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$281+ Cheap flights from Santiago (SCL) to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/17. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SAN
ago. 19 — ago. 261
mar. 8/19
mar. 8/26
1 adult, Economy
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Cheapflights Tip: The best prices from Santiago Arturo Merino Benitez to San Diego are usually found in August or November, booked 37 days in advance, depart on a Friday or Tuesday and return on a Sunday

Cheap flight deals from Santiago to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 14, 2025.

Round-trip from

$497
(FlightHub)

One-way from

$281
(LATAM Airlines)

Popular in

April

Cheapest in

August

Average price

$502
From Santiago Arturo Merino Benitez to San Diego
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One-way flight from Santiago Arturo Merino Benitez to San Diego
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Highest demand for flights based on searches. 15% potential increase in price ($159 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Santiago to San Diego

Cheapest flights from Santiago to San Diego
Explore the most affordable flight options available from Santiago to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 14, 2025.

This FlightHub deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/3011:05 pmSCL - SAN
1 stop14h 14mLATAM Airlines
jue. 10/3012:00 pmSAN - SCL
1 stop15h 40mLATAM Airlines
Deal found 8/12$497
This LATAM Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/2411:05 pmSCL - SAN
1 stop14h 14mLATAM Airlines
mié. 10/812:00 pmSAN - SCL
1 stop15h 00mLATAM Airlines
Deal found 8/12$504
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/2411:05 pmSCL - SAN
1 stop24h 01mDelta
mié. 10/86:25 amSAN - SCL
2 stops20h 25mDelta
Deal found 8/12$505
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/111:25 pmSCL - SAN
2 stops24h 14mDelta
jue. 12/46:20 amSAN - SCL
1 stop19h 40mDelta
Deal found 8/12$506
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 8/248:40 pmSCL - SAN
1 stop27h 35mDelta
vie. 9/56:25 amSAN - SCL
1 stop21h 35mDelta
Deal found 8/14$509
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2910:10 pmSCL - SAN
1 stop18h 25mDelta
dom. 11/25:15 amSAN - SCL
1 stop20h 25mDelta
Deal found 8/11$514
This LATAM Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/111:55 pmSCL - SAN
1 stop14h 24mLATAM Airlines
mié. 12/311:00 amSAN - SCL
1 stop15h 00mLATAM Airlines
Deal found 8/12$515
This LATAM Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/2312:25 amSCL - SAN
2 stops21h 45mLATAM Airlines
dom. 11/96:20 amSAN - SCL
2 stops28h 10mLATAM Airlines
Deal found 8/13$517
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/229:55 pmSCL - SAN
2 stops24h 08mAmerican Airlines
lun. 9/297:13 amSAN - SCL
2 stops20h 42mAmerican Airlines
Deal found 8/12$518

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
Use the filters below to find and compare flights from Santiago to San Diego that are best for you.

Fly from

Santiago

Fly to

San Diego

Route

Depart

Return

Price

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

mar. 9/30

11:05 pm-9:19 am

1 stop14h 14m

San Diego

jue. 10/30

12:00 pm-7:40 am

1 stop15h 40m

$497

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

mié. 9/24

11:05 pm-9:19 am

1 stop14h 14m

San Diego

mié. 10/8

12:00 pm-7:00 am

1 stop15h 00m

$504

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

mié. 9/17

11:05 pm-3:25 pm

1 stop20h 20m

San Diego

mié. 9/24

10:55 am-7:00 am

1 stop16h 05m

$504

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

mié. 9/24

11:05 pm-9:19 am

1 stop14h 14m

San Diego

dom. 11/9

6:20 am-7:00 am

1 stop19h 40m

$504

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

mar. 9/30

11:30 pm-3:26 pm

2 stops19h 56m

San Diego

jue. 10/30

6:15 am-6:00 am

2 stops19h 45m

$505

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

sáb. 9/27

11:05 pm-3:25 pm

1 stop20h 20m

San Diego

sáb. 10/4

10:30 pm-7:00 am

1 stop28h 30m

$505

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

vie. 10/31

10:10 pm-6:32 pm

1 stop24h 22m

San Diego

jue. 11/13

10:40 pm-6:00 am

2 stops26h 20m

$505

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

lun. 9/22

9:40 pm-7:27 pm

1 stop25h 47m

San Diego

lun. 9/29

10:30 pm-7:00 am

1 stop28h 30m

$505

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

mié. 9/24

9:40 pm-9:30 am

1 stop15h 50m

San Diego

dom. 11/9

10:40 pm-6:00 am

2 stops26h 20m

$505

SantiagoSan Diego

SCL - SAN

SCLSAN

Santiago Arturo Merino Benitez

mié. 9/17

11:05 pm-9:19 am

1 stop14h 14m

$281

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 16 results
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Best time to book a flight from Santiago to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to San Diego

How far ahead should I book a flight from Santiago to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to San Diego. Price data was last updated on August 8, 2025.

Booking 37 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to San Diego?

Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated agosto 14, 2025.
Get a feel of what it's like to fly with Delta and LATAM Airlines from Santiago to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
LATAM Airlines
7.5
Good
1,840 reviews
Delta
8.0
Very good
7,980 reviews

Boarding

8.2

Overall

8.0

Entertainment

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Santiago to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Santiago to San Diego round-trip?

    Our cheapest airline available from Santiago to San Diego is Delta. Our recent data shows that you can find tickets from as low as $702 on this airline. An additional option worth looking into is LATAM Airlines, starting at $803. Delta is currently priced 21% below the average price you’ll pay for this route.

  • Can I find deals for flights from Santiago to San Diego that include hotel bookings?

    Yes. In addition to deals on Santiago to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to San Diego.

  • Can I find deals for business class flights from Santiago to San Diego?

    Yes. Cheapflights offers flight deals from Santiago to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Santiago to San Diego (average of $286). Flying from Santiago to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
National City
Lemon Grove
Imperial Beach
Alpine

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Santiago to San Diego

Discover the top 2 airlines that operate flights from Santiago to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$702Average$853FlexibilityNo cancel feeOn-timeN/A
LATAM AirlinesCheapest$803Average$933FlexibilityNo cancel feeOn-time81%

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