$405+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Minneapolis to Santiago
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Cheapest flights from Minneapolis to SantiagoExplore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This Mytrip deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:30 pm -
2 stops21h 40m
Sun 11/82:10 am -
3 stops24h 54m
Deal found 9/18![Multiple Airlines logo]()
$861
This Mytrip deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:33 pm -
3 stops29h 02m
Tue 12/19:55 pm -
1 stop20h 55m
Deal found 9/20![Multiple Airlines logo]()
$873
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:19 am -
3 stops26h 51m
Thu 11/127:30 am -
2 stops30h 42m
Deal found 9/21![Multiple Airlines logo]()
$880
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:33 pm -
3 stops29h 02m
Fri 11/67:00 am -
2 stops35h 04m
Deal found 9/17![Multiple Airlines logo]()
$910
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:53 am -
2 stops34h 46m
Sat 10/3111:10 pm -
1 stop18h 42m
Deal found 9/18![Multiple Airlines logo]()
$923
This Air Canada deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:30 pm -
2 stops35h 20m
Thu 12/249:55 pm -
1 stop26h 25m
Deal found 9/21![Air Canada logo]()
$925
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:51 am -
2 stops49h 44m
Sat 10/3111:10 pm -
1 stop18h 42m
Deal found 9/18![Multiple Airlines logo]()
$946
This Trip.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:30 pm -
1 stop16h 45m
Mon 11/99:55 pm -
1 stop26h 25m
Deal found 9/18![Air Canada logo]()
$947
Best flights from Minneapolis to SantiagoDiscover carefully curated flight deals from Minneapolis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Minneapolis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/32:33 pm -
3 stops29h 02m
Sun 11/84:35 pm -
2 stops31h 45m
Deal found 9/17![Multiple Airlines logo]()
$973
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/82:51 pm -
1 stop13h 49m
Thu 12/2411:55 pm -
1 stop20h 30m
Deal found 9/21![Delta logo]()
$1,241
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/911:29 am -
2 stops18h 21m
Tue 12/2910:45 pm -
2 stops22h 22m
Deal found 9/21![United Airlines logo]()
$1,361
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/183:55 pm -
3 stops35h 31m
Thu 10/298:55 pm -
1 stop20h 55m
Deal found 9/19![Multiple Airlines logo]()
$1,087
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/244:30 pm -
2 stops35h 08m
Sat 11/289:25 am -
3 stops31h 50m
Deal found 9/19![Multiple Airlines logo]()
$1,244
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/711:29 am -
2 stops18h 21m
Mon 1/1110:45 pm -
2 stops21h 57m
Deal found 9/21![United Airlines logo]()
$1,403
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:28 pm -
2 stops19h 32m
Fri 12/258:25 pm -
2 stops18h 50m
Deal found 9/21![Delta logo]()
$1,438
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:33 pm -
3 stops30h 03m
Tue 10/67:40 am -
3 stops30h 10m
Deal found 9/17![Multiple Airlines logo]()
$1,276
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/63:14 pm -
2 stops38h 36m
Sun 12/2710:45 pm -
2 stops18h 49m
Deal found 9/21![United Airlines logo]()
$1,462
Last-minute flights from Minneapolis to SantiagoDiscover last-minute flight deals from Minneapolis to Santiago. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to Santiago. Data last updated September 21, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:10 am -
2 stops19h 45m
Thu 10/298:55 pm -
1 stop26h 15m
Deal found 9/19![Multiple Airlines logo]()
$1,070
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:15 am -
2 stops38h 24m
Sat 10/3111:10 pm -
1 stop18h 42m
Deal found 9/18![Multiple Airlines logo]()
$1,073
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:51 am -
2 stops49h 44m
Sat 10/3111:10 pm -
1 stop18h 42m
Deal found 9/18![Multiple Airlines logo]()
$946
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:51 am -
2 stops49h 44m
Mon 11/211:55 pm -
1 stop20h 42m
Deal found 9/18![Multiple Airlines logo]()
$1,072
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:53 am -
2 stops34h 46m
Sat 10/3111:10 pm -
1 stop18h 42m
Deal found 9/18![Multiple Airlines logo]()
$923
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:53 am -
2 stops34h 46m
Mon 11/211:55 pm -
1 stop20h 42m
Deal found 9/18![Multiple Airlines logo]()
$1,049
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2510:53 am -
2 stops34h 46m
Sun 11/111:55 pm -
1 stop26h 54m
Deal found 9/18![Multiple Airlines logo]()
$1,064
This Justfly.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/264:30 pm -
1 stop16h 45m
Sat 10/319:55 pm -
1 stop20h 55m
Deal found 9/18![Air Canada logo]()
$1,011
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2610:51 am -
2 stops31h 28m
Sun 11/111:55 pm -
1 stop26h 54m
Deal found 9/18![Multiple Airlines logo]()
$1,065
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:30 am -
2 stops20h 25m
Sat 10/3111:10 pm -
1 stop18h 42m
Deal found 9/18![Multiple Airlines logo]()
$967
This Air Canada deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2812:00 pm -
1 stop21h 15m
Mon 11/29:55 pm -
1 stop26h 25m
Deal found 9/18![Air Canada logo]()
$1,057
One-way flights from Minneapolis to SantiagoSearch for one-way flight options from Minneapolis to Santiago. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
Search for one-way flight options from Minneapolis to Santiago. Find affordable one-way fares based on user searches. Data last updated September 21, 2026.
This Air Canada deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:30 pm -
2 stops35h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Air Canada logo]()
$405
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/269:30 am -
3 stops43h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$602
This FlightHub deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:45 pm -
3 stops23h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![LATAM Airlines logo]()
$820
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/206:50 pm -
2 stops35h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![United Airlines logo]()
$919
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/209:05 am -
1 stop19h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![LATAM Airlines logo]()
$938
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/207:15 am -
1 stop21h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/20![Delta logo]()
$958
Find flight deals from Minneapolis to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $861 (Mytrip) |
One-way from | $405 (Air Canada) |
Popular in | April |
Cheapest in | February |
Average price | $1,510 |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Wed 12/2
4:30 pm-6:50 am
2 stops35h 20m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$405
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Sat 9/26
9:30 am-6:35 am
3 stops43h 05m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$602
Quickest round-trip
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Wed 12/2
12:45 pm-3:00 pm
3 stops23h 15m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$820
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 11/3
2:33 pm-10:35 pm
3 stops29h 02m
Santiago Arturo Merino Benitez
Sun 11/8
4:35 pm-9:20 pm
2 stops31h 45m
$973
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Sun 10/18
3:55 pm-5:26 am
3 stops35h 31m
Santiago Arturo Merino Benitez
Thu 10/29
8:55 pm-3:50 pm
1 stop20h 55m
$1,087
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 12/8
2:51 pm-7:40 am
1 stop13h 49m
Santiago Arturo Merino Benitez
Thu 12/24
11:55 pm-5:25 pm
1 stop20h 30m
$1,241
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 11/24
4:30 pm-6:38 am
2 stops35h 08m
Santiago Arturo Merino Benitez
Sat 11/28
9:25 am-2:15 pm
3 stops31h 50m
$1,244
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Fri 10/2
2:33 pm-10:36 pm
3 stops30h 03m
Santiago Arturo Merino Benitez
Tue 10/6
7:40 am-11:50 am
3 stops30h 10m
$1,276
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Wed 12/9
11:29 am-8:50 am
2 stops18h 21m
Santiago Arturo Merino Benitez
Tue 12/29
10:45 pm-6:07 pm
2 stops22h 22m
$1,361
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Mon 12/7
11:29 am-8:50 am
2 stops18h 21m
Santiago Arturo Merino Benitez
Mon 1/11
10:45 pm-5:42 pm
2 stops21h 57m
$1,403
Showing 1-10 of 12 resultsSorted by cheapest first
Compare providers for flights from Minneapolis to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Santiago in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Minneapolis-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Minneapolis-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Minneapolis-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Minneapolis-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Minneapolis to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
MSP-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to Santiago
What is the cheapest month to book a flight from Minneapolis to Santiago?
Currently, February is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $954). Flying from Minneapolis to Santiago in April is currently the most expensive (average of $1,570). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Minneapolis to Santiago?
Airfare is below average for this route at the moment.
Minneapolis to Santiago flights typically cost between $1,300 and $1,610 in November.The cheapest round-trip price found within the last 5 days was $861 on Multiple Airlines (Nov 2-Nov 8).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated September 21, 2026.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Food
7.2
Crew
8.5
Comfort
7.8
Boarding
8.1
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Minneapolis to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minneapolis to Santiago by cabin class
Find flights from Minneapolis to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and Santiago flights
Browse other Minneapolis and Santiago flight options. Last updated on September 21, 2026.
Other flights from Minneapolis
Browse through other flights departing from Minneapolis. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Top 4 airlines flying from Minneapolis to Santiago
Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$718 | Average$1,337 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$914 | Average$1,008 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$939 | Average$1,337 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,158 | Average$1,493 | FlexibilityNo cancel fee | On-timeN/A |