$200+ Cheap flights from Portland, ME to San Diego (PWM - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/5. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — SAN
May 5 — May 121
Round-trip
1 adult, Economy
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Find cheap flights from Portland to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Portland to San Diego
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Best
Last-minute
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Cheapest flights from Portland to San DiegoExplore the most affordable flight options available from Portland to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 5, 2026.
Explore the most affordable flight options available from Portland to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:29 am
PWM
- SAN
2 stops39h 21m
Multiple Airlines
Mon 5/1112:33 pm
SAN
- PWM
1 stop22h 58m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$344
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
PWM
- SAN
1 stop8h 21m
United Airlines
Wed 6/312:57 pm
SAN
- PWM
1 stop7h 54m
United Airlines
Deal found 4/4![United Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:24 pm
PWM
- SAN
1 stop10h 24m
American Airlines
Wed 6/39:50 am
SAN
- PWM
2 stops9h 57m
American Airlines
Deal found 4/4![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:02 pm
PWM
- SAN
1 stop10h 47m
American Airlines
Tue 5/56:15 am
SAN
- PWM
1 stop9h 23m
American Airlines
Deal found 4/1![American Airlines logo]()
$410
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:11 pm
PWM
- SAN
1 stop23h 37m
Breeze Airways
Mon 5/1112:33 pm
SAN
- PWM
1 stop22h 58m
Breeze Airways
Deal found 4/5![Breeze Airways logo]()
$414
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:00 pm
PWM
- SAN
2 stops11h 00m
Southwest
Sat 6/66:35 am
SAN
- PWM
2 stops11h 25m
Southwest
Deal found 4/2![Southwest logo]()
$420
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:43 pm
PWM
- SAN
1 stop9h 23m
Delta
Mon 5/111:10 pm
SAN
- PWM
1 stop8h 33m
Delta
Deal found 4/5![Delta logo]()
$421
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:25 am
PWM
- SAN
1 stop20h 17m
Delta
Mon 5/111:10 pm
SAN
- PWM
1 stop8h 33m
Delta
Deal found 4/5![Delta logo]()
$422
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:30 am
PWM
- SAN
1 stop10h 00m
Southwest
Mon 5/46:50 am
SAN
- PWM
1 stop13h 35m
Southwest
Deal found 4/5![Southwest logo]()
$426
Best flights from Portland to San DiegoDiscover carefully curated flight deals from Portland to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 5, 2026.
Discover carefully curated flight deals from Portland to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 5, 2026.
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:00 pm
PWM
- SAN
2 stops9h 55m
Southwest
Sat 6/61:05 pm
SAN
- PWM
1 stop7h 35m
Southwest
Deal found 4/2![Southwest logo]()
$415
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/412:46 pm
PWM
- SAN
2 stops13h 56m
Delta
Mon 5/1110:25 pm
SAN
- PWM
2 stops10h 30m
Delta
Deal found 4/4![Delta logo]()
$431
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:15 am
PWM
- SAN
1 stop8h 34m
United Airlines
Wed 6/310:30 pm
SAN
- PWM
1 stop7h 41m
United Airlines
Deal found 4/2![United Airlines logo]()
$509
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:51 pm
PWM
- SAN
2 stops11h 34m
Delta
Tue 5/56:15 am
SAN
- PWM
2 stops14h 08m
Delta
Deal found 4/4![Delta logo]()
$449
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2110:30 am
PWM
- SAN
1 stop9h 40m
Southwest
Sat 9/2610:40 pm
SAN
- PWM
2 stops11h 05m
Southwest
Deal found 4/4![Southwest logo]()
$492
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2412:55 pm
PWM
- SAN
2 stops13h 20m
Delta
Thu 5/286:15 am
SAN
- PWM
2 stops13h 54m
Delta
Deal found 4/2![Delta logo]()
$464
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/112:50 pm
PWM
- SAN
2 stops11h 05m
Southwest
Sun 5/1710:30 pm
SAN
- PWM
2 stops10h 40m
Southwest
Deal found 4/1![Southwest logo]()
$500
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:00 am
PWM
- SAN
2 stops12h 19m
Delta
Thu 8/137:30 pm
SAN
- PWM
2 stops12h 19m
Delta
Deal found 4/4![Delta logo]()
$483
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:43 pm
PWM
- SAN
2 stops9h 55m
Delta
Fri 6/121:05 pm
SAN
- PWM
1 stop8h 47m
Delta
Deal found 4/2![Delta logo]()
$495
Last-minute flights from Portland to San DiegoDiscover last-minute flight deals from Portland to San Diego. Data last updated April 5, 2026 and is based on user searches.
Discover last-minute flight deals from Portland to San Diego. Data last updated April 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:02 pm
PWM
- SAN
1 stop10h 47m
American Airlines
Tue 5/56:15 am
SAN
- PWM
1 stop9h 23m
American Airlines
Deal found 4/1![American Airlines logo]()
$410
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:30 am
PWM
- SAN
1 stop10h 00m
Southwest
Mon 5/46:50 am
SAN
- PWM
1 stop13h 35m
Southwest
Deal found 4/5![Southwest logo]()
$426
This Delta deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/302:51 pm
PWM
- SAN
2 stops11h 34m
Delta
Tue 5/56:15 am
SAN
- PWM
2 stops14h 08m
Delta
Deal found 4/4![Delta logo]()
$449
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/411:29 am
PWM
- SAN
2 stops39h 21m
Multiple Airlines
Mon 5/1112:33 pm
SAN
- PWM
1 stop22h 58m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:43 pm
PWM
- SAN
1 stop9h 23m
Delta
Mon 5/111:10 pm
SAN
- PWM
1 stop8h 33m
Delta
Deal found 4/5![Delta logo]()
$421
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/43:02 pm
PWM
- SAN
1 stop10h 47m
American Airlines
Mon 5/1110:30 pm
SAN
- PWM
1 stop8h 48m
American Airlines
Deal found 4/4![American Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/73:11 pm
PWM
- SAN
1 stop23h 37m
Breeze Airways
Mon 5/1112:33 pm
SAN
- PWM
1 stop22h 58m
Breeze Airways
Deal found 4/5![Breeze Airways logo]()
$414
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:25 am
PWM
- SAN
1 stop20h 17m
Delta
Mon 5/111:10 pm
SAN
- PWM
1 stop8h 33m
Delta
Deal found 4/5![Delta logo]()
$422
One-way flights from Portland to San DiegoSearch for one-way flight options from Portland to San Diego. Find affordable one-way fares based on user searches. Data last updated April 5, 2026.
Search for one-way flight options from Portland to San Diego. Find affordable one-way fares based on user searches. Data last updated April 5, 2026.
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/51:18 pm
PWM
- SAN
1 stop9h 51m
American Airlines
Deal found 4/3![American Airlines logo]()
$200
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/252:51 pm
PWM
- SAN
1 stop11h 02m
Delta
Deal found 4/2![Delta logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:18 pm
PWM
- SAN
3 stops52h 43m
Multiple Airlines
Deal found 4/3![Multiple Airlines logo]()
$210
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:51 pm
PWM
- SAN
1 stop8h 56m
Delta
Deal found 4/2![Delta logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:47 am
PWM
- SAN
2 stops40h 19m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:56 pm
PWM
- SAN
3 stops49h 03m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$224
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/242:51 pm
PWM
- SAN
1 stop12h 04m
Delta
Deal found 4/2![Delta logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:00 am
PWM
- SAN
2 stops40h 58m
Multiple Airlines
Deal found 4/4![Multiple Airlines logo]()
$241
Find flight deals from Portland to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Portland (PWM) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $344 (Kiwi.com) |
One-way from | $200 (American Airlines) |
Popular in | December |
Cheapest in | September |
Average price | $531 |
Cheapflights Fare Finder
Customize your flight search to find flights from Portland to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 5, 2026.
Use the filters below to find and compare flights from Portland to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Tue 6/2
1:00 pm-7:55 pm
2 stops9h 55m
San Diego
Sat 6/6
1:05 pm-11:40 pm
1 stop7h 35m
$415
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Mon 5/4
12:46 pm-11:42 pm
2 stops13h 56m
San Diego
Mon 5/11
10:25 pm-11:55 am
2 stops10h 30m
$431
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Thu 4/30
2:51 pm-11:25 pm
2 stops11h 34m
San Diego
Tue 5/5
6:15 am-11:23 pm
2 stops14h 08m
$449
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Sun 5/24
12:55 pm-11:15 pm
2 stops13h 20m
San Diego
Thu 5/28
6:15 am-11:09 pm
2 stops13h 54m
$464
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Wed 8/12
6:00 am-3:19 pm
2 stops12h 19m
San Diego
Thu 8/13
7:30 pm-10:49 am
2 stops12h 19m
$483
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Mon 9/21
10:30 am-5:10 pm
1 stop9h 40m
San Diego
Sat 9/26
10:40 pm-12:45 pm
2 stops11h 05m
$492
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Mon 5/4
4:43 pm-11:38 pm
2 stops9h 55m
San Diego
Fri 6/12
1:05 pm-12:52 am
1 stop8h 47m
$495
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Mon 5/11
2:50 pm-10:55 pm
2 stops11h 05m
San Diego
Sun 5/17
10:30 pm-12:10 pm
2 stops10h 40m
$500
Quickest round-trip
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Tue 6/2
5:15 am-10:49 am
1 stop8h 34m
San Diego
Wed 6/3
10:30 pm-9:11 am
1 stop7h 41m
$509
Cheapest one-way
PortlandSan Diego
PWM - SAN
PWMSAN
Portland
Tue 5/5
6:00 am-2:05 pm
2 stops11h 05m
$205
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Portland to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Portland to San Diego in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Portland, Maine-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Portland, Maine-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Portland, Maine-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Portland, Maine-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Portland, Maine-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Portland to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Portland with our price prediction graph.
PWM-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Portland to San Diego
How far ahead should I book a flight from Portland, Maine to San Diego?
Use this chart to determine the optimal time to book a round-trip flight from Portland to San Diego. Price data was last updated on April 3, 2026.
To ensure you get the cheapest price possible for a flight from Portland, Maine to San Diego, you should look to book at least 84 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Portland, Maine to San Diego?
Currently, November is the cheapest month in which you can book a flight from Portland, Maine to San Diego (average of $123). Flying from Portland, Maine to San Diego in February is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Portland, Maine to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 5, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Portland to San Diego. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Comfort
8.0
Overall
8.0
Entertainment
7.5
Crew
8.6
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Portland to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
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Search flights from Portland to San Diego by cabin class
Find flights from Portland to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Portland and San Diego flights
Browse other Portland and San Diego flight options. Last updated on April 5, 2026.
Other flights from Portland
Browse through other flights departing from Portland. Flights are based on user searches made on Cheapflights and were last updated on April 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 5, 2026.
Top 4 airlines flying from Portland to San Diego
Discover the top 4 airlines that operate flights from Portland to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$311 | Average$467 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$318 | Average$461 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$325 | Average$486 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$350 | Average$527 | FlexibilityNo cancel fee | On-time69% |