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$564+ Cheap flights from Santander (SDR) to San Francisco (SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/4. Fares are subject to change and may not be available on all flights or dates of travel.
SDR — SFO
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
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Cheap flight deals from Santander to San Francisco

Cheapest flights from Santander to San Francisco
Explore the most affordable flight options available from Santander to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Expedia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:00 am
SDR
-
SFO
2 stops22h 16m
Iberia
Wed 3/1810:03 am
SFO
-
SDR
2 stops23h 07m
Iberia
Deal found 1/25$640
This Iberia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/39:00 am
SDR
-
SFO
2 stops22h 40m
Iberia
Tue 3/1710:36 am
SFO
-
SDR
2 stops22h 34m
Iberia
Deal found 1/27$641
This Iberia deal was found by Cheapflights users on 1/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/39:40 am
SDR
-
SFO
1 stop17h 25m
Iberia
Mon 9/74:35 pm
SFO
-
SDR
2 stops39h 25m
Iberia
Deal found 1/24$704
This Iberia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:10 am
SDR
-
SFO
1 stop16h 50m
Iberia
Tue 7/144:35 pm
SFO
-
SDR
2 stops31h 25m
Iberia
Deal found 1/25$754
This Iberia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/154:35 pm
SDR
-
SFO
1 stop34h 25m
Iberia
Tue 7/144:35 pm
SFO
-
SDR
2 stops31h 25m
Iberia
Deal found 1/25$763
This Iberia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/1610:10 am
SDR
-
SFO
1 stop16h 50m
Iberia
Mon 7/136:00 am
SFO
-
SDR
2 stops30h 00m
Iberia
Deal found 1/25$770
This Iberia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/145:40 pm
SDR
-
SFO
2 stops53h 10m
Iberia
Tue 7/144:35 pm
SFO
-
SDR
2 stops31h 25m
Iberia
Deal found 1/25$772
This Iberia deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/139:20 am
SDR
-
SFO
1 stop15h 50m
Iberia
Tue 7/144:35 pm
SFO
-
SDR
2 stops31h 25m
Iberia
Deal found 1/25$774

Find flight deals from Santander to San Francisco

Discover tips and strategies to find the most affordable flight options for your journey from Santander (SDR) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

Expedia
1 star

Most trusted provider

Expedia
3 stars

Round-trip from

$640
(Expedia)

One-way from

$564
(Cheapflightsfares)
Provider with most accurate pricing for Santander-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santander-San Francisco flights.
Search Deals
From Santander to San Francisco
Search Deals
One-way flight from Santander to San Francisco
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santander to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Santander to San Francisco that are best for you.

Fly from

Santander

Fly to

San Francisco

Route

Depart

Return

Price

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Wed 3/11

9:00 am-11:16 pm

2 stops22h 16m

San Francisco

Wed 3/18

10:03 am-5:10 pm

2 stops23h 07m

$640

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Tue 3/3

9:00 am-10:40 pm

2 stops22h 40m

San Francisco

Tue 3/17

10:36 am-5:10 pm

2 stops22h 34m

$641

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Tue 6/16

10:10 am-6:00 pm

1 stop16h 50m

San Francisco

Mon 7/13

6:00 am-9:00 pm

2 stops30h 00m

$770

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Sun 6/14

5:40 pm-1:50 pm

2 stops53h 10m

San Francisco

Tue 7/14

4:35 pm-9:00 am

2 stops31h 25m

$772

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Tue 6/16

10:10 am-6:00 pm

1 stop16h 50m

San Francisco

Tue 7/14

7:50 pm-9:00 am

1 stop28h 10m

$773

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Mon 6/15

4:35 pm-6:00 pm

1 stop34h 25m

San Francisco

Mon 7/13

6:00 am-9:00 pm

2 stops30h 00m

$779

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Wed 6/17

10:05 am-1:50 pm

2 stops36h 45m

San Francisco

Mon 7/13

6:00 am-9:00 pm

2 stops30h 00m

$780

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Fri 6/12

9:35 pm-4:10 pm

1 stop27h 35m

San Francisco

Tue 7/14

4:35 pm-9:00 am

2 stops31h 25m

$784

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Mon 6/15

10:05 am-1:50 pm

2 stops36h 45m

San Francisco

Sun 7/12

6:00 am-5:00 pm

2 stops26h 00m

$797

SantanderSan Francisco

SDR - SFO

SDRSFO

Santander

Thu 6/4

10:05 am-4:10 pm

1 stop15h 05m

$564

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 11 results
1
2
  • Most accurate provider: When it comes to deals on Santander-San Francisco flights, users find the pricing of Expedia to be most consistent on Cheapflights vs. Expedia Users can find the same prices on Santander-San Francisco flight deals on Cheapflights vs. Expedia <90% of the time. Price accuracy is based on data collected from Santander-San Francisco flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santander-San Francisco flights, Cheapflights users trust Expedia the most. Expedia has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santander-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santander to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Santander with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santander to San Francisco

What is the cheapest month to book a flight from Santander to San Francisco?

Currently, September is the cheapest month in which you can book a flight from Santander to San Francisco (average of $332). Flying from Santander to San Francisco in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santander to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santander to San Francisco?

    Airlines like Iberia fly from Santander to San Francisco in about 22h 16m. The time it takes to get you to your destination can typically vary by up to . The distance between Santander and San Francisco is about 5640 mi.

  • Can I find deals for flights from Santander to San Francisco that include hotel bookings?

    Yes. In addition to deals on Santander to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santander to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santander to San Francisco.

  • Can I find deals for business class flights from Santander to San Francisco?

    Yes. Cheapflights offers flight deals from Santander to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santander to San Francisco?

    Currently, September is the cheapest month in which you can book a flight from Santander to San Francisco (average of $332). Flying from Santander to San Francisco in July is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Roseville
Santa Clara
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
Manteca
Vallejo
San Lorenzo
Davis
Hollister
Redwood City
Union City

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