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$335+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
Aug 12 — Aug 191
Tue 8/12
Tue 8/19
1 adult, Economy
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Cheapflights Tip: The best prices from Minneapolis St Paul to Santiago Arturo Merino Benitez are usually found in August or October, booked 57 days in advance, depart on a Monday or Saturday and return on a Wednesday

Cheap flight deals from Minneapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 7, 2025.

Round-trip from

$859
(Mytrip)

One-way from

$335
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$933
From Minneapolis St Paul to Santiago Arturo Merino Benitez
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One-way flight from Minneapolis St Paul to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 1% potential increase in price ($21 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Minneapolis to Santiago

Cheapest flights from Minneapolis to Santiago
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2025.

This Mytrip deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/316:00 amMSP - SCL
3 stops19h 35mMultiple Airlines
Thu 9/43:35 amSCL - MSP
3 stops29h 51mMultiple Airlines
Deal found 8/6$859
This Mytrip deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:54 pmMSP - SCL
3 stops35h 06mMultiple Airlines
Fri 10/103:30 pmSCL - MSP
2 stops25h 33mMultiple Airlines
Deal found 8/6$862
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/66:30 amMSP - SCL
3 stops37h 25mMultiple Airlines
Mon 11/104:25 pmSCL - MSP
3 stops27h 29mMultiple Airlines
Deal found 8/7$880
This Mytrip deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/16:36 amMSP - SCL
3 stops19h 54mMultiple Airlines
Thu 9/43:35 amSCL - MSP
3 stops29h 51mMultiple Airlines
Deal found 8/6$884
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/311:05 amMSP - SCL
1 stop18h 45mUnited Airlines
Mon 11/1010:45 pmSCL - MSP
2 stops19h 55mUnited Airlines
Deal found 8/7$930
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/163:00 pmMSP - SCL
3 stops30h 30mMultiple Airlines
Tue 9/233:30 pmSCL - MSP
3 stops31h 13mMultiple Airlines
Deal found 8/7$933
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:00 amMSP - SCL
2 stops23h 50mUnited Airlines
Tue 11/410:45 pmSCL - MSP
1 stop21h 13mUnited Airlines
Deal found 8/7$934

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Fly from

Minneapolis

Fly to

Santiago

Route

Depart

Return

Price

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Sun 8/31

6:00 am-2:35 am

3 stops19h 35m

Santiago Arturo Merino Benitez

Thu 9/4

3:35 am-8:26 am

3 stops29h 51m

$859

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 9/26

4:54 pm-6:00 am

3 stops35h 06m

Santiago Arturo Merino Benitez

Fri 10/10

3:30 pm-3:03 pm

2 stops25h 33m

$862

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/6

6:30 am-9:55 pm

3 stops37h 25m

Santiago Arturo Merino Benitez

Mon 11/10

4:25 pm-4:54 pm

3 stops27h 29m

$880

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 9/1

6:36 am-3:30 am

3 stops19h 54m

Santiago Arturo Merino Benitez

Thu 9/4

3:35 am-8:26 am

3 stops29h 51m

$884

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 11/3

11:05 am-8:50 am

1 stop18h 45m

Santiago Arturo Merino Benitez

Thu 11/6

10:45 pm-10:09 am

1 stop14h 24m

$930

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 9/16

3:00 pm-11:30 pm

3 stops30h 30m

Santiago Arturo Merino Benitez

Tue 9/23

3:30 pm-8:43 pm

3 stops31h 13m

$933

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 10/27

6:00 am-7:50 am

2 stops23h 50m

Santiago Arturo Merino Benitez

Tue 11/4

10:45 pm-4:58 pm

1 stop21h 13m

$934

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Thu 10/23

9:31 am-10:10 pm

3 stops34h 39m

$335

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Sat 9/13

8:05 pm-11:30 pm

3 stops49h 25m

$381

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Wed 11/12

3:45 pm-3:20 pm

3 stops44h 35m

$398

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/7

Showing 1-10 of 12 results
1
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Best time to book a flight from Minneapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Santiago

How far ahead should I book a flight from Minneapolis to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Minneapolis to Santiago. Price data was last updated on August 1, 2025.

The best time to book flights from Minneapolis to Santiago is 57 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Minneapolis to Santiago?

Currently, April is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $752). Flying from Minneapolis to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to SCL?

Find hourly flight availability from Minneapolis to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 7, 2025.

When flying from Minneapolis to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 35% versus a flight in the morning.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated August 7, 2025.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as LATAM Airlines, Copa Airlines, and United Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,834 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Overall

7.5

Comfort

7.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
LATAM Airlines
7.5
Good
1,834 reviews
LATAM Airlines
7.5
Good
1,834 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Overall

7.5

Comfort

7.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Copa Airlines
7.5
Good
1,500 reviews
LATAM Airlines
7.5
Good
1,834 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Overall

7.5

Comfort

7.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
United Airlines
7.4
Good
8,916 reviews
LATAM Airlines
7.5
Good
1,834 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Overall

7.5

Comfort

7.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
Turkish Airlines
7.3
Good
3,934 reviews
LATAM Airlines
7.5
Good
1,834 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Overall

7.5

Comfort

7.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing
American Airlines
7.2
Good
10,000 reviews
LATAM Airlines
7.5
Good
1,834 reviews

Boarding

7.6

Entertainment

7.0

Food

6.7

Overall

7.5

Comfort

7.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Murilo,Jun 2025

SFO - LAX

I had mixed feelings regarding this flight. Called several times Latam and Delta regarding the purchase of checked baggage and price. I was told 80 dollars, could not buy it ahead of time,, they told me it was not Possible, that I had to buy at the airport. Check in my luggage the attendant says 80 dollars but I was charged 200 . No one could get me a solid answer why. Very disappointing

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Santiago.

  • Can I find deals for business class flights from Minneapolis to Santiago?

    Yes. Cheapflights offers flight deals from Minneapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $752). Flying from Minneapolis to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Minneapolis to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Minneapolis to Santiago

Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$737Average$952FlexibilityNo cancel feeOn-time71%
LATAM AirlinesCheapest$815Average$1,110FlexibilityNo cancel feeOn-time81%
United AirlinesCheapest$853Average$1,122FlexibilityNo cancel feeOn-time69%
DeltaCheapest$853Average$1,155FlexibilityNo cancel feeOn-timeN/A

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