$139+ Cheap flights from Indianapolis to San Francisco (IND - SFO)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/12. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SFO
Dec 4 — Dec 111
Round-trip
1 adult, Economy
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Find cheap flights from Indianapolis to San Francisco with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Indianapolis to San Francisco are usually found in September or May, booked 15 days in advance, depart on a Thursday or Friday and return on a Saturday
Cheap flight deals from Indianapolis to San Francisco
Cheapest
Best
Last-minute
One-way
Cheapest flights from Indianapolis to San FranciscoExplore the most affordable flight options available from Indianapolis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
Explore the most affordable flight options available from Indianapolis to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 4, 2026.
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:28 am -
1 stop7h 05m
Tue 1/56:47 am -
1 stop9h 39m
Deal found 11/3![American Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:30 pm -
1 stop6h 58m
Wed 12/306:15 am -
1 stop6h 20m
Deal found 11/3![Frontier logo]()
$375
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:03 pm -
1 stop11h 17m
Thu 11/126:02 am -
1 stop6h 06m
Deal found 11/3![Frontier logo]()
$376
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:00 am -
1 stop8h 49m
Sat 1/95:00 am -
1 stop10h 01m
Deal found 11/1![American Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:46 pm -
1 stop10h 04m
Tue 11/175:07 pm -
2 stops19h 01m
Deal found 10/30![Frontier logo]()
$378
This CheapOair deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:41 pm -
1 stop9h 12m
Tue 1/52:07 pm -
2 stops46h 12m
Deal found 10/31![Frontier logo]()
$379
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:37 pm -
1 stop6h 51m
Wed 11/256:15 am -
1 stop6h 27m
Deal found 11/2![Frontier logo]()
$380
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am -
1 stop13h 03m
Sat 1/91:25 pm -
1 stop6h 34m
Deal found 10/31![Delta logo]()
$381
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/201:33 pm -
1 stop12h 32m
Mon 12/2810:21 pm -
2 stops14h 14m
Deal found 11/2![Frontier logo]()
$382
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:58 pm -
2 stops22h 03m
Mon 11/239:11 pm -
2 stops21h 24m
Deal found 10/30![Frontier logo]()
$383
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:00 am -
1 stop8h 19m
Wed 12/211:00 am -
Nonstop4h 19m
Deal found 11/1![United Airlines logo]()
$384
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:00 am -
1 stop30h 44m
Wed 12/3010:21 pm -
2 stops17h 37m
Deal found 11/2![Multiple Airlines logo]()
$385
Best flights from Indianapolis to San FranciscoDiscover carefully curated flight deals from Indianapolis to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
Discover carefully curated flight deals from Indianapolis to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 4, 2026.
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/83:41 pm -
1 stop8h 33m
Wed 1/1310:47 am -
Nonstop4h 20m
Deal found 11/1![United Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/217:00 pm -
1 stop8h 06m
Sun 12/276:30 am -
1 stop7h 15m
Deal found 11/2![Delta logo]()
$419
This Alaska Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:30 am -
2 stops15h 50m
Mon 11/168:58 pm -
2 stops13h 18m
Deal found 10/30![Alaska Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/47:00 am -
Nonstop5h 01m
Mon 12/711:00 am -
Nonstop4h 19m
Deal found 11/3![United Airlines logo]()
$399
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:40 pm -
1 stop8h 45m
Tue 1/510:21 am -
2 stops9h 38m
Deal found 11/3![Delta logo]()
$421
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:14 am -
Nonstop5h 01m
Mon 11/235:00 am -
1 stop8h 23m
Deal found 10/30![United Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
1 stop8h 19m
Mon 11/3010:53 pm -
Nonstop4h 19m
Deal found 11/3![United Airlines logo]()
$440
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:35 am -
1 stop8h 47m
Fri 12/46:00 am -
2 stops10h 02m
Deal found 10/31![Delta logo]()
$501
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/222:02 pm -
1 stop7h 55m
Mon 12/2810:45 pm -
Nonstop4h 22m
Deal found 11/2![United Airlines logo]()
$508
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/237:13 am -
Nonstop5h 17m
Tue 12/2910:45 pm -
Nonstop4h 22m
Deal found 10/31![United Airlines logo]()
$516
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/117:00 am -
Nonstop5h 01m
Mon 12/1411:00 am -
Nonstop4h 19m
Deal found 11/1![United Airlines logo]()
$519
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:29 pm -
Nonstop5h 01m
Mon 11/3010:53 pm -
Nonstop4h 19m
Deal found 11/3![United Airlines logo]()
$519
Last-minute flights from Indianapolis to San FranciscoDiscover last-minute flight deals from Indianapolis to San Francisco. Data last updated November 4, 2026 and is based on user searches.
Discover last-minute flight deals from Indianapolis to San Francisco. Data last updated November 4, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:03 pm -
1 stop11h 17m
Thu 11/126:02 am -
1 stop6h 06m
Deal found 11/3![Frontier logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/141:46 pm -
1 stop10h 04m
Tue 11/175:07 pm -
2 stops19h 01m
Deal found 10/30![Frontier logo]()
$378
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:58 pm -
2 stops22h 03m
Mon 11/239:11 pm -
2 stops21h 24m
Deal found 10/30![Frontier logo]()
$383
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:37 pm -
1 stop6h 51m
Wed 11/256:15 am -
1 stop6h 27m
Deal found 11/2![Frontier logo]()
$380
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/267:00 am -
1 stop8h 19m
Wed 12/211:00 am -
Nonstop4h 19m
Deal found 11/1![United Airlines logo]()
$384
This CheapOair deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:41 pm -
1 stop9h 12m
Tue 1/52:07 pm -
2 stops46h 12m
Deal found 11/1![Frontier logo]()
$379
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/167:00 am -
1 stop13h 03m
Sat 1/91:25 pm -
1 stop6h 34m
Deal found 10/31![Delta logo]()
$381
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/187:00 am -
1 stop8h 49m
Sat 1/95:00 am -
1 stop10h 01m
Deal found 11/1![American Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/201:33 pm -
1 stop12h 32m
Mon 12/2810:21 pm -
2 stops14h 14m
Deal found 11/2![Frontier logo]()
$382
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/214:30 pm -
1 stop6h 58m
Wed 12/306:15 am -
1 stop6h 20m
Deal found 11/3![Frontier logo]()
$375
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/225:28 am -
1 stop7h 05m
Tue 1/56:47 am -
1 stop9h 39m
Deal found 11/3![American Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/258:00 am -
1 stop30h 44m
Wed 12/3010:21 pm -
2 stops17h 37m
Deal found 11/2![Multiple Airlines logo]()
$385
One-way flights from Indianapolis to San FranciscoSearch for one-way flight options from Indianapolis to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
Search for one-way flight options from Indianapolis to San Francisco. Find affordable one-way fares based on user searches. Data last updated November 4, 2026.
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/124:41 pm -
1 stop9h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$139
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:12 pm -
2 stops27h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$140
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/14:41 pm -
1 stop28h 48m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$144
This Cheapflightsfares deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/184:30 pm -
1 stop6h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$149
This Frontier deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/67:12 pm -
1 stop8h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:00 am -
1 stop27h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/24:04 pm -
2 stops35h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Frontier logo]()
$152
This Mytrip deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2110:56 am -
2 stops16h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/30![Frontier logo]()
$153
This Super.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/71:46 pm -
1 stop10h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/54:41 pm -
2 stops30h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Frontier logo]()
$155
Find flight deals from Indianapolis to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Indianapolis (IND) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $374 (American Airlines) |
One-way from | $139 (Cheapflightsfares) |
Popular in | November |
Cheapest in | September |
Average price | $475 |
Good round-trip deal | $513 or less |
Good one-way deal | $248 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Indianapolis to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
Use the filters below to find and compare flights from Indianapolis to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Mon 11/23
11:10 am-7:05 pm
2 stops10h 55m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$215
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Sat 11/21
10:30 pm-11:01 am
2 stops39h 31m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$223
Quickest round-trip
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Thu 12/10
7:30 pm-9:31 pm
Nonstop5h 01m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$234
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Fri 12/18
3:25 pm-11:55 pm
2 stops11h 30m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$239
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Thu 11/19
2:40 pm-8:10 pm
2 stops8h 30m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$250
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Wed 12/30
6:20 am-1:40 pm
1 stop10h 20m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$274
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Fri 12/25
7:20 am-7:55 pm
2 stops15h 35m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$293
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Sun 1/3
7:23 am-10:57 pm
2 stops18h 34m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$294
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Fri 12/18
7:13 am-9:30 am
Nonstop5h 17m
San Francisco
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$379
IndianapolisSan Francisco
IND Indianapolis - SFO San Francisco
INDSFO
Indianapolis
Fri 1/8
3:41 pm-9:14 pm
1 stop8h 33m
San Francisco
Wed 1/13
10:47 am-6:07 pm
Nonstop4h 20m
$388
Showing 1-10 of 23 resultsSorted by cheapest first
Compare providers for flights from Indianapolis to San Francisco
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Indianapolis to San Francisco in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*1 star |
- Most accurate provider: When it comes to deals on Indianapolis-San Francisco flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Indianapolis-San Francisco flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Indianapolis-San Francisco flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Indianapolis-San Francisco flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Indianapolis-San Francisco flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Indianapolis to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Indianapolis with our price prediction graph.
IND-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Indianapolis to San Francisco
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How far ahead should I book a flight from Indianapolis to San Francisco?
The best time to book flights from Indianapolis to San Francisco is 14 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Indianapolis to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Indianapolis to San Francisco (average of $381). Flying from Indianapolis to San Francisco in November is currently the most expensive (average of $475). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IND to SFO?
Find hourly flight availability from Indianapolis to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 4, 2026.
When flying from Indianapolis to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
What’s the top layover airport for flights from Indianapolis to San Francisco?
Share of 1-stop round-trip flights from Indianapolis to San Francisco chosen by Cheapflights users in the past 12 months, using the same layover each way.
Denver (DEN) – chosen by Cheapflights users on 57% of 1-stop itineraries from Indianapolis to San Francisco on Cheapflights.
What’s the cheapest layover airport for flights from Indianapolis to San Francisco?
Average round-trip fare for 1-stop flights from Indianapolis to San Francisco, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Las Vegas (LAS) is the most affordable 1-stop option, with an average round-trip price of $252.
What’s the fastest layover option from Indianapolis to San Francisco?
Shortest average travel time for 1-stop one-way flights from Indianapolis to San Francisco, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Las Vegas (LAS) have the shortest average one-way travel time for 1-stop routes: 7h 05m.
Which airport typically offers the quickest layover for flights from Indianapolis to San Francisco?
Average layover duration for 1-stop one-way flights from Indianapolis to San Francisco, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Los Angeles (LAX) offer the fastest connection on this route, with an average layover time of 1h 07m.
The best insider tips for Indianapolis to San Francisco flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Indianapolis to San Francisco trip
Our travel experts
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated November 4, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Indianapolis to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Indianapolis to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Francisco?
Book flights to San Francisco if you plan to visit one of these locationsSouth San Francisco
Santa Clara
Santa Cruz
Walnut Creek
Hayward
Emeryville
Newark
Burlingame
San Bruno
Rancho Cordova
Vallejo
Cupertino
Fairfield
Redwood City
San Carlos
Sunnyvale
Turlock
Davis
Morgan Hill
Roseville
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Indianapolis and San Francisco flights
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Top 6 airlines flying from Indianapolis to San Francisco
Discover the top 6 airlines that operate flights from Indianapolis to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$150 | Average$301 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$228 | Average$423 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$430 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$278 | Average$441 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$288 | Average$385 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$288 | Average$446 | FlexibilityNo cancel fee | On-time63% |