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$192+ Cheap flights from Cali (CLO) to Santiago (SCL)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/15. Fares are subject to change and may not be available on all flights or dates of travel.
CLO — SCL
Jan 29 — Feb 51
Thu 1/29
Thu 2/5
1 adult, Economy
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Find cheap flights from Cali to Santiago with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

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3. Compare prices and book

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Cheapflights Tip: The best prices from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez are usually found in May or June, booked 57 days in advance, depart on a Thursday or Tuesday and return on a Thursday

Cheap flight deals from Cali to Santiago

Cheapest flights from Cali to Santiago
Explore the most affordable flight options available from Cali to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 30, 2025.

This Avianca deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:05 pmCLO - SCL
1 stop8h 25mAvianca
Thu 1/294:25 pmSCL - CLO
1 stop9h 15mAvianca
Deal found 12/28$398
This JetSMART deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/299:09 pmCLO - SCL
Nonstop5h 42mJetSMART
Sat 2/143:37 pmSCL - CLO
Nonstop5h 58mJetSMART
Deal found 12/27$403
This JetSMART deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:35 pmCLO - SCL
Nonstop5h 42mJetSMART
Mon 2/93:37 pmSCL - CLO
Nonstop5h 58mJetSMART
Deal found 12/29$406
This LATAM Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/292:50 pmCLO - SCL
2 stops13h 35mLATAM Airlines
Wed 1/284:35 amSCL - CLO
2 stops19h 38mLATAM Airlines
Deal found 12/28$417
This JetSMART deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:50 pmCLO - SCL
Nonstop5h 42mJetSMART
Sun 2/15:00 amSCL - CLO
Nonstop5h 58mJetSMART
Deal found 12/29$449
This JetSMART deal was found by Cheapflights users on 12/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2710:35 pmCLO - SCL
Nonstop5h 42mJetSMART
Tue 1/279:29 pmSCL - CLO
2 stops36h 04mJetSMART
Deal found 12/27$491
This JetSMART deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure JetSMART is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:35 pmCLO - SCL
Nonstop5h 42mJetSMART
Fri 1/162:23 pmSCL - CLO
1 stop23h 48mJetSMART
Deal found 12/30$513

Find flight deals from Cali to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Cali (CLO) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 30, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$304
(JetSMART)

One-way from

$192
(JetSMART)

Popular in

March

Cheapest in

May

Average price

$384

Good round-trip deal

$343 or less

Good one-way deal

$245 or less
Provider with most accurate pricing for Cali Alfonso B. Aragon Intl-Santiago Arturo Merino Benitez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Cali Alfonso B. Aragon Intl-Santiago Arturo Merino Benitez flights.
Search Deals
From Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez
Search Deals
One-way flight from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez
Search Deals
Highest demand for flights based on searches. 2% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez.
Search Deals
Price to beat on a one-way flight from Cali Alfonso B. Aragon Intl to Santiago Arturo Merino Benitez.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cali to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
Use the filters below to find and compare flights from Cali to Santiago that are best for you.

Fly from

Cali

Fly to

Santiago

Route

Depart

Return

Price

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 6/1

9:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 6/15

3:33 pm-8:35 pm

Nonstop6h 02m

$304

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 3/23

8:40 pm-4:22 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 4/6

3:42 pm-8:40 pm

Nonstop5h 58m

$304

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 4/13

9:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Mon 4/20

3:30 pm-8:35 pm

Nonstop6h 05m

$304

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Sun 5/17

9:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 5/24

3:33 pm-8:35 pm

Nonstop6h 02m

$304

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Tue 4/21

2:08 pm-2:30 pm

1 stop23h 22m

Santiago Arturo Merino Benitez

Sun 4/26

3:30 pm-8:35 pm

Nonstop6h 05m

$317

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 3/16

8:40 pm-4:22 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Fri 4/10

9:54 am-1:12 pm

1 stop28h 18m

$317

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Thu 5/21

2:11 pm-2:03 pm

1 stop22h 52m

Santiago Arturo Merino Benitez

Mon 5/25

1:11 am-6:55 am

1 stop30h 44m

$350

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Fri 3/20

8:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 5/31

3:19 pm-1:11 pm

2 stops46h 52m

$350

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Thu 3/12

1:09 pm-8:01 pm

1 stop28h 52m

Santiago Arturo Merino Benitez

Fri 5/15

3:33 pm-8:35 pm

Nonstop6h 02m

$352

CaliSantiago

CLO - SCL

CLOSCL

Cali Alfonso B. Aragon Intl

Mon 4/13

9:35 pm-4:17 am

Nonstop5h 42m

Santiago Arturo Merino Benitez

Sun 4/26

3:33 pm-8:35 pm

Nonstop6h 02m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Showing 1-10 of 18 results
1
2

Compare providers for flights from Cali to Santiago

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cali to Santiago in December.
ProviderPrice AccuracyTrust Score*
eDreamsPrice Accuracy3 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
MytripPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Cali-Santiago flights, users find the pricing of Mytrip to be most consistent on Cheapflights vs. Mytrip Users can find the same prices on Cali-Santiago flight deals on Cheapflights vs. Mytrip >95% of the time. Price accuracy is based on data collected from Cali-Santiago flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cali-Santiago flights, Cheapflights users trust Mytrip the most. Mytrip has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cali-Santiago flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cali to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cali with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cali to Santiago

How far ahead should I book a flight from Cali to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Cali to Santiago. Price data was last updated on December 26, 2025.

To ensure you get the cheapest price possible for a flight from Cali to Santiago, you should look to book at least 57 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cali to Santiago?

Currently, May is the cheapest month in which you can book a flight from Cali to Santiago (average of $153). Flying from Cali to Santiago in November is currently the most expensive (average of $218). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLO to SCL?

Find hourly flight availability from Cali to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 30, 2025.

When flying from Cali to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Santiago

Get insights into the airlines that provide service to Santiago. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Santiago. Reviews last updated December 30, 2025.
Get a feel of what it's like to fly with Avianca and JetSMART from Cali to Santiago by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Avianca
6.6
Okay
2,491 reviews

Entertainment

5.4

Overall

6.6

Comfort

6.3

Food

5.1

Crew

7.2

Boarding

6.9

Reviews

1 / 20
6.0
Good

Adrian,Sep 2025

MDE - CUN

It was a decent flight. No extras like a meal or a snack. But would do it again as the pricing was right.
Avianca
6.6
Okay
2,491 reviews
Avianca
6.6
Okay
2,491 reviews

Entertainment

5.4

Overall

6.6

Comfort

6.3

Food

5.1

Crew

7.2

Boarding

6.9

Reviews

1 / 20
6.0
Good

Adrian,Sep 2025

MDE - CUN

It was a decent flight. No extras like a meal or a snack. But would do it again as the pricing was right.
JetSMART
6.6
Okay
258 reviews
Avianca
6.6
Okay
2,491 reviews

Entertainment

5.4

Overall

6.6

Comfort

6.3

Food

5.1

Crew

7.2

Boarding

6.9

Reviews

1 / 20
6.0
Good

Adrian,Sep 2025

MDE - CUN

It was a decent flight. No extras like a meal or a snack. But would do it again as the pricing was right.

Related info for your journey

Find useful and relevant information for your journey from Cali to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cali to Santiago?

    JetSMART can get you from Cali to Santiago in just under 5h 42m. Your travel time will be generally consistent. Airlines will cover a distance of 2576 mi. All flights are typically nonstop.

  • What are the cheapest airlines flying from Cali to Santiago round-trip?

    Cheapflights users have booked flights from Cali to Santiago round-trip from $227. Another airline that can offer you cheap pricing is JetSMART. Users have found that Avianca is 40% cheaper than the other options available to this destination.

  • What are the cheapest flights from Cali to Santiago?

    Looking at all options, your cheapest flight can be booked for $165. While the most popular route (Cali Alfonso B. Aragon Intl - Santiago Arturo Merino Benitez) can be booked for $475 on average, our data indicates $310 when flying from Cali to Santiago.

  • Can I find deals for flights from Cali to Santiago that include hotel bookings?

    Yes. In addition to deals on Cali to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santiago.

  • Can I find deals for business class flights from Cali to Santiago?

    Yes. Cheapflights offers flight deals from Cali to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Cali to Santiago (average of $153). Flying from Cali to Santiago in November is currently the most expensive (average of $218). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Cali to Santiago

Discover the top 2 airlines that operate flights from Cali to Santiago. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$230Average$391FlexibilityNo cancel feeOn-time71%
JetSMARTCheapest$286Average$417FlexibilityNo cancel feeOn-timeN/A

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