$309+ Cheap flights from Minneapolis (MSP) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — SCL
Jun 26 — Jul 31
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to Santiago with Cheapflights
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Best
Last-minute
One-way
Cheapest flights from Minneapolis to SantiagoExplore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 27, 2026.
Explore the most affordable flight options available from Minneapolis to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 27, 2026.
This Mytrip deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am
MSP
- SCL
2 stops18h 25m
Multiple Airlines
Sat 11/148:55 pm
SCL
- MSP
1 stop27h 25m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$866
This Air Canada deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:10 pm
MSP
- SCL
2 stops43h 05m
Air Canada
Sat 11/148:55 pm
SCL
- MSP
1 stop27h 25m
Air Canada
Deal found 5/24![Air Canada logo]()
$883
This KAYAK deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:30 pm
MSP
- SCL
1 stop15h 45m
Avianca
Mon 11/98:55 pm
SCL
- MSP
1 stop21h 55m
Avianca
Deal found 5/24![Avianca logo]()
$884
This Air Canada deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:10 pm
MSP
- SCL
2 stops44h 05m
Air Canada
Tue 11/108:55 pm
SCL
- MSP
1 stop21h 55m
Air Canada
Deal found 5/25![Air Canada logo]()
$885
This Air Canada deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/212:00 pm
MSP
- SCL
1 stop20h 15m
Air Canada
Mon 11/98:55 pm
SCL
- MSP
1 stop27h 25m
Air Canada
Deal found 5/24![Air Canada logo]()
$887
This Air Canada deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/24:30 pm
MSP
- SCL
1 stop15h 45m
Air Canada
Thu 11/128:55 pm
SCL
- MSP
2 stops26h 15m
Air Canada
Deal found 5/24![Air Canada logo]()
$890
This Air Canada deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:10 pm
MSP
- SCL
2 stops43h 05m
Air Canada
Wed 12/27:25 am
SCL
- MSP
2 stops35h 25m
Air Canada
Deal found 5/26![Air Canada logo]()
$893
This Trip.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:20 am
MSP
- SCL
1 stop23h 05m
Multiple Airlines
Thu 6/1111:05 pm
SCL
- MSP
1 stop15h 59m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$903
Best flights from Minneapolis to SantiagoDiscover carefully curated flight deals from Minneapolis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 27, 2026.
Discover carefully curated flight deals from Minneapolis to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 27, 2026.
This Air Canada deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:10 pm
MSP
- SCL
2 stops43h 05m
Air Canada
Sat 11/148:55 pm
SCL
- MSP
1 stop27h 25m
Air Canada
Deal found 5/24![Air Canada logo]()
$883
This Mytrip deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:25 am
MSP
- SCL
2 stops29h 50m
Multiple Airlines
Wed 6/1012:30 am
SCL
- MSP
2 stops22h 22m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$1,026
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:00 am
MSP
- SCL
2 stops22h 00m
American Airlines
Tue 9/18:30 pm
SCL
- MSP
2 stops18h 18m
American Airlines
Deal found 5/23![American Airlines logo]()
$1,165
This Delta deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/221:00 pm
MSP
- SCL
2 stops16h 55m
Delta
Mon 7/611:00 pm
SCL
- MSP
2 stops20h 18m
Delta
Deal found 5/25![Delta logo]()
$1,186
This United Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:35 am
MSP
- SCL
2 stops17h 15m
United Airlines
Sun 6/2812:01 am
SCL
- MSP
2 stops18h 11m
United Airlines
Deal found 5/25![United Airlines logo]()
$1,198
This LATAM Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/258:55 am
MSP
- SCL
2 stops27h 30m
LATAM Airlines
Sat 7/410:55 pm
SCL
- MSP
1 stop15h 55m
LATAM Airlines
Deal found 5/22![LATAM Airlines logo]()
$1,281
This Air Canada deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/84:30 pm
MSP
- SCL
1 stop15h 45m
Air Canada
Thu 11/128:55 pm
SCL
- MSP
1 stop27h 25m
Air Canada
Deal found 5/22![Air Canada logo]()
$937
Last-minute flights from Minneapolis to SantiagoDiscover last-minute flight deals from Minneapolis to Santiago. Data last updated May 27, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to Santiago. Data last updated May 27, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/76:20 am
MSP
- SCL
1 stop23h 05m
Multiple Airlines
Thu 6/1111:05 pm
SCL
- MSP
1 stop15h 59m
Multiple Airlines
Deal found 5/22![Multiple Airlines logo]()
$903
This Trip.com deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:05 am
MSP
- SCL
1 stop22h 20m
Multiple Airlines
Sun 6/1411:05 pm
SCL
- MSP
1 stop15h 59m
Multiple Airlines
Deal found 5/24![Multiple Airlines logo]()
$986
This Mytrip deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:55 am
MSP
- SCL
3 stops28h 35m
Multiple Airlines
Mon 6/296:40 am
SCL
- MSP
3 stops32h 25m
Multiple Airlines
Deal found 5/25![Multiple Airlines logo]()
$914
This LATAM Airlines deal was found by Cheapflights users on 5/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2212:53 pm
MSP
- SCL
1 stop16h 32m
LATAM Airlines
Mon 6/2911:05 pm
SCL
- MSP
1 stop15h 45m
LATAM Airlines
Deal found 5/25![LATAM Airlines logo]()
$1,087
This Mytrip deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:20 am
MSP
- SCL
3 stops29h 45m
Multiple Airlines
Tue 8/183:20 pm
SCL
- MSP
2 stops23h 21m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$1,082
One-way flights from Minneapolis to SantiagoSearch for one-way flight options from Minneapolis to Santiago. Find affordable one-way fares based on user searches. Data last updated May 27, 2026.
Search for one-way flight options from Minneapolis to Santiago. Find affordable one-way fares based on user searches. Data last updated May 27, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/188:35 am
MSP
- SCL
2 stops17h 25m
Multiple Airlines
Deal found 5/26![Multiple Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:04 am
MSP
- SCL
1 stop23h 21m
American Airlines
Deal found 5/26![American Airlines logo]()
$653
Find flight deals from Minneapolis to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $866 (Mytrip) |
One-way from | $309 (Kiwi.com) |
Popular in | May |
Cheapest in | January |
Average price | $1,497 |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 27, 2026.
Use the filters below to find and compare flights from Minneapolis to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Sat 11/7
1:10 pm-11:15 am
2 stops43h 05m
Santiago Arturo Merino Benitez
Sat 11/14
8:55 pm-9:20 pm
1 stop27h 25m
$883
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Sun 11/8
4:30 pm-11:15 am
1 stop15h 45m
Santiago Arturo Merino Benitez
Thu 11/12
8:55 pm-9:20 pm
1 stop27h 25m
$937
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Sun 6/7
7:25 am-2:15 pm
2 stops29h 50m
Santiago Arturo Merino Benitez
Wed 6/10
12:30 am-9:52 pm
2 stops22h 22m
$1,026
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Tue 7/21
8:00 am-7:00 am
2 stops22h 00m
Santiago Arturo Merino Benitez
Tue 9/1
8:30 pm-1:48 pm
2 stops18h 18m
$1,165
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Mon 6/22
1:00 pm-6:55 am
2 stops16h 55m
Santiago Arturo Merino Benitez
Mon 7/6
11:00 pm-6:18 pm
2 stops20h 18m
$1,186
Quickest round-trip
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Mon 6/22
7:35 am-1:50 am
2 stops17h 15m
Santiago Arturo Merino Benitez
Sun 6/28
12:01 am-5:12 pm
2 stops18h 11m
$1,198
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Thu 6/25
8:55 am-1:25 pm
2 stops27h 30m
Santiago Arturo Merino Benitez
Sat 7/4
10:55 pm-1:50 pm
1 stop15h 55m
$1,281
Cheapest one-way
Quickest one-way
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Tue 8/18
8:35 am-3:00 am
2 stops17h 25m
$309
MinneapolisSantiago
MSP - SCL
MSPSCL
Minneapolis St Paul
Tue 8/18
6:04 am-6:25 am
1 stop23h 21m
$653
Sorted by cheapest first
Compare providers for flights from Minneapolis to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Minneapolis to Santiago in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Minneapolis-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Minneapolis-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Minneapolis-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Minneapolis-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Minneapolis-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Minneapolis to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Minneapolis with our price prediction graph.
MSP-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to Santiago
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated May 27, 2026.
Read through reviews of airlines operating flights from Minneapolis to Santiago, such as Delta,LATAM Airlines, andUnited Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Overall
7.9
Crew
8.5
Food
7.2
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Santiago by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minneapolis to Santiago by cabin class
Find flights from Minneapolis to Santiago, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and Santiago flights
Browse other Minneapolis and Santiago flight options. Last updated on May 27, 2026.
Other flights from Minneapolis
Browse through other flights departing from Minneapolis. Flights are based on user searches made on Cheapflights and were last updated on May 27, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to Santiago
Explore flights to Santiago departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 27, 2026.
Top 4 airlines flying from Minneapolis to Santiago
Discover the top 4 airlines that operate flights from Minneapolis to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$718 | Average$1,225 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$853 | Average$993 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$893 | Average$1,320 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$933 | Average$1,226 | FlexibilityNo cancel fee | On-time81% |