HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Santiago

$410+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/17. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
Jan 3 — Jan 101
Sat 1/3
Sat 1/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Minneapolis to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Minneapolis St Paul to Santiago Arturo Merino Benitez are usually found in September or November, booked 61 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from Minneapolis to Santiago

Cheapest flights from Minneapolis to Santiago
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 4, 2025.

This eDestinos deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:09 pmMSP - SCL
3 stops52h 52mMultiple Airlines
Sat 1/1710:35 amSCL - MSP
1 stop15h 52mMultiple Airlines
Deal found 12/3$993
This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/56:18 amMSP - SCL
2 stops22h 57mMultiple Airlines
Sat 12/134:35 amSCL - MSP
2 stops19h 44mMultiple Airlines
Deal found 12/3$1,065
This eDestinos deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2210:09 pmMSP - SCL
3 stops52h 52mMultiple Airlines
Sun 1/1810:15 pmSCL - MSP
3 stops51h 44mMultiple Airlines
Deal found 12/4$1,073
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2910:07 amMSP - SCL
2 stops20h 18mAmerican Airlines
Sat 1/1710:30 pmSCL - MSP
1 stop15h 20mAmerican Airlines
Deal found 12/4$1,089
This American Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/139:59 amMSP - SCL
2 stops18h 46mAmerican Airlines
Sun 12/2811:15 pmSCL - MSP
2 stops21h 51mAmerican Airlines
Deal found 12/4$1,124
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/134:54 pmMSP - SCL
2 stops36h 56mUnited Airlines
Sun 12/2810:45 pmSCL - MSP
2 stops42h 31mUnited Airlines
Deal found 12/4$1,135
This eDestinos deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:42 pmMSP - SCL
3 stops48h 42mMultiple Airlines
Fri 1/1612:35 pmSCL - MSP
2 stops37h 52mMultiple Airlines
Deal found 12/4$1,162

Find flight deals from Minneapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$671
(Mytrip)

One-way from

$410
(Air Canada)

Popular in

December

Cheapest in

September

Average price

$1,348
Provider with most accurate pricing for Minneapolis St Paul-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Santiago Arturo Merino Benitez flights.
Search Deals
From Minneapolis St Paul to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Minneapolis St Paul to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($20 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Fly from

Minneapolis

Fly to

Santiago

Route

Depart

Return

Price

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 1/19

6:12 am-12:15 pm

3 stops27h 03m

Santiago Arturo Merino Benitez

Mon 1/26

12:35 pm-6:55 pm

3 stops33h 20m

$853

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 1/19

2:01 pm-9:00 am

2 stops15h 59m

Santiago Arturo Merino Benitez

Mon 1/26

10:35 pm-2:02 pm

2 stops18h 27m

$919

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Sun 1/18

3:25 pm-8:50 am

2 stops38h 25m

Santiago Arturo Merino Benitez

Sun 1/25

10:45 pm-1:00 pm

1 stop17h 15m

$976

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 2/6

8:00 am-6:00 am

2 stops19h 00m

Santiago Arturo Merino Benitez

Fri 3/13

1:38 am-5:23 pm

2 stops17h 45m

$983

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 12/22

10:09 pm-6:01 am

3 stops52h 52m

Santiago Arturo Merino Benitez

Sat 1/17

10:35 am-11:27 pm

1 stop15h 52m

$993

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 1/5

8:06 am-10:39 am

2 stops23h 33m

Santiago Arturo Merino Benitez

Fri 1/16

6:40 am-3:12 pm

3 stops35h 32m

$1,029

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 1/16

3:06 pm-1:09 am

3 stops31h 03m

Santiago Arturo Merino Benitez

Sat 1/31

3:37 pm-11:29 pm

3 stops34h 52m

$1,137

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Sat 12/20

2:36 pm-5:55 am

2 stops36h 19m

Santiago Arturo Merino Benitez

Fri 1/16

12:35 pm-11:27 pm

2 stops37h 52m

$1,174

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 12/29

6:00 am-7:45 am

1 stop22h 45m

Santiago Arturo Merino Benitez

Sat 1/17

10:30 pm-10:50 am

1 stop15h 20m

$1,254

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 2/6

6:00 am-8:50 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Sat 3/14

9:45 pm-7:47 pm

2 stops24h 02m

$1,254

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/3

Showing 1-10 of 16 results
1
2

Compare providers for flights from Minneapolis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Santiago in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars
CheapfaremartPrice Accuracy-Trust Score*1 star

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Minneapolis-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Minneapolis-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Minneapolis-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Minneapolis-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Minneapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Santiago

How far ahead should I book a flight from Minneapolis to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Minneapolis to Santiago. Price data was last updated on November 28, 2025.

The best time to book flights from Minneapolis to Santiago is 57 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Minneapolis to Santiago?

Currently, September is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $633). Flying from Minneapolis to Santiago in May is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SCL?

Find hourly flight availability from Minneapolis to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 4, 2025.

When flying from Minneapolis to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 34% versus a flight in the morning.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 4, 2025.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,011 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,011 reviews
Delta
7.9
Good
8,011 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,889 reviews
Delta
7.9
Good
8,011 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,063 reviews
Delta
7.9
Good
8,011 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,043 reviews
Delta
7.9
Good
8,011 reviews

Crew

8.5

Food

7.3

Comfort

7.9

Overall

7.9

Boarding

8.1

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Minneapolis to Santiago?

    Departing from Minneapolis to Santiago will take you 15h 59m. The distance between Minneapolis and Santiago is about 5584 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Minneapolis to Santiago round-trip?

    Flying on American Airlines is currently your cheapest option to Santiago, with prices starting at $745. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $853 and $853, respectively. These flights start at 33% lower than the current average price 3 months from now.

  • Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Santiago.

  • Can I find deals for business class flights from Minneapolis to Santiago?

    Yes. Cheapflights offers flight deals from Minneapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Santiago?

    Currently, September is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $633). Flying from Minneapolis to Santiago in May is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Minneapolis to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Fargo to Santiago flights
Minneapolis to Easter Island flights
Sioux Falls to Santiago flights
Minneapolis to Puerto Montt flights

Top 4 airlines flying from Minneapolis to Santiago

Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$745Average$993FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$853Average$1,008FlexibilityNo cancel feeOn-time69%
DeltaCheapest$853Average$1,175FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$892Average$1,111FlexibilityNo cancel feeOn-time81%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.