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$306+ Cheap flights from San Diego (SAN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/7. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — SCL
Feb 25 — Mar 41
Wed 2/25
Wed 3/4
1 adult, Economy
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Cheap flight deals from San Diego to Santiago

Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 26, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/36:30 am
SAN
-
SCL
1 stop20h 10m
Multiple Airlines
Thu 3/54:20 am
SCL
-
SAN
3 stops45h 13m
Multiple Airlines
Deal found 1/25$701
This Copa Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/169:18 pm
SAN
-
SCL
1 stop23h 16m
Copa Airlines
Tue 3/311:46 am
SCL
-
SAN
1 stop20h 44m
Copa Airlines
Deal found 1/25$713
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/162:09 pm
SAN
-
SCL
2 stops27h 46m
Delta
Fri 4/311:55 pm
SCL
-
SAN
1 stop24h 53m
Delta
Deal found 1/25$725
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:15 am
SAN
-
SCL
2 stops20h 45m
Delta
Fri 4/311:55 pm
SCL
-
SAN
1 stop24h 53m
Delta
Deal found 1/25$730
This FlightHub deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:00 am
SAN
-
SCL
1 stop16h 35m
LATAM Airlines
Mon 8/315:40 am
SCL
-
SAN
2 stops20h 15m
LATAM Airlines
Deal found 1/25$737
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:10 am
SAN
-
SCL
1 stop19h 50m
American Airlines
Fri 3/2010:15 pm
SCL
-
SAN
1 stop28h 08m
American Airlines
Deal found 1/26$766
This FlightHub deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:00 pm
SAN
-
SCL
1 stop14h 15m
LATAM Airlines
Wed 10/147:45 am
SCL
-
SAN
2 stops19h 10m
LATAM Airlines
Deal found 1/25$771
This Ovago deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:15 am
SAN
-
SCL
1 stop22h 00m
LATAM Airlines
Mon 4/138:40 pm
SCL
-
SAN
1 stop29h 30m
LATAM Airlines
Deal found 1/24$772
This LATAM Airlines deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2010:30 pm
SAN
-
SCL
2 stops29h 25m
LATAM Airlines
Thu 4/235:00 am
SCL
-
SAN
2 stops42h 47m
LATAM Airlines
Deal found 1/24$775

Find flight deals from San Diego to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 26, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$701
(Kiwi.com)

One-way from

$311
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$983
Provider with most accurate pricing for San Diego-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Diego-Santiago Arturo Merino Benitez flights.
Search Deals
From San Diego to Santiago Arturo Merino Benitez
Search Deals
One-way flight from San Diego to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($22 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

San Diego

Fly to

Santiago

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 3/16

9:18 pm-12:34 am

1 stop23h 16m

Santiago Arturo Merino Benitez

Tue 3/31

1:46 am-6:30 pm

1 stop20h 44m

$713

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/18

10:00 am-5:35 am

1 stop15h 35m

Santiago Arturo Merino Benitez

Fri 4/3

11:55 pm-8:48 pm

1 stop24h 53m

$725

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 3/19

8:00 am-7:40 am

1 stop19h 40m

Santiago Arturo Merino Benitez

Wed 4/1

11:55 pm-8:51 pm

1 stop24h 56m

$725

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 3/16

10:00 am-5:35 am

1 stop15h 35m

Santiago Arturo Merino Benitez

Fri 4/3

11:55 pm-8:48 pm

1 stop24h 53m

$725

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/18

7:00 am-5:55 am

1 stop18h 55m

Santiago Arturo Merino Benitez

Wed 4/1

11:55 pm-8:51 pm

1 stop24h 56m

$725

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 3/17

6:15 am-7:40 am

1 stop21h 25m

Santiago Arturo Merino Benitez

Wed 4/1

11:55 pm-12:01 am

1 stop28h 06m

$725

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Wed 3/18

6:15 am-5:55 am

2 stops19h 40m

Santiago Arturo Merino Benitez

Tue 3/31

11:00 pm-4:31 pm

2 stops21h 31m

$730

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Mon 3/16

8:00 am-7:40 am

1 stop19h 40m

Santiago Arturo Merino Benitez

Sun 3/29

11:00 pm-8:36 pm

2 stops25h 36m

$730

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Thu 3/19

6:15 am-7:40 am

1 stop21h 25m

Santiago Arturo Merino Benitez

Sun 3/29

11:00 pm-8:36 pm

2 stops25h 36m

$730

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

Tue 3/17

6:15 am-7:00 am

2 stops20h 45m

Santiago Arturo Merino Benitez

Fri 4/3

11:55 pm-8:48 pm

1 stop24h 53m

$730

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 18 results
1
2

Compare providers for flights from San Diego to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in January.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Santiago. Price data was last updated on January 23, 2026.

Booking 60 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $495). Flying from San Diego to Santiago in July is currently the most expensive (average of $937). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 26, 2026.
See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
7.9
Good
8,113 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,558 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
LATAM Airlines
7.5
Good
1,912 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
9,198 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
11,189 reviews
Delta
7.9
Good
8,113 reviews

Comfort

7.9

Food

7.2

Boarding

8.1

Crew

8.5

Entertainment

7.8

Overall

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Diego to Santiago?

    United Airlines, Copa Airlines, and Delta can get you from San Diego to Santiago in just under 19h 40m. Your travel time can differ by up to 3h 36m. The distance from San Diego to Santiago is about 5471 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Diego to Santiago round-trip?

    Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $453 on this airline. Additional options worth looking into are LATAM Airlines and American Airlines, starting at $507 and $563 round-trip. You may be able to fly from San Diego to Santiago for 51% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Diego to Santiago that include hotel bookings?

    Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.

  • Can I find deals for business class flights from San Diego to Santiago?

    Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Santiago?

    Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $495). Flying from San Diego to Santiago in July is currently the most expensive (average of $937). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Diego to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from San Diego to Santiago

Discover the top 5 airlines that operate flights from San Diego to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 26, 2026.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$453Average$570FlexibilityNo cancel feeOn-time70%
LATAM AirlinesCheapest$507Average$907FlexibilityNo cancel feeOn-time81%
American AirlinesCheapest$563Average$893FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$574Average$734FlexibilityNo cancel feeOn-time69%
DeltaCheapest$642Average$993FlexibilityNo cancel feeOn-timeN/A

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