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$406+ Cheap flights from San Diego (SAN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/9. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from San Diego to Santiago Arturo Merino Benitez are usually found in September or November, booked 79 days in advance, depart on a Sunday or Saturday and return on a Friday

Cheap flight deals from San Diego to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$828
(Mytrip)

One-way from

$408
(Kiwi.com)

Popular in

June

Cheapest in

September

Average price

$1,175
From San Diego to Santiago Arturo Merino Benitez
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One-way flight from San Diego to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 8% potential increase in price ($94 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($15 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from San Diego to Santiago

Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/19:12 pmSAN - SCL
1 stop22h 52mCopa Airlines
Mon 10/135:10 amSCL - SAN
1 stop16h 47mCopa Airlines
Deal found 6/10$454
This Justfly.com deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2010:00 amSAN - SCL
1 stop16h 00mLATAM Airlines
Fri 10/318:15 amSCL - SAN
1 stop18h 39mLATAM Airlines
Deal found 6/11$783
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/86:15 amSAN - SCL
2 stops18h 30mDelta
Tue 1/1311:55 pmSCL - SAN
1 stop14h 24mDelta
Deal found 6/12$804
This Mytrip deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/93:57 pmSAN - SCL
3 stops26h 18mMultiple Airlines
Wed 7/162:30 pmSCL - SAN
3 stops33h 15mMultiple Airlines
Deal found 6/12$828
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/17:13 amSAN - SCL
2 stops20h 52mAmerican Airlines
Mon 10/139:55 pmSCL - SAN
2 stops20h 56mAmerican Airlines
Deal found 6/10$846
This Air Canada deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/911:50 amSAN - SCL
1 stop19h 20mAir Canada
Mon 1/128:50 pmSCL - SAN
1 stop19h 03mAir Canada
Deal found 6/12$1,008
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:15 pmSAN - SCL
3 stops34h 35mUnited Airlines
Tue 1/1310:45 pmSCL - SAN
2 stops24h 04mUnited Airlines
Deal found 6/12$1,103

Cheapflights Fare Finder

Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

San Diego

Fly to

Santiago

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 10/1

9:12 pm-12:04 am

1 stop22h 52m

Santiago Arturo Merino Benitez

Mon 10/13

5:10 am-5:57 pm

1 stop16h 47m

$454

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 10/20

10:00 am-6:00 am

1 stop16h 00m

Santiago Arturo Merino Benitez

Fri 10/31

8:15 am-10:54 pm

1 stop18h 39m

$783

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 12/8

6:15 am-5:45 am

2 stops18h 30m

Santiago Arturo Merino Benitez

Tue 1/13

11:55 pm-9:19 am

1 stop14h 24m

$804

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 7/9

3:57 pm-9:15 pm

3 stops26h 18m

Santiago Arturo Merino Benitez

Wed 7/16

2:30 pm-8:45 pm

3 stops33h 15m

$828

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 10/1

7:13 am-8:05 am

2 stops20h 52m

Santiago Arturo Merino Benitez

Mon 10/13

9:55 pm-2:51 pm

2 stops20h 56m

$846

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 12/9

11:50 am-12:10 pm

1 stop19h 20m

Santiago Arturo Merino Benitez

Mon 1/12

8:50 pm-10:53 am

1 stop19h 03m

$1,008

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 12/8

5:15 pm-8:50 am

3 stops34h 35m

Santiago Arturo Merino Benitez

Tue 1/13

10:45 pm-5:49 pm

2 stops24h 04m

$1,103

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 12/9

8:20 am-4:51 am

3 stops39h 31m

$406

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sat 11/22

8:10 pm-12:10 pm

2 stops35h 00m

$474

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 8/28

9:00 am-6:45 am

1 stop18h 45m

$518

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 11 results
1
2

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Santiago. Price data was last updated on June 9, 2025.

Booking 77 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $752). Flying from San Diego to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SCL?

Find hourly flight availability from San Diego to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from San Diego to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 18% versus a flight in the afternoon.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Iberia
7.0
Good
2,776 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Comfort

7.9

Overall

8.0

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Diego to Santiago round-trip?

    Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $831 on this airline. Additional options worth looking into are LATAM Airlines and Delta, starting at $836 and $874 round-trip. You may be able to fly from San Diego to Santiago for 17% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Diego to Santiago that include hotel bookings?

    Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.

  • Can I find deals for business class flights from San Diego to Santiago?

    Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $752). Flying from San Diego to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Diego to Santiago

Discover the top 5 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$453Average$854FlexibilityNo cancel feeOn-time70%
United AirlinesCheapest$542Average$938FlexibilityNo cancel feeOn-time69%
LATAM AirlinesCheapest$792Average$1,041FlexibilityNo cancel feeOn-time81%
DeltaCheapest$792Average$1,003FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$822Average$1,045FlexibilityNo cancel feeOn-time71%

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