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$403+ Cheap flights from Denver (DEN) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/6. Fares are subject to change and may not be available on all flights or dates of travel.
DEN — SCL
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Denver Intl to Santiago Arturo Merino Benitez are usually found in April or May, booked 63 days in advance, depart on a Tuesday or Monday and return on a Tuesday

Cheap flight deals from Denver to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Denver (DEN) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$615
(Copa Airlines)

One-way from

$403
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$863
From Denver Intl to Santiago Arturo Merino Benitez
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One-way flight from Denver Intl to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 10% potential increase in price ($104 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Denver to Santiago

Cheapest flights from Denver to Santiago
Explore the most affordable flight options available from Denver to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Copa Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/110:42 pmDEN - SCL
1 stop22h 22mCopa Airlines
Mon 9/85:10 amSCL - DEN
1 stop15h 57mCopa Airlines
Deal found 6/10$615
This Justfly.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/112:32 pmDEN - SCL
1 stop15h 28mLATAM Airlines
Mon 9/811:30 pmSCL - DEN
2 stops21h 32mLATAM Airlines
Deal found 6/10$626
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/219:40 amDEN - SCL
2 stops18h 10mDelta
Wed 11/511:55 pmSCL - DEN
1 stop15h 35mDelta
Deal found 6/10$646
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/27:25 pmDEN - SCL
1 stop33h 25mUnited Airlines
Mon 11/1710:45 pmSCL - DEN
1 stop14h 14mUnited Airlines
Deal found 6/9$662
This Kiwi.com deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1212:34 amDEN - SCL
2 stops18h 41mMultiple Airlines
Sat 8/2311:00 amSCL - DEN
1 stop23h 21mMultiple Airlines
Deal found 6/12$730
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/78:34 amDEN - SCL
2 stops20h 21mAmerican Airlines
Mon 8/189:55 pmSCL - DEN
2 stops22h 09mAmerican Airlines
Deal found 6/11$758
This Aeromexico deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/141:22 pmDEN - SCL
1 stop27h 53mAeromexico
Tue 1/2011:25 pmSCL - DEN
1 stop16h 25mAeromexico
Deal found 6/10$954

Cheapflights Fare Finder

Customize your flight search to find flights from Denver to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Denver to Santiago that are best for you.

Fly from

Denver

Fly to

Santiago

Route

Depart

Return

Price

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 9/1

10:42 pm-11:04 pm

1 stop22h 22m

Santiago Arturo Merino Benitez

Mon 9/8

5:10 am-6:07 pm

1 stop15h 57m

$615

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Mon 9/1

12:32 pm-6:00 am

1 stop15h 28m

Santiago Arturo Merino Benitez

Mon 9/8

11:30 pm-6:02 pm

2 stops21h 32m

$626

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 10/21

4:40 pm-2:25 pm

2 stops18h 45m

Santiago Arturo Merino Benitez

Thu 11/6

11:15 pm-11:06 am

1 stop15h 51m

$646

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sun 11/2

7:25 pm-8:50 am

1 stop33h 25m

Santiago Arturo Merino Benitez

Thu 11/20

10:45 pm-12:37 pm

1 stop17h 52m

$662

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Tue 8/12

12:34 am-9:15 pm

2 stops18h 41m

Santiago Arturo Merino Benitez

Sat 8/23

11:00 am-8:21 am

1 stop23h 21m

$730

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 8/7

8:34 am-6:55 am

2 stops20h 21m

Santiago Arturo Merino Benitez

Mon 8/18

9:55 pm-6:04 pm

2 stops22h 09m

$758

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 9/6

8:22 pm-2:35 am

3 stops28h 13m

$403

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Thu 10/9

7:05 am-6:00 am

2 stops19h 55m

$436

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Sat 9/6

1:00 pm-7:05 am

1 stop16h 05m

$513

DenverSantiago

DEN - SCL

DENSCL

Denver Intl

Fri 11/21

12:59 am-7:00 am

1 stop26h 01m

$524

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Showing 1-10 of 12 results
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Best time to book a flight from Denver to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Denver with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Denver to Santiago

How far ahead should I book a flight from Denver to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Denver to Santiago. Price data was last updated on June 9, 2025.

The price you pay for your flight from Denver to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 63 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Denver to Santiago?

Currently, April is the cheapest month in which you can book a flight from Denver to Santiago (average of $752). Flying from Denver to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DEN to SCL?

Find hourly flight availability from Denver to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Denver to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 17% versus a flight in the morning.

What is the cheapest day to fly from Denver to Santiago?

Use this chart to determine the cheapest time to fly round-trip from Denver to Santiago. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Denver to Santiago flight should consider departing on Monday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Santiago by month

Plan your trip to Santiago by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Santiago ranges from 0.0 - 2.8 inches per month. June is typically the wettest month, when rainfall can reach 2.8 in. January is typically the driest time to visit Santiago when rainfall is around 0.0 in.

Temperature in Santiago by month

Plan your trip to Santiago by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Santiago, use this chart to help with planning. For those seeking warmer temperatures, January is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of June, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

8.0

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Denver to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Denver to Santiago round-trip?

    Currently priced at $615, Copa Airlines will fly you from Denver to Santiago and back. In addition to Copa Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from LATAM Airlines and Delta - these airlines can fly you to your destination from $626 and $646, respectively. Copa Airlines is currently priced 27% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Denver to Santiago one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $436. American Airlines flights start at $513 while deals on Delta start at $524 one-way.

  • Can I find deals for flights from Denver to Santiago that include hotel bookings?

    Yes. In addition to deals on Denver to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Denver to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Denver to Santiago.

  • Can I find deals for business class flights from Denver to Santiago?

    Yes. Cheapflights offers flight deals from Denver to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Denver to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Denver to Santiago (average of $752). Flying from Denver to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Denver to Santiago

See prices for flight routes from nearby airports that may be better suited for you.
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Denver to Easter Island flights
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Grand Junction to Santiago flights
Montrose to Santiago flights

Top 6 airlines flying from Denver to Santiago

Discover the top 6 airlines that operate flights from Denver to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$592Average$813FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$601Average$877FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$620Average$722FlexibilityNo cancel feeOn-time70%
DeltaCheapest$752Average$866FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$752Average$872FlexibilityNo cancel feeOn-time81%
AeromexicoCheapest$803Average$1,154FlexibilityNo cancel feeOn-timeN/A

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