$419+ Cheap flights from Sicily to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
CTA — SFO
Nov 25 — Dec 21
Round-trip
1 adult, Economy
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Find cheap flights from Sicily to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Sicily to San Francisco
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Best
Last-minute
One-way
Cheapest flights from Sicily to San FranciscoExplore the most affordable flight options available from Sicily to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
Explore the most affordable flight options available from Sicily to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 26, 2026.
This lastminute.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
1 stop16h 00m
Tue 11/103:05 pm -
1 stop14h 20m
Deal found 10/21![ITA Airways logo]()
$578
This lol.travel deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
2 stops23h 31m
Tue 12/88:40 am -
2 stops21h 00m
Deal found 10/25![Multiple Airlines logo]()
$583
This oojo deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
1 stop16h 00m
Sat 11/283:05 pm -
1 stop14h 20m
Deal found 10/24![ITA Airways logo]()
$591
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:10 am -
1 stop23h 05m
Sun 11/2211:05 pm -
1 stop24h 50m
Deal found 10/24![Delta logo]()
$598
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:55 am -
1 stop19h 43m
Mon 11/27:00 am -
1 stop16h 55m
Deal found 10/21![Delta logo]()
$599
This ITA Airways deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop16h 10m
Sun 1/103:05 pm -
1 stop14h 35m
Deal found 10/23![ITA Airways logo]()
$602
This Expedia deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:30 pm -
2 stops38h 56m
Mon 11/27:00 am -
1 stop16h 55m
Deal found 10/21![Air France logo]()
$608
This Expedia deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:10 pm -
1 stop28h 35m
Sat 12/127:00 am -
1 stop17h 10m
Deal found 10/23![KLM logo]()
$623
This British Airways deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:40 pm -
2 stops41h 02m
Tue 11/101:30 pm -
2 stops37h 20m
Deal found 10/21![British Airways logo]()
$624
This KLM deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
2 stops22h 56m
Tue 11/107:00 am -
2 stops22h 25m
Deal found 10/26![Multiple Airlines logo]()
$625
This KLM deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:55 pm -
1 stop24h 50m
Sun 12/137:00 am -
1 stop16h 55m
Deal found 10/22![KLM logo]()
$629
This Expedia deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:55 am -
1 stop20h 55m
Tue 12/810:25 pm -
1 stop25h 30m
Deal found 10/25![KLM logo]()
$630
Best flights from Sicily to San FranciscoDiscover carefully curated flight deals from Sicily to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
Discover carefully curated flight deals from Sicily to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 26, 2026.
This lol.travel deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/59:10 am -
2 stops21h 23m
Sun 2/148:13 am -
2 stops26h 42m
Deal found 10/21![Air Canada logo]()
$553
This Expedia deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/146:55 pm -
2 stops36h 08m
Sat 4/244:35 pm -
1 stop19h 25m
Deal found 10/21![Multiple Airlines logo]()
$556
This Expedia deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/59:10 am -
1 stop16h 20m
Sun 2/147:25 pm -
1 stop15h 30m
Deal found 10/21![SWISS logo]()
$577
This lol.travel deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
1 stop16h 00m
Tue 11/103:05 pm -
1 stop33h 15m
Deal found 10/22![ITA Airways logo]()
$585
This Expedia deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/108:45 pm -
1 stop24h 00m
Thu 12/177:00 am -
1 stop16h 55m
Deal found 10/26![KLM logo]()
$623
This British Airways deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:40 pm -
2 stops41h 02m
Tue 11/101:30 pm -
2 stops37h 20m
Deal found 10/21![British Airways logo]()
$624
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:55 am -
1 stop19h 02m
Tue 12/157:00 am -
1 stop16h 55m
Deal found 10/24![Delta logo]()
$630
This Expedia deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
2 stops26h 59m
Sat 12/127:00 am -
1 stop17h 10m
Deal found 10/23![Air France logo]()
$640
This United Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/122:20 pm -
1 stop18h 37m
Mon 11/168:15 am -
1 stop19h 05m
Deal found 10/25![United Airlines logo]()
$882
This lol.travel deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:00 am -
2 stops23h 31m
Tue 12/88:40 am -
2 stops21h 00m
Deal found 10/25![Multiple Airlines logo]()
$583
This oojo deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
1 stop16h 00m
Sat 11/283:05 pm -
1 stop14h 20m
Deal found 10/24![ITA Airways logo]()
$591
This KLM deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:55 pm -
1 stop24h 50m
Sun 12/137:00 am -
1 stop16h 55m
Deal found 10/22![KLM logo]()
$629
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:55 am -
1 stop20h 55m
Sat 12/127:00 am -
2 stops19h 50m
Deal found 10/23![Delta logo]()
$632
This ITA Airways deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:00 am -
1 stop16h 10m
Sun 1/103:05 pm -
2 stops23h 25m
Deal found 10/23![ITA Airways logo]()
$618
This KLM deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
2 stops22h 56m
Tue 11/107:00 am -
2 stops22h 25m
Deal found 10/26![Multiple Airlines logo]()
$625
This KLM deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
2 stops23h 38m
Thu 12/177:00 am -
1 stop16h 55m
Deal found 10/26![Multiple Airlines logo]()
$639
This United Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:20 pm -
1 stop18h 37m
Tue 11/103:00 pm -
1 stop36h 20m
Deal found 10/26![United Airlines logo]()
$882
This Booking.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:50 pm -
3 stops30h 15m
Sat 11/284:35 pm -
2 stops22h 40m
Deal found 10/24![Multiple Airlines logo]()
$835
Last-minute flights from Sicily to San FranciscoDiscover last-minute flight deals from Sicily to San Francisco. Data last updated October 26, 2026 and is based on user searches.
Discover last-minute flight deals from Sicily to San Francisco. Data last updated October 26, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3010:55 am -
1 stop19h 43m
Mon 11/27:00 am -
1 stop16h 55m
Deal found 10/21![Delta logo]()
$599
This Expedia deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:30 pm -
2 stops38h 56m
Mon 11/27:00 am -
1 stop16h 55m
Deal found 10/21![Air France logo]()
$608
This Air France deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/210:05 am -
2 stops22h 51m
Mon 11/98:00 am -
2 stops18h 50m
Deal found 10/26![Air France logo]()
$635
This lastminute.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
1 stop16h 00m
Tue 11/103:05 pm -
1 stop14h 20m
Deal found 10/21![ITA Airways logo]()
$578
This oojo deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
1 stop16h 00m
Sat 11/283:05 pm -
1 stop14h 20m
Deal found 10/24![ITA Airways logo]()
$591
This British Airways deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:40 pm -
2 stops41h 02m
Tue 11/101:30 pm -
2 stops37h 20m
Deal found 10/21![British Airways logo]()
$624
This KLM deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:10 am -
2 stops22h 56m
Tue 11/107:00 am -
2 stops22h 25m
Deal found 10/26![Multiple Airlines logo]()
$625
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/811:10 am -
1 stop23h 05m
Sun 11/2211:05 pm -
1 stop24h 50m
Deal found 10/24![Delta logo]()
$598
This KLM deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/87:55 pm -
1 stop24h 50m
Sun 11/226:00 am -
2 stops17h 55m
Deal found 10/24![Multiple Airlines logo]()
$745
This Air France deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air France is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
2 stops21h 17m
Sun 11/226:00 am -
2 stops17h 55m
Deal found 10/24![Air France logo]()
$761
This Expedia deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/88:40 pm -
2 stops33h 53m
Sat 11/214:40 pm -
3 stops38h 00m
Deal found 10/22![Multiple Airlines logo]()
$896
This Expedia deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/86:00 am -
2 stops25h 59m
Sat 11/216:00 am -
2 stops18h 10m
Deal found 10/23![Air France logo]()
$915
One-way flights from Sicily to San FranciscoSearch for one-way flight options from Sicily to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
Search for one-way flight options from Sicily to San Francisco. Find affordable one-way fares based on user searches. Data last updated October 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1711:50 am -
2 stops35h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:25 pm -
3 stops50h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$442
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/184:50 pm -
3 stops56h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$451
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/191:45 pm -
3 stops58h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$463
This Booking.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/219:35 am -
1 stop39h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Turkish Airlines logo]()
$640
This oojo deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:45 pm -
1 stop30h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Turkish Airlines logo]()
$640
This oojo deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:10 pm -
1 stop30h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Turkish Airlines logo]()
$643
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2810:40 pm -
3 stops52h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Multiple Airlines logo]()
$726
This FlightHub deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/289:35 am -
1 stop63h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/26![Turkish Airlines logo]()
$845
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/39:15 pm -
3 stops46h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$912
Find flight deals from Sicily to San Francisco
Keep the following information in mind while searching for Sicily to San Francisco flight deals. Data was last updated October 26, 2026.
Round-trip from | $553 (lol.travel) |
|---|---|
One-way from | $419 (Kiwi.com) |
Popular in | May |
Cheapest in | September |
Average price | $666 |
Cheapflights Fare Finder
Customize your flight search to find flights from Sicily to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
Use the filters below to find and compare flights from Sicily to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Wed 11/18
4:50 pm-4:05 pm
3 stops56h 15m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$451
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Tue 11/17
3:20 pm-2:45 pm
3 stops32h 25m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$490
CataniaSan Francisco
CTA Catania Fontanarossa - SFO San Francisco
CTASFO
Catania Fontanarossa
Fri 2/5
9:10 am-9:33 pm
2 stops21h 23m
San Francisco
Sun 2/14
8:13 am-7:55 pm
2 stops26h 42m
$553
CataniaSan Francisco
CTA Catania Fontanarossa - SFO San Francisco
CTASFO
Catania Fontanarossa
Wed 4/14
6:55 pm-10:03 pm
2 stops36h 08m
San Francisco
Sat 4/24
4:35 pm-9:00 pm
1 stop19h 25m
$556
CataniaSan Francisco
CTA Catania Fontanarossa - SFO San Francisco
CTASFO
Catania Fontanarossa
Fri 2/5
9:10 am-4:30 pm
1 stop16h 20m
San Francisco
Sun 2/14
7:25 pm-7:55 pm
1 stop15h 30m
$577
CataniaSan Francisco
CTA Catania Fontanarossa - SFO San Francisco
CTASFO
Catania Fontanarossa
Sat 12/5
6:00 am-8:31 pm
2 stops23h 31m
San Francisco
Tue 12/8
8:40 am-2:40 pm
2 stops21h 00m
$583
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 11/5
6:10 am-1:10 pm
1 stop16h 00m
San Francisco
Tue 11/10
3:05 pm-9:20 am
1 stop33h 15m
$585
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 11/5
6:10 am-1:10 pm
1 stop16h 00m
San Francisco
Sat 11/28
3:05 pm-2:25 pm
1 stop14h 20m
$591
CataniaSan Francisco
CTA Catania Fontanarossa - SFO San Francisco
CTASFO
Catania Fontanarossa
Sat 12/12
6:00 am-1:10 pm
1 stop16h 10m
San Francisco
Sun 1/10
3:05 pm-11:30 pm
2 stops23h 25m
$618
CataniaSan Francisco
CTA Catania Fontanarossa - SFO San Francisco
CTASFO
Catania Fontanarossa
Thu 12/10
8:45 pm-11:45 am
1 stop24h 00m
San Francisco
Thu 12/17
7:00 am-8:55 am
1 stop16h 55m
$623
Showing 1-10 of 28 resultsSorted by cheapest first
Best time to book a flight from Sicily to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Sicily with our price prediction graph.
PMO-SFO
CTA-SFO
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Cheapflights Insights
Everything you need to know about your flight from Sicily to San Francisco
ITSI-SFO
PMO-SFO
CTA-SFO
What is the cheapest month to book a flight from Sicily to San Francisco?
Currently, November is the cheapest month in which you can book a flight from Sicily to San Francisco (average of $599). Flying from Sicily to San Francisco in May is currently the most expensive (average of $996). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Sicily to San Francisco?
Airfare is below average for this route at the moment.
Sicily to San Francisco flights typically cost between $661 and $930 in February.The cheapest round-trip price found within the last 5 days was $553 on Air Canada (Feb 5-Feb 14).
Related info for your journey
Find useful and relevant information for your journey from Sicily to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
San Bruno
Emeryville
Newark
Burlingame
Roseville
Redwood City
Rancho Cordova
Cupertino
Fairfield
San Ramon
Manteca
San Carlos
Vallejo
Turlock
Davis
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Alternative routes for Sicily to San Francisco
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Complete your trip
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Sicily and San Francisco flights
Browse other Sicily and San Francisco flight options. Last updated on October 26, 2026.
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Other flights to San Francisco
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 26, 2026.
Sicily to San Francisco flights
Consider these flights traveling from Sicily to San Francisco.
Top airline flying from Sicily to San Francisco
Discover the top airline that operate flights from Sicily to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 26, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$704 | Average$986 | FlexibilityNo cancel fee | On-time81% |