$402+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to Santiago with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Minneapolis to Santiago
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Best
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Cheapest flights from Minneapolis to SantiagoExplore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This Gotogate deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:00 pm -
1 stop21h 15m
Thu 12/109:55 pm -
1 stop20h 55m
Deal found 10/15![Air Canada logo]()
$766
This Air Canada deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:30 pm -
1 stop16h 45m
Tue 12/89:55 pm -
1 stop26h 25m
Deal found 10/17![Air Canada logo]()
$775
This Air Canada deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:30 pm -
1 stop16h 45m
Sun 12/68:25 am -
2 stops34h 25m
Deal found 10/15![Air Canada logo]()
$797
This Travelocity deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:00 pm -
1 stop21h 15m
Thu 12/39:55 pm -
1 stop20h 55m
Deal found 10/17![Air Canada logo]()
$802
This Mytrip deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:45 am -
2 stops26h 30m
Mon 12/79:55 pm -
1 stop26h 25m
Deal found 10/18![Multiple Airlines logo]()
$883
This Mytrip deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:10 am -
2 stops20h 35m
Fri 11/62:10 am -
3 stops24h 54m
Deal found 10/14![Multiple Airlines logo]()
$890
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:10 am -
2 stops21h 28m
Thu 12/108:35 pm -
2 stops21h 11m
Deal found 10/15![Multiple Airlines logo]()
$895
Best flights from Minneapolis to SantiagoDiscover carefully curated flight deals from Minneapolis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from Minneapolis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:30 pm -
1 stop16h 45m
Tue 12/89:55 pm -
3 stops29h 28m
Deal found 10/15![Multiple Airlines logo]()
$1,070
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/161:00 pm -
1 stop14h 55m
Thu 3/48:40 am -
2 stops17h 20m
Deal found 10/15![Delta logo]()
$1,292
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2310:56 am -
2 stops20h 04m
Sat 4/39:35 pm -
2 stops22h 01m
Deal found 10/15![American Airlines logo]()
$1,388
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1611:32 am -
2 stops18h 18m
Thu 3/410:45 pm -
2 stops21h 26m
Deal found 10/15![United Airlines logo]()
$1,481
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/26:25 am -
2 stops22h 13m
Sat 4/107:33 pm -
2 stops20h 09m
Deal found 10/15![Multiple Airlines logo]()
$1,269
This Delta deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/171:00 pm -
1 stop14h 55m
Tue 3/28:40 am -
2 stops17h 20m
Deal found 10/15![Delta logo]()
$1,292
This Booking.com deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:30 pm -
2 stops32h 05m
Fri 11/68:35 pm -
2 stops18h 24m
Deal found 10/15![Multiple Airlines logo]()
$1,306
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:00 am -
2 stops20h 25m
Sat 12/510:30 pm -
2 stops18h 17m
Deal found 10/18![American Airlines logo]()
$1,468
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1711:32 am -
2 stops18h 18m
Thu 3/410:45 pm -
2 stops19h 46m
Deal found 10/15![United Airlines logo]()
$1,481
Last-minute flights from Minneapolis to SantiagoDiscover last-minute flight deals from Minneapolis to Santiago. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to Santiago. Data last updated October 19, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/277:10 am -
2 stops20h 35m
Fri 11/62:10 am -
3 stops24h 54m
Deal found 10/14![Multiple Airlines logo]()
$890
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/22:33 pm -
3 stops30h 51m
Fri 11/612:15 pm -
3 stops28h 51m
Deal found 10/15![Multiple Airlines logo]()
$931
This Priceline deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2312:00 pm -
1 stop21h 15m
Sun 11/298:25 am -
2 stops34h 25m
Deal found 10/19![Air Canada logo]()
$901
This Gotogate deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2712:00 pm -
1 stop21h 15m
Thu 12/109:55 pm -
1 stop20h 55m
Deal found 10/15![Air Canada logo]()
$766
This Mytrip deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:10 am -
2 stops21h 28m
Thu 12/108:35 pm -
2 stops21h 11m
Deal found 10/15![Multiple Airlines logo]()
$895
This Air Canada deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates ” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:30 pm -
1 stop16h 45m
Tue 12/89:55 pm -
1 stop26h 25m
Deal found 10/17![Air Canada logo]()
$775
This Air Canada deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/294:30 pm -
1 stop16h 45m
Sun 12/68:25 am -
2 stops34h 25m
Deal found 10/15![Air Canada logo]()
$797
This Travelocity deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2912:00 pm -
1 stop21h 15m
Thu 12/39:55 pm -
1 stop20h 55m
Deal found 10/17![Air Canada logo]()
$802
One-way flights from Minneapolis to SantiagoSearch for one-way flight options from Minneapolis to Santiago. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from Minneapolis to Santiago. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
2 stops18h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/14![Multiple Airlines logo]()
$402
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/295:53 pm -
3 stops49h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Multiple Airlines logo]()
$475
This eDestinos deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/247:55 am -
2 stops40h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$544
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/232:48 pm -
3 stops31h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$573
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/2310:51 am -
2 stops34h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$586
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/2210:00 am -
3 stops36h 13m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$617
This Kiwi.com deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:49 pm -
3 stops51h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/16![Multiple Airlines logo]()
$637
Find flight deals from Minneapolis to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 19, 2026.
Most accurate provider | Ovago 3 stars |
|---|---|
Most trusted provider | Ovago 3 stars |
Round-trip from | $734 (Orbitz) |
One-way from | $402 (Kiwi.com) |
Popular in | July |
Cheapest in | February |
Average price | $1,374 |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 11/17
6:20 am-3:38 am
2 stops18h 18m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$402
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 12/29
5:53 pm-10:35 pm
3 stops49h 42m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$475
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Wed 12/2
2:41 pm-8:15 am
1 stop14h 34m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$865
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 11/17
6:00 am-8:45 am
1 stop23h 45m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$865
Quickest round-trip
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 12/29
2:41 pm-8:00 am
1 stop14h 19m
Santiago Arturo Merino Benitez
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$865
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Mon 11/16
4:30 pm-12:15 pm
1 stop16h 45m
Santiago Arturo Merino Benitez
Tue 12/8
9:55 pm-12:23 am
3 stops29h 28m
$1,070
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Fri 4/2
6:25 am-6:38 am
2 stops22h 13m
Santiago Arturo Merino Benitez
Sat 4/10
7:33 pm-2:42 pm
2 stops20h 09m
$1,269
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Tue 2/16
1:00 pm-6:55 am
1 stop14h 55m
Santiago Arturo Merino Benitez
Thu 3/4
8:40 am-11:00 pm
2 stops17h 20m
$1,292
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Wed 2/17
1:00 pm-6:55 am
1 stop14h 55m
Santiago Arturo Merino Benitez
Tue 3/2
8:40 am-11:00 pm
2 stops17h 20m
$1,292
MinneapolisSantiago
MSP Minneapolis St Paul - SCL Santiago Arturo Merino Benitez
MSPSCL
Minneapolis St Paul
Mon 11/2
4:30 pm-3:35 am
2 stops32h 05m
Santiago Arturo Merino Benitez
Fri 11/6
8:35 pm-11:59 am
2 stops18h 24m
$1,306
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Minneapolis to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Santiago in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Minneapolis-Santiago flights, users find the pricing of Ovago to be most consistent on Cheapflights vs. Ovago Users can find the same prices on Minneapolis-Santiago flight deals on Cheapflights vs. Ovago >95% of the time. Price accuracy is based on data collected from Minneapolis-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Minneapolis-Santiago flights, Cheapflights users trust Ovago the most. Ovago has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Minneapolis to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
MSP-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to Santiago
What is the cheapest month to book a flight from Minneapolis to Santiago?
Currently, February is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $954). Flying from Minneapolis to Santiago in July is currently the most expensive (average of $1,649). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Minneapolis to Santiago?
Airfare is below average for this route at the moment.
Minneapolis to Santiago flights typically cost between $1,320 and $1,800 in March.The cheapest round-trip price found within the last 5 days was $734 on Air Canada (Mar 15-Mar 22).
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated October 19, 2026.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Boarding
8.1
Crew
8.5
Food
7.2
Entertainment
7.8
Comfort
7.8
Overall
7.8
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Minneapolis to Santiago
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minneapolis to Santiago by cabin class
Find flights from Minneapolis to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and Santiago flights
Browse other Minneapolis and Santiago flight options. Last updated on October 19, 2026.
Other flights from Minneapolis
Browse through other flights departing from Minneapolis. Flights are based on user searches made on Cheapflights and were last updated on October 19, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 19, 2026.
Top 4 airlines flying from Minneapolis to Santiago
Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$718 | Average$1,337 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$914 | Average$970 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$1,114 | Average$1,322 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$1,159 | Average$1,360 | FlexibilityNo cancel fee | On-timeN/A |