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$562+ Cheap flights from Santiago (SCL) to San Diego (SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/6. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SAN
Mar 25 — Apr 11
Wed 3/25
Wed 4/1
1 adult, Economy
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Cheap flight deals from Santiago to San Diego

Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.

This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:00 pm
SCL
-
SAN
2 stops24h 36m
Delta
Mon 4/136:15 am
SAN
-
SCL
2 stops21h 35m
Delta
Deal found 2/20$562
This LATAM Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/84:30 pm
SCL
-
SAN
2 stops33h 39m
LATAM Airlines
Wed 4/152:10 pm
SAN
-
SCL
2 stops19h 55m
LATAM Airlines
Deal found 2/22$570
This LATAM Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:30 pm
SCL
-
SAN
2 stops33h 39m
LATAM Airlines
Thu 4/910:40 am
SAN
-
SCL
1 stop15h 55m
LATAM Airlines
Deal found 2/22$571
This LATAM Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:00 pm
SCL
-
SAN
2 stops22h 51m
LATAM Airlines
Mon 4/1311:02 am
SAN
-
SCL
3 stops22h 38m
LATAM Airlines
Deal found 2/20$576
This Copa Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:49 am
SCL
-
SAN
1 stop16h 41m
Copa Airlines
Sun 4/199:18 pm
SAN
-
SCL
1 stop23h 08m
Copa Airlines
Deal found 2/19$579
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:35 pm
SCL
-
SAN
1 stop18h 18m
American Airlines
Sun 5/1012:53 pm
SAN
-
SCL
1 stop15h 12m
American Airlines
Deal found 2/22$590
This Copa Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2312:09 am
SCL
-
SAN
1 stop21h 21m
Copa Airlines
Sun 5/1010:00 pm
SAN
-
SCL
1 stop21h 43m
Copa Airlines
Deal found 2/21$601
This LATAM Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:40 pm
SCL
-
SAN
1 stop16h 09m
LATAM Airlines
Sun 5/1011:01 am
SAN
-
SCL
1 stop15h 34m
LATAM Airlines
Deal found 2/20$608
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1210:15 pm
SCL
-
SAN
1 stop26h 22m
American Airlines
Mon 3/236:15 am
SAN
-
SCL
1 stop20h 45m
American Airlines
Deal found 2/22$612

Find flight deals from Santiago to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$562
(Delta)

Popular in

January

Cheapest in

August

Average price

$829
Provider with most accurate pricing for Santiago Arturo Merino Benitez-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Santiago Arturo Merino Benitez-San Diego flights.
Search Deals
From Santiago Arturo Merino Benitez to San Diego
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($92 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Santiago

Fly to

San Diego

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 4/3

5:49 am-6:30 pm

1 stop16h 41m

San Diego

Sun 4/19

9:18 pm-11:26 pm

1 stop23h 08m

$579

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 4/23

12:09 am-6:30 pm

1 stop21h 21m

San Diego

Sun 5/10

10:00 pm-7:23 pm

1 stop18h 23m

$624

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 3/12

9:45 pm-3:00 pm

2 stops21h 15m

San Diego

Mon 3/23

11:03 am-7:50 am

2 stops16h 47m

$626

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 5/28

12:38 am-6:30 pm

1 stop20h 52m

San Diego

Sun 6/14

9:06 pm-10:43 pm

1 stop22h 37m

$643

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 3/6

6:30 pm-10:11 am

2 stops20h 41m

San Diego

Tue 3/10

6:15 am-5:55 am

2 stops19h 40m

$646

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Thu 3/5

11:10 pm-10:48 pm

1 stop28h 38m

San Diego

Wed 3/11

7:00 am-5:55 am

1 stop18h 55m

$647

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 3/6

11:10 pm-10:11 am

1 stop16h 01m

San Diego

Sun 3/8

10:25 pm-5:55 am

1 stop27h 30m

$647

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Fri 3/6

11:10 pm-10:48 pm

1 stop28h 38m

San Diego

Mon 3/9

7:00 am-5:55 am

1 stop18h 55m

$647

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 3/4

8:55 pm-9:47 am

2 stops41h 52m

$1,156

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

Wed 3/4

11:10 pm-10:01 am

1 stop15h 51m

$1,238

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/21

Showing 1-10 of 11 results
1
2

Compare providers for flights from Santiago to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santiago to San Diego in February.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*2 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Santiago-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santiago-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santiago-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Santiago-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santiago-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Diego. Price data was last updated on February 20, 2026.

Booking 37 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to San Diego?

Currently, October is the cheapest month in which you can book a flight from Santiago to San Diego (average of $292). Flying from Santiago to San Diego in January is currently the most expensive (average of $817). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated February 23, 2026.
Get a feel of what it's like to fly with LATAM Airlines from Santiago to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,919 reviews

Crew

8.0

Boarding

7.5

Food

6.7

Overall

7.5

Comfort

7.3

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken
LATAM Airlines
7.5
Good
1,919 reviews
LATAM Airlines
7.5
Good
1,919 reviews

Crew

8.0

Boarding

7.5

Food

6.7

Overall

7.5

Comfort

7.3

Entertainment

7.0

Reviews

1 / 20
2.0
Mediocre

Jess,Jan 2026

GRU - MIA

sat on the tarmac for 4.5 hours with no explanation, climate control, honesty about the timeline or the situation, or even letting anyone off. The crew was passive-aggressive and sneaky, trying to skirt legal time limits requiring financial restitution for passengers, pretending the "flight had started" even though they didn't budge for another 40 minutes. One of the worst flights I've ever taken

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to San Diego?

    Departing from Santiago to San Diego will take you 16h 41m. Airlines will cover a distance of 5471 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Santiago to San Diego round-trip?

    Our cheapest airline available from Santiago to San Diego is LATAM Airlines. Our recent data shows that you can find tickets from as low as $497 on this airline. LATAM Airlines is currently priced 38% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Santiago to San Diego one-way?

    To fly one-way, consider booking your trip with LATAM Airlines, which is currently one of the cheapest options available, starting at $332. Delta flights start at $347 while deals on American Airlines start at $351 one-way.

  • Can I find deals for flights from Santiago to San Diego that include hotel bookings?

    Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.

  • Can I find deals for business class flights from Santiago to San Diego?

    Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Diego?

    Currently, October is the cheapest month in which you can book a flight from Santiago to San Diego (average of $292). Flying from Santiago to San Diego in January is currently the most expensive (average of $817). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Santiago to San Diego

Discover the top airline that operate flights from Santiago to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapest$497Average$933FlexibilityNo cancel feeOn-time81%

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