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$309+ Cheap flights from Biloxi, MS to San Francisco (SFO)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/19. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SFO
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from Biloxi to San Francisco

Cheapest flights from Biloxi to San Francisco
Explore the most affordable flight options available from Biloxi to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/197:35 pm
GPT
-
SFO
1 stop7h 13m
American Airlines
Mon 2/2311:35 pm
SFO
-
GPT
1 stop8h 38m
American Airlines
Deal found 1/26$309
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:34 pm
GPT
-
SFO
1 stop9h 40m
American Airlines
Mon 3/162:33 pm
SFO
-
GPT
1 stop6h 26m
American Airlines
Deal found 1/26$334
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/102:44 pm
GPT
-
SFO
1 stop7h 49m
Delta
Mon 3/164:47 pm
SFO
-
GPT
2 stops14h 03m
Delta
Deal found 1/26$342
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/116:33 pm
GPT
-
SFO
1 stop6h 39m
American Airlines
Sun 2/1512:08 pm
SFO
-
GPT
1 stop8h 51m
American Airlines
Deal found 1/27$359
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:47 pm
GPT
-
SFO
1 stop6h 58m
American Airlines
Tue 6/165:22 am
SFO
-
GPT
1 stop10h 51m
American Airlines
Deal found 1/27$389
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/103:00 pm
GPT
-
SFO
1 stop10h 25m
Delta
Sat 2/1410:00 pm
SFO
-
GPT
1 stop9h 40m
Delta
Deal found 1/26$464
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:31 am
GPT
-
SFO
2 stops11h 34m
American Airlines
Sat 2/1411:35 pm
SFO
-
GPT
1 stop8h 38m
American Airlines
Deal found 1/26$469
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:43 am
GPT
-
SFO
2 stops12h 40m
American Airlines
Sat 2/2811:35 pm
SFO
-
GPT
2 stops10h 59m
American Airlines
Deal found 1/27$548
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/1712:34 pm
GPT
-
SFO
1 stop11h 46m
American Airlines
Fri 2/202:27 pm
SFO
-
GPT
1 stop6h 32m
American Airlines
Deal found 1/27$577

Find flight deals from Biloxi to San Francisco

Keep the following information in mind while searching for Biloxi to San Francisco flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$309
(American Airlines)

Popular in

April

Cheapest in

August

Average price

$484
Provider with most accurate pricing for Gulfport Biloxi Regional-San Francisco flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-San Francisco flights.
Search Deals
From Biloxi to San Francisco
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from Biloxi to San Francisco that are best for you.

Fly from

Biloxi

Fly to

San Francisco

Route

Depart

Return

Price

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Thu 2/26

7:35 pm-12:48 am

1 stop7h 13m

San Francisco

Sat 2/28

11:35 pm-10:13 am

1 stop8h 38m

$309

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Thu 2/19

7:35 pm-12:48 am

1 stop7h 13m

San Francisco

Mon 2/23

11:35 pm-10:13 am

1 stop8h 38m

$309

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Tue 3/10

2:44 pm-8:33 pm

1 stop7h 49m

San Francisco

Mon 3/16

4:47 pm-8:50 am

2 stops14h 03m

$342

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Wed 2/11

6:33 pm-11:12 pm

1 stop6h 39m

San Francisco

Sun 2/15

12:08 pm-10:59 pm

1 stop8h 51m

$359

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Wed 6/10

7:47 pm-12:45 am

1 stop6h 58m

San Francisco

Tue 6/16

5:22 am-6:13 pm

1 stop10h 51m

$389

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Tue 2/10

3:00 pm-11:25 pm

1 stop10h 25m

San Francisco

Sat 2/14

10:00 pm-9:40 am

1 stop9h 40m

$464

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Tue 2/10

5:31 am-3:05 pm

2 stops11h 34m

San Francisco

Sat 2/14

11:35 pm-10:13 am

1 stop8h 38m

$469

GulfportSan Francisco

GPT - SFO

GPTSFO

Gulfport Biloxi Regional

Tue 3/10

10:43 am-6:30 pm

2 stops9h 47m

San Francisco

Mon 3/16

10:25 am-10:59 pm

2 stops10h 34m

$547

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Best time to book a flight from Biloxi to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to San Francisco

What is the cheapest month to book a flight from Biloxi to San Francisco?

Currently, March is the cheapest month in which you can book a flight from Biloxi to San Francisco (average of $182). Flying from Biloxi to San Francisco in January is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to SFO?

Find hourly flight availability from Biloxi to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 28, 2026.

Unlike in the afternoon, when flights are generally more expensive, you can save up to 23% on flights from Biloxi to San Francisco by exploring options for tickets at noon.

What is the cheapest day to fly from Biloxi to San Francisco?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to San Francisco. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Biloxi to San Francisco flight should consider departing on Thursday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Biloxi to San Francisco

Explore weekly flight availability from Biloxi to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 28, 2026.

The most flights from B1L to SFO are scheduled on a Monday (6 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Reviews of airlines servicing San Francisco

Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated January 28, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from Biloxi to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,212 reviews

Boarding

7.7

Food

6.6

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,212 reviews
United Airlines
7.4
Good
9,212 reviews

Boarding

7.7

Food

6.6

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.2
Good
11,201 reviews
United Airlines
7.4
Good
9,212 reviews

Boarding

7.7

Food

6.6

Overall

7.4

Comfort

7.3

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Francisco from Biloxi?

    If you book a flight to San Francisco from Biloxi, you will be flying to San Francisco, which is the city’s only airport. San Francisco (SFO) is located 11.8 mi from the center of San Francisco. There are 0 flights from Biloxi to San Francisco per day from 6 different airlines.

  • How popular is this Biloxi to San Francisco flight route?

    The Biloxi to San Francisco flight path was viewed by 50 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Biloxi to San Francisco?

    For as low as $309, American Airlines can have you in San Francisco from Biloxi in 7h 13m. The distance from Biloxi to San Francisco is about 1959 mi. This flight may include one or multiple stops.

  • What are the most reliable airlines from Biloxi to San Francisco?

    No one likes to see their flight delayed. When booking a flight from Biloxi to San Francisco consider choosing Emirates (84%), Virgin Australia (84%) or Air New Zealand (84%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Biloxi to San Francisco?

    Looking for the cheapest flight from Biloxi to San Francisco? While on average our users pay $394, our data indicates the cheapest price to be $165. The most popular route (Gulfport Biloxi Regional - San Francisco), is priced around $309.

  • Can I find deals for flights from Biloxi to San Francisco that include hotel bookings?

    Yes. In addition to deals on Biloxi to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to San Francisco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to San Francisco.

  • Can I find deals for business class flights from Biloxi to San Francisco?

    Yes. Cheapflights offers flight deals from Biloxi to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to San Francisco?

    Currently, March is the cheapest month in which you can book a flight from Biloxi to San Francisco (average of $182). Flying from Biloxi to San Francisco in January is currently the most expensive (average of $269). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Francisco?

Book flights to San Francisco if you plan to visit one of these locations
South San Francisco
Santa Cruz
Roseville
Santa Clara
Livermore
Watsonville
San Bruno
Daly City
Sunnyvale
Turlock
Vacaville
San Carlos
San Ramon
Manteca
Vallejo
San Lorenzo
Davis
Hollister
Redwood City
Union City

Browse thousands of different options on Cheapflights for your next trip

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Top 6 airlines flying from Biloxi to San Francisco

Discover the top 6 airlines that operate flights from Biloxi to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$130Average$238FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$192Average$436FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$329FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$268Average$391FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$278Average$404FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$296Average$494FlexibilityNo cancel feeOn-time75%

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