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$399+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/25. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
May 27 — Jun 31
Wed 5/27
Wed 6/3
1 adult, Economy
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Cheap flight deals from Minneapolis to Santiago

Cheapest flights from Minneapolis to Santiago
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 27, 2026.

This Trip.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:25 am
MSP
-
SCL
2 stops19h 20m
Multiple Airlines
Thu 7/3012:30 am
SCL
-
MSP
2 stops22h 29m
Multiple Airlines
Deal found 4/22$928
This Mytrip deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:40 am
MSP
-
SCL
3 stops28h 50m
Multiple Airlines
Tue 6/304:41 am
SCL
-
MSP
3 stops34h 47m
Multiple Airlines
Deal found 4/22$937
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:10 am
MSP
-
SCL
2 stops30h 35m
Multiple Airlines
Tue 11/107:55 pm
SCL
-
MSP
1 stop22h 54m
Multiple Airlines
Deal found 4/26$946
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:30 am
MSP
-
SCL
3 stops26h 05m
Multiple Airlines
Sat 8/296:40 am
SCL
-
MSP
3 stops32h 26m
Multiple Airlines
Deal found 4/23$986
This Mytrip deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/181:10 pm
MSP
-
SCL
3 stops30h 55m
Multiple Airlines
Tue 9/224:20 pm
SCL
-
MSP
3 stops30h 16m
Multiple Airlines
Deal found 4/25$996
This Mytrip deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:50 am
MSP
-
SCL
3 stops33h 21m
Multiple Airlines
Mon 6/85:00 am
SCL
-
MSP
3 stops35h 13m
Multiple Airlines
Deal found 4/23$1,000
This Mytrip deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2610:30 am
MSP
-
SCL
3 stops26h 00m
Multiple Airlines
Tue 6/26:40 am
SCL
-
MSP
2 stops32h 18m
Multiple Airlines
Deal found 4/26$1,017
This Mytrip deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:05 am
MSP
-
SCL
3 stops30h 25m
Multiple Airlines
Sun 6/2812:30 am
SCL
-
MSP
2 stops22h 18m
Multiple Airlines
Deal found 4/24$1,018

Find flight deals from Minneapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$928
(Trip.com)

One-way from

$399
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$744
Provider with most accurate pricing for Minneapolis St Paul-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Santiago Arturo Merino Benitez flights.
Search Deals
From Minneapolis St Paul to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Minneapolis St Paul to Santiago Arturo Merino Benitez
Search Deals
High demand for flights, 2% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 6/1

6:05 am-1:30 pm

3 stops30h 25m

Santiago Arturo Merino Benitez

Sun 6/28

12:30 am-9:48 pm

2 stops22h 18m

$1,018

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 5/26

6:40 am-7:23 pm

2 stops35h 43m

Santiago Arturo Merino Benitez

Tue 6/2

10:55 pm-1:58 pm

1 stop16h 03m

$1,070

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 8/17

10:22 am-5:03 am

2 stops17h 41m

Santiago Arturo Merino Benitez

Tue 9/8

12:22 pm-11:19 pm

2 stops36h 57m

$1,078

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 7/27

7:35 am-5:03 am

2 stops20h 28m

Santiago Arturo Merino Benitez

Thu 8/6

2:27 am-11:59 pm

2 stops22h 32m

$1,116

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 8/14

7:36 am-5:03 am

2 stops20h 27m

Santiago Arturo Merino Benitez

Tue 9/1

2:27 am-11:19 pm

2 stops21h 52m

$1,128
Quickest round-trip

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 6/15

8:55 am-6:55 am

1 stop21h 00m

Santiago Arturo Merino Benitez

Wed 7/22

10:55 pm-1:50 pm

1 stop15h 55m

$1,177

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 6/15

8:23 pm-10:43 pm

2 stops25h 20m

Santiago Arturo Merino Benitez

Wed 7/22

11:22 am-8:46 am

2 stops22h 24m

$1,178

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 7/13

7:35 am-1:50 am

2 stops17h 15m

Santiago Arturo Merino Benitez

Sun 7/19

2:27 am-9:18 am

2 stops31h 51m

$1,178
Cheapest one-way
Quickest one-way

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 5/25

6:00 am-7:15 am

2 stops24h 15m

$554

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Sorted by cheapest first

Compare providers for flights from Minneapolis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Santiago in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Minneapolis-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Minneapolis-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Minneapolis-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Minneapolis-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Minneapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Santiago

What is the cheapest month to book a flight from Minneapolis to Santiago?

Currently, April is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $744). Flying from Minneapolis to Santiago in December is currently the most expensive (average of $1,348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Minneapolis to Santiago?

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated April 27, 2026.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,460 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,460 reviews
Delta
7.9
Good
8,460 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.4
Good
1,912 reviews
Delta
7.9
Good
8,460 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,664 reviews
Delta
7.9
Good
8,460 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,668 reviews
Delta
7.9
Good
8,460 reviews

Overall

7.9

Crew

8.5

Comfort

7.9

Food

7.2

Boarding

8.1

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Minneapolis to Santiago round-trip?

    Flying on American Airlines is currently your cheapest option to Santiago, with prices starting at $718. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $853 and $853, respectively. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Santiago.

  • Can I find deals for business class flights from Minneapolis to Santiago?

    Yes. Cheapflights offers flight deals from Minneapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $744). Flying from Minneapolis to Santiago in December is currently the most expensive (average of $1,348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Minneapolis to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Sioux Falls to Santiago flights

Top 4 airlines flying from Minneapolis to Santiago

Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$718Average$1,225FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$853Average$973FlexibilityNo cancel feeOn-time69%
DeltaCheapest$853Average$1,268FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$916Average$1,208FlexibilityNo cancel feeOn-time81%

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