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$341+ Cheap flights from Pittsburgh (PIT) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.
PIT — SCL
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheap flight deals from Pittsburgh to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Pittsburgh (PIT) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$668
(Avianca Connect)

One-way from

$341
(Kiwi.com)

Popular in

May

Cheapest in

January

Average price

$884
From Pittsburgh to Santiago Arturo Merino Benitez
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One-way flight from Pittsburgh to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 14% potential increase in price ($175 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($38 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Pittsburgh to Santiago

Cheapest flights from Pittsburgh to Santiago
Explore the most affordable flight options available from Pittsburgh to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Avianca Connect deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:12 amPIT - SCL
2 stops21h 03mMultiple Airlines
Wed 10/1512:55 amSCL - PIT
2 stops23h 21mMultiple Airlines
Deal found 9/9$668
This LATAM Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:53 pmPIT - SCL
2 stops18h 07mLATAM Airlines
Thu 10/169:40 pmSCL - PIT
1 stop13h 54mLATAM Airlines
Deal found 9/9$782
This Mytrip deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/157:10 amPIT - SCL
3 stops30h 35mMultiple Airlines
Mon 9/223:30 pmSCL - PIT
3 stops32h 53mMultiple Airlines
Deal found 9/9$875

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pittsburgh to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Pittsburgh to Santiago that are best for you.

Fly from

Pittsburgh

Fly to

Santiago

Route

Depart

Return

Price

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Tue 3/3

5:55 pm-12:15 pm

1 stop16h 20m

Santiago Arturo Merino Benitez

Tue 3/10

7:55 pm-5:14 pm

1 stop22h 19m

$697

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Thu 10/9

11:39 am-6:45 am

2 stops18h 06m

Santiago Arturo Merino Benitez

Thu 10/16

8:15 am-12:32 am

2 stops17h 17m

$782

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Tue 3/3

12:00 pm-8:50 am

2 stops18h 50m

Santiago Arturo Merino Benitez

Tue 3/10

9:45 pm-1:59 pm

2 stops17h 14m

$794

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Tue 3/3

11:49 am-6:55 am

1 stop17h 06m

Santiago Arturo Merino Benitez

Mon 3/9

12:25 am-6:38 pm

2 stops19h 13m

$803

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Tue 3/3

1:50 pm-7:00 am

1 stop15h 10m

Santiago Arturo Merino Benitez

Mon 3/9

12:25 am-6:38 pm

2 stops19h 13m

$804

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Thu 10/9

4:09 pm-4:17 am

3 stops35h 08m

Santiago Arturo Merino Benitez

Wed 10/15

12:55 am-11:16 pm

3 stops23h 21m

$825

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Sat 11/1

6:51 pm-3:20 pm

3 stops43h 29m

$341

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Sat 11/1

11:50 am-5:55 am

1 stop17h 05m

$529

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Sat 11/1

4:39 pm-7:50 am

1 stop14h 11m

$583

PittsburghSantiago

PIT - SCL

PITSCL

Pittsburgh

Sun 10/19

7:53 pm-1:55 pm

2 stops17h 02m

$2,423

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 11 results
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Best time to book a flight from Pittsburgh to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Pittsburgh with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pittsburgh to Santiago

What is the cheapest time of day to fly from PIT to SCL?

Find hourly flight availability from Pittsburgh to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

One of the essential ways to save on airfare from Pittsburgh to Santiago is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the morning could potentially save you up to 3% on airfare.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, LATAM Airlines, and American Airlines from Pittsburgh to Santiago to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,847 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Pittsburgh to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Pittsburgh to Santiago?

    A quick flight from Pittsburgh to Santiago can take about 16h 20m. Air Canada provides one of the quickest options available for as low as $697. The distance between Pittsburgh and Santiago is about 5137 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Pittsburgh to Santiago round-trip?

    Flying on LATAM Airlines is currently your cheapest option to Santiago, with prices starting at $691. Additional round-trip tickets that might be worth considering are offered by Delta and American Airlines, with the lowest prices starting at $803 and $822, respectively. You may be able to fly from Pittsburgh to Santiago for 31% less than the average price by searching for these airlines.

  • Can I find deals for flights from Pittsburgh to Santiago that include hotel bookings?

    Yes. In addition to deals on Pittsburgh to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pittsburgh to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pittsburgh to Santiago.

  • Can I find deals for business class flights from Pittsburgh to Santiago?

    Yes. Cheapflights offers flight deals from Pittsburgh to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Pittsburgh to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Pittsburgh to Santiago (average of $752). Flying from Pittsburgh to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Pittsburgh to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Pittsburgh to Santiago

Discover the top 3 airlines that operate flights from Pittsburgh to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$691Average$1,053FlexibilityNo cancel feeOn-time81%
DeltaCheapest$803Average$1,138FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$822Average$1,118FlexibilityNo cancel feeOn-time71%

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