$254+ Cheap flights from Denver (DEN) to Santiago (SCL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Denver to Santiago
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Cheapest flights from Denver to SantiagoExplore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:00 pm
DEN
- SCL
2 stops16h 55m
LATAM Airlines
Tue 8/2511:00 pm
SCL
- DEN
2 stops20h 58m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$614
This FlightHub deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/912:00 pm
DEN
- SCL
1 stop17h 15m
LATAM Airlines
Thu 8/2011:25 pm
SCL
- DEN
1 stop20h 45m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$622
This Copa Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:43 pm
DEN
- SCL
1 stop22h 00m
Copa Airlines
Wed 9/93:56 am
SCL
- DEN
1 stop17h 15m
Copa Airlines
Deal found 3/9![Copa Airlines logo]()
$623
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:00 pm
DEN
- SCL
2 stops16h 55m
LATAM Airlines
Mon 9/288:40 pm
SCL
- DEN
1 stop18h 01m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$627
This KAYAK deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/23:10 pm
DEN
- SCL
1 stop14h 05m
LATAM Airlines
Fri 9/1811:25 pm
SCL
- DEN
1 stop21h 45m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$635
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:45 pm
DEN
- SCL
1 stop15h 05m
American Airlines
Wed 8/128:30 pm
SCL
- DEN
1 stop17h 42m
American Airlines
Deal found 3/9![American Airlines logo]()
$638
This LATAM Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/59:35 am
DEN
- SCL
1 stop19h 40m
LATAM Airlines
Wed 8/128:40 pm
SCL
- DEN
1 stop16h 14m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$639
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:10 pm
DEN
- SCL
1 stop14h 05m
Delta
Sun 8/2311:25 pm
SCL
- DEN
2 stops21h 45m
Delta
Deal found 3/8![Delta logo]()
$640
This BusinessClass deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:25 am
DEN
- SCL
2 stops32h 00m
LATAM Airlines
Fri 7/3111:00 pm
SCL
- DEN
2 stops20h 58m
LATAM Airlines
Deal found 3/8![LATAM Airlines logo]()
$642
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 am
DEN
- SCL
1 stop23h 10m
Delta
Mon 9/148:40 pm
SCL
- DEN
1 stop30h 05m
Delta
Deal found 3/9![Delta logo]()
$644
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/111:45 pm
DEN
- SCL
1 stop29h 05m
American Airlines
Sat 8/158:30 pm
SCL
- DEN
1 stop17h 42m
American Airlines
Deal found 3/8![American Airlines logo]()
$646
Best flights from Denver to SantiagoDiscover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from Denver to Santiago that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/44:40 pm
DEN
- SCL
2 stops26h 15m
Delta
Thu 9/1711:05 pm
SCL
- DEN
2 stops21h 53m
Delta
Deal found 3/9![Delta logo]()
$635
This Copa Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2410:43 pm
DEN
- SCL
1 stop22h 00m
Copa Airlines
Wed 9/93:56 am
SCL
- DEN
1 stop17h 15m
Copa Airlines
Deal found 3/10![Copa Airlines logo]()
$673
This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/287:20 am
DEN
- SCL
2 stops21h 30m
American Airlines
Sun 8/308:30 pm
SCL
- DEN
1 stop17h 42m
American Airlines
Deal found 3/11![American Airlines logo]()
$690
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/289:35 am
DEN
- SCL
2 stops18h 25m
Delta
Mon 9/711:25 pm
SCL
- DEN
2 stops18h 46m
Delta
Deal found 3/9![Delta logo]()
$640
This Copa Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/210:43 pm
DEN
- SCL
1 stop22h 00m
Copa Airlines
Fri 8/214:46 am
SCL
- DEN
1 stop15h 34m
Copa Airlines
Deal found 3/8![Copa Airlines logo]()
$693
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/43:10 pm
DEN
- SCL
1 stop14h 05m
Delta
Sun 8/2311:25 pm
SCL
- DEN
2 stops21h 45m
Delta
Deal found 3/8![Delta logo]()
$640
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:05 am
DEN
- SCL
1 stop23h 10m
Delta
Mon 9/148:40 pm
SCL
- DEN
1 stop30h 05m
Delta
Deal found 3/9![Delta logo]()
$644
This Delta deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/710:45 am
DEN
- SCL
1 stop18h 30m
Delta
Sun 8/1611:25 pm
SCL
- DEN
1 stop25h 33m
Delta
Deal found 3/10![Delta logo]()
$685
This Delta deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/610:45 am
DEN
- SCL
1 stop18h 30m
Delta
Sun 8/168:40 pm
SCL
- DEN
1 stop16h 14m
Delta
Deal found 3/11![Delta logo]()
$685
This Delta deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:05 am
DEN
- SCL
2 stops20h 30m
Delta
Tue 7/1411:00 pm
SCL
- DEN
2 stops23h 19m
Delta
Deal found 3/12![Delta logo]()
$690
Last-minute flights from Denver to SantiagoDiscover last-minute flight deals from Denver to Santiago. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from Denver to Santiago. Data last updated March 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:33 pm
DEN
- SCL
1 stop16h 17m
American Airlines
Tue 4/288:35 pm
SCL
- DEN
1 stop29h 04m
American Airlines
Deal found 3/9![American Airlines logo]()
$834
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:17 pm
DEN
- SCL
2 stops18h 48m
LATAM Airlines
Wed 4/157:50 am
SCL
- DEN
2 stops18h 46m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$840
This eDestinos deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1211:49 pm
DEN
- SCL
2 stops33h 16m
Multiple Airlines
Thu 4/3011:25 am
SCL
- DEN
2 stops48h 15m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$656
This FlightHub deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/151:25 pm
DEN
- SCL
2 stops15h 30m
LATAM Airlines
Wed 4/2211:25 pm
SCL
- DEN
1 stop20h 30m
LATAM Airlines
Deal found 3/9![LATAM Airlines logo]()
$809
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/189:30 pm
DEN
- SCL
1 stop30h 05m
Multiple Airlines
Tue 4/285:00 am
SCL
- DEN
2 stops30h 40m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$841
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2111:05 pm
DEN
- SCL
1 stop28h 30m
Multiple Airlines
Tue 4/285:00 am
SCL
- DEN
2 stops30h 40m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$800
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:25 pm
DEN
- SCL
1 stop16h 40m
American Airlines
Tue 4/288:35 pm
SCL
- DEN
1 stop29h 04m
American Airlines
Deal found 3/9![American Airlines logo]()
$812
One-way flights from Denver to SantiagoSearch for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from Denver to Santiago. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This eDestinos deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:05 pm
DEN
- SCL
2 stops34h 00m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/317:15 am
DEN
- SCL
3 stops44h 15m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$311
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:17 am
DEN
- SCL
3 stops43h 18m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:17 am
DEN
- SCL
3 stops43h 18m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$315
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:53 pm
DEN
- SCL
2 stops30h 42m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:00 am
DEN
- SCL
3 stops40h 35m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$339
This Kiwi.com deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1111:00 am
DEN
- SCL
3 stops40h 35m
Multiple Airlines
Deal found 3/12![Multiple Airlines logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/17:43 pm
DEN
- SCL
3 stops47h 22m
Multiple Airlines
Deal found 3/11![Multiple Airlines logo]()
$343
Find flight deals from Denver to Santiago
Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $614 (FlightHub) |
One-way from | $254 (eDestinos) |
Popular in | December |
Cheapest in | September |
Average price | $881 |
Cheapflights Fare Finder
Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Fri 9/4
4:40 pm-8:55 pm
2 stops26h 15m
Santiago Arturo Merino Benitez
Thu 9/17
11:05 pm-5:58 pm
2 stops21h 53m
$635
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Fri 8/28
9:35 am-6:00 am
2 stops18h 25m
Santiago Arturo Merino Benitez
Mon 9/7
11:25 pm-3:11 pm
2 stops18h 46m
$640
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Tue 8/4
3:10 pm-7:15 am
1 stop14h 05m
Santiago Arturo Merino Benitez
Sun 8/23
11:25 pm-7:10 pm
2 stops21h 45m
$640
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sat 9/5
6:05 am-7:15 am
1 stop23h 10m
Santiago Arturo Merino Benitez
Mon 9/14
8:40 pm-11:45 pm
1 stop30h 05m
$644
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Mon 8/24
10:43 pm-10:43 pm
1 stop22h 00m
Santiago Arturo Merino Benitez
Wed 9/9
3:56 am-6:11 pm
1 stop17h 15m
$673
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Fri 8/7
10:45 am-7:15 am
1 stop18h 30m
Santiago Arturo Merino Benitez
Sun 8/16
11:25 pm-10:58 pm
1 stop25h 33m
$685
Quickest round-trip
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Thu 8/6
10:45 am-7:15 am
1 stop18h 30m
Santiago Arturo Merino Benitez
Sun 8/16
8:40 pm-10:54 am
1 stop16h 14m
$685
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Fri 8/28
7:20 am-6:50 am
2 stops21h 30m
Santiago Arturo Merino Benitez
Sun 8/30
8:30 pm-12:12 pm
1 stop17h 42m
$690
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Mon 6/22
7:05 am-5:35 am
2 stops20h 30m
Santiago Arturo Merino Benitez
Tue 7/14
11:00 pm-8:19 pm
2 stops23h 19m
$690
DenverSantiago
DEN - SCL
DENSCL
Denver Intl
Sun 8/2
10:43 pm-10:43 pm
1 stop22h 00m
Santiago Arturo Merino Benitez
Fri 8/21
4:46 am-6:20 pm
1 stop15h 34m
$693
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Denver to Santiago
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Denver to Santiago in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*2 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Denver-Santiago flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Denver-Santiago flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Denver-Santiago flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Denver-Santiago flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Denver-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Denver to Santiago
Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
DEN-SCL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Denver to Santiago
How far ahead should I book a flight from Denver to Santiago?
Use this chart to determine the optimal time to book a round-trip flight from Denver to Santiago. Price data was last updated on March 6, 2026.
The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 63 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Denver to Santiago?
Currently, July is the cheapest month in which you can book a flight from Denver to Santiago (average of $384). Flying from Denver to Santiago in December is currently the most expensive (average of $662). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Santiago
Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated March 12, 2026.
Read reviews from past customers who have flown Delta,Copa Airlines, andLATAM Airlines from Denver to Santiago. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Food
7.2
Crew
8.5
Overall
7.9
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
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Denver and Santiago flights
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Top 6 airlines flying from Denver to Santiago
Discover the top 6 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$369 | Average$655 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$537 | Average$751 | FlexibilityNo cancel fee | On-time81% | |
| Cheapest$544 | Average$781 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$551 | Average$827 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$608 | Average$854 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$823 | Average$1,310 | FlexibilityNo cancel fee | On-timeN/A |