$339+ Cheap flights from South Padre Island, TX to San Diego (SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/11. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — SAN
Jun 12 — Jun 191
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from South Padre Island to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Padre Island to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from South Padre Island to San DiegoExplore the most affordable flight options available from South Padre Island to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
Explore the most affordable flight options available from South Padre Island to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 13, 2026.
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Wed 6/174:33 pm
SAN
- BRO
1 stop5h 50m
American Airlines
Deal found 5/12![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:44 pm
BRO
- SAN
1 stop6h 40m
United Airlines
Fri 6/56:15 am
SAN
- BRO
1 stop7h 42m
United Airlines
Deal found 5/10![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Fri 6/57:15 pm
SAN
- BRO
2 stops12h 59m
American Airlines
Deal found 5/10![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Mon 6/89:47 am
SAN
- BRO
2 stops12h 36m
American Airlines
Deal found 5/11![American Airlines logo]()
$412
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:20 am
BRO
- SAN
1 stop5h 57m
United Airlines
Sat 8/298:00 am
SAN
- BRO
1 stop5h 51m
United Airlines
Deal found 5/12![United Airlines logo]()
$419
This Expedia deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:47 pm
BRO
- SAN
1 stop7h 42m
Alaska Airlines
Wed 7/12:25 pm
SAN
- BRO
1 stop7h 58m
Alaska Airlines
Deal found 5/12![Alaska Airlines logo]()
$429
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Mon 5/251:55 pm
SAN
- BRO
1 stop8h 28m
American Airlines
Deal found 5/12![American Airlines logo]()
$458
Best flights from South Padre Island to San DiegoDiscover carefully curated flight deals from South Padre Island to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
Discover carefully curated flight deals from South Padre Island to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 13, 2026.
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Wed 6/1712:46 pm
SAN
- BRO
2 stops9h 37m
American Airlines
Deal found 5/12![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/259:20 am
BRO
- SAN
1 stop5h 57m
United Airlines
Sat 8/298:00 am
SAN
- BRO
1 stop5h 51m
United Airlines
Deal found 5/12![United Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Mon 6/1512:46 pm
SAN
- BRO
2 stops9h 37m
American Airlines
Deal found 5/10![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:47 pm
BRO
- SAN
1 stop7h 20m
American Airlines
Mon 5/2512:45 pm
SAN
- BRO
2 stops9h 38m
American Airlines
Deal found 5/12![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:42 pm
BRO
- SAN
1 stop7h 17m
American Airlines
Mon 6/14:33 pm
SAN
- BRO
1 stop5h 50m
American Airlines
Deal found 5/10![American Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:20 am
BRO
- SAN
1 stop5h 31m
United Airlines
Thu 5/2810:13 am
SAN
- BRO
1 stop6h 31m
United Airlines
Deal found 5/10![United Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/2310:44 am
BRO
- SAN
2 stops9h 35m
American Airlines
Wed 5/273:10 pm
SAN
- BRO
1 stop7h 13m
American Airlines
Deal found 5/10![American Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/232:43 pm
BRO
- SAN
2 stops8h 52m
American Airlines
Sun 10/256:15 am
SAN
- BRO
1 stop6h 01m
American Airlines
Deal found 5/12![American Airlines logo]()
$590
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Sun 5/314:33 pm
SAN
- BRO
1 stop5h 50m
American Airlines
Deal found 5/10![American Airlines logo]()
$625
Last-minute flights from South Padre Island to San DiegoDiscover last-minute flight deals from South Padre Island to San Diego. Data last updated May 13, 2026 and is based on user searches.
Discover last-minute flight deals from South Padre Island to San Diego. Data last updated May 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:20 am
BRO
- SAN
1 stop5h 43m
United Airlines
Tue 6/26:15 am
SAN
- BRO
1 stop7h 42m
United Airlines
Deal found 5/10![United Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:20 am
BRO
- SAN
1 stop8h 30m
United Airlines
Mon 6/17:41 pm
SAN
- BRO
2 stops13h 45m
United Airlines
Deal found 5/10![United Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Mon 5/251:55 pm
SAN
- BRO
1 stop8h 28m
American Airlines
Deal found 5/12![American Airlines logo]()
$458
This United Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/14:44 pm
BRO
- SAN
1 stop6h 40m
United Airlines
Fri 6/56:15 am
SAN
- BRO
1 stop7h 42m
United Airlines
Deal found 5/10![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Fri 6/57:15 pm
SAN
- BRO
2 stops12h 59m
American Airlines
Deal found 5/10![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Mon 6/89:47 am
SAN
- BRO
2 stops12h 36m
American Airlines
Deal found 5/11![American Airlines logo]()
$412
This American Airlines deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:42 pm
BRO
- SAN
1 stop5h 57m
American Airlines
Wed 6/174:33 pm
SAN
- BRO
1 stop5h 50m
American Airlines
Deal found 5/12![American Airlines logo]()
$339
This Expedia deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/242:47 pm
BRO
- SAN
1 stop7h 42m
Alaska Airlines
Wed 7/12:25 pm
SAN
- BRO
1 stop7h 58m
Alaska Airlines
Deal found 5/12![Alaska Airlines logo]()
$429
One-way flights from South Padre Island to San DiegoSearch for one-way flight options from South Padre Island to San Diego. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
Search for one-way flight options from South Padre Island to San Diego. Find affordable one-way fares based on user searches. Data last updated May 13, 2026.
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/74:44 pm
BRO
- SAN
2 stops9h 10m
United Airlines
Deal found 5/9![United Airlines logo]()
$495
Find flight deals from South Padre Island to San Diego
Keep the following information in mind while searching for South Padre Island to San Diego flight deals. Data was last updated May 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $339 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from South Padre Island to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
Use the filters below to find and compare flights from South Padre Island to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Thu 6/11
6:42 pm-10:39 pm
1 stop5h 57m
San Diego
Wed 6/17
12:46 pm-12:23 am
2 stops9h 37m
$358
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Fri 6/12
6:42 pm-10:39 pm
1 stop5h 57m
San Diego
Mon 6/15
12:46 pm-12:23 am
2 stops9h 37m
$404
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Tue 8/25
9:20 am-1:17 pm
1 stop5h 57m
San Diego
Sat 8/29
8:00 am-3:51 pm
1 stop5h 51m
$419
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Sat 5/23
2:47 pm-8:07 pm
1 stop7h 20m
San Diego
Mon 5/25
12:45 pm-12:23 am
2 stops9h 38m
$463
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Sat 5/23
6:42 pm-11:59 pm
1 stop7h 17m
San Diego
Mon 6/1
4:33 pm-12:23 am
1 stop5h 50m
$483
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Sat 5/23
10:44 am-6:19 pm
2 stops9h 35m
San Diego
Wed 5/27
3:10 pm-12:23 am
1 stop7h 13m
$518
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Fri 10/23
2:43 pm-9:35 pm
2 stops8h 52m
San Diego
Sun 10/25
6:15 am-2:16 pm
1 stop6h 01m
$590
Quickest round-trip
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Mon 5/25
6:42 pm-10:39 pm
1 stop5h 57m
San Diego
Sun 5/31
4:33 pm-12:23 am
1 stop5h 50m
$625
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Mon 5/25
7:20 am-10:51 am
1 stop5h 31m
San Diego
Thu 5/28
10:13 am-6:44 pm
1 stop6h 31m
$644
Cheapest one-way
Quickest one-way
BrownsvilleSan Diego
BRO - SAN
BROSAN
Brownsville South Padre Is. Intl
Sun 6/7
4:44 pm-11:54 pm
2 stops9h 10m
$495
Sorted by cheapest first
Best time to book a flight from South Padre Island to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from South Padre Island with our price prediction graph.
BRO-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Padre Island to San Diego
SO9-SAN
BRO-SAN
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated May 13, 2026.
Read through reviews of airlines operating flights from South Padre Island to San Diego, such as American Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.5
Food
6.4
Comfort
7.2
Entertainment
6.9
Crew
7.9
Overall
7.1
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Boarding
7.5
Food
6.4
Comfort
7.2
Entertainment
6.9
Crew
7.9
Overall
7.1
Reviews
1 / 20
2.0
MediocreAnonymous,Apr 2026
DFW - BDL
Related info for your journey
Find useful and relevant information for your journey from South Padre Island to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
Poway
La Mesa
Julian
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
San Diego flight routes
Top destinations
Alternative routes for South Padre Island to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Padre Island to San Diego by cabin class
Find flights from South Padre Island to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Padre Island and San Diego flights
Browse other South Padre Island and San Diego flight options. Last updated on May 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 13, 2026.
South Padre Island to San Diego flights
Consider these flights traveling from South Padre Island to San Diego.
Top 3 airlines flying from South Padre Island to San Diego
Discover the top 3 airlines that operate flights from South Padre Island to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$143 | Average$408 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$217 | Average$348 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$236 | Average$397 | FlexibilityNo cancel fee | On-time71% |