How long is the flight from San Diego to Santiago?

Copa Airlines and United Airlines can get you from San Diego to Santiago in just under 15h 43m. Your travel time can differ by up to 7h 15m. The distance from San Diego to Santiago is about 5471 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from San Diego to Santiago round-trip?

Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $453 on this airline. Additional options worth looking into are United Airlines and LATAM Airlines, starting at $542 and $556 round-trip. You may be able to fly from San Diego to Santiago for 54% less than the average price by searching for these airlines.

What is the cheapest day to fly from San Diego to Santiago?

Travelers seeking maximum savings on their San Diego to Santiago flight should consider departing on Wednesday at noon when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What are the most popular airlines that fly from San Diego to Santiago?

American Airlines, Copa Airlines and Delta are the most popular airlines when flying from San Diego to Santiago.

What is the cheapest day to fly round-trip from San Diego to Santiago?

Travelers have found that booking a Saturday departure is the best way to save up to 12% on the cost of booking your flights compared to booking on days of the week where this route is of high demand.

How far in advance should I book a flight from San Diego to Santiago?

Find a great deal and save up to 122% by booking at least 42 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from San Diego to Santiago within the next two weeks, with the cheapest ticket starting at $792.

What is the cheapest month to fly from San Diego to Santiago?

Our data shows that October tends to be the cheapest month to fly to Santiago from San Diego. Users have commonly found prices around $996 for the month, but tickets can be as low as $495. Due to multiple factors, prepare for potentially higher prices in June.

Can I find deals for flights from San Diego to Santiago that include hotel bookings?

Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Diego to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.

Can I find deals for business class flights from San Diego to Santiago?

Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$260+ Flights from San Diego to Santiago

Q: How much does it cost to fly round-trip from San Diego to Santiago?

Airfare is below average for this route at the moment. San Diego to Santiago flights typically cost between $554 and $893 in October. The cheapest round-trip price found within the last 3 days was $502 on Copa Airlines (Oct 20-Oct 29).

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Find cheap flights from San Diego to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from San Diego to Santiago Arturo Merino Benitez are usually found in October or November, booked 41 days in advance, depart on a Sunday or Saturday and return on a Friday

Cheap flight deals from San Diego to Santiago

Round-trip from	$502 (Copa Airlines)
One-way from	$260 (Copa Airlines)
Popular in	June
Cheapest in	October
Average price	$843

From San Diego to Santiago Arturo Merino Benitez

Search Deals

One-way flight from San Diego to Santiago Arturo Merino Benitez

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Highest demand for flights based on searches. 8% potential increase in price ($89 potential increase over avg. RT price).

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Cheapest flight prices on average. 1% potential price decrease ($17 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from San Diego to Santiago

Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Mon 10/209:12 pmSAN - SCL

1 stop22h 28mCopa Airlines

Wed 10/295:11 amSCL - SAN

1 stop16h 46mCopa Airlines

Deal found 9/10

$502

Sat 10/256:15 amSAN - SCL

1 stop21h 35mUnited Airlines

Sun 11/210:45 pmSCL - SAN

1 stop22h 40mUnited Airlines

Deal found 9/10

$514

Sun 10/267:07 amSAN - SCL

1 stop20h 58mAmerican Airlines

Sun 11/211:15 pmSCL - SAN

1 stop23h 50mAmerican Airlines

Deal found 9/10

$517

Fri 10/248:39 pmSAN - SCL

2 stops31h 11mUnited Airlines

Sun 11/210:45 pmSCL - SAN

2 stops21h 15mUnited Airlines

Deal found 9/10

$518

Sun 10/265:50 pmSAN - SCL

1 stop34h 00mUnited Airlines

Sun 11/210:45 pmSCL - SAN

1 stop24h 39mUnited Airlines

Deal found 9/10

$522

Thu 10/238:39 pmSAN - SCL

2 stops55h 11mUnited Airlines

Fri 10/319:45 pmSCL - SAN

2 stops27h 03mUnited Airlines

Deal found 9/10

$532

Wed 9/109:08 pmSAN - SCL

1 stop19h 12mCopa Airlines

Wed 9/245:22 amSCL - SAN

1 stop16h 28mCopa Airlines

Deal found 9/10

$542

Wed 9/1010:45 pmSAN - SCL

1 stop29h 10mAmerican Airlines

Wed 9/249:55 pmSCL - SAN

2 stops24h 07mAmerican Airlines

Deal found 9/10

$569

Tue 10/216:15 amSAN - SCL

2 stops20h 40mLATAM Airlines

Sun 11/211:10 pmSCL - SAN

1 stop18h 25mLATAM Airlines

Deal found 9/10

$574

Wed 10/226:15 amSAN - SCL

2 stops19h 45mLATAM Airlines

Tue 10/288:15 amSCL - SAN

2 stops18h 51mLATAM Airlines

Deal found 9/10

$578

Wed 10/229:12 pmSAN - SCL

1 stop22h 28mMultiple Airlines

Sat 11/111:55 pmSCL - SAN

1 stop14h 25mMultiple Airlines

Deal found 9/10

$593

Sun 10/268:00 amSAN - SCL

1 stop19h 50mUnited Airlines

Tue 10/289:45 pmSCL - SAN

1 stop24h 39mUnited Airlines

Deal found 9/10

$594

Best flights from San Diego to Santiago
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 11, 2025.

Sun 10/269:07 pmSAN - SCL

1 stop22h 58mCopa Airlines

Sat 11/13:23 amSCL - SAN

1 stop18h 40mCopa Airlines

Deal found 9/10

$502

Thu 11/612:07 pmSAN - SCL

1 stop15h 43mUnited Airlines

Wed 11/1210:45 pmSCL - SAN

1 stop22h 40mUnited Airlines

Deal found 9/10

$514

Mon 10/271:47 pmSAN - SCL

1 stop14h 03mUnited Airlines

Mon 11/310:45 pmSCL - SAN

1 stop17h 16mUnited Airlines

Deal found 9/10

$514

Sat 10/2510:15 amSAN - SCL

1 stop17h 35mUnited Airlines

Thu 10/309:45 pmSCL - SAN

1 stop22h 40mUnited Airlines

Deal found 9/10

$514

Sat 10/258:00 amSAN - SCL

1 stop19h 50mUnited Airlines

Mon 11/310:45 pmSCL - SAN

1 stop17h 16mUnited Airlines

Deal found 9/10

$514

Mon 10/2711:20 amSAN - SCL

2 stops16h 30mUnited Airlines

Wed 10/299:45 pmSCL - SAN

1 stop22h 40mUnited Airlines

Deal found 9/10

$518

Mon 10/2711:20 amSAN - SCL

2 stops16h 30mUnited Airlines

Thu 10/309:45 pmSCL - SAN

2 stops19h 19mUnited Airlines

Deal found 9/10

$518

Sat 10/2511:08 amSAN - SCL

2 stops16h 42mUnited Airlines

Sat 11/110:45 pmSCL - SAN

2 stops21h 10mUnited Airlines

Deal found 9/10

$518

Sun 10/268:40 pmSAN - SCL

2 stops31h 10mUnited Airlines

Sun 11/210:45 pmSCL - SAN

2 stops21h 10mUnited Airlines

Deal found 9/10

$518

Sun 10/268:40 pmSAN - SCL

2 stops31h 10mUnited Airlines

Thu 10/309:45 pmSCL - SAN

1 stop22h 40mUnited Airlines

Deal found 9/10

$518

Sun 10/268:40 pmSAN - SCL

2 stops31h 10mUnited Airlines

Sat 11/110:45 pmSCL - SAN

1 stop22h 40mUnited Airlines

Deal found 9/10

$518

Last-minute flights from San Diego to Santiago
Discover last-minute flight deals from San Diego to Santiago. Data last updated September 11, 2025 and is based on user searches.

Mon 10/209:12 pmSAN - SCL

1 stop22h 28mCopa Airlines

Wed 10/295:11 amSCL - SAN

1 stop16h 46mCopa Airlines

Deal found 9/10

$502

Tue 10/216:15 amSAN - SCL

2 stops20h 40mLATAM Airlines

Sun 11/211:10 pmSCL - SAN

1 stop18h 25mLATAM Airlines

Deal found 9/10

$574

Wed 10/226:15 amSAN - SCL

2 stops19h 45mLATAM Airlines

Tue 10/288:15 amSCL - SAN

2 stops18h 51mLATAM Airlines

Deal found 9/10

$578

Wed 10/229:12 pmSAN - SCL

1 stop22h 28mMultiple Airlines

Mon 11/311:55 pmSCL - SAN

1 stop14h 25mMultiple Airlines

Deal found 9/10

$593

Wed 10/229:12 pmSAN - SCL

1 stop19h 08mMultiple Airlines

Fri 10/3110:10 pmSCL - SAN

1 stop18h 25mMultiple Airlines

Deal found 9/10

$596

Wed 10/229:12 pmSAN - SCL

1 stop22h 28mMultiple Airlines

Sun 11/211:55 pmSCL - SAN

1 stop14h 25mMultiple Airlines

Deal found 9/10

$597

Thu 10/238:39 pmSAN - SCL

2 stops55h 11mUnited Airlines

Fri 10/319:45 pmSCL - SAN

2 stops27h 03mUnited Airlines

Deal found 9/10

$532

Fri 10/248:39 pmSAN - SCL

2 stops31h 11mUnited Airlines

Sun 11/210:45 pmSCL - SAN

2 stops21h 15mUnited Airlines

Deal found 9/10

$518

Sat 10/256:15 amSAN - SCL

1 stop21h 35mUnited Airlines

Sun 11/210:45 pmSCL - SAN

1 stop22h 40mUnited Airlines

Deal found 9/10

$514

Sun 10/267:07 amSAN - SCL

1 stop20h 58mAmerican Airlines

Sun 11/211:15 pmSCL - SAN

1 stop23h 50mAmerican Airlines

Deal found 9/10

$517

Sun 10/265:50 pmSAN - SCL

1 stop34h 00mUnited Airlines

Fri 10/319:45 pmSCL - SAN

1 stop24h 39mUnited Airlines

Deal found 9/10

$522

Sun 10/268:00 amSAN - SCL

1 stop19h 50mUnited Airlines

Tue 10/289:45 pmSCL - SAN

1 stop24h 39mUnited Airlines

Deal found 9/10

$594

One-way flights from San Diego to Santiago
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated September 11, 2025.

Wed 10/229:12 pmSAN - SCL

1 stop19h 08mCopa Airlines

Deal found 9/11

$260

Wed 10/226:25 amSAN - SCL

2 stops19h 35mDelta

Deal found 9/11

$268

Wed 10/226:41 amSAN - SCL

3 stops35h 34mMultiple Airlines

Deal found 9/11

$338

Sun 12/144:52 pmSAN - SCL

3 stops31h 38mMultiple Airlines

Deal found 9/11

$432

Sun 12/146:15 amSAN - SCL

1 stop20h 25mDelta

Deal found 9/11

$543

Sat 12/2010:58 pmSAN - SCL

2 stops51h 42mLATAM Airlines

Deal found 9/10

$1,305

Sat 12/205:02 pmSAN - SCL

2 stops19h 08mDelta

Deal found 9/11

$1,353

Sat 12/2010:58 pmSAN - SCL

3 stops48h 37mMultiple Airlines

Deal found 9/10

$1,413

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 10/26

9:07 pm-12:05 am

1 stop22h 58m

Santiago Arturo Merino Benitez

Sat 11/1

3:23 am-6:03 pm

1 stop18h 40m

$502

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 11/6

12:07 pm-8:50 am

1 stop15h 43m

Santiago Arturo Merino Benitez

Wed 11/12

10:45 pm-4:25 pm

1 stop22h 40m

$514

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 10/27

1:47 pm-7:50 am

1 stop14h 03m

Santiago Arturo Merino Benitez

Mon 11/3

10:45 pm-11:01 am

1 stop17h 16m

$514

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sat 10/25

10:15 am-7:50 am

1 stop17h 35m

Santiago Arturo Merino Benitez

Thu 10/30

9:45 pm-4:25 pm

1 stop22h 40m

$514

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sat 10/25

8:00 am-7:50 am

1 stop19h 50m

Santiago Arturo Merino Benitez

Mon 11/3

10:45 pm-11:01 am

1 stop17h 16m

$514

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 10/27

11:20 am-7:50 am

2 stops16h 30m

Santiago Arturo Merino Benitez

Wed 10/29

9:45 pm-4:25 pm

1 stop22h 40m

$518

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 10/27

11:20 am-7:50 am

2 stops16h 30m

Santiago Arturo Merino Benitez

Thu 10/30

9:45 pm-1:04 pm

2 stops19h 19m

$518

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sat 10/25

11:08 am-7:50 am

2 stops16h 42m

Santiago Arturo Merino Benitez

Sat 11/1

10:45 pm-3:55 pm

2 stops21h 10m

$518

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 10/26

8:40 pm-7:50 am

2 stops31h 10m

Santiago Arturo Merino Benitez

Sun 11/2

10:45 pm-2:55 pm

2 stops21h 10m

$518

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sun 10/26

8:40 pm-7:50 am

2 stops31h 10m

Santiago Arturo Merino Benitez

Thu 10/30

9:45 pm-4:25 pm

1 stop22h 40m

$518

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 19 results

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $752). Flying from San Diego to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SCL?

When flying from San Diego to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 18% versus a flight in the afternoon.

How much does it cost to fly round-trip from San Diego to Santiago?

Reviews of airlines servicing Santiago

See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

8.0

Very good

7,960 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.6

Good

1,531 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,847 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

8,937 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,960 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

How long is the flight from San Diego to Santiago?
Copa Airlines and United Airlines can get you from San Diego to Santiago in just under 15h 43m. Your travel time can differ by up to 7h 15m. The distance from San Diego to Santiago is about 5471 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from San Diego to Santiago round-trip?
Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $453 on this airline. Additional options worth looking into are United Airlines and LATAM Airlines, starting at $542 and $556 round-trip. You may be able to fly from San Diego to Santiago for 54% less than the average price by searching for these airlines.
Can I find deals for flights from San Diego to Santiago that include hotel bookings?
Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Diego to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.
Can I find deals for business class flights from San Diego to Santiago?
Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $752). Flying from San Diego to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Santiago

Top 5 airlines flying from San Diego to Santiago

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$453	Average$820	FlexibilityNo cancel fee	On-time70%
United Airlines	Cheapest$542	Average$938	FlexibilityNo cancel fee	On-time69%
LATAM Airlines	Cheapest$556	Average$940	FlexibilityNo cancel fee	On-time81%
American Airlines	Cheapest$599	Average$1,026	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$792	Average$962	FlexibilityNo cancel fee	On-timeN/A

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$260+ Cheap flights from San Diego (SAN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Diego to Santiago with Cheapflights

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Cheapflights Tip: The best prices from San Diego to Santiago Arturo Merino Benitez are usually found in October or November, booked 41 days in advance, depart on a Sunday or Saturday and return on a Friday

Cheap flight deals from San Diego to Santiago

Round-trip from

One-way from

Popular in

Cheapest in

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Find flight deals from San Diego to Santiago

Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

What is the cheapest month to book a flight from San Diego to Santiago?

What is the cheapest time of day to fly from SAN to SCL?

How much does it cost to fly round-trip from San Diego to Santiago?

Reviews of airlines servicing Santiago

See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from San Diego to Santiago?

What are the cheapest airlines flying from San Diego to Santiago round-trip?

Can I find deals for flights from San Diego to Santiago that include hotel bookings?

How can I find direct flights from San Diego to Santiago?

Can I find deals for business class flights from San Diego to Santiago?

What is the cheapest month to book a flight from San Diego to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Diego to Santiago

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Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.