How long is the flight from San Diego to Santiago?

United Airlines and Copa Airlines can get you from San Diego to Santiago in just under 17h 24m. Your travel time can differ by up to 1h 40m. The distance from San Diego to Santiago is about 5471 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from San Diego to Santiago round-trip?

Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $453 on this airline. Additional options worth looking into are LATAM Airlines and American Airlines, starting at $507 and $563 round-trip. You may be able to fly from San Diego to Santiago for 52% less than the average price by searching for these airlines.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What are the most popular airlines that fly from San Diego to Santiago?

LATAM Airlines, American Airlines and Delta are the most popular airlines when flying from San Diego to Santiago.

Most accurate provider : When it comes to deals on San Diego-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on San Diego-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from San Diego to Santiago that include hotel bookings?

Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from San Diego to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.

Can I find deals for business class flights from San Diego to Santiago?

Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$306+ Flights from San Diego to Santiago

Q: How much does it cost to fly round-trip from San Diego to Santiago?

Airfare is below average for this route at the moment. San Diego to Santiago flights typically cost between $856 and $1,729 in March. The cheapest round-trip price found within the last 3 days was $668 on LATAM Airlines (Mar 9-Mar 11).

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Find cheap flights from San Diego to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from San Diego to Santiago Arturo Merino Benitez are usually found in November or August, booked 60 days in advance, depart on a Sunday or Saturday and return on a Friday

Cheap flight deals from San Diego to Santiago

Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

dom. 12/286:15 amSAN - SCL

1 stop20h 25mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/10

$743

vie. 12/2610:30 pmSAN - SCL

1 stop26h 40mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/10

$748

mié. 12/245:03 pmSAN - SCL

2 stops19h 27mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/10

$822

vie. 12/266:55 pmSAN - SCL

2 stops32h 55mUnited Airlines

lun. 1/1910:45 pmSCL - SAN

2 stops27h 04mUnited Airlines

Deal found 12/12

$886

vie. 12/2610:30 pmSAN - SCL

1 stop26h 40mLATAM Airlines

lun. 1/1910:15 pmSCL - SAN

2 stops30h 33mLATAM Airlines

Deal found 12/11

$895

mié. 12/2410:30 pmSAN - SCL

2 stops26h 05mLATAM Airlines

lun. 1/1910:15 pmSCL - SAN

2 stops29h 32mLATAM Airlines

Deal found 12/11

$899

mié. 12/2410:30 pmSAN - SCL

2 stops26h 05mLATAM Airlines

lun. 12/2911:10 pmSCL - SAN

1 stop24h 28mLATAM Airlines

Deal found 12/11

$949

jue. 12/256:15 amSAN - SCL

2 stops19h 20mDelta

lun. 12/2911:10 pmSCL - SAN

1 stop26h 50mDelta

Deal found 12/11

$963

Best flights from San Diego to Santiago
Discover carefully curated flight deals from San Diego to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated diciembre 12, 2025.

lun. 1/1910:26 amSAN - SCL

1 stop17h 24mUnited Airlines

vie. 1/2310:45 pmSCL - SAN

2 stops23h 43mUnited Airlines

Deal found 12/10

$669

sáb. 3/2110:30 pmSAN - SCL

1 stop29h 10mMultiple Airlines

vie. 3/274:35 amSCL - SAN

2 stops33h 12mMultiple Airlines

Deal found 12/11

$680

dom. 1/258:16 pmSAN - SCL

1 stop19h 04mCopa Airlines

dom. 2/15:44 amSCL - SAN

1 stop16h 29mCopa Airlines

Deal found 12/11

$692

lun. 3/306:21 amSAN - SCL

1 stop19h 14mLATAM Airlines

jue. 4/308:40 pmSCL - SAN

1 stop24h 58mLATAM Airlines

Deal found 12/11

$707

dom. 12/286:15 amSAN - SCL

1 stop20h 25mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/10

$743

sáb. 1/249:21 amSAN - SCL

2 stops18h 39mAmerican Airlines

sáb. 1/3110:30 pmSCL - SAN

1 stop15h 02mAmerican Airlines

Deal found 12/9

$747

lun. 1/198:16 pmSAN - SCL

1 stop19h 04mCopa Airlines

vie. 1/235:44 amSCL - SAN

1 stop16h 57mCopa Airlines

Deal found 12/10

$692

sáb. 2/2810:37 amSAN - SCL

1 stop13h 58mLATAM Airlines

sáb. 3/711:55 pmSCL - SAN

1 stop18h 57mLATAM Airlines

Deal found 12/11

$742

vie. 12/2610:30 pmSAN - SCL

1 stop26h 40mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/11

$748

Last-minute flights from San Diego to Santiago
Discover last-minute flight deals from San Diego to Santiago. Data last updated diciembre 12, 2025 and is based on user searches.

mié. 12/245:03 pmSAN - SCL

2 stops19h 27mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/10

$822

vie. 12/2610:30 pmSAN - SCL

1 stop26h 40mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/10

$748

vie. 12/266:55 pmSAN - SCL

2 stops32h 55mUnited Airlines

lun. 1/1910:45 pmSCL - SAN

2 stops27h 04mUnited Airlines

Deal found 12/12

$886

vie. 12/2610:30 pmSAN - SCL

1 stop26h 40mLATAM Airlines

lun. 1/1910:15 pmSCL - SAN

2 stops30h 33mLATAM Airlines

Deal found 12/11

$895

dom. 12/286:15 amSAN - SCL

1 stop20h 25mDelta

lun. 1/1911:10 pmSCL - SAN

1 stop26h 27mDelta

Deal found 12/10

$743

jue. 1/84:00 pmSAN - SCL

2 stops35h 50mUnited Airlines

jue. 1/1510:45 pmSCL - SAN

2 stops38h 52mUnited Airlines

Deal found 12/10

$893

lun. 1/196:15 amSAN - SCL

2 stops21h 35mUnited Airlines

vie. 1/2310:45 pmSCL - SAN

2 stops21h 19mUnited Airlines

Deal found 12/10

$669

lun. 1/198:16 pmSAN - SCL

1 stop19h 04mCopa Airlines

vie. 1/235:44 amSCL - SAN

1 stop16h 57mCopa Airlines

Deal found 12/10

$692

sáb. 1/241:19 pmSAN - SCL

1 stop13h 56mAmerican Airlines

sáb. 1/3110:30 pmSCL - SAN

1 stop15h 02mAmerican Airlines

Deal found 12/9

$742

sáb. 1/2411:10 amSAN - SCL

2 stops16h 40mUnited Airlines

sáb. 1/3110:45 pmSCL - SAN

2 stops39h 35mUnited Airlines

Deal found 12/9

$765

One-way flights from San Diego to Santiago
Search for one-way flight options from San Diego to Santiago. Find affordable one-way fares based on user searches. Data last updated diciembre 12, 2025.

jue. 1/18:00 amSAN - SCL

1 stop18h 40mLATAM Airlines

Deal found 12/10

$306

mar. 2/38:05 amSAN - SCL

1 stop18h 35mLATAM Airlines

Deal found 12/10

$311

mar. 2/39:00 amSAN - SCL

2 stops18h 50mUnited Airlines

Deal found 12/10

$313

jue. 1/16:25 amSAN - SCL

3 stops36h 15mMultiple Airlines

Deal found 12/10

$379

mar. 2/38:59 pmSAN - SCL

3 stops29h 41mMultiple Airlines

Deal found 12/10

$411

dom. 3/159:18 pmSAN - SCL

1 stop23h 16mCopa Airlines

Deal found 12/11

$949

sáb. 12/209:45 pmSAN - SCL

1 stop28h 55mDelta

Deal found 12/10

$1,169

sáb. 12/2010:30 pmSAN - SCL

2 stops27h 05mLATAM Airlines

Deal found 12/11

$1,338

Find flight deals from San Diego to Santiago

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$664 (Delta)
One-way from	$306 (SmartFares)
Popular in	December
Cheapest in	November
Average price	$1,243

Provider with most accurate pricing for San Diego-Santiago Arturo Merino Benitez flight deals.

Search Deals

Provider most trusted by Cheapflights users for San Diego-Santiago Arturo Merino Benitez flights.

Search Deals

From San Diego to Santiago Arturo Merino Benitez

Search Deals

One-way flight from San Diego to Santiago Arturo Merino Benitez

Search Deals

High demand for flights, 0% potential price rise

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($27 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

lun. 1/19

10:26 am-8:50 am

1 stop17h 24m

Santiago Arturo Merino Benitez

vie. 1/23

10:45 pm-5:28 pm

2 stops23h 43m

$669

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

sáb. 3/21

10:30 pm-7:40 am

1 stop29h 10m

Santiago Arturo Merino Benitez

vie. 3/27

4:35 am-9:47 am

2 stops33h 12m

$680

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

dom. 1/25

8:16 pm-8:20 pm

1 stop19h 04m

Santiago Arturo Merino Benitez

dom. 2/1

5:44 am-5:13 pm

1 stop16h 29m

$692

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

lun. 1/19

8:16 pm-8:20 pm

1 stop19h 04m

Santiago Arturo Merino Benitez

vie. 1/23

5:44 am-5:41 pm

1 stop16h 57m

$692

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

lun. 3/30

6:21 am-5:35 am

1 stop19h 14m

Santiago Arturo Merino Benitez

jue. 4/30

8:40 pm-6:38 pm

1 stop24h 58m

$707

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

sáb. 2/28

10:37 am-5:35 am

1 stop13h 58m

Santiago Arturo Merino Benitez

sáb. 3/7

11:55 pm-1:52 pm

1 stop18h 57m

$742

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

dom. 12/28

6:15 am-7:40 am

1 stop20h 25m

Santiago Arturo Merino Benitez

lun. 1/19

11:10 pm-8:37 pm

1 stop26h 27m

$743

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

sáb. 1/24

9:21 am-9:00 am

2 stops18h 39m

Santiago Arturo Merino Benitez

sáb. 1/31

10:30 pm-8:32 am

1 stop15h 02m

$747

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

vie. 12/26

10:30 pm-6:10 am

1 stop26h 40m

Santiago Arturo Merino Benitez

lun. 1/19

11:10 pm-8:37 pm

1 stop26h 27m

$748

San DiegoSantiago

SAN - SCL

SANSCL

San Diego

jue. 1/1

6:15 am-5:35 am

2 stops18h 20m

$313

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 17 results

Compare providers for flights from San Diego to Santiago

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in December.

Provider	Price Accuracy	Trust Score*
AranGrant	Price Accuracy2 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
Cheapfaremart	Price Accuracy-	Trust Score*1 star
Ovago	Price Accuracy2 stars	Trust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on San Diego-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Diego-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Diego-Santiago flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on San Diego-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Diego-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

Booking 60 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Diego to Santiago. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Diego to Santiago?

Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $484). Flying from San Diego to Santiago in July is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to SCL?

When flying from San Diego to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 17% versus a flight in the afternoon.

How much does it cost to fly round-trip from San Diego to Santiago?

Reviews of airlines servicing Santiago

See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Delta

7.9

Good

8,007 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Copa Airlines

7.6

Good

1,558 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

LATAM Airlines

7.5

Good

1,887 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

United Airlines

7.4

Good

9,094 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

American Airlines

7.2

Good

11,049 reviews

Delta

7.9

Good

8,007 reviews

Reviews

1 / 20

10.0

Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

How long is the flight from San Diego to Santiago?
United Airlines and Copa Airlines can get you from San Diego to Santiago in just under 17h 24m. Your travel time can differ by up to 1h 40m. The distance from San Diego to Santiago is about 5471 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from San Diego to Santiago round-trip?
Our cheapest airline available from San Diego to Santiago is Copa Airlines. Our recent data shows that you can find tickets from as low as $453 on this airline. Additional options worth looking into are LATAM Airlines and American Airlines, starting at $507 and $563 round-trip. You may be able to fly from San Diego to Santiago for 52% less than the average price by searching for these airlines.
Can I find deals for flights from San Diego to Santiago that include hotel bookings?
Yes. In addition to deals on San Diego to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from San Diego to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Santiago.
Can I find deals for business class flights from San Diego to Santiago?
Yes. Cheapflights offers flight deals from San Diego to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from San Diego to Santiago?
Currently, April is the cheapest month in which you can book a flight from San Diego to Santiago (average of $484). Flying from San Diego to Santiago in July is currently the most expensive (average of $1,008). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Other flights to Santiago

Top 5 airlines flying from San Diego to Santiago

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	Cheapest$453	Average$712	FlexibilityNo cancel fee	On-time70%
LATAM Airlines	Cheapest$507	Average$950	FlexibilityNo cancel fee	On-time81%
American Airlines	Cheapest$563	Average$941	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$574	Average$883	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$642	Average$1,011	FlexibilityNo cancel fee	On-timeN/A

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$306+ Cheap flights from San Diego (SAN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from San Diego to Santiago with Cheapflights

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3. Compare prices and book

Cheapflights Tip: The best prices from San Diego to Santiago Arturo Merino Benitez are usually found in November or August, booked 60 days in advance, depart on a Sunday or Saturday and return on a Friday

Cheap flight deals from San Diego to Santiago

Cheapest flights from San Diego to SantiagoExplore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

Find flight deals from San Diego to Santiago

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from San Diego to Santiago that are best for you.

Compare providers for flights from San Diego to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Diego to Santiago in December.

Best time to book a flight from San Diego to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from San Diego with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Santiago

How far ahead should I book a flight from San Diego to Santiago?

What is the cheapest month to book a flight from San Diego to Santiago?

What is the cheapest time of day to fly from SAN to SCL?

How much does it cost to fly round-trip from San Diego to Santiago?

Reviews of airlines servicing Santiago

See what other customers who have flown with Delta, Copa Airlines, and LATAM Airlines from San Diego to Santiago have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from San Diego to Santiago?

What are the cheapest airlines flying from San Diego to Santiago round-trip?

Can I find deals for flights from San Diego to Santiago that include hotel bookings?

How can I find direct flights from San Diego to Santiago?

Can I find deals for business class flights from San Diego to Santiago?

What is the cheapest month to book a flight from San Diego to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Diego to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from San Diego to Santiago

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Cheapest flights from San Diego to Santiago
Explore the most affordable flight options available from San Diego to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.