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$349+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
Apr 29 — May 61
Wed 4/29
Wed 5/6
1 adult, Economy
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Cheap flight deals from Minneapolis to Santiago

Cheapest flights from Minneapolis to Santiago
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 30, 2026.

This Trip.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2510:45 am
MSP
-
SCL
2 stops34h 58m
Multiple Airlines
Fri 5/12:22 am
SCL
-
MSP
2 stops32h 17m
Multiple Airlines
Deal found 3/26$750
This Air Canada deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/31:10 pm
MSP
-
SCL
2 stops43h 05m
Air Canada
Thu 12/37:55 pm
SCL
-
MSP
1 stop22h 54m
Air Canada
Deal found 3/29$884
This Air Canada deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/64:30 pm
MSP
-
SCL
1 stop15h 45m
Air Canada
Sat 11/147:55 pm
SCL
-
MSP
1 stop28h 24m
Air Canada
Deal found 3/27$922
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/810:14 am
MSP
-
SCL
2 stops17h 49m
United Airlines
Mon 7/2712:06 am
SCL
-
MSP
2 stops35h 47m
United Airlines
Deal found 3/26$968
This American Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:24 am
MSP
-
SCL
1 stop23h 41m
American Airlines
Wed 7/228:30 pm
SCL
-
MSP
2 stops21h 45m
American Airlines
Deal found 3/27$970
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/216:24 am
MSP
-
SCL
1 stop23h 41m
American Airlines
Mon 6/229:00 pm
SCL
-
MSP
1 stop28h 22m
American Airlines
Deal found 3/25$979
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:03 am
MSP
-
SCL
1 stop24h 02m
American Airlines
Tue 4/288:35 pm
SCL
-
MSP
2 stops19h 31m
American Airlines
Deal found 3/25$984
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:10 am
MSP
-
SCL
1 stop23h 40m
American Airlines
Thu 8/138:30 pm
SCL
-
MSP
1 stop27h 25m
American Airlines
Deal found 3/28$1,004
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:14 am
MSP
-
SCL
2 stops32h 09m
United Airlines
Wed 7/2912:06 am
SCL
-
MSP
2 stops24h 23m
United Airlines
Deal found 3/26$1,018
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/86:10 am
MSP
-
SCL
1 stop23h 40m
American Airlines
Wed 7/298:30 pm
SCL
-
MSP
2 stops19h 48m
American Airlines
Deal found 3/26$1,020

Find flight deals from Minneapolis to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 30, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$750
(Trip.com)

One-way from

$349
(Trip.com)

Popular in

October

Cheapest in

April

Average price

$1,105
Provider with most accurate pricing for Minneapolis St Paul-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Minneapolis St Paul-Santiago Arturo Merino Benitez flights.
Search Deals
From Minneapolis St Paul to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Minneapolis St Paul to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($16 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 5/11

7:30 am-5:10 am

2 stops20h 40m

Santiago Arturo Merino Benitez

Mon 5/18

11:17 am-10:43 pm

2 stops36h 26m

$968

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Wed 7/8

10:14 am-10:43 pm

2 stops35h 29m

Santiago Arturo Merino Benitez

Wed 7/29

12:06 am-5:12 pm

2 stops18h 06m

$968

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 6/15

6:24 am-7:05 am

1 stop23h 41m

Santiago Arturo Merino Benitez

Wed 7/22

8:30 pm-5:34 pm

2 stops22h 04m

$970

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Thu 5/21

6:24 am-7:05 am

1 stop23h 41m

Santiago Arturo Merino Benitez

Mon 6/22

9:00 pm-5:03 pm

2 stops21h 03m

$970

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Tue 4/21

6:03 am-7:05 am

1 stop24h 02m

Santiago Arturo Merino Benitez

Tue 4/28

8:35 pm-3:06 pm

2 stops19h 31m

$984

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Mon 5/11

2:36 pm-7:05 am

2 stops15h 29m

Santiago Arturo Merino Benitez

Mon 5/18

8:35 pm-10:52 pm

1 stop27h 17m

$984
Quickest round-trip

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Thu 7/9

7:35 am-3:00 am

2 stops18h 25m

Santiago Arturo Merino Benitez

Sat 7/25

12:43 am-5:12 pm

2 stops17h 29m

$1,018

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Fri 7/10

10:14 am-7:23 pm

2 stops32h 09m

Santiago Arturo Merino Benitez

Wed 7/29

12:06 am-11:29 pm

2 stops24h 23m

$1,018

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Sat 7/11

7:35 am-5:03 am

2 stops20h 28m

Santiago Arturo Merino Benitez

Wed 7/29

12:06 am-11:29 pm

2 stops24h 23m

$1,018

MinneapolisSantiago

MSP - SCL

MSPSCL

Minneapolis St Paul

Thu 8/13

10:22 am-10:43 pm

2 stops35h 21m

Santiago Arturo Merino Benitez

Fri 8/21

4:14 am-11:19 pm

2 stops44h 05m

$1,018

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Minneapolis to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Santiago in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars
OvagoPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Minneapolis-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Minneapolis-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Minneapolis-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Minneapolis-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Minneapolis to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Santiago

What is the cheapest month to book a flight from Minneapolis to Santiago?

Currently, September is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $620). Flying from Minneapolis to Santiago in May is currently the most expensive (average of $1,145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 30, 2026.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,357 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,357 reviews
Delta
7.9
Good
8,357 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
LATAM Airlines
7.4
Good
1,901 reviews
Delta
7.9
Good
8,357 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,509 reviews
Delta
7.9
Good
8,357 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.1
Good
11,522 reviews
Delta
7.9
Good
8,357 reviews

Boarding

8.1

Entertainment

7.8

Comfort

7.9

Food

7.2

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Minneapolis to Santiago?

    Departing from Minneapolis to Santiago will take you 20h 40m. The distance between Minneapolis and Santiago is about 5584 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines flying from Minneapolis to Santiago round-trip?

    Flying on American Airlines is currently your cheapest option to Santiago, with prices starting at $518. Additional round-trip tickets that might be worth considering are offered by Delta and United Airlines, with the lowest prices starting at $853 and $853, respectively. These flights start at 52% lower than the current average price 3 months from now.

  • Can I find deals for flights from Minneapolis to Santiago that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Santiago.

  • Can I find deals for business class flights from Minneapolis to Santiago?

    Yes. Cheapflights offers flight deals from Minneapolis to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Santiago?

    Currently, September is the cheapest month in which you can book a flight from Minneapolis to Santiago (average of $620). Flying from Minneapolis to Santiago in May is currently the most expensive (average of $1,145). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Minneapolis to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
Sioux Falls to Santiago flights

Top 4 airlines flying from Minneapolis to Santiago

Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$518Average$1,074FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$853Average$973FlexibilityNo cancel feeOn-time69%
DeltaCheapest$853Average$1,223FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$916Average$1,173FlexibilityNo cancel feeOn-time81%

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