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$258+ Cheap flights from Santiago (SCL) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/26. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SAN
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Diego are usually found in August or November, booked 76 days in advance, depart on a Friday or Tuesday and return on a Sunday

Cheap flight deals from Santiago to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$454
(Copa Airlines)

One-way from

$258
(Copa Airlines)

Popular in

April

Cheapest in

August

Average price

$940
From Santiago Arturo Merino Benitez to San Diego
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One-way flight from Santiago Arturo Merino Benitez to San Diego
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Highest demand for flights based on searches. 15% potential increase in price ($164 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($30 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Santiago to San Diego

Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Copa Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:23 amSCL - SAN
1 stop18h 34mCopa Airlines
Mon 10/209:12 pmSAN - SCL
1 stop22h 52mCopa Airlines
Deal found 6/12$454
This LATAM Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/318:15 amSCL - SAN
1 stop18h 39mLATAM Airlines
Thu 11/1311:00 amSAN - SCL
1 stop15h 00mLATAM Airlines
Deal found 6/11$777
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1010:50 pmSCL - SAN
2 stops21h 48mDelta
Tue 1/66:20 amSAN - SCL
2 stops18h 40mDelta
Deal found 6/10$795
This United Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/110:45 pmSCL - SAN
2 stops23h 44mUnited Airlines
Thu 11/131:47 pmSAN - SCL
1 stop14h 03mUnited Airlines
Deal found 6/11$803
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2011:15 pmSCL - SAN
1 stop15h 12mAmerican Airlines
Fri 1/1610:56 amSAN - SCL
1 stop15h 54mAmerican Airlines
Deal found 6/11$821
This eDestinos deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/232:23 amSCL - SAN
1 stop18h 21mMultiple Airlines
Fri 9/512:32 pmSAN - SCL
3 stops35h 11mMultiple Airlines
Deal found 6/10$850

Cheapflights Fare Finder

Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Santiago

Fly to

San Diego

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 10/7

3:23 am-5:57 pm

1 stop18h 34m

San Diego

Mon 10/20

9:12 pm-12:04 am

1 stop22h 52m

$454

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 10/31

8:15 am-10:54 pm

1 stop18h 39m

San Diego

Thu 11/13

11:00 am-7:00 am

1 stop15h 00m

$777

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/1

10:45 pm-6:29 pm

2 stops23h 44m

San Diego

Thu 11/13

1:47 pm-8:50 am

1 stop14h 03m

$803

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 10/31

9:55 pm-8:49 pm

1 stop26h 54m

San Diego

Thu 11/13

7:00 am-7:00 am

1 stop19h 00m

$805

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 8/23

2:23 am-5:44 pm

1 stop18h 21m

San Diego

Fri 9/5

12:32 pm-2:43 am

3 stops35h 11m

$850

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 7/3

9:55 pm-5:57 pm

2 stops23h 02m

San Diego

Fri 7/11

8:18 am-7:05 am

2 stops19h 47m

$1,056

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 9/26

5:10 am-5:50 pm

1 stop16h 40m

$258

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 9/24

7:10 am-11:36 am

3 stops32h 26m

$360

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 10/21

8:15 am-10:54 pm

1 stop18h 39m

$518

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 11/20

10:45 pm-8:28 pm

3 stops26h 43m

$576

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/12

Showing 1-10 of 11 results
1
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Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Diego. Price data was last updated on June 9, 2025.

Booking 75 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to San Diego?

Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in San Diego by month

Plan your trip to San Diego by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Diego ranges from 0.0 - 2.3 inches per month. February is typically the wettest month, when rainfall can reach 2.3 in. July is typically the driest time to visit San Diego when rainfall is around 0.0 in.

Temperature in San Diego by month

Plan your trip to San Diego by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Diego, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 71.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 57.2 F).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Delta, LATAM Airlines and Copa Airlines from Santiago to San Diego. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
LATAM Airlines
7.5
Good
1,785 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Boarding

8.2

Food

7.3

Crew

8.5

Comfort

7.9

Overall

8.0

Entertainment

7.9

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santiago to San Diego round-trip?

    Our cheapest airline available from Santiago to San Diego is Copa Airlines. Our recent data shows that you can find tickets from as low as $454 on this airline. Additional options worth looking into are LATAM Airlines and United Airlines, starting at $777 and $803 round-trip. Copa Airlines is currently priced 50% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Santiago to San Diego one-way?

    To fly one-way, consider booking your trip with Copa Airlines, which is currently one of the cheapest options available, starting at $258. LATAM Airlines flights start at $518 while deals on United Airlines start at $576 one-way.

  • Can I find deals for flights from Santiago to San Diego that include hotel bookings?

    Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.

  • Can I find deals for business class flights from Santiago to San Diego?

    Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Imperial Beach
La Mesa
Alpine
Lemon Grove
Poway
Santee
Coronado

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Top 2 airlines flying from Santiago to San Diego

Discover the top 2 airlines that operate flights from Santiago to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$702Average$917FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$803Average$933FlexibilityNo cancel feeOn-time81%

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