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$339+ Cheap flights from Santiago (SCL) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SAN
Jul 5 — Jul 121
Sun 7/5
Sun 7/12
1 adult, Economy
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Cheap flight deals from Santiago to San Diego

Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 5, 2026.

This eDestinos deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2211:25 pm
SCL
-
SAN
1 stop16h 05m
LATAM Airlines
Tue 12/13:59 pm
SAN
-
SCL
2 stops17h 06m
LATAM Airlines
Deal found 6/3$571
This Despegar deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/1711:25 pm
SCL
-
SAN
1 stop18h 45m
LATAM Airlines
Wed 9/212:32 pm
SAN
-
SCL
1 stop15h 43m
LATAM Airlines
Deal found 6/2$596
This Despegar deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Despegar is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1511:25 pm
SCL
-
SAN
1 stop18h 45m
LATAM Airlines
Wed 9/212:32 pm
SAN
-
SCL
1 stop15h 43m
LATAM Airlines
Deal found 6/3$598
This eDestinos deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:40 pm
SCL
-
SAN
1 stop17h 57m
LATAM Airlines
Mon 7/1310:54 am
SAN
-
SCL
1 stop15h 41m
LATAM Airlines
Deal found 6/1$599
This Atrapalo deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Atrapalo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/2212:25 am
SCL
-
SAN
1 stop19h 55m
LATAM Airlines
Tue 12/13:59 pm
SAN
-
SCL
2 stops18h 06m
LATAM Airlines
Deal found 6/2$600
This eDestinos deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:25 pm
SCL
-
SAN
1 stop22h 54m
LATAM Airlines
Wed 9/26:15 am
SAN
-
SCL
1 stop22h 00m
LATAM Airlines
Deal found 6/1$601
This eDestinos deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:25 pm
SCL
-
SAN
1 stop24h 30m
LATAM Airlines
Sun 12/68:00 am
SAN
-
SCL
2 stops16h 35m
LATAM Airlines
Deal found 6/1$603
This eDestinos deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:40 pm
SCL
-
SAN
1 stop17h 27m
LATAM Airlines
Sun 8/306:15 am
SAN
-
SCL
1 stop20h 20m
LATAM Airlines
Deal found 6/1$605
This Copa Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/201:02 am
SCL
-
SAN
1 stop21h 13m
Copa Airlines
Mon 11/3010:00 pm
SAN
-
SCL
1 stop24h 43m
Copa Airlines
Deal found 6/2$608

Find flight deals from Santiago to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 5, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$596
(Despegar)

One-way from

$339
(Kiwi.com)

Popular in

January

Cheapest in

August

Average price

$1,070
Provider with most accurate pricing for Santiago Arturo Merino Benitez-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-San Diego flights.
Search Deals
From Santiago Arturo Merino Benitez to San Diego
Search Deals
One-way flight from Santiago Arturo Merino Benitez to San Diego
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($118 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 5, 2026.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/21

5:07 am-5:15 pm

1 stop17h 08m

San Diego

Sun 12/6

10:00 pm-8:11 pm

1 stop17h 11m

$608

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/21

11:25 pm-10:55 pm

1 stop28h 30m

San Diego

Sun 12/6

6:15 am-6:50 am

2 stops19h 35m

$611

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/24

11:25 pm-11:54 pm

1 stop27h 29m

San Diego

Sun 8/30

6:15 am-5:35 am

2 stops20h 20m

$611

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 9/29

8:40 pm-9:10 pm

1 stop28h 30m

San Diego

Tue 10/6

8:00 am-6:55 am

2 stops18h 55m

$611
Quickest round-trip

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 6/23

11:25 pm-3:11 pm

1 stop18h 46m

San Diego

Tue 7/7

12:59 pm-7:15 am

1 stop15h 16m

$611

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Mon 8/3

11:00 pm-5:05 pm

2 stops21h 05m

San Diego

Mon 8/17

6:15 am-6:25 am

2 stops21h 10m

$611

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 11/3

11:10 pm-8:18 pm

1 stop26h 08m

San Diego

Sat 11/14

9:40 pm-7:40 am

1 stop29h 00m

$611

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Sat 11/21

10:45 pm-5:10 pm

2 stops23h 25m

San Diego

Sun 12/6

7:00 am-8:50 am

2 stops20h 50m

$612

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 11/3

10:45 pm-11:08 am

2 stops17h 23m

San Diego

Sat 11/14

6:30 pm-8:50 am

2 stops33h 20m

$612
Cheapest one-way

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Tue 7/28

6:40 am-12:04 am

3 stops44h 24m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/3

Showing 1-10 of 16 resultsSorted by cheapest first
1
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Compare providers for flights from Santiago to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Diego in June.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Booking 74 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to San Diego?

Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $502). Flying from Santiago to San Diego in January is currently the most expensive (average of $1,089). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santiago to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to San Diego?

    Departing from Santiago to San Diego will take you 20h 47m. Airlines will cover a distance of 5471 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Santiago to San Diego one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $332. Delta flights start at $347 while deals on American Airlines start at $351 one-way.

  • Can I find deals for flights from Santiago to San Diego that include hotel bookings?

    Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.

  • Can I find deals for business class flights from Santiago to San Diego?

    Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $502). Flying from Santiago to San Diego in January is currently the most expensive (average of $1,089). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Poway
Coronado
La Mesa
Santee
Julian
Lemon Grove

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