How long is the flight from Minneapolis to Santiago?

Departing from Minneapolis to Santiago will take you 23h 50m. The distance between Minneapolis and Santiago is about 5584 mi. Both multi-stop and nonstop flights can be found to your destination and back.

What are the cheapest airlines flying from Minneapolis to Santiago round-trip?

Flying on American Airlines is currently your cheapest option to Santiago, with prices starting at $745. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and Delta, with the lowest prices starting at $815 and $853, respectively. These flights start at 30% lower than the current average price 3 months from now.

What is the cheapest day to fly from Minneapolis to Santiago?

Travelers seeking maximum savings on their Minneapolis to Santiago flight should consider departing on Monday evenings when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

What are the most popular airlines that fly from Minneapolis to Santiago?

Before booking your flight from Minneapolis to Santiago check out the most popular airlines for this route: American Airlines, Delta or LATAM Airlines.

What is the cheapest day to fly round-trip from Minneapolis to Santiago?

Flying to your destination on a Wednesday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to Santiago. Check prices with Cheapflights to find a great deal for your trip.

How far in advance should I book a flight from Minneapolis to Santiago?

To save up to 44% on this flight, we recommend booking at least 58 days prior to travel. The price may fluctuate and will likely increase closer to your departure date. Users on Cheapflights have found tickets from Minneapolis to Santiago from $1,015 1-2 weeks out and tickets from $1,912 for flights departing within the next 72 hours.

What is the cheapest month to fly from Minneapolis to Santiago?

October is one of the best times of the year to fly to Santiago from Minneapolis. Prices for October average $1,071 per person but you can even find prices for as low as $792. The most expensive prices can be found in the month of December. Opting for a October flight can save you 15% on your journey compared to booking in December

Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?

Yes. In addition to deals on Minneapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Minneapolis to Santiago?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Santiago.

Can I find deals for business class flights from Minneapolis to Santiago?

Yes. Cheapflights offers flight deals from Minneapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$395+ Flights from Minneapolis to Santiago

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Minneapolis St Paul to Santiago Arturo Merino Benitez are usually found in October or January, booked 57 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from Minneapolis to Santiago

Round-trip from	$639 (Mytrip)
One-way from	$395 (Air Canada)
Popular in	December
Cheapest in	October
Average price	$1,007

From Minneapolis St Paul to Santiago Arturo Merino Benitez

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One-way flight from Minneapolis St Paul to Santiago Arturo Merino Benitez

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High demand for flights, 2% potential price rise

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Cheapest flight prices on average. 1% potential price decrease ($16 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Minneapolis to Santiago

Cheapest flights from Minneapolis to Santiago
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

Mon 10/206:12 amMSP - SCL

3 stops28h 08mMultiple Airlines

Fri 10/319:05 pmSCL - MSP

3 stops28h 22mMultiple Airlines

Deal found 9/14

$639

Thu 10/306:18 amMSP - SCL

2 stops19h 17mMultiple Airlines

Wed 11/51:35 amSCL - MSP

2 stops23h 14mMultiple Airlines

Deal found 9/15

$758

Wed 11/56:18 amMSP - SCL

3 stops36h 37mMultiple Airlines

Wed 11/121:35 amSCL - MSP

3 stops21h 49mMultiple Airlines

Deal found 9/12

$828

Best flights from Minneapolis to Santiago
Discover carefully curated flight deals from Minneapolis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 15, 2025.

Mon 10/206:12 amMSP - SCL

2 stops30h 33mMultiple Airlines

Fri 10/3112:30 pmSCL - MSP

2 stops28h 30mMultiple Airlines

Deal found 9/14

$641

Fri 2/2012:00 pmMSP - SCL

2 stops40h 00mAir Canada

Fri 2/278:35 amSCL - MSP

2 stops39h 44mAir Canada

Deal found 9/14

$777

Tue 11/116:00 amMSP - SCL

2 stops23h 50mUnited Airlines

Wed 11/1910:45 pmSCL - MSP

1 stop21h 13mUnited Airlines

Deal found 9/15

$914

Mon 10/136:30 amMSP - SCL

1 stop23h 30mAmerican Airlines

Mon 10/209:55 pmSCL - MSP

2 stops21h 21mAmerican Airlines

Deal found 9/13

$918

Fri 3/61:00 pmMSP - SCL

1 stop14h 55mLATAM Airlines

Sun 3/1510:40 pmSCL - MSP

1 stop17h 02mLATAM Airlines

Deal found 9/14

$922

Tue 11/1112:00 pmMSP - SCL

1 stop21h 15mAir Canada

Wed 11/198:55 pmSCL - MSP

1 stop27h 24mAir Canada

Deal found 9/15

$890

Tue 11/46:00 amMSP - SCL

2 stops23h 50mUnited Airlines

Tue 11/1810:45 pmSCL - MSP

1 stop14h 24mUnited Airlines

Deal found 9/14

$914

Wed 3/47:15 amMSP - SCL

2 stops22h 50mAmerican Airlines

Thu 3/129:15 pmSCL - MSP

2 stops17h 12mAmerican Airlines

Deal found 9/14

$938

Thu 12/116:00 amMSP - SCL

2 stops23h 50mUnited Airlines

Tue 1/2010:45 pmSCL - MSP

2 stops19h 46mUnited Airlines

Deal found 9/14

$918

Mon 2/99:55 amMSP - SCL

2 stops19h 55mUnited Airlines

Thu 2/1910:45 pmSCL - MSP

2 stops19h 46mUnited Airlines

Deal found 9/13

$918

Mon 2/98:00 amMSP - SCL

2 stops21h 50mUnited Airlines

Tue 2/2410:45 pmSCL - MSP

2 stops19h 46mUnited Airlines

Deal found 9/13

$918

Mon 12/82:06 pmMSP - SCL

1 stop15h 44mUnited Airlines

Tue 1/2010:45 pmSCL - MSP

2 stops21h 36mUnited Airlines

Deal found 9/14

$918

Last-minute flights from Minneapolis to Santiago
Discover last-minute flight deals from Minneapolis to Santiago. Data last updated September 15, 2025 and is based on user searches.

Mon 10/206:12 amMSP - SCL

2 stops30h 33mMultiple Airlines

Fri 10/319:05 pmSCL - MSP

3 stops28h 22mMultiple Airlines

Deal found 9/14

$639

Tue 10/2812:00 pmMSP - SCL

1 stop21h 15mAir Canada

Tue 11/48:55 pmSCL - MSP

1 stop21h 54mAir Canada

Deal found 9/13

$846

Tue 10/287:00 amMSP - SCL

3 stops38h 35mMultiple Airlines

Tue 11/48:55 pmSCL - MSP

1 stop21h 54mMultiple Airlines

Deal found 9/13

$857

Thu 10/306:18 amMSP - SCL

2 stops19h 17mMultiple Airlines

Wed 11/51:35 amSCL - MSP

2 stops23h 14mMultiple Airlines

Deal found 9/15

$758

One-way flights from Minneapolis to Santiago
Search for one-way flight options from Minneapolis to Santiago. Find affordable one-way fares based on user searches. Data last updated September 15, 2025.

Mon 2/212:00 pmMSP - SCL

1 stop21h 15mAir Canada

Deal found 9/15

$395

Mon 2/26:45 amMSP - SCL

3 stops52h 55mMultiple Airlines

Deal found 9/15

$396

Wed 12/2412:00 pmMSP - SCL

1 stop21h 15mAir Canada

Deal found 9/15

$444

Wed 12/243:18 pmMSP - SCL

2 stops50h 03mMultiple Airlines

Deal found 9/15

$454

Tue 2/179:57 amMSP - SCL

2 stops19h 53mUnited Airlines

Deal found 9/15

$568

Wed 9/246:26 amMSP - SCL

1 stop23h 29mAmerican Airlines

Deal found 9/12

$658

Tue 2/178:50 amMSP - SCL

3 stops23h 15mLATAM Airlines

Deal found 9/14

$688

Sat 9/209:31 amMSP - SCL

3 stops42h 29mMultiple Airlines

Deal found 9/15

$689

Sat 9/209:59 amMSP - SCL

1 stop18h 01mDelta

Deal found 9/15

$1,138

Wed 9/246:55 amMSP - SCL

3 stops36h 35mLATAM Airlines

Deal found 9/12

$1,911

Cheapflights Fare Finder

Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/20

6:12 am-2:45 pm

2 stops30h 33m

Santiago Arturo Merino Benitez

Fri 10/31

12:30 pm-3:00 pm

2 stops28h 30m

$641

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 2/20

12:00 pm-7:00 am

2 stops40h 00m

Santiago Arturo Merino Benitez

Fri 2/27

8:35 am-9:19 pm

2 stops39h 44m

$777

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 11/11

12:00 pm-12:15 pm

1 stop21h 15m

Santiago Arturo Merino Benitez

Wed 11/19

8:55 pm-9:19 pm

1 stop27h 24m

$890

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 11/11

6:00 am-8:50 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Wed 11/19

10:45 pm-4:58 pm

1 stop21h 13m

$914

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 11/4

6:00 am-8:50 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Tue 11/18

10:45 pm-10:09 am

1 stop14h 24m

$914

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/13

6:30 am-8:00 am

1 stop23h 30m

Santiago Arturo Merino Benitez

Mon 10/20

9:55 pm-5:16 pm

2 stops21h 21m

$918

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Thu 12/11

6:00 am-8:50 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Tue 1/20

10:45 pm-3:31 pm

2 stops19h 46m

$918

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 2/9

9:55 am-8:50 am

2 stops19h 55m

Santiago Arturo Merino Benitez

Thu 2/19

10:45 pm-3:31 pm

2 stops19h 46m

$918

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 2/9

8:00 am-8:50 am

2 stops21h 50m

Santiago Arturo Merino Benitez

Tue 2/24

10:45 pm-3:31 pm

2 stops19h 46m

$918

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 12/8

2:06 pm-8:50 am

1 stop15h 44m

Santiago Arturo Merino Benitez

Tue 1/20

10:45 pm-5:21 pm

2 stops21h 36m

$918

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 19 results

Best time to book a flight from Minneapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Santiago

How far ahead should I book a flight from Minneapolis to Santiago?

The best time to book flights from Minneapolis to Santiago is 57 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Minneapolis to Santiago?

Currently, April is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $752). Flying from Minneapolis to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SCL?

When flying from Minneapolis to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 35% versus a flight in the morning.

Reviews of airlines servicing Santiago

Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,954 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

LATAM Airlines

7.5

Good

1,847 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,929 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,954 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

How long is the flight from Minneapolis to Santiago?
Departing from Minneapolis to Santiago will take you 23h 50m. The distance between Minneapolis and Santiago is about 5584 mi. Both multi-stop and nonstop flights can be found to your destination and back.
What are the cheapest airlines flying from Minneapolis to Santiago round-trip?
Flying on American Airlines is currently your cheapest option to Santiago, with prices starting at $745. Additional round-trip tickets that might be worth considering are offered by LATAM Airlines and Delta, with the lowest prices starting at $815 and $853, respectively. These flights start at 30% lower than the current average price 3 months from now.
Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?
Yes. In addition to deals on Minneapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Minneapolis to Santiago?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Santiago.
Can I find deals for business class flights from Minneapolis to Santiago?
Yes. Cheapflights offers flight deals from Minneapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Minneapolis to Santiago?
Currently, April is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $752). Flying from Minneapolis to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Minneapolis to Santiago

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Other flights to Santiago

Top 4 airlines flying from Minneapolis to Santiago

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$745	Average$952	FlexibilityNo cancel fee	On-time71%
LATAM Airlines	Cheapest$815	Average$1,138	FlexibilityNo cancel fee	On-time81%
United Airlines	Cheapest$853	Average$1,125	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$853	Average$1,169	FlexibilityNo cancel fee	On-timeN/A

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$395+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/2. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Minneapolis to Santiago with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Minneapolis St Paul to Santiago Arturo Merino Benitez are usually found in October or January, booked 57 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from Minneapolis to Santiago

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Minneapolis to Santiago

Cheapest flights from Minneapolis to SantiagoExplore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Best time to book a flight from Minneapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Santiago

How far ahead should I book a flight from Minneapolis to Santiago?

What is the cheapest month to book a flight from Minneapolis to Santiago?

What is the cheapest time of day to fly from MSP to SCL?

Reviews of airlines servicing Santiago

Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Minneapolis to Santiago?

What are the cheapest airlines flying from Minneapolis to Santiago round-trip?

Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?

How can I find direct flights from Minneapolis to Santiago?

Can I find deals for business class flights from Minneapolis to Santiago?

What is the cheapest month to book a flight from Minneapolis to Santiago?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Minneapolis to Santiago

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Minneapolis to Santiago

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Book with Flexibility

Travel Smart

Cheapest flights from Minneapolis to Santiago
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.