$456+ Cheap flights from Palermo (PMO) to San Francisco (SFO)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
PMO — SFO
Sep 11 — Sep 181
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Palermo to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Palermo to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Palermo to San FranciscoExplore the most affordable flight options available from Palermo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
Explore the most affordable flight options available from Palermo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 12, 2026.
This lol.travel deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:15 am -
1 stop15h 00m
Sun 9/133:15 pm -
1 stop32h 50m
Deal found 8/10![ITA Airways logo]()
$577
This oojo deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:05 pm -
1 stop27h 10m
Sat 9/193:15 pm -
1 stop15h 05m
Deal found 8/8![ITA Airways logo]()
$601
This Gotogate deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:55 pm -
1 stop34h 20m
Mon 9/77:35 pm -
1 stop28h 25m
Deal found 8/9![SWISS logo]()
$606
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:05 pm -
1 stop25h 10m
Mon 9/73:15 pm -
1 stop20h 50m
Deal found 8/10![ITA Airways logo]()
$610
This Scandinavian Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:50 pm -
1 stop28h 50m
Fri 9/116:23 am -
2 stops25h 47m
Deal found 8/8![Scandinavian Airlines logo]()
$621
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:25 am -
2 stops21h 51m
Mon 9/77:35 pm -
1 stop28h 25m
Deal found 8/10![Multiple Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:45 am -
1 stop18h 29m
Thu 9/37:49 pm -
2 stops26h 26m
Deal found 8/9![United Airlines logo]()
$641
This lol.travel deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:05 pm -
1 stop25h 10m
Fri 9/113:15 pm -
1 stop20h 50m
Deal found 8/8![ITA Airways logo]()
$643
Best flights from Palermo to San FranciscoDiscover carefully curated flight deals from Palermo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
Discover carefully curated flight deals from Palermo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 12, 2026.
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:45 am -
1 stop18h 29m
Thu 9/37:49 pm -
2 stops26h 26m
Deal found 8/9![United Airlines logo]()
$641
This Expedia deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/38:10 pm -
2 stops25h 30m
Mon 9/77:35 pm -
1 stop28h 25m
Deal found 8/7![Multiple Airlines logo]()
$652
This Gotogate deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:10 am -
1 stop16h 05m
Mon 9/73:15 pm -
2 stops23h 05m
Deal found 8/8![ITA Airways logo]()
$655
This ITA Airways deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/246:10 am -
1 stop16h 05m
Sun 9/63:15 pm -
1 stop18h 05m
Deal found 8/9![ITA Airways logo]()
$685
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:45 am -
1 stop18h 29m
Mon 9/711:59 pm -
2 stops46h 16m
Deal found 8/8![United Airlines logo]()
$714
This ITA Airways deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:10 am -
1 stop16h 05m
Fri 9/113:15 pm -
1 stop19h 30m
Deal found 8/8![ITA Airways logo]()
$694
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:10 am -
1 stop22h 15m
Sun 10/2511:15 pm -
2 stops29h 05m
Deal found 8/10![United Airlines logo]()
$801
This ITA Airways deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure ITA Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:10 am -
1 stop16h 05m
Sun 10/256:15 am -
2 stops24h 05m
Deal found 8/11![ITA Airways logo]()
$811
Last-minute flights from Palermo to San FranciscoDiscover last-minute flight deals from Palermo to San Francisco. Data last updated August 12, 2026 and is based on user searches.
Discover last-minute flight deals from Palermo to San Francisco. Data last updated August 12, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/279:45 am -
1 stop18h 29m
Thu 9/37:49 pm -
2 stops26h 26m
Deal found 8/9![United Airlines logo]()
$641
This Scandinavian Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Scandinavian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:50 pm -
1 stop28h 50m
Fri 9/116:23 am -
2 stops25h 47m
Deal found 8/8![Scandinavian Airlines logo]()
$621
This Gotogate deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:55 pm -
1 stop34h 20m
Mon 9/77:35 pm -
1 stop28h 25m
Deal found 8/9![SWISS logo]()
$606
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:05 pm -
1 stop25h 10m
Mon 9/73:15 pm -
1 stop20h 50m
Deal found 8/10![ITA Airways logo]()
$610
This Expedia deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/311:25 am -
2 stops21h 51m
Mon 9/77:35 pm -
1 stop28h 25m
Deal found 8/10![Multiple Airlines logo]()
$631
This lol.travel deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:05 pm -
1 stop25h 10m
Fri 9/113:15 pm -
1 stop20h 50m
Deal found 8/8![ITA Airways logo]()
$643
This oojo deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/47:05 pm -
1 stop27h 10m
Sat 9/193:15 pm -
1 stop15h 05m
Deal found 8/8![ITA Airways logo]()
$601
This lol.travel deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lol.travel is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:15 am -
1 stop15h 00m
Sun 9/133:15 pm -
1 stop32h 50m
Deal found 8/10![ITA Airways logo]()
$577
One-way flights from Palermo to San FranciscoSearch for one-way flight options from Palermo to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
Search for one-way flight options from Palermo to San Francisco. Find affordable one-way fares based on user searches. Data last updated August 12, 2026.
This Iberia deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/131:25 pm -
2 stops30h 07m
Deal found 8/11![Multiple Airlines logo]()
$456
This Orbitz deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/299:50 pm -
2 stops50h 05m
Deal found 8/8![Iberia logo]()
$466
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:20 pm -
2 stops48h 10m
Deal found 8/8![Multiple Airlines logo]()
$473
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/711:15 pm -
2 stops24h 15m
Deal found 8/8![Multiple Airlines logo]()
$480
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:15 pm -
2 stops24h 15m
Deal found 8/8![Multiple Airlines logo]()
$488
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/287:40 pm -
3 stops48h 30m
Deal found 8/8![Multiple Airlines logo]()
$498
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:15 am -
3 stops44h 20m
Deal found 8/7![Multiple Airlines logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/312:35 pm -
2 stops40h 35m
Deal found 8/8![Multiple Airlines logo]()
$516
Find flight deals from Palermo to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Palermo (PMO) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $577 (lol.travel) |
One-way from | $456 (Iberia) |
Cheapflights Fare Finder
Customize your flight search to find flights from Palermo to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 12, 2026.
Use the filters below to find and compare flights from Palermo to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 8/27
9:45 am-7:14 pm
1 stop18h 29m
San Francisco
Thu 9/3
7:49 pm-7:15 am
2 stops26h 26m
$641
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 9/3
8:10 pm-12:40 pm
2 stops25h 30m
San Francisco
Mon 9/7
7:35 pm-9:00 am
1 stop28h 25m
$652
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 9/3
6:10 am-1:15 pm
1 stop16h 05m
San Francisco
Mon 9/7
3:15 pm-11:20 pm
2 stops23h 05m
$655
Quickest round-trip
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Mon 8/24
6:10 am-1:15 pm
1 stop16h 05m
San Francisco
Sun 9/6
3:15 pm-6:20 pm
1 stop18h 05m
$685
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Tue 9/1
6:10 am-1:15 pm
1 stop16h 05m
San Francisco
Fri 9/11
3:15 pm-7:45 pm
1 stop19h 30m
$694
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Thu 9/3
9:45 am-7:14 pm
1 stop18h 29m
San Francisco
Mon 9/7
11:59 pm-7:15 am
2 stops46h 16m
$714
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Wed 10/21
6:10 am-7:25 pm
1 stop22h 15m
San Francisco
Sun 10/25
11:15 pm-12:20 pm
2 stops29h 05m
$801
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Wed 10/21
6:10 am-1:15 pm
1 stop16h 05m
San Francisco
Sun 10/25
6:15 am-2:20 pm
2 stops24h 05m
$811
Cheapest one-way
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Tue 10/13
1:25 pm-10:32 am
2 stops30h 07m
$456
PalermoSan Francisco
PMO Palermo Punta Raisi - SFO San Francisco
PMOSFO
Palermo Punta Raisi
Sat 11/28
7:40 pm-11:10 am
3 stops48h 30m
$498
Showing 1-10 of 18 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Palermo-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Palermo-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Palermo-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Palermo-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Palermo-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Palermo to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Palermo with our price prediction graph.
PMO-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Palermo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
San Bruno
Fairfield
Emeryville
Roseville
Burlingame
Rancho Cordova
Vallejo
Cupertino
Newark
Hayward
San Ramon
Redwood City
San Carlos
Manteca
Turlock
San Lorenzo
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
San Francisco flight routes