deal found 11/9

$649

Last-minute flights from Fort Myers to Santiago de los Caballeros
Discover last-minute flight deals from Fort Myers to Santiago de los Caballeros. Data last updated November 10, 2025 and is based on user searches.

Wed 11/267:15 pmRSW - STI

1 stop7h 21mJetBlue

Wed 12/36:01 amSTI - RSW

1 stop9h 39mJetBlue

Deal found 11/9

$493

Wed 11/2611:09 amRSW - STI

2 stops24h 13mSpirit Airlines

Wed 12/31:17 pmSTI - RSW

3 stops31h 06mSpirit Airlines

Deal found 11/9

$559

Wed 11/267:15 pmRSW - STI

1 stop25h 38mJetBlue

Mon 5/2510:10 pmSTI - RSW

1 stop13h 12mJetBlue

Deal found 11/9

$649

Wed 12/242:23 pmRSW - STI

1 stop8h 28mUnited Airlines

Wed 12/3112:52 pmSTI - RSW

1 stop9h 53mUnited Airlines

Deal found 11/9

$1,133

One-way flights from Fort Myers to Santiago de los Caballeros
Search for one-way flight options from Fort Myers to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated November 10, 2025.

Mon 12/85:45 pmRSW - STI

2 stops31h 57mMultiple Airlines

Deal found 11/10

$195

Wed 11/261:51 pmRSW - STI

3 stops45h 31mMultiple Airlines

Deal found 11/10

$216

Mon 12/86:25 amRSW - STI

3 stops43h 17mSpirit Airlines

Deal found 11/10

$226

Wed 11/2611:09 amRSW - STI

2 stops24h 13mSpirit Airlines

Deal found 11/10

$230

Sun 3/17:25 pmRSW - STI

2 stops19h 10mMultiple Airlines

Deal found 11/9

$240

Sun 3/12:35 pmRSW - STI

3 stops24h 00mSpirit Airlines

Deal found 11/9

$253

Wed 11/267:15 pmRSW - STI

1 stop29h 29mJetBlue

Deal found 11/10

$259

Mon 12/86:00 amRSW - STI

1 stop16h 27mJetBlue

Deal found 11/10

$321

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 11/26

7:15 pm-3:36 am

1 stop7h 21m

Santiago de los Caballeros

Wed 12/3

6:01 am-2:40 pm

1 stop9h 39m

$493

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 11/26

11:09 am-12:22 pm

2 stops24h 13m

Santiago de los Caballeros

Wed 12/3

1:17 pm-7:23 pm

3 stops31h 06m

$559

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 11/26

7:15 pm-9:53 pm

1 stop25h 38m

Santiago de los Caballeros

Mon 5/25

10:10 pm-11:22 am

1 stop13h 12m

$649

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 12/24

2:23 pm-11:51 pm

1 stop8h 28m

Santiago de los Caballeros

Wed 12/31

12:52 pm-9:45 pm

1 stop9h 53m

$1,133

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 12/8

5:45 pm-2:42 am

2 stops31h 57m

$195

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 11/26

1:51 pm-12:22 pm

3 stops45h 31m

$216

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 12/8

6:25 am-2:42 am

3 stops43h 17m

$226

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 11/26

11:09 am-12:22 pm

2 stops24h 13m

$230

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sun 3/1

7:25 pm-3:35 pm

2 stops19h 10m

$240

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sun 3/1

2:35 pm-3:35 pm

3 stops24h 00m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Showing 1-10 of 13 results

Compare providers for flights from Fort Myers to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Santiago de los Caballeros in November.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Fort Myers-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Fort Myers to Santiago de los Caballeros?
JetBlue and Spirit Airlines can get you from Fort Myers to Santiago de los Caballeros in just under 7h 21m. Your travel time can differ by up to 16h 52m. Airlines will cover a distance of 863 mi. This flight may include one or multiple stops.
Can I find deals for flights from Fort Myers to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Fort Myers to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santiago de los Caballeros.
Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Fort Myers to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

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$195+ Cheap flights from Fort Myers (RSW) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Fort Myers to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Find flight deals from Fort Myers to Santiago de los Caballeros

Cheapest flights from Fort Myers to Santiago de los CaballerosExplore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Compare providers for flights from Fort Myers to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Santiago de los Caballeros in November.

Best time to book a flight from Fort Myers to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Fort Myers with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Fort Myers to Santiago de los Caballeros?

Can I find deals for flights from Fort Myers to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Fort Myers to Santiago de los Caballeros?

Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Fort Myers to Santiago de los Caballeros

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Cheapest flights from Fort Myers to Santiago de los Caballeros
Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2025.