$384+ Cheap flights from Sicily to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
CTA — SFO
Jun 16 — Jun 231
Round-trip
1 adult, Economy
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Cheapest flights from Sicily to San FranciscoExplore the most affordable flight options available from Sicily to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.
Explore the most affordable flight options available from Sicily to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 17, 2026.
This lol.travel deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:30 pm
PMO
- SFO
1 stop25h 45m
ITA Airways
Tue 5/263:15 pm
SFO
- PMO
1 stop18h 05m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$576
This Gotogate deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:10 am
PMO
- SFO
1 stop16h 05m
ITA Airways
Sat 9/193:15 pm
SFO
- PMO
1 stop15h 05m
ITA Airways
Deal found 5/16![ITA Airways logo]()
$578
This ITA Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am
CTA
- SFO
1 stop16h 05m
ITA Airways
Sat 11/283:05 pm
SFO
- CTA
1 stop23h 15m
ITA Airways
Deal found 5/16![ITA Airways logo]()
$603
This Expedia deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am
PMO
- SFO
1 stop16h 05m
ITA Airways
Sun 9/203:15 pm
SFO
- PMO
1 stop20h 50m
ITA Airways
Deal found 5/16![ITA Airways logo]()
$624
This ITA Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:20 am
PMO
- SFO
2 stops20h 06m
Multiple Airlines
Sun 9/203:15 pm
SFO
- PMO
1 stop14h 10m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$628
This ITA Airways deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:30 pm
CTA
- SFO
1 stop29h 45m
ITA Airways
Mon 10/193:15 pm
SFO
- CTA
1 stop15h 30m
ITA Airways
Deal found 5/15![ITA Airways logo]()
$653
This ITA Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:20 am
PMO
- SFO
2 stops20h 06m
Multiple Airlines
Sat 9/193:15 pm
SFO
- PMO
1 stop14h 10m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$657
This ITA Airways deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:30 pm
CTA
- SFO
1 stop24h 45m
ITA Airways
Mon 10/53:15 pm
SFO
- CTA
1 stop23h 00m
ITA Airways
Deal found 5/11![ITA Airways logo]()
$707
This ITA Airways deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:15 am
SUF
- SFO
1 stop16h 00m
ITA Airways
Tue 9/83:15 pm
SFO
- SUF
1 stop14h 20m
ITA Airways
Deal found 5/13![ITA Airways logo]()
$708
This ITA Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:30 pm
CTA
- SFO
1 stop29h 45m
ITA Airways
Tue 8/183:15 pm
SFO
- CTA
1 stop15h 30m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$716
This ITA Airways deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:15 pm
SUF
- SFO
1 stop27h 00m
ITA Airways
Mon 10/193:15 pm
SFO
- SUF
1 stop22h 45m
ITA Airways
Deal found 5/15![ITA Airways logo]()
$732
This ITA Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:25 am
REG
- SFO
1 stop15h 50m
ITA Airways
Mon 9/283:15 pm
SFO
- REG
1 stop14h 15m
ITA Airways
Deal found 5/16![ITA Airways logo]()
$732
Best flights from Sicily to San FranciscoDiscover carefully curated flight deals from Sicily to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 17, 2026.
Discover carefully curated flight deals from Sicily to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 17, 2026.
This Expedia deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:10 am
PMO
- SFO
1 stop16h 05m
ITA Airways
Sun 9/203:15 pm
SFO
- PMO
1 stop20h 50m
ITA Airways
Deal found 5/16![ITA Airways logo]()
$624
This ITA Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:20 am
PMO
- SFO
2 stops20h 06m
Multiple Airlines
Sun 9/203:15 pm
SFO
- PMO
1 stop14h 10m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$628
This British Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:50 pm
PMO
- SFO
1 stop27h 00m
British Airways
Tue 10/64:35 pm
SFO
- PMO
1 stop33h 35m
British Airways
Deal found 5/16![British Airways logo]()
$765
This Turkish Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:25 am
CTA
- SFO
1 stop34h 25m
Turkish Airlines
Tue 6/2312:55 pm
SFO
- CTA
1 stop44h 30m
Turkish Airlines
Deal found 5/13![Turkish Airlines logo]()
$821
This Air Canada deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/189:00 am
CTA
- SFO
2 stops33h 09m
Air Canada
Wed 7/110:47 pm
SFO
- CTA
2 stops25h 08m
Air Canada
Deal found 5/16![Air Canada logo]()
$862
This United Airlines deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:25 am
REG
- SFO
2 stops23h 05m
United Airlines
Mon 9/288:10 am
SFO
- REG
2 stops21h 20m
United Airlines
Deal found 5/15![United Airlines logo]()
$1,103
This ITA Airways deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:30 pm
CTA
- SFO
1 stop29h 45m
ITA Airways
Mon 10/193:15 pm
SFO
- CTA
1 stop15h 30m
ITA Airways
Deal found 5/15![ITA Airways logo]()
$653
This ITA Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/37:20 am
PMO
- SFO
2 stops20h 06m
Multiple Airlines
Sat 9/193:15 pm
SFO
- PMO
1 stop14h 10m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$657
This ITA Airways deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/19:30 pm
CTA
- SFO
1 stop24h 45m
ITA Airways
Mon 10/53:15 pm
SFO
- CTA
1 stop23h 00m
ITA Airways
Deal found 5/11![ITA Airways logo]()
$707
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/159:10 pm
CTA
- SFO
2 stops26h 20m
Multiple Airlines
Sun 6/284:30 pm
SFO
- CTA
2 stops19h 05m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$770
This ITA Airways deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:15 am
SUF
- SFO
1 stop16h 00m
ITA Airways
Tue 9/83:15 pm
SFO
- SUF
1 stop14h 20m
ITA Airways
Deal found 5/13![ITA Airways logo]()
$708
This ITA Airways deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:15 pm
SUF
- SFO
1 stop27h 00m
ITA Airways
Mon 10/193:15 pm
SFO
- SUF
1 stop22h 45m
ITA Airways
Deal found 5/15![ITA Airways logo]()
$732
This ITA Airways deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:25 am
REG
- SFO
1 stop15h 50m
ITA Airways
Mon 9/283:15 pm
SFO
- REG
1 stop14h 15m
ITA Airways
Deal found 5/16![ITA Airways logo]()
$732
This ITA Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
CTA
- SFO
1 stop16h 15m
ITA Airways
Tue 8/183:15 pm
SFO
- CTA
2 stops17h 40m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$733
This Gotogate deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:00 am
CTA
- SFO
1 stop16h 15m
ITA Airways
Wed 7/13:15 pm
SFO
- CTA
1 stop35h 45m
ITA Airways
Deal found 5/16![ITA Airways logo]()
$863
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:25 am
REG
- SFO
1 stop15h 50m
Multiple Airlines
Fri 6/51:00 pm
SFO
- REG
2 stops24h 55m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$1,293
Last-minute flights from Sicily to San FranciscoDiscover last-minute flight deals from Sicily to San Francisco. Data last updated May 17, 2026 and is based on user searches.
Discover last-minute flight deals from Sicily to San Francisco. Data last updated May 17, 2026 and is based on user searches.
This lol.travel deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/218:30 pm
PMO
- SFO
1 stop25h 45m
ITA Airways
Tue 5/263:15 pm
SFO
- PMO
1 stop18h 05m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$576
This United Airlines deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:45 am
PMO
- SFO
2 stops22h 11m
United Airlines
Thu 5/2811:59 pm
SFO
- PMO
1 stop22h 16m
United Airlines
Deal found 5/16![United Airlines logo]()
$813
This ITA Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/246:00 am
CTA
- SFO
1 stop16h 15m
ITA Airways
Tue 8/183:15 pm
SFO
- CTA
1 stop14h 25m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$835
This ITA Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/274:30 pm
CTA
- SFO
1 stop29h 45m
ITA Airways
Tue 8/183:15 pm
SFO
- CTA
1 stop15h 30m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$716
This British Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/279:55 pm
CTA
- SFO
1 stop24h 55m
British Airways
Mon 8/244:35 pm
SFO
- CTA
1 stop17h 20m
British Airways
Deal found 5/14![British Airways logo]()
$762
This ITA Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
CTA
- SFO
1 stop16h 15m
ITA Airways
Tue 8/183:15 pm
SFO
- CTA
2 stops17h 40m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$733
This ITA Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:00 am
CTA
- SFO
1 stop16h 15m
ITA Airways
Mon 8/243:15 pm
SFO
- CTA
1 stop15h 30m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$845
This ITA Airways deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
CTA
- SFO
1 stop16h 15m
ITA Airways
Tue 8/183:15 pm
SFO
- CTA
1 stop14h 25m
ITA Airways
Deal found 5/14![ITA Airways logo]()
$812
This Mytrip deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/86:15 am
CTA
- SFO
2 stops21h 45m
Multiple Airlines
Tue 6/232:40 pm
SFO
- CTA
2 stops25h 35m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$770
This KLM deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:35 pm
CTA
- SFO
1 stop22h 10m
KLM
Sun 6/1411:57 pm
SFO
- CTA
1 stop22h 58m
KLM
Deal found 5/12![KLM logo]()
$794
This Turkish Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Turkish Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/89:25 am
CTA
- SFO
1 stop34h 25m
Turkish Airlines
Tue 6/2312:55 pm
SFO
- CTA
1 stop44h 30m
Turkish Airlines
Deal found 5/13![Turkish Airlines logo]()
$821
This lol.travel deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:25 am
PMO
- SFO
1 stop34h 25m
Turkish Airlines
Sun 6/216:45 pm
SFO
- PMO
1 stop38h 50m
Turkish Airlines
Deal found 5/13![Turkish Airlines logo]()
$908
One-way flights from Sicily to San FranciscoSearch for one-way flight options from Sicily to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 17, 2026.
Search for one-way flight options from Sicily to San Francisco. Find affordable one-way fares based on user searches. Data last updated May 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:40 pm
CTA
- SFO
1 stop30h 10m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:00 pm
CTA
- SFO
3 stops53h 50m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$429
This Trip.com deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:10 pm
CTA
- SFO
2 stops48h 25m
Multiple Airlines
Deal found 5/15![Multiple Airlines logo]()
$448
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:25 pm
PMO
- SFO
3 stops50h 05m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$462
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/265:45 am
CTA
- SFO
3 stops41h 45m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$477
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:15 pm
CTA
- SFO
3 stops36h 35m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$507
This Expedia deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:55 pm
CTA
- SFO
2 stops26h 55m
Iberia
Deal found 5/16![Iberia logo]()
$523
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/2510:05 am
PMO
- SFO
3 stops39h 35m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$524
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:00 am
CTA
- SFO
3 stops41h 50m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$527
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/319:30 pm
PMO
- SFO
3 stops47h 30m
Multiple Airlines
Deal found 5/16![Multiple Airlines logo]()
$531
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:30 am
PMO
- SFO
3 stops43h 10m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$547
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/2910:45 pm
PMO
- SFO
3 stops50h 55m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$559
Find flight deals from Sicily to San Francisco
Keep the following information in mind while searching for Sicily to San Francisco flight deals. Data was last updated May 17, 2026.
Round-trip from | $578 (Gotogate) |
|---|---|
One-way from | $384 (Kiwi.com) |
Popular in | November |
Cheapest in | September |
Average price | $638 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sicily to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
Use the filters below to find and compare flights from Sicily to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PalermoSan Francisco
PMO - SFO
PMOSFO
Palermo Punta Raisi
Wed 9/2
6:10 am-1:15 pm
1 stop16h 05m
San Francisco
Sun 9/20
3:15 pm-9:05 pm
1 stop20h 50m
$624
PalermoSan Francisco
PMO - SFO
PMOSFO
Palermo Punta Raisi
Wed 9/2
7:20 am-6:26 pm
2 stops20h 06m
San Francisco
Sun 9/20
3:15 pm-2:25 pm
1 stop14h 10m
$628
CataniaSan Francisco
CTA - SFO
CTASFO
Catania Fontanarossa
Thu 10/15
4:30 pm-1:15 pm
1 stop29h 45m
San Francisco
Mon 10/19
3:15 pm-3:45 pm
1 stop15h 30m
$653
PalermoSan Francisco
PMO - SFO
PMOSFO
Palermo Punta Raisi
Thu 9/3
7:20 am-6:26 pm
2 stops20h 06m
San Francisco
Sat 9/19
3:15 pm-2:25 pm
1 stop14h 10m
$657
CataniaSan Francisco
CTA - SFO
CTASFO
Catania Fontanarossa
Thu 10/1
9:30 pm-1:15 pm
1 stop24h 45m
San Francisco
Mon 10/5
3:15 pm-11:15 pm
1 stop23h 00m
$707
Lamezia TermeSan Francisco
SUF - SFO
SUFSFO
Lamezia Terme Intl
Fri 9/4
6:15 am-1:15 pm
1 stop16h 00m
San Francisco
Tue 9/8
3:15 pm-2:35 pm
1 stop14h 20m
$708
Lamezia TermeSan Francisco
SUF - SFO
SUFSFO
Lamezia Terme Intl
Thu 10/15
7:15 pm-1:15 pm
1 stop27h 00m
San Francisco
Mon 10/19
3:15 pm-11:00 pm
1 stop22h 45m
$732
Quickest round-trip
Reggio CalabriaSan Francisco
REG - SFO
REGSFO
Reggio Calabria Tito Menniti
Thu 9/24
6:25 am-1:15 pm
1 stop15h 50m
San Francisco
Mon 9/28
3:15 pm-2:30 pm
1 stop14h 15m
$732
CataniaSan Francisco
CTA - SFO
CTASFO
Catania Fontanarossa
Thu 5/28
6:00 am-1:15 pm
1 stop16h 15m
San Francisco
Tue 8/18
3:15 pm-5:55 pm
2 stops17h 40m
$733
PalermoSan Francisco
PMO - SFO
PMOSFO
Palermo Punta Raisi
Fri 10/2
7:50 pm-1:50 pm
1 stop27h 00m
San Francisco
Tue 10/6
4:35 pm-11:10 am
1 stop33h 35m
$765
Showing 1-10 of 42 resultsSorted by cheapest first
Best time to book a flight from Sicily to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sicily with our price prediction graph.
PMO-SFO
CTA-SFO
REG-SFO
SUF-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Sicily to San Francisco
ITSI-SFO
PMO-SFO
CTA-SFO
REG-SFO
SUF-SFO
How much does it cost to fly round-trip from Sicily to San Francisco?
Related info for your journey
Find useful and relevant information for your journey from Sicily to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Cruz
Santa Clara
Fairfield
Rancho Cordova
San Bruno
Watsonville
San Ramon
Vacaville
Roseville
San Carlos
Redwood City
Sunnyvale
Turlock
Vallejo
San Lorenzo
Davis
Emeryville
Manteca
Elk Grove
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Complete your trip
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Sicily and San Francisco flights
Browse other Sicily and San Francisco flight options. Last updated on May 17, 2026.
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Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 17, 2026.
Sicily to San Francisco flights
Consider these flights traveling from Sicily to San Francisco.
Top airline flying from Sicily to San Francisco
Discover the top airline that operate flights from Sicily to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$710 | Average$990 | FlexibilityNo cancel fee | On-time76% |