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Santiago de los Caballeros

$240+ Cheap flights from Fort Myers (RSW) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/30. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — STI
Mar 5 — Mar 121
Thu 3/5
Thu 3/12
1 adult, Economy
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Cheap flight deals from Fort Myers to Santiago de los Caballeros

Cheapest flights from Fort Myers to Santiago de los Caballeros
Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 3, 2026.

This Mytrip deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/207:51 pm
RSW
-
STI
2 stops18h 44m
Spirit Airlines
Sat 2/284:40 pm
STI
-
RSW
3 stops29h 40m
Spirit Airlines
Deal found 2/3$487
This Expedia deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:50 pm
RSW
-
STI
1 stop7h 45m
JetBlue
Wed 4/298:31 am
STI
-
RSW
2 stops32h 26m
JetBlue
Deal found 2/2$519
This Mytrip deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:20 am
RSW
-
STI
3 stops29h 15m
Multiple Airlines
Wed 4/293:40 pm
STI
-
RSW
2 stops18h 03m
Multiple Airlines
Deal found 2/2$650
This Travelocity deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
RSW
-
STI
1 stop14h 44m
JetBlue
Fri 2/274:35 am
STI
-
RSW
1 stop18h 18m
JetBlue
Deal found 2/3$698
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/205:35 am
RSW
-
STI
2 stops13h 59m
Delta
Sat 2/286:39 am
STI
-
RSW
1 stop13h 11m
Delta
Deal found 2/3$703
This JetBlue deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetBlue is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1810:13 am
RSW
-
STI
1 stop9h 02m
JetBlue
Wed 3/257:10 am
STI
-
RSW
1 stop11h 03m
JetBlue
Deal found 2/1$736
This Orbitz deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:55 pm
RSW
-
STI
2 stops22h 23m
JetBlue
Sat 4/118:45 pm
STI
-
RSW
1 stop12h 50m
JetBlue
Deal found 2/2$815
This United Airlines deal was found by Cheapflights users on 2/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/53:00 pm
RSW
-
STI
1 stop7h 51m
United Airlines
Sat 2/712:52 pm
STI
-
RSW
1 stop10h 07m
United Airlines
Deal found 2/1$819

Find flight deals from Fort Myers to Santiago de los Caballeros

Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Santiago de los Caballeros (STI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 3, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$487
(Mytrip)

One-way from

$240
(Expedia)
Provider with most accurate pricing for Fort Myers SW Florida Intl-Santiago de los Caballeros flight deals.
Search Deals
Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Santiago de los Caballeros flights.
Search Deals
From Fort Myers SW Florida Intl to Santiago de los Caballeros
Search Deals
One-way flight from Fort Myers SW Florida Intl to Santiago de los Caballeros
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Fort Myers to Santiago de los Caballeros that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 3, 2026.
Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Fly from

Fort Myers

Fly to

Santiago de los Caballeros

Route

Depart

Return

Price

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 2/20

7:51 pm-3:35 pm

2 stops18h 44m

Santiago de los Caballeros

Sat 2/28

4:40 pm-9:20 pm

3 stops29h 40m

$487

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sat 4/25

5:50 pm-1:35 am

1 stop7h 45m

Santiago de los Caballeros

Wed 4/29

8:31 am-4:57 pm

2 stops32h 26m

$519

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sat 4/25

9:20 am-2:35 pm

3 stops29h 15m

Santiago de los Caballeros

Wed 4/29

3:40 pm-9:43 am

2 stops18h 03m

$650

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 2/20

6:00 am-9:44 pm

1 stop14h 44m

Santiago de los Caballeros

Fri 2/27

4:35 am-9:53 pm

1 stop18h 18m

$698

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 2/20

5:35 am-8:34 pm

2 stops13h 59m

Santiago de los Caballeros

Sat 2/28

6:39 am-6:50 pm

1 stop13h 11m

$703

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 3/18

10:13 am-7:15 pm

1 stop9h 02m

Santiago de los Caballeros

Wed 3/25

7:10 am-6:13 pm

1 stop11h 03m

$736

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Fri 4/10

6:55 pm-5:18 pm

2 stops22h 23m

Santiago de los Caballeros

Sat 4/11

8:45 pm-9:35 am

1 stop12h 50m

$815

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Sat 4/25

3:42 pm-2:35 pm

2 stops22h 53m

Santiago de los Caballeros

Wed 4/29

3:40 pm-9:43 am

2 stops18h 03m

$946

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Thu 4/30

3:50 pm-12:45 pm

2 stops20h 55m

$240

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Thu 4/30

6:31 am-3:12 pm

1 stop8h 41m

$253

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Showing 1-10 of 11 results
1
2
  • Most accurate provider: When it comes to deals on Fort Myers-Santiago de los Caballeros flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Fort Myers-Santiago de los Caballeros flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Fort Myers-Santiago de los Caballeros flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Fort Myers-Santiago de los Caballeros flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Fort Myers to Santiago de los Caballeros?

    Spirit Airlines and JetBlue can get you from Fort Myers to Santiago de los Caballeros in just under 7h 45m. Your travel time can differ by up to 10h 59m. Airlines will cover a distance of 863 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Fort Myers to Santiago de los Caballeros that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Santiago de los Caballeros?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santiago de los Caballeros.

  • Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?

    Yes. Cheapflights offers flight deals from Fort Myers to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Fort Myers to Santiago de los Caballeros

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