Santiago

$257+ Cheap flights from San Diego (SAN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/28. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Nov 26 — Dec 31
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Find cheap flights from San Diego to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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Cheapflights Tip: The best prices from San Diego to Santiago Arturo Merino Benitez are usually found in August or October, booked 43 days in advance, depart on a Sunday or Saturday and return on a Friday

Find flight deals from San Diego to Santiago

Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This Copa Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/38:10 pmSAN - SCL
1 stop22h 56mCopa Airlines
Tue 11/183:23 amSCL - SAN
1 stop18h 40mCopa Airlines
Deal found 10/27$557
This LATAM Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/179:59 amSAN - SCL
1 stop15h 01mLATAM Airlines
Thu 11/2711:35 pmSCL - SAN
1 stop14h 40mLATAM Airlines
Deal found 10/25$563
This LATAM Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/99:59 amSAN - SCL
1 stop14h 36mLATAM Airlines
Tue 12/169:30 pmSCL - SAN
1 stop20h 32mLATAM Airlines
Deal found 10/25$566
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/112:18 pmSAN - SCL
2 stops16h 37mAmerican Airlines
Fri 11/710:25 pmSCL - SAN
2 stops18h 35mAmerican Airlines
Deal found 10/27$567
This LATAM Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/269:59 amSAN - SCL
1 stop15h 31mLATAM Airlines
Tue 12/98:15 amSCL - SAN
2 stops20h 20mLATAM Airlines
Deal found 10/25$573
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2810:20 amSAN - SCL
1 stop17h 30mUnited Airlines
Tue 11/410:45 pmSCL - SAN
1 stop17h 16mUnited Airlines
Deal found 10/27$574
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/311:02 amSAN - SCL
2 stops16h 48mUnited Airlines
Wed 11/1910:45 pmSCL - SAN
2 stops21h 15mUnited Airlines
Deal found 10/27$579
This Delta deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/17:59 pmSAN - SCL
1 stop28h 36mDelta
Thu 12/411:55 pmSCL - SAN
1 stop14h 21mDelta
Deal found 10/26$580
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/15:55 pmSAN - SCL
3 stops34h 55mUnited Airlines
Fri 11/710:45 pmSCL - SAN
1 stop17h 16mUnited Airlines
Deal found 10/25$619

Cheap flight deals from San Diego to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$562
(Copa Airlines)

One-way from

$257
(FlightHub)

Popular in

June

Cheapest in

August

Average price

$683
Provider with most accurate pricing for San Diego-Santiago Arturo Merino Benitez flight deals.
Provider most trusted by Cheapflights users for San Diego-Santiago Arturo Merino Benitez flights.
From San Diego to Santiago Arturo Merino Benitez
One-way flight from San Diego to Santiago Arturo Merino Benitez
Highest demand for flights based on searches. 14% potential increase in price ($155 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($22 potential savings vs. average RT price).
Average for round-trip flights in October 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

San Diego

Fly to

Santiago

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 11/26

8:10 pm-8:21 pm

1 stop19h 11m

Santiago Arturo Merino Benitez

Mon 12/8

3:23 am-5:37 pm

1 stop19h 14m

$562

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 11/19

7:00 am-6:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Tue 12/2

8:15 am-10:54 pm

2 stops19h 39m

$574

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 12/1

10:47 am-8:00 am

1 stop16h 13m

Santiago Arturo Merino Benitez

Thu 12/4

11:15 pm-2:32 pm

1 stop20h 17m

$574

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 11/18

6:24 am-5:50 am

2 stops18h 26m

Santiago Arturo Merino Benitez

Thu 11/27

11:10 pm-3:31 pm

1 stop21h 21m

$574

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 11/26

4:07 pm-3:30 pm

2 stops18h 23m

Santiago Arturo Merino Benitez

Tue 12/9

8:15 am-11:35 pm

2 stops20h 20m

$574

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 11/14

12:07 pm-8:50 am

1 stop15h 43m

Santiago Arturo Merino Benitez

Sun 11/23

10:45 pm-11:44 pm

2 stops29h 59m

$579

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Sat 2/28

10:40 pm-7:00 am

1 stop27h 20m

Santiago Arturo Merino Benitez

Sat 3/7

8:20 am-11:11 pm

2 stops19h 51m

$579

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 12/1

7:59 pm-5:35 am

1 stop28h 36m

Santiago Arturo Merino Benitez

Thu 12/4

11:55 pm-9:16 am

1 stop14h 21m

$580

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Fri 11/28

6:35 am-6:30 am

1 stop18h 55m

$257

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 11/12

6:35 am-5:50 am

2 stops18h 15m

$265

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/25

Showing 1-10 of 16 results
1
2

Compare providers for flights from San Diego to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in October.
ProviderPrice AccuracyTrust Score*
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Santiago. Price data was last updated on October 24, 2025.

Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Santiago?

Currently, September is the cheapest month in which you can book a flight from San Diego to Santiago (average of $505). Flying from San Diego to Santiago in July is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SCL?

Find hourly flight availability from San Diego to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

When flying from San Diego to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 17% versus a flight in the afternoon.

How much does it cost to fly round-trip from San Diego to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 27, 2025.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from San Diego to Santiago?

    Copa Airlines and Delta can get you from San Diego to Santiago in just under 18h 55m. Your travel time can differ by up to 16m. The distance from San Diego to Santiago is about 5471 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Diego to Santiago round-trip?

    Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $453 on this airline. Additional options worth looking into are LATAM Airlines and American Airlines, starting at $507 and $563 round-trip. You may be able to fly from San Diego to Santiago for 51% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from San Diego to Santiago one-way?

    One-way options have recently been found by users for as low as $257 on LATAM Airlines. Other airlines that offer cheap prices include Delta from $265 and Copa Airlines from $265 one-way.

  • Can I find deals for flights from San Diego to Santiago that include hotel bookings?

    Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.

  • Can I find deals for business class flights from San Diego to Santiago?

    Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Santiago?

    Currently, September is the cheapest month in which you can book a flight from San Diego to Santiago (average of $505). Flying from San Diego to Santiago in July is currently the most expensive (average of $1,002). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 5 airlines flying from San Diego to Santiago

Discover the top 5 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$453Average$742FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$507Average$966FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$563Average$1,028FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$574Average$922FlexibilityNo cancel feeOn-time69%
DeltaCheapest$802Average$988FlexibilityNo cancel feeOn-timeN/A

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