How long is the flight from Panama City, Florida to San Francisco?

Delta and United Airlines can get you from Panama City, Florida to San Francisco in just under 8h 55m. Your travel time can differ by up to 04m. Panama City, Florida and San Francisco are separated by a distance of 2139 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Panama City, Florida to San Francisco round-trip?

Currently priced at $297, Delta will fly you from Panama City, Florida to San Francisco and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $306 and $360, respectively. Delta is priced at 34% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from Panama City, Florida to San Francisco one-way?

$153 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $168 and $199, respectively.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 4.4 inches per month. January is typically the wettest month, when rainfall can reach 4.4 in. July is typically the driest time to visit San Francisco when rainfall is around 0.0 in.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

What are the most popular airlines that fly from Panama City, Florida to San Francisco?

Consider Delta, United Airlines or American Airlines when booking your flight. These represent the most popular airlines when flying from Panama City, Florida to San Francisco.

Most accurate provider : When it comes to deals on Panama City, Florida-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Francisco flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Panama City, Florida-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Panama City to San Francisco that include hotel bookings?

Yes. In addition to deals on Panama City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Francisco.

Can I find deals for business class flights from Panama City to San Francisco?

Yes. Cheapflights offers flight deals from Panama City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$151+ Flights from Panama City, FL to San Francisco

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Cheap flight deals from Panama City to San Francisco

Cheapest flights from Panama City to San Francisco
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Fri 12/264:45 pmECP - SFO

1 stop9h 36mUnited Airlines

Wed 12/3112:30 amSFO - ECP

1 stop6h 47mUnited Airlines

Deal found 12/25

$744

Fri 12/267:15 amECP - SFO

2 stops10h 43mAmerican Airlines

Thu 1/11:31 pmSFO - ECP

1 stop8h 22mAmerican Airlines

Deal found 12/25

$798

Fri 12/269:50 amECP - SFO

2 stops10h 25mSouthwest

Thu 1/15:50 amSFO - ECP

2 stops11h 15mSouthwest

Deal found 12/25

$933

Best flights from Panama City to San Francisco
Discover carefully curated flight deals from Panama City to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 27, 2025.

Sun 1/186:00 amECP - SFO

1 stop8h 55mDelta

Tue 1/272:05 pmSFO - ECP

1 stop6h 35mDelta

Deal found 12/26

$330

Tue 3/35:00 pmECP - SFO

1 stop8h 59mUnited Airlines

Tue 3/107:20 amSFO - ECP

1 stop6h 51mUnited Airlines

Deal found 12/25

$359

Thu 1/157:02 amECP - SFO

2 stops10h 03mAmerican Airlines

Mon 1/197:00 amSFO - ECP

1 stop8h 33mAmerican Airlines

Deal found 12/25

$390

Wed 4/153:00 pmECP - SFO

1 stop9h 10mSouthwest

Wed 4/226:20 amSFO - ECP

1 stop9h 25mSouthwest

Deal found 12/26

$437

Thu 1/156:30 amECP - SFO

1 stop7h 50mUnited Airlines

Mon 1/195:00 amSFO - ECP

1 stop9h 12mUnited Airlines

Deal found 12/25

$385

Thu 1/223:27 pmECP - SFO

2 stops9h 13mAmerican Airlines

Thu 1/297:00 amSFO - ECP

1 stop8h 33mAmerican Airlines

Deal found 12/25

$390

Thu 1/221:10 pmECP - SFO

1 stop7h 50mUnited Airlines

Thu 1/295:00 amSFO - ECP

1 stop9h 12mUnited Airlines

Deal found 12/25

$385

Sat 1/176:30 amECP - SFO

1 stop10h 26mUnited Airlines

Mon 1/1912:43 amSFO - ECP

1 stop9h 19mUnited Airlines

Deal found 12/24

$401

Tue 3/314:57 pmECP - SFO

1 stop7h 47mUnited Airlines

Mon 4/612:45 amSFO - ECP

1 stop6h 50mUnited Airlines

Deal found 12/26

$437

Last-minute flights from Panama City to San Francisco
Discover last-minute flight deals from Panama City to San Francisco. Data last updated December 27, 2025 and is based on user searches.

Fri 1/96:30 amECP - SFO

1 stop10h 26mUnited Airlines

Tue 1/137:18 amSFO - ECP

1 stop6h 54mUnited Airlines

Deal found 12/25

$557

Thu 1/156:30 amECP - SFO

1 stop7h 50mUnited Airlines

Mon 1/195:00 amSFO - ECP

1 stop9h 12mUnited Airlines

Deal found 12/25

$385

Thu 1/157:02 amECP - SFO

2 stops10h 03mAmerican Airlines

Mon 1/197:00 amSFO - ECP

1 stop8h 33mAmerican Airlines

Deal found 12/25

$390

Sat 1/176:30 amECP - SFO

1 stop7h 50mUnited Airlines

Mon 1/1912:43 amSFO - ECP

1 stop9h 19mUnited Airlines

Deal found 12/25

$401

Sun 1/186:00 amECP - SFO

1 stop8h 55mDelta

Tue 1/272:05 pmSFO - ECP

1 stop6h 35mDelta

Deal found 12/26

$330

Thu 1/2212:03 pmECP - SFO

2 stops12h 37mAmerican Airlines

Thu 1/297:00 amSFO - ECP

2 stops12h 19mAmerican Airlines

Deal found 12/25

$395

One-way flights from Panama City to San Francisco
Search for one-way flight options from Panama City to San Francisco. Find affordable one-way fares based on user searches. Data last updated December 27, 2025.

Wed 2/183:32 pmECP - SFO

1 stop8h 32mAmerican Airlines

Deal found 12/25

$151

Thu 1/2212:03 pmECP - SFO

1 stop10h 22mAmerican Airlines

Deal found 12/25

$193

Fri 2/204:30 pmECP - SFO

1 stop8h 44mAmerican Airlines

Deal found 12/25

$219

Thu 1/226:30 amECP - SFO

3 stops18h 28mUnited Airlines

Deal found 12/25

$451

Fri 1/29:50 amECP - SFO

2 stops8h 25mSouthwest

Deal found 12/26

$549

Fri 2/206:00 amECP - SFO

3 stops18h 56mMultiple Airlines

Deal found 12/25

$609

Fri 1/26:15 amECP - SFO

1 stop7h 59mUnited Airlines

Deal found 12/26

$679

Find flight deals from Panama City to San Francisco

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$330 (Delta)
One-way from	$151 (American Airlines)
Popular in	May
Cheapest in	April
Average price	$471

Provider with most accurate pricing for Panama City NW Florida Beaches-San Francisco flight deals.

Search Deals

Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-San Francisco flights.

Search Deals

From Panama City NW Florida Beaches to San Francisco

Search Deals

One-way flight from Panama City NW Florida Beaches to San Francisco

Search Deals

High demand for flights, 2% potential price rise

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Sun 1/18

6:00 am-12:55 pm

1 stop8h 55m

San Francisco

Tue 1/27

2:05 pm-10:40 pm

1 stop6h 35m

$330

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/3

5:00 pm-11:59 pm

1 stop8h 59m

San Francisco

Tue 3/10

7:20 am-4:11 pm

1 stop6h 51m

$359

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Thu 1/15

6:30 am-12:20 pm

1 stop7h 50m

San Francisco

Mon 1/19

5:00 am-4:12 pm

1 stop9h 12m

$385

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Thu 1/22

1:10 pm-7:00 pm

1 stop7h 50m

San Francisco

Thu 1/29

5:00 am-4:12 pm

1 stop9h 12m

$385

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Thu 1/15

7:02 am-3:05 pm

2 stops10h 03m

San Francisco

Mon 1/19

7:00 am-5:33 pm

1 stop8h 33m

$390

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Thu 1/22

3:27 pm-10:40 pm

2 stops9h 13m

San Francisco

Thu 1/29

7:00 am-5:33 pm

1 stop8h 33m

$390

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Sat 1/17

6:30 am-2:56 pm

1 stop10h 26m

San Francisco

Mon 1/19

12:43 am-12:02 pm

1 stop9h 19m

$401

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Wed 4/15

3:00 pm-10:10 pm

1 stop9h 10m

San Francisco

Wed 4/22

6:20 am-5:45 pm

1 stop9h 25m

$437

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Tue 3/31

4:57 pm-10:44 pm

1 stop7h 47m

San Francisco

Mon 4/6

12:45 am-9:35 am

1 stop6h 50m

$437

Panama CitySan Francisco

ECP - SFO

ECPSFO

Panama City NW Florida Beaches

Wed 2/18

12:37 pm-8:42 pm

2 stops10h 05m

$156

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Showing 1-10 of 16 results

Compare providers for flights from Panama City to San Francisco

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in December.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*1 star
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Panama City, Florida-San Francisco flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Panama City, Florida-San Francisco flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Panama City, Florida-San Francisco flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Panama City, Florida-San Francisco flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Panama City, Florida-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Panama City to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Francisco

What is the cheapest month to book a flight from Panama City, Florida to San Francisco?

Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to San Francisco (average of $106). Flying from Panama City, Florida to San Francisco in July is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to SFO?

Unlike at noon, when flights are generally more expensive, you can save up to 22% on flights from Panama City, Florida to San Francisco by exploring options for tickets in the evening.

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Panama City to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,258 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

8,018 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

9,116 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

11,068 reviews

Southwest

8.0

Very good

4,258 reviews

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

How long is the flight from Panama City, Florida to San Francisco?
Delta and United Airlines can get you from Panama City, Florida to San Francisco in just under 8h 55m. Your travel time can differ by up to 04m. Panama City, Florida and San Francisco are separated by a distance of 2139 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Panama City, Florida to San Francisco round-trip?
Currently priced at $297, Delta will fly you from Panama City, Florida to San Francisco and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from United Airlines and American Airlines - these airlines can fly you to your destination from $306 and $360, respectively. Delta is priced at 34% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from Panama City, Florida to San Francisco one-way?
$153 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and United Airlines, with prices starting from $168 and $199, respectively.
Can I find deals for flights from Panama City to San Francisco that include hotel bookings?
Yes. In addition to deals on Panama City to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to San Francisco.
Can I find deals for business class flights from Panama City to San Francisco?
Yes. Cheapflights offers flight deals from Panama City to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City, Florida to San Francisco?
Currently, December is the cheapest month in which you can book a flight from Panama City, Florida to San Francisco (average of $106). Flying from Panama City, Florida to San Francisco in July is currently the most expensive (average of $342). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Roseville

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Santa Cruz

Livermore

Turlock

Manteca

Watsonville

Redwood City

Sunnyvale

San Bruno

Daly City

Santa Clara

San Carlos

Vallejo

Hollister

San Ramon

Foster City

Union City

Davis

Emeryville

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Panama City to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$297	Average$397	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$306	Average$471	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$360	Average$469	FlexibilityNo cancel fee	On-time71%
Southwest	Cheapest$389	Average$492	FlexibilityNo cancel fee	On-time63%

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$151+ Cheap flights from Panama City, FL to San Francisco (ECP - SFO)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Panama City to San Francisco with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheap flight deals from Panama City to San Francisco

Cheapest flights from Panama City to San FranciscoExplore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.

Find flight deals from Panama City to San Francisco

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to San Francisco that are best for you.

Compare providers for flights from Panama City to San Francisco

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Panama City to San Francisco in December.

Best time to book a flight from Panama City to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Panama City with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Panama City to San Francisco

What is the cheapest month to book a flight from Panama City, Florida to San Francisco?

What is the cheapest time of day to fly from ECP to SFO?

Reviews of airlines servicing San Francisco

Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Panama City to San Francisco. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Panama City to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Panama City, Florida to San Francisco?

What are the cheapest airlines flying from Panama City, Florida to San Francisco round-trip?

What are the cheapest airlines to fly from Panama City, Florida to San Francisco one-way?

Can I find deals for flights from Panama City to San Francisco that include hotel bookings?

How can I find direct flights from Panama City to San Francisco?

Can I find deals for business class flights from Panama City to San Francisco?

What is the cheapest month to book a flight from Panama City, Florida to San Francisco?

Traveling to a place near San Francisco?

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Alternative routes for Panama City to San Francisco

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Top 4 airlines flying from Panama City to San Francisco

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Cheapest flights from Panama City to San Francisco
Explore the most affordable flight options available from Panama City to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 27, 2025.