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$203+ Cheap flights from Cali (CLO) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/7. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — SCL
ago. 19 — ago. 261
mar. 8/19
mar. 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez are usually found in October or September, booked 43 days in advance, depart on a Monday or Tuesday and return on a Monday

Cheap flight deals from Cali to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 14, 2025.

Round-trip from

$331
(FlightHub)

One-way from

$203
(Priceline)

Popular in

February

Cheapest in

October

Average price

$356

Good round-trip deal

$384 or less
From Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez
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One-way flight from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez
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Highest demand for flights based on searches. 8% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Price to beat on a round-trip flight from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez.
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Find flight deals from Cali to Santiago

Cheapest flights from Cali to Santiago
Explore the most affordable flight options available from Cali to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 14, 2025.

This Kiwi.com deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/221:13 pmCLO - SCL
2 stops13h 48mMultiple Airlines
dom. 8/316:10 amSCL - CLO
1 stop9h 10mMultiple Airlines
Deal found 8/14$294
This CheapOair deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/158:35 pmCLO - SCL
Nonstop5h 42mJetSMART
dom. 1/185:04 pmSCL - CLO
Nonstop5h 58mJetSMART
Deal found 8/11$317
This FlightHub deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/169:47 pmCLO - SCL
2 stops15h 13mLATAM Airlines
lun. 9/2212:25 amSCL - CLO
1 stop11h 29mLATAM Airlines
Deal found 8/12$331
This CheapOair deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/68:35 pmCLO - SCL
Nonstop5h 42mJetSMART
mié. 10/152:38 pmSCL - CLO
1 stop23h 33mJetSMART
Deal found 8/12$334
This Copa Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/2012:01 pmCLO - SCL
1 stop10h 07mCopa Airlines
mié. 9/34:11 amSCL - CLO
1 stop14h 14mCopa Airlines
Deal found 8/13$335
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/137:24 pmCLO - SCL
1 stop7h 51mAvianca
lun. 10/2012:55 amSCL - CLO
1 stop8h 40mAvianca
Deal found 8/14$336
This Trip.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/181:13 pmCLO - SCL
1 stop9h 55mMultiple Airlines
mié. 3/1112:25 amSCL - CLO
1 stop9h 01mMultiple Airlines
Deal found 8/13$337
This LATAM Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/66:16 pmCLO - SCL
1 stop18h 14mLATAM Airlines
mié. 10/154:35 pmSCL - CLO
2 stops25h 18mLATAM Airlines
Deal found 8/12$338
This Avianca deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/2712:42 pmCLO - SCL
1 stop8h 48mAvianca
lun. 9/1512:55 amSCL - CLO
1 stop8h 40mAvianca
Deal found 8/14$339
This Avianca deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/47:09 pmCLO - SCL
1 stop8h 06mAvianca
lun. 10/137:10 amSCL - CLO
1 stop9h 10mAvianca
Deal found 8/12$343
This Avianca deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 10/611:23 amCLO - SCL
1 stop10h 07mAvianca
mar. 10/1412:55 amSCL - CLO
1 stop8h 40mAvianca
Deal found 8/13$344

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
Use the filters below to find and compare flights from Cali to Santiago that are best for you.

Fly from

Cali

Fly to

Santiago

Route

Depart

Return

Price

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

jue. 9/11

10:05 pm-3:00 pm

2 stops14h 55m

Santiago Arturo Merino Benitez

jue. 9/18

4:35 pm-6:07 am

1 stop15h 32m

$331

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

lun. 10/6

7:57 pm-2:30 pm

1 stop16h 33m

Santiago Arturo Merino Benitez

mié. 10/15

4:35 pm-8:22 am

1 stop17h 47m

$331

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

lun. 10/6

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

mié. 10/15

2:38 pm-12:11 pm

1 stop23h 33m

$334

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

mié. 9/10

8:48 am-12:04 am

1 stop13h 16m

Santiago Arturo Merino Benitez

lun. 9/29

1:13 am-5:25 pm

1 stop18h 12m

$335

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

lun. 9/15

8:48 am-3:42 am

1 stop16h 54m

Santiago Arturo Merino Benitez

mar. 9/30

5:11 am-2:21 pm

1 stop11h 10m

$335

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

vie. 9/12

8:48 am-3:24 am

1 stop16h 36m

Santiago Arturo Merino Benitez

sáb. 9/27

1:13 am-5:25 pm

1 stop18h 12m

$335

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

vie. 9/5

12:01 pm-10:40 pm

1 stop9h 39m

Santiago Arturo Merino Benitez

sáb. 10/4

1:24 am-2:25 pm

1 stop15h 01m

$335

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

mar. 8/26

12:01 pm-11:08 pm

1 stop10h 07m

Santiago Arturo Merino Benitez

vie. 9/26

5:11 am-5:25 pm

1 stop14h 14m

$335

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

dom. 9/14

8:48 am-3:42 am

1 stop16h 54m

$204

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

vie. 9/12

12:01 pm-3:24 am

1 stop13h 23m

$204

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 16 results
1
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Best time to book a flight from Cali to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santiago

How far ahead should I book a flight from Cali to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Santiago. Price data was last updated on August 8, 2025.

To ensure you get the cheapest price possible for a flight from Cali to Santiago, you should look to book at least 43 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cali to Santiago?

Currently, April is the cheapest month in which you can book a flight from Cali to Santiago (average of $752). Flying from Cali to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLO to SCL?

Find hourly flight availability from Cali to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 14, 2025.

When flying from Cali to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 44% versus a flight in the evening.

How much does it cost to fly round-trip from Cali to Santiago?

What’s the top layover airport for flights from Cali to Santiago?

Share of 1-stop round-trip flights from Cali to Santiago chosen by Cheapflights users in the past 12 months, using the same layover each way.

Panama City (PTY) – chosen by Cheapflights users on 67% of 1-stop itineraries from Cali to Santiago on Cheapflights.

What’s the cheapest layover airport for flights from Cali to Santiago?

Average round-trip fare for 1-stop flights from Cali to Santiago, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Panama City (PTY) is the most affordable 1-stop option, with an average round-trip price of $327.

What’s the fastest layover option from Cali to Santiago?

Shortest average travel time for 1-stop one-way flights from Cali to Santiago, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Bogotá (BOG) have the shortest average one-way travel time for 1-stop routes: 7h 51m.

Which airport typically offers the quickest layover for flights from Cali to Santiago?

Average layover duration for 1-stop one-way flights from Cali to Santiago, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Bogotá (BOG) offer the fastest connection on this route, with an average layover time of 1h 35m.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated agosto 14, 2025.
Get a feel of what it's like to fly with Copa Airlines, Avianca, and JetSMART from Cali to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,507 reviews

Crew

8.1

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Copa Airlines
7.5
Good
1,507 reviews
Copa Airlines
7.5
Good
1,507 reviews

Crew

8.1

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
Avianca
6.7
Okay
2,399 reviews
Copa Airlines
7.5
Good
1,507 reviews

Crew

8.1

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.
JetSMART
6.5
Okay
213 reviews
Copa Airlines
7.5
Good
1,507 reviews

Crew

8.1

Boarding

7.8

Food

6.8

Comfort

7.4

Entertainment

6.8

Overall

7.5

Reviews

1 / 20
4.0
Okay

Paul,Jun 2025

PTY - MIA

The boarding process was terrible. No one followed the group numbers. Everyone got up and stood in the tiles upon landing. People kept getting up during the meal and beverage service to go the bathrooms, the crew had to go back and forth in the isles, the service took forever.

Related info for your journey

Find useful and relevant information for your journey from Cali to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Cali to Santiago flight route?

    This flight path from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Cali to Santiago round-trip?

    Cheapflights users have booked flights from Cali to Santiago round-trip from $230. Other airlines that can offer you cheap pricing are Copa Airlines, from $257, and JetSMART, from $266. Users have found that Avianca is 38% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Cali to Santiago one-way?

    For one-way options, check prices for Avianca. According to our data, you can fly for as low as $203. Users have also found prices from $204 and $216 on Copa Airlines and JetSMART, respectively.

  • What are the cheapest flights from Cali to Santiago?

    Looking at all options, your cheapest flight can be booked for $356. While the most popular route (Cali Alfonso B. Aragon Intl - Santiago Arturo Merino Benitez) can be booked for $334 on average our data indicates $393 when flying from Cali to Santiago.

  • Can I find deals for flights from Cali to Santiago that include hotel bookings?

    Yes. In addition to deals on Cali to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santiago.

  • Can I find deals for business class flights from Cali to Santiago?

    Yes. Cheapflights offers flight deals from Cali to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Santiago?

    Currently, April is the cheapest month in which you can book a flight from Cali to Santiago (average of $752). Flying from Cali to Santiago in December is currently the most expensive (average of $1,098). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Cali to Santiago

Discover the top 3 airlines that operate flights from Cali to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$230Average$394FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$257Average$354FlexibilityNo cancel feeOn-time70%
JetSMARTCheapest$266Average$435FlexibilityNo cancel feeOn-timeN/A

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