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$357+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/23. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Minneapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$887
(Mytrip)

One-way from

$357
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$953
Provider with most accurate pricing for Minneapolis St Paul-Santiago Arturo Merino Benitez flight deals.
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Provider most trusted by Cheapflights users for Minneapolis St Paul-Santiago Arturo Merino Benitez flights.
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From Minneapolis St Paul to Santiago Arturo Merino Benitez
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One-way flight from Minneapolis St Paul to Santiago Arturo Merino Benitez
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High demand for flights, 5% potential price rise
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Cheapest flight prices on average. 1% potential price decrease ($13 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Minneapolis to Santiago

Cheapest flights from Minneapolis to Santiago
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This Mytrip deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/96:36 am
MSP
-
SCL
2 stops24h 58m
Multiple Airlines
Wed 2/189:05 pm
SCL
-
MSP
2 stops20h 55m
Multiple Airlines
Deal found 1/13$887
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/232:01 pm
MSP
-
SCL
1 stop15h 49m
United Airlines
Thu 3/510:45 pm
SCL
-
MSP
1 stop21h 30m
United Airlines
Deal found 1/15$895
This Expedia deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:00 pm
MSP
-
SCL
1 stop21h 15m
Multiple Airlines
Tue 5/198:40 pm
SCL
-
MSP
1 stop14h 50m
Multiple Airlines
Deal found 1/13$902
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2410:47 am
MSP
-
SCL
1 stop18h 13m
American Airlines
Tue 5/198:30 pm
SCL
-
MSP
1 stop27h 22m
American Airlines
Deal found 1/14$908
This American Airlines deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:00 am
MSP
-
SCL
1 stop24h 50m
American Airlines
Mon 4/138:30 pm
SCL
-
MSP
2 stops22h 08m
American Airlines
Deal found 1/13$913
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/97:35 am
MSP
-
SCL
1 stop22h 15m
United Airlines
Wed 2/1810:45 pm
SCL
-
MSP
1 stop17h 14m
United Airlines
Deal found 1/12$915
This United Airlines deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/117:35 am
MSP
-
SCL
1 stop22h 15m
United Airlines
Tue 2/1710:45 pm
SCL
-
MSP
1 stop17h 14m
United Airlines
Deal found 1/12$931
This Mytrip deal was found by Cheapflights users on 1/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/118:00 am
MSP
-
SCL
3 stops34h 55m
Multiple Airlines
Wed 2/189:05 pm
SCL
-
MSP
2 stops20h 55m
Multiple Airlines
Deal found 1/12$933

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Fly from

Minneapolis

Fly to

Santiago

Route

Depart

Return

Price

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 3/10

1:55 pm-7:50 am

1 stop15h 55m

Santiago Arturo Merino Benitez

Tue 3/24

9:45 pm-12:57 pm

1 stop17h 12m

$895

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 2/23

2:01 pm-8:50 am

1 stop15h 49m

Santiago Arturo Merino Benitez

Thu 3/5

10:45 pm-5:15 pm

1 stop21h 30m

$895

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 4/6

10:47 am-7:50 am

2 stops20h 03m

Santiago Arturo Merino Benitez

Mon 4/13

8:30 pm-3:50 pm

2 stops20h 20m

$900

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 2/23

3:07 pm-8:05 am

1 stop13h 58m

Santiago Arturo Merino Benitez

Thu 3/5

10:15 pm-5:21 pm

2 stops22h 06m

$900

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Wed 3/18

4:30 pm-11:15 am

1 stop16h 45m

Santiago Arturo Merino Benitez

Sun 3/22

12:35 pm-9:36 pm

3 stops35h 01m

$915

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 2/9

1:57 pm-8:50 am

1 stop15h 53m

Santiago Arturo Merino Benitez

Thu 2/19

10:45 pm-12:59 pm

1 stop17h 14m

$915

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 2/9

1:57 pm-8:50 am

1 stop15h 53m

Santiago Arturo Merino Benitez

Tue 2/17

10:45 pm-12:59 pm

1 stop17h 14m

$915

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 3/23

8:04 pm-4:00 am

2 stops29h 56m

$357

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Thu 3/26

9:42 am-10:15 pm

3 stops34h 33m

$360

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 3/27

6:50 pm-6:40 am

3 stops57h 50m

$360

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/12

Showing 1-10 of 13 results
1
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Compare providers for flights from Minneapolis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Santiago in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
AranGrantPrice Accuracy2 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
OvagoPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Minneapolis-Santiago flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Minneapolis-Santiago flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Minneapolis-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Minneapolis-Santiago flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Minneapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Santiago

What is the cheapest month to book a flight from Minneapolis to Santiago?

Currently, September is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $616). Flying from Minneapolis to Santiago in May is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated January 15, 2026.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta, LATAM Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,049 reviews

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,049 reviews
Delta
7.9
Good
8,049 reviews

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.5
Good
1,904 reviews
Delta
7.9
Good
8,049 reviews

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,164 reviews
Delta
7.9
Good
8,049 reviews

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,132 reviews
Delta
7.9
Good
8,049 reviews

Food

7.2

Entertainment

7.8

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Minneapolis to Santiago?

    Departing from Minneapolis to Santiago will take you 15h 55m. The distance between Minneapolis and Santiago is about 5584 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Minneapolis to Santiago round-trip?

    Flying on American Airlines is currently your cheapest option to Santiago, with prices starting at $718. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $853 and $853, respectively. These flights start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Santiago.

  • Can I find deals for business class flights from Minneapolis to Santiago?

    Yes. Cheapflights offers flight deals from Minneapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Santiago?

    Currently, September is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $616). Flying from Minneapolis to Santiago in May is currently the most expensive (average of $1,146). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Minneapolis to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Minneapolis to Santiago

Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$718Average$1,074FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$853Average$993FlexibilityNo cancel feeOn-time69%
DeltaCheapest$853Average$1,173FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$893Average$1,159FlexibilityNo cancel feeOn-time81%

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