How long is the flight from Fort Myers to Santiago de los Caballeros?

Spirit Airlines and JetBlue can get you from Fort Myers to Santiago de los Caballeros in just under 8h 43m. Your travel time can differ by up to 10h 01m. Airlines will cover a distance of 863 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Santiago de los Caballeros ranges from 3.0 - 11.6 inches per month. December is typically the wettest month, when rainfall can reach 11.6 in. July is typically the driest time to visit Santiago de los Caballeros when rainfall is around 3.0 in.

If weather is an important factor for your trip to Santiago de los Caballeros, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 73.4 F).

What is the cheapest time of day to fly from RSW to STI?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Fort Myers to Santiago de los Caballeros as you normally would.

Most accurate provider : When it comes to deals on Fort Myers-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-Santiago de los Caballeros flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Fort Myers-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

How can I find direct flights from Fort Myers to Santiago de los Caballeros?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santiago de los Caballeros.

Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?

Yes. Cheapflights offers flight deals from Fort Myers to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$189+ Flights from Fort Myers to Santiago de los Caballeros

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Fort Myers to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Fort Myers to Santiago de los Caballeros

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$403 (Mytrip)
One-way from	$189 (Mytrip)

Provider with most accurate pricing for Fort Myers SW Florida Intl-Santiago de los Caballeros flight deals.

Search Deals

Provider most trusted by Cheapflights users for Fort Myers SW Florida Intl-Santiago de los Caballeros flights.

Search Deals

From Fort Myers SW Florida Intl to Santiago de los Caballeros

Search Deals

One-way flight from Fort Myers SW Florida Intl to Santiago de los Caballeros

Search Deals

Find flight deals from Fort Myers to Santiago de los Caballeros

Cheapest flights from Fort Myers to Santiago de los Caballeros
Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

Wed 2/47:49 pmRSW - STI

2 stops18h 44mSpirit Airlines

Sun 2/84:40 pmSTI - RSW

3 stops28h 24mSpirit Airlines

Deal found 1/7

$403

Wed 2/412:10 pmRSW - STI

1 stop8h 43mJetBlue

Sun 2/86:01 amSTI - RSW

1 stop29h 50mJetBlue

Deal found 1/7

$442

Thu 2/56:30 amRSW - STI

2 stops16h 49mJetBlue

Sun 2/86:01 amSTI - RSW

1 stop29h 50mJetBlue

Deal found 1/6

$445

Thu 2/512:10 pmRSW - STI

1 stop11h 09mJetBlue

Sat 2/78:45 amSTI - RSW

1 stop10h 15mJetBlue

Deal found 1/5

$472

Thu 1/1512:10 pmRSW - STI

1 stop8h 43mMultiple Airlines

Thu 1/222:34 pmSTI - RSW

1 stop30h 42mMultiple Airlines

Deal found 1/8

$519

Best flights from Fort Myers to Santiago de los Caballeros
Discover carefully curated flight deals from Fort Myers to Santiago de los Caballeros that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 8, 2026.

Wed 2/47:49 pmRSW - STI

2 stops18h 44mSpirit Airlines

Sun 2/84:40 pmSTI - RSW

3 stops28h 24mSpirit Airlines

Deal found 1/7

$403

Wed 2/412:10 pmRSW - STI

1 stop8h 43mJetBlue

Sun 2/86:01 amSTI - RSW

1 stop29h 50mJetBlue

Deal found 1/7

$442

Tue 3/247:16 amRSW - STI

2 stops13h 13mAmerican Airlines

Thu 3/261:30 pmSTI - RSW

2 stops23h 34mAmerican Airlines

Deal found 1/7

$536

Tue 3/247:00 amRSW - STI

2 stops18h 49mMultiple Airlines

Thu 3/263:40 pmSTI - RSW

3 stops25h 27mMultiple Airlines

Deal found 1/7

$559

Thu 2/510:10 amRSW - STI

1 stop10h 36mJetBlue

Sat 2/76:01 amSTI - RSW

1 stop12h 59mJetBlue

Deal found 1/7

$481

Tue 3/247:14 pmRSW - STI

1 stop25h 46mJetBlue

Wed 3/253:10 amSTI - RSW

1 stop20h 46mJetBlue

Deal found 1/7

$541

Last-minute flights from Fort Myers to Santiago de los Caballeros
Discover last-minute flight deals from Fort Myers to Santiago de los Caballeros. Data last updated January 8, 2026 and is based on user searches.

Thu 1/1512:10 pmRSW - STI

1 stop8h 43mMultiple Airlines

Thu 1/222:34 pmSTI - RSW

1 stop30h 42mMultiple Airlines

Deal found 1/8

$519

Wed 2/47:49 pmRSW - STI

2 stops18h 44mSpirit Airlines

Sun 2/84:40 pmSTI - RSW

3 stops28h 24mSpirit Airlines

Deal found 1/7

$403

Wed 2/412:10 pmRSW - STI

1 stop8h 43mJetBlue

Sun 2/86:01 amSTI - RSW

1 stop29h 50mJetBlue

Deal found 1/7

$442

Thu 2/56:30 amRSW - STI

2 stops16h 49mJetBlue

Sun 2/86:01 amSTI - RSW

1 stop29h 50mJetBlue

Deal found 1/6

$445

Thu 2/512:10 pmRSW - STI

1 stop11h 09mJetBlue

Sat 2/78:45 amSTI - RSW

1 stop10h 15mJetBlue

Deal found 1/5

$472

One-way flights from Fort Myers to Santiago de los Caballeros
Search for one-way flight options from Fort Myers to Santiago de los Caballeros. Find affordable one-way fares based on user searches. Data last updated January 8, 2026.

Mon 2/97:31 amRSW - STI

2 stops31h 02mSpirit Airlines

Deal found 1/7

$189

Mon 2/97:45 pmRSW - STI

3 stops42h 48mMultiple Airlines

Deal found 1/6

$205

Mon 2/910:10 amRSW - STI

1 stop9h 13mJetBlue

Deal found 1/6

$212

Mon 2/911:10 amRSW - STI

2 stops9h 36mAmerican Airlines

Deal found 1/6

$262

Mon 2/93:00 pmRSW - STI

1 stop7h 51mUnited Airlines

Deal found 1/7

$291

Thu 1/153:00 pmRSW - STI

1 stop7h 51mUnited Airlines

Deal found 1/8

$301

Thu 1/1511:28 amRSW - STI

3 stops51h 05mMultiple Airlines

Deal found 1/8

$306

Thu 1/157:31 amRSW - STI

2 stops31h 02mSpirit Airlines

Deal found 1/8

$318

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 2/4

7:49 pm-3:33 pm

2 stops18h 44m

Santiago de los Caballeros

Sun 2/8

4:40 pm-8:04 pm

3 stops28h 24m

$403

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Wed 2/4

12:10 pm-9:53 pm

1 stop8h 43m

Santiago de los Caballeros

Sun 2/8

6:01 am-10:51 am

1 stop29h 50m

$442

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Thu 2/5

10:10 am-9:46 pm

1 stop10h 36m

Santiago de los Caballeros

Sat 2/7

6:01 am-6:00 pm

1 stop12h 59m

$481

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Tue 3/24

7:16 am-8:29 pm

2 stops13h 13m

Santiago de los Caballeros

Thu 3/26

1:30 pm-1:04 pm

2 stops23h 34m

$536

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Tue 3/24

7:14 pm-9:00 pm

1 stop25h 46m

Santiago de los Caballeros

Wed 3/25

3:10 am-11:56 pm

1 stop20h 46m

$541

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Tue 3/24

7:00 am-1:49 am

2 stops18h 49m

Santiago de los Caballeros

Thu 3/26

3:40 pm-5:07 pm

3 stops25h 27m

$559

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 2/9

7:31 am-3:33 pm

2 stops31h 02m

$189

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 2/9

7:45 pm-3:33 pm

3 stops42h 48m

$205

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 2/9

10:10 am-8:23 pm

1 stop9h 13m

$224

Fort MyersSantiago de los Caballeros

RSW - STI

RSWSTI

Fort Myers SW Florida Intl

Mon 2/9

3:00 pm-11:51 pm

1 stop7h 51m

$291

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/7

Showing 1-10 of 16 results

Compare providers for flights from Fort Myers to Santiago de los Caballeros

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Santiago de los Caballeros in January.

Provider	Price Accuracy	Trust Score*
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Fort Myers-Santiago de los Caballeros flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Fort Myers-Santiago de los Caballeros flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Fort Myers-Santiago de los Caballeros flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Fort Myers-Santiago de los Caballeros flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Fort Myers-Santiago de los Caballeros flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Fort Myers to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Fort Myers with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

How long is the flight from Fort Myers to Santiago de los Caballeros?
Spirit Airlines and JetBlue can get you from Fort Myers to Santiago de los Caballeros in just under 8h 43m. Your travel time can differ by up to 10h 01m. Airlines will cover a distance of 863 mi. This flight may include one or multiple stops.
Can I find deals for flights from Fort Myers to Santiago de los Caballeros that include hotel bookings?
Yes. In addition to deals on Fort Myers to Santiago de los Caballeros flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Fort Myers to Santiago de los Caballeros?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Santiago de los Caballeros.
Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?
Yes. Cheapflights offers flight deals from Fort Myers to Santiago de los Caballeros by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$189+ Cheap flights from Fort Myers (RSW) to Santiago de los Caballeros (STI)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/9. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Fort Myers to Santiago de los Caballeros with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Fort Myers to Santiago de los Caballeros

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Find flight deals from Fort Myers to Santiago de los Caballeros

Cheapest flights from Fort Myers to Santiago de los CaballerosExplore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Fort Myers to Santiago de los Caballeros that are best for you.

Compare providers for flights from Fort Myers to Santiago de los Caballeros

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Fort Myers to Santiago de los Caballeros in January.

Best time to book a flight from Fort Myers to Santiago de los Caballeros

Have a flexible travel schedule? Discover the best time to fly to Santiago de los Caballeros from Fort Myers with our price prediction graph.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Santiago de los Caballeros. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Fort Myers to Santiago de los Caballeros?

Can I find deals for flights from Fort Myers to Santiago de los Caballeros that include hotel bookings?

How can I find direct flights from Fort Myers to Santiago de los Caballeros?

Can I find deals for business class flights from Fort Myers to Santiago de los Caballeros?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Fort Myers to Santiago de los Caballeros

See prices for flight routes from nearby airports that may be better suited for you.

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Fort Myers to Santiago de los Caballeros
Explore the most affordable flight options available from Fort Myers to Santiago de los Caballeros. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 8, 2026.