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$641+ Cheap flights from Santa Ana, CA (SNA) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/5. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — SCL
Jan 11 — Jan 181
Sun 1/11
Sun 1/18
1 adult, Economy
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Cheap flight deals from Santa Ana to Santiago

Cheapest flights from Santa Ana to Santiago
Explore the most affordable flight options available from Santa Ana to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/249:59 amSNA - SCL
2 stops18h 26mAmerican Airlines
Mon 12/2911:55 pmSCL - SNA
2 stops20h 26mAmerican Airlines
Deal found 12/11$1,049
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/258:17 amSNA - SCL
2 stops20h 08mAmerican Airlines
Mon 12/2911:55 pmSCL - SNA
2 stops20h 26mAmerican Airlines
Deal found 12/11$1,099
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:30 amSNA - SCL
1 stop18h 15mAmerican Airlines
Mon 12/2211:15 pmSCL - SNA
1 stop15h 43mAmerican Airlines
Deal found 12/10$1,134
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/117:00 amSNA - SCL
2 stops20h 50mUnited Airlines
Mon 12/2210:45 pmSCL - SNA
2 stops23h 45mUnited Airlines
Deal found 12/10$1,189
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:23 pmSNA - SCL
2 stops33h 27mUnited Airlines
Mon 12/2910:45 pmSCL - SNA
1 stop28h 10mUnited Airlines
Deal found 12/11$1,271
This United Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:19 pmSNA - SCL
1 stop15h 31mUnited Airlines
Mon 12/2910:45 pmSCL - SNA
1 stop17h 38mUnited Airlines
Deal found 12/11$1,406
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/256:45 amSNA - SCL
1 stop19h 55mDelta
Mon 12/2911:10 pmSCL - SNA
1 stop18h 55mDelta
Deal found 12/11$1,461
This Mytrip deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2411:11 amSNA - SCL
3 stops37h 19mMultiple Airlines
Sun 12/281:35 amSCL - SNA
3 stops25h 36mMultiple Airlines
Deal found 12/11$1,484
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2412:05 pmSNA - SCL
1 stop14h 35mDelta
Mon 12/299:30 pmSCL - SNA
1 stop20h 35mDelta
Deal found 12/11$1,538
This SmartFares deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure SmartFares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/196:45 amSNA - SCL
1 stop18h 25mLATAM Airlines
Sat 12/279:30 pmSCL - SNA
1 stop29h 46mLATAM Airlines
Deal found 12/10$1,584
This Expedia deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/252:16 pmSNA - SCL
2 stops40h 59mMultiple Airlines
Mon 12/298:15 amSCL - SNA
3 stops31h 39mMultiple Airlines
Deal found 12/11$2,100

Find flight deals from Santa Ana to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$1,224
(LATAM Airlines)

One-way from

$641
(SmartFares)

Popular in

December

Cheapest in

May

Average price

$1,148
Provider with most accurate pricing for Santa Ana J. Wayne/Orange Cnty-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santa Ana J. Wayne/Orange Cnty-Santiago Arturo Merino Benitez flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 11% potential increase in price ($106 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 12, 2025.
Use the filters below to find and compare flights from Santa Ana to Santiago that are best for you.

Fly from

Santa Ana

Fly to

Santiago

Route

Depart

Return

Price

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Wed 12/24

9:59 am-9:25 am

2 stops18h 26m

Santiago Arturo Merino Benitez

Mon 12/29

11:55 pm-3:21 pm

2 stops20h 26m

$1,049

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 3/30

11:55 am-8:00 am

1 stop16h 05m

Santiago Arturo Merino Benitez

Wed 4/1

7:45 pm-7:42 pm

2 stops27h 57m

$1,224

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Thu 12/25

6:23 pm-8:50 am

2 stops33h 27m

Santiago Arturo Merino Benitez

Mon 12/29

10:45 pm-9:55 pm

1 stop28h 10m

$1,271

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Thu 1/8

12:23 pm-8:50 am

1 stop15h 27m

Santiago Arturo Merino Benitez

Mon 1/12

10:45 pm-2:07 pm

1 stop20h 22m

$1,294

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Thu 3/5

12:04 pm-7:40 am

1 stop14h 36m

$641

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Tue 1/13

6:45 am-7:40 am

1 stop19h 55m

$641

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Tue 2/3

11:55 am-7:40 am

1 stop14h 45m

$641

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Wed 1/28

6:45 am-7:40 am

1 stop19h 55m

$641

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Sat 3/21

6:45 am-7:40 am

1 stop20h 55m

$681

Santa AnaSantiago

SNA - SCL

SNASCL

Santa Ana J. Wayne/Orange Cnty

Mon 1/5

6:45 am-7:40 am

1 stop19h 55m

$691

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 16 results
1
2

Compare providers for flights from Santa Ana to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Santiago in December.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santa Ana, California-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Santa Ana, California-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Santa Ana, California-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santa Ana, California-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana, California-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santa Ana to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Santiago

What is the cheapest month to book a flight from Santa Ana, California to Santiago?

Currently, May is the cheapest month in which you can book a flight from Santa Ana, California to Santiago (average of $482). Flying from Santa Ana, California to Santiago in December is currently the most expensive (average of $692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Ana, California to Santiago?

    For as low as $1,224, American Airlines can have you in Santiago from Santa Ana, California in 16h 05m. Airlines will cover a distance of 5547 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Santa Ana to Santiago that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Santiago.

  • Can I find deals for business class flights from Santa Ana to Santiago?

    Yes. Cheapflights offers flight deals from Santa Ana to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Santa Ana, California to Santiago (average of $482). Flying from Santa Ana, California to Santiago in December is currently the most expensive (average of $692). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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