$303+ Cheap flights from San Diego (SAN) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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Best
Last-minute
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Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This FlightHub deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:20 am
SAN
- SCL
2 stops19h 30m
LATAM Airlines
Fri 4/247:55 pm
SCL
- SAN
2 stops21h 55m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$711
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:18 pm
SAN
- SCL
1 stop19h 05m
Copa Airlines
Thu 4/2312:09 am
SCL
- SAN
1 stop21h 21m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$743
This Gurufare deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:15 am
SAN
- SCL
2 stops20h 30m
LATAM Airlines
Tue 4/288:40 pm
SCL
- SAN
1 stop16h 09m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$755
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:15 am
SAN
- SCL
3 stops28h 10m
LATAM Airlines
Sun 4/2611:05 pm
SCL
- SAN
2 stops22h 34m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$760
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:18 pm
SAN
- SCL
1 stop22h 25m
Copa Airlines
Sun 4/124:17 am
SCL
- SAN
1 stop17h 13m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$763
This Orbitz deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:40 am
SAN
- SCL
2 stops24h 05m
LATAM Airlines
Mon 4/138:30 am
SCL
- SAN
3 stops31h 30m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$785
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/283:59 pm
SAN
- SCL
2 stops18h 06m
LATAM Airlines
Wed 10/77:45 am
SCL
- SAN
2 stops19h 10m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$786
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am
SAN
- SCL
1 stop19h 20m
LATAM Airlines
Wed 11/44:25 pm
SCL
- SAN
2 stops27h 55m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$795
Best flights from San Diego to SantiagoDiscover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/229:18 pm
SAN
- SCL
1 stop23h 08m
Copa Airlines
Tue 4/282:30 am
SCL
- SAN
1 stop19h 00m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$743
This LATAM Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:20 am
SAN
- SCL
3 stops24h 44m
LATAM Airlines
Tue 4/2811:05 pm
SCL
- SAN
2 stops22h 34m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$755
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:15 am
SAN
- SCL
1 stop22h 00m
Delta
Mon 4/137:55 pm
SCL
- SAN
2 stops23h 43m
Delta
Deal found 3/9![Delta logo]()
$906
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:18 pm
SAN
- SCL
1 stop19h 05m
Copa Airlines
Thu 4/2312:09 am
SCL
- SAN
1 stop21h 21m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$743
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:15 am
SAN
- SCL
3 stops28h 10m
LATAM Airlines
Sun 4/268:40 pm
SCL
- SAN
1 stop16h 09m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$760
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:18 pm
SAN
- SCL
1 stop22h 25m
Copa Airlines
Sun 4/124:17 am
SCL
- SAN
1 stop17h 13m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$763
This Orbitz deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:40 am
SAN
- SCL
2 stops24h 05m
LATAM Airlines
Mon 4/138:30 am
SCL
- SAN
3 stops31h 30m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$785
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:00 pm
SAN
- SCL
2 stops23h 35m
LATAM Airlines
Sat 8/811:25 pm
SCL
- SAN
1 stop22h 29m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$875
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:18 pm
SAN
- SCL
1 stop19h 05m
Copa Airlines
Thu 4/302:22 am
SCL
- SAN
1 stop19h 08m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$896
This Copa Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:18 pm
SAN
- SCL
1 stop19h 05m
Copa Airlines
Wed 4/154:17 am
SCL
- SAN
1 stop17h 13m
Copa Airlines
Deal found 3/11![Copa Airlines logo]()
$916
Last-minute flights from San Diego to SantiagoDiscover last-minute flight deals from San Diego to Santiago. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Diego to Santiago. Data last updated March 12, 2026 and is based on user searches.
This Orbitz deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:40 pm
SAN
- SCL
1 stop18h 35m
Multiple Airlines
Fri 5/18:40 pm
SCL
- SAN
1 stop26h 00m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$906
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/59:18 pm
SAN
- SCL
1 stop22h 25m
Copa Airlines
Sun 4/124:17 am
SCL
- SAN
1 stop17h 13m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$763
This Orbitz deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/610:40 am
SAN
- SCL
2 stops24h 05m
LATAM Airlines
Mon 4/138:30 am
SCL
- SAN
3 stops31h 30m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$785
This Copa Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/89:18 pm
SAN
- SCL
1 stop19h 05m
Copa Airlines
Wed 4/154:17 am
SCL
- SAN
1 stop17h 13m
Copa Airlines
Deal found 3/11![Copa Airlines logo]()
$916
This FlightHub deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:20 am
SAN
- SCL
1 stop20h 15m
LATAM Airlines
Thu 4/167:50 am
SCL
- SAN
2 stops17h 46m
LATAM Airlines
Deal found 3/12![LATAM Airlines logo]()
$921
This FlightHub deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:20 am
SAN
- SCL
2 stops19h 30m
LATAM Airlines
Fri 4/247:55 pm
SCL
- SAN
2 stops21h 55m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$711
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:18 pm
SAN
- SCL
1 stop19h 05m
Copa Airlines
Thu 4/2312:09 am
SCL
- SAN
1 stop21h 21m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$743
This LATAM Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:20 am
SAN
- SCL
2 stops20h 05m
LATAM Airlines
Tue 4/2811:05 pm
SCL
- SAN
2 stops22h 34m
LATAM Airlines
Deal found 3/7![LATAM Airlines logo]()
$755
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:15 am
SAN
- SCL
3 stops28h 10m
LATAM Airlines
Sun 4/2611:05 pm
SCL
- SAN
2 stops22h 34m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$760
One-way flights from San Diego to SantiagoSearch for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This Trip.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/267:20 am
SAN
- SCL
3 stops34h 45m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/109:28 pm
SAN
- SCL
3 stops46h 15m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$357
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/242:08 pm
SAN
- SCL
3 stops57h 09m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$370
This eDestinos deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:15 am
SAN
- SCL
2 stops20h 10m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$398
This eDestinos deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/312:08 pm
SAN
- SCL
3 stops44h 27m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:47 pm
SAN
- SCL
3 stops43h 48m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$407
This eDestinos deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:55 am
SAN
- SCL
3 stops51h 40m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$409
Find flight deals from San Diego to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $711 (FlightHub) |
One-way from | $357 (Kiwi.com) |
Popular in | December |
Cheapest in | August |
Average price | $941 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 4/22
9:18 pm-11:26 pm
1 stop23h 08m
Santiago Arturo Merino Benitez
Tue 4/28
2:30 am-6:30 pm
1 stop19h 00m
$743
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 4/15
9:18 pm-7:23 pm
1 stop19h 05m
Santiago Arturo Merino Benitez
Thu 4/23
12:09 am-6:30 pm
1 stop21h 21m
$743
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Tue 4/21
6:20 am-10:04 am
3 stops24h 44m
Santiago Arturo Merino Benitez
Tue 4/28
11:05 pm-6:39 pm
2 stops22h 34m
$755
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Thu 4/23
6:15 am-1:25 pm
3 stops28h 10m
Santiago Arturo Merino Benitez
Sun 4/26
8:40 pm-9:49 am
1 stop16h 09m
$760
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Sun 4/5
9:18 pm-10:43 pm
1 stop22h 25m
Santiago Arturo Merino Benitez
Sun 4/12
4:17 am-6:30 pm
1 stop17h 13m
$763
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 4/6
10:40 am-1:45 pm
2 stops24h 05m
Santiago Arturo Merino Benitez
Mon 4/13
8:30 am-1:00 pm
3 stops31h 30m
$785
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 7/22
2:00 pm-4:35 pm
2 stops23h 35m
Santiago Arturo Merino Benitez
Sat 8/8
11:25 pm-6:54 pm
1 stop22h 29m
$875
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Fri 4/24
9:18 pm-7:23 pm
1 stop19h 05m
Santiago Arturo Merino Benitez
Thu 4/30
2:22 am-6:30 pm
1 stop19h 08m
$896
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Mon 4/6
6:15 am-7:15 am
1 stop22h 00m
Santiago Arturo Merino Benitez
Mon 4/13
7:55 pm-4:38 pm
2 stops23h 43m
$906
Quickest round-trip
San DiegoSantiago
SAN - SCL
SANSCL
San Diego
Wed 4/8
9:18 pm-7:23 pm
1 stop19h 05m
Santiago Arturo Merino Benitez
Wed 4/15
4:17 am-6:30 pm
1 stop17h 13m
$916
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from San Diego to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars |
- Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Diego to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
SAN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Diego to Santiago
How far ahead should I book a flight from San Diego to Santiago?
Use this chart to determine the optimal time to book a round-trip flight from San Diego to Santiago. Price data was last updated on March 6, 2026.
Booking 60 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $484). Flying from San Diego to Santiago in May is currently the most expensive (average of $1,013). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Diego to Santiago?
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 12, 2026.
See what other customers who have flown with Delta,Copa Airlines, andLATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
Crew
8.5
Comfort
7.9
Overall
7.9
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
10.0
ExcellentAaron,Oct 2024
LAX - LHR
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San Diego and Santiago flights
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Top 5 airlines flying from San Diego to Santiago
Discover the top 5 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$453 | Average$550 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$507 | Average$953 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$563 | Average$923 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$574 | Average$734 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$642 | Average$993 | FlexibilityNo cancel fee | On-timeN/A |