$396+ Cheap flights from Palermo (PMO) to San Francisco (SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/14. Fares are subject to change and may not be available on all flights or dates of travel.
PMO — SFO
Oct 26 — Nov 21
Round-trip
1 adult, Economy
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Find cheap flights from Palermo to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Palermo to San FranciscoExplore the most affordable flight options available from Palermo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
Explore the most affordable flight options available from Palermo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 26, 2026.
This lol.travel deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:45 am -
2 stops20h 48m
Tue 12/18:25 am -
2 stops39h 30m
Deal found 9/23![Multiple Airlines logo]()
$529
This lol.travel deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:05 pm -
1 stop27h 10m
Thu 10/294:05 pm -
1 stop18h 15m
Deal found 9/22![ITA Airways logo]()
$559
This Expedia deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/59:45 am -
1 stop15h 45m
Mon 11/97:00 am -
1 stop20h 20m
Deal found 9/24![Multiple Airlines logo]()
$577
This Expedia deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/199:45 am -
1 stop15h 45m
Tue 12/17:25 pm -
1 stop28h 30m
Deal found 9/21![SWISS logo]()
$578
This ResecentrumGruppen deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ResecentrumGruppen is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:10 am -
2 stops24h 39m
Tue 12/17:00 am -
2 stops19h 30m
Deal found 9/22![KLM logo]()
$583
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:45 am -
2 stops23h 14m
Sun 10/185:00 am -
2 stops17h 15m
Deal found 9/24![United Airlines logo]()
$587
Best flights from Palermo to San FranciscoDiscover carefully curated flight deals from Palermo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
Discover carefully curated flight deals from Palermo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 26, 2026.
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:45 am -
2 stops23h 14m
Sun 10/185:00 am -
2 stops17h 15m
Deal found 9/24![United Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:20 pm -
2 stops25h 28m
Mon 11/98:45 am -
2 stops18h 35m
Deal found 9/25![United Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/229:45 am -
1 stop20h 37m
Thu 10/299:20 pm -
2 stops55h 00m
Deal found 9/22![United Airlines logo]()
$591
Last-minute flights from Palermo to San FranciscoDiscover last-minute flight deals from Palermo to San Francisco. Data last updated September 26, 2026 and is based on user searches.
Discover last-minute flight deals from Palermo to San Francisco. Data last updated September 26, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:45 am -
1 stop15h 30m
Sun 9/277:35 pm -
1 stop33h 30m
Deal found 9/23![SWISS logo]()
$770
This Expedia deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/249:45 am -
1 stop15h 30m
Sun 9/279:05 pm -
2 stops26h 45m
Deal found 9/23![Multiple Airlines logo]()
$805
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/159:45 am -
1 stop18h 29m
Sun 10/186:00 am -
1 stop16h 15m
Deal found 9/24![United Airlines logo]()
$587
This oojo deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:30 pm -
1 stop25h 45m
Mon 6/213:15 pm -
1 stop15h 10m
Deal found 9/25![ITA Airways logo]()
$685
This Lufthansa deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:10 pm -
1 stop33h 50m
Sun 11/19:40 pm -
1 stop28h 20m
Deal found 9/22![Lufthansa logo]()
$802
This lol.travel deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:05 pm -
1 stop27h 10m
Thu 10/294:05 pm -
1 stop18h 15m
Deal found 9/22![ITA Airways logo]()
$559
This Mytrip deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:15 am -
2 stops19h 00m
Thu 10/293:45 pm -
3 stops20h 05m
Deal found 9/22![Multiple Airlines logo]()
$874
One-way flights from Palermo to San FranciscoSearch for one-way flight options from Palermo to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
Search for one-way flight options from Palermo to San Francisco. Find affordable one-way fares based on user searches. Data last updated September 26, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/148:45 pm -
2 stops51h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$396
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:05 pm -
2 stops34h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1511:35 am -
3 stops36h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$412
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:45 pm -
2 stops51h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$415
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1011:50 am -
2 stops35h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/711:35 am -
3 stops59h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:35 am -
3 stops46h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$455
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:15 am -
2 stops46h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$457
This Kiwi.com deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:05 pm -
2 stops34h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![Multiple Airlines logo]()
$459
Find flight deals from Palermo to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Palermo (PMO) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 26, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $529 (lol.travel) |
One-way from | $396 (Kiwi.com) |
Popular in | October |
Cheapest in | November |
Cheapflights Fare Finder
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 26, 2026.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Tue 11/3
6:15 am-8:10 pm
2 stops46h 55m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$457
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Mon 12/14
7:50 pm-3:35 pm
1 stop28h 45m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$550
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 10/15
9:45 am-11:59 pm
2 stops23h 14m
San Francisco
Sun 10/18
5:00 am-7:15 am
2 stops17h 15m
$587
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 11/5
2:20 pm-6:48 am
2 stops25h 28m
San Francisco
Mon 11/9
8:45 am-12:20 pm
2 stops18h 35m
$587
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 10/22
9:45 am-9:22 pm
1 stop20h 37m
San Francisco
Thu 10/29
9:20 pm-12:20 pm
2 stops55h 00m
$591
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Mon 11/2
9:35 am-5:30 pm
1 stop40h 55m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$644
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Sat 12/12
8:15 pm-8:10 pm
1 stop32h 55m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$680
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Wed 12/16
6:45 pm-4:30 pm
1 stop30h 45m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$686
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Fri 12/18
9:35 am-4:30 pm
1 stop39h 55m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$686
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Tue 10/20
3:40 pm-1:15 pm
1 stop30h 35m
San Francisco
Wed 12/31
12:00 am-9:00 am
Nonstop0h 00m
$706
Showing 1-10 of 13 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Palermo-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Palermo-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Palermo-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Palermo-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Palermo-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Palermo to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Palermo with our price prediction graph.
PMO-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Palermo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
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Santa Cruz
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Rancho Cordova
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Roseville
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Newark
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