$109+ Cheap flights from McAllen to San Diego (MFE - SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/13. Fares are subject to change and may not be available on all flights or dates of travel.
MFE — SAN
May 7 — May 141
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from McAllen to San Diego
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Best
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Cheapest flights from McAllen to San DiegoExplore the most affordable flight options available from McAllen to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
Explore the most affordable flight options available from McAllen to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:23 pm
MFE
- SAN
1 stop10h 49m
Multiple Airlines
Thu 6/119:53 pm
SAN
- MFE
1 stop11h 40m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:23 pm
MFE
- SAN
2 stops7h 13m
Delta
Sun 5/39:45 pm
SAN
- MFE
2 stops12h 38m
Delta
Deal found 4/3![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
MFE
- SAN
2 stops9h 57m
United Airlines
Mon 4/273:04 pm
SAN
- MFE
1 stop5h 55m
United Airlines
Deal found 4/3![United Airlines logo]()
$302
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/174:53 pm
MFE
- SAN
1 stop6h 05m
Multiple Airlines
Sat 6/209:53 pm
SAN
- MFE
1 stop12h 15m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$307
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:23 pm
MFE
- SAN
2 stops7h 13m
Delta
Mon 4/2710:30 pm
SAN
- MFE
2 stops11h 53m
Delta
Deal found 4/3![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:00 am
MFE
- SAN
1 stop6h 04m
United Airlines
Wed 4/293:04 pm
SAN
- MFE
1 stop5h 55m
United Airlines
Deal found 4/5![United Airlines logo]()
$312
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:32 pm
MFE
- SAN
1 stop6h 24m
American Airlines
Sun 5/174:41 pm
SAN
- MFE
1 stop5h 18m
American Airlines
Deal found 4/4![American Airlines logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:45 pm
MFE
- SAN
1 stop8h 15m
American Airlines
Sun 5/36:15 am
SAN
- MFE
1 stop7h 10m
American Airlines
Deal found 4/2![American Airlines logo]()
$327
Best flights from McAllen to San DiegoDiscover carefully curated flight deals from McAllen to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
Discover carefully curated flight deals from McAllen to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/812:23 pm
MFE
- SAN
1 stop10h 49m
Multiple Airlines
Thu 6/119:53 pm
SAN
- MFE
1 stop11h 40m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$280
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:23 pm
MFE
- SAN
2 stops7h 13m
Delta
Sun 5/39:45 pm
SAN
- MFE
2 stops12h 38m
Delta
Deal found 4/3![Delta logo]()
$291
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
MFE
- SAN
2 stops9h 57m
United Airlines
Mon 4/273:04 pm
SAN
- MFE
1 stop5h 55m
United Airlines
Deal found 4/3![United Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:23 pm
MFE
- SAN
2 stops7h 13m
Delta
Mon 4/2710:30 pm
SAN
- MFE
2 stops11h 53m
Delta
Deal found 4/3![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:00 am
MFE
- SAN
1 stop6h 04m
United Airlines
Wed 4/293:04 pm
SAN
- MFE
1 stop5h 55m
United Airlines
Deal found 4/5![United Airlines logo]()
$312
Last-minute flights from McAllen to San DiegoDiscover last-minute flight deals from McAllen to San Diego. Data last updated April 7, 2026 and is based on user searches.
Discover last-minute flight deals from McAllen to San Diego. Data last updated April 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/237:00 am
MFE
- SAN
2 stops9h 57m
United Airlines
Mon 4/273:04 pm
SAN
- MFE
1 stop5h 55m
United Airlines
Deal found 4/3![United Airlines logo]()
$302
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:23 pm
MFE
- SAN
2 stops7h 13m
Delta
Mon 4/2710:30 pm
SAN
- MFE
2 stops11h 53m
Delta
Deal found 4/3![Delta logo]()
$311
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:00 am
MFE
- SAN
1 stop6h 04m
United Airlines
Wed 4/293:04 pm
SAN
- MFE
1 stop5h 55m
United Airlines
Deal found 4/5![United Airlines logo]()
$312
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:23 pm
MFE
- SAN
2 stops7h 13m
Delta
Sun 5/39:45 pm
SAN
- MFE
2 stops12h 38m
Delta
Deal found 4/3![Delta logo]()
$291
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/303:45 pm
MFE
- SAN
1 stop8h 15m
American Airlines
Sun 5/36:15 am
SAN
- MFE
1 stop7h 10m
American Airlines
Deal found 4/2![American Airlines logo]()
$327
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:32 pm
MFE
- SAN
1 stop6h 24m
American Airlines
Sun 5/174:41 pm
SAN
- MFE
1 stop5h 18m
American Airlines
Deal found 4/4![American Airlines logo]()
$317
One-way flights from McAllen to San DiegoSearch for one-way flight options from McAllen to San Diego. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
Search for one-way flight options from McAllen to San Diego. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:32 pm
MFE
- SAN
1 stop6h 24m
American Airlines
Deal found 4/2![American Airlines logo]()
$109
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/135:17 pm
MFE
- SAN
2 stops7h 58m
Delta
Deal found 4/6![Delta logo]()
$124
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
MFE
- SAN
2 stops9h 56m
United Airlines
Deal found 4/2![United Airlines logo]()
$134
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:32 pm
MFE
- SAN
1 stop6h 24m
American Airlines
Deal found 4/6![American Airlines logo]()
$149
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1610:09 pm
MFE
- SAN
1 stop21h 43m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$166
This Delta deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/1512:56 pm
MFE
- SAN
2 stops12h 45m
Delta
Deal found 4/6![Delta logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:30 pm
MFE
- SAN
3 stops49h 29m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$192
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/215:00 am
MFE
- SAN
1 stop5h 30m
American Airlines
Deal found 4/2![American Airlines logo]()
$209
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:03 pm
MFE
- SAN
2 stops12h 35m
Delta
Deal found 4/2![Delta logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:15 pm
MFE
- SAN
3 stops40h 27m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$228
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/147:32 pm
MFE
- SAN
1 stop6h 24m
American Airlines
Deal found 4/6![American Airlines logo]()
$230
Find flight deals from McAllen to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from McAllen (MFE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $280 (Kiwi.com) |
One-way from | $109 (American Airlines) |
Popular in | December |
Cheapest in | May |
Average price | $427 |
Cheapflights Fare Finder
Customize your flight search to find flights from McAllen to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from McAllen to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Mon 6/8
12:23 pm-9:12 pm
1 stop10h 49m
San Diego
Thu 6/11
9:53 pm-11:33 am
1 stop11h 40m
$280
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Thu 4/30
5:23 pm-10:36 pm
2 stops7h 13m
San Diego
Sun 5/3
9:45 pm-12:23 pm
2 stops12h 38m
$291
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Thu 4/23
7:00 am-2:57 pm
2 stops9h 57m
San Diego
Mon 4/27
3:04 pm-10:59 pm
1 stop5h 55m
$302
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Thu 4/23
5:23 pm-10:36 pm
2 stops7h 13m
San Diego
Mon 4/27
10:30 pm-12:23 pm
2 stops11h 53m
$311
Quickest round-trip
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Tue 4/28
7:00 am-11:04 am
1 stop6h 04m
San Diego
Wed 4/29
3:04 pm-10:59 pm
1 stop5h 55m
$312
Cheapest one-way
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Wed 5/13
7:32 pm-11:56 pm
1 stop6h 24m
$109
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Wed 5/13
5:17 pm-11:15 pm
2 stops7h 58m
$124
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Sat 5/2
7:00 am-2:56 pm
2 stops9h 56m
$134
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Fri 5/15
7:32 pm-11:56 pm
1 stop6h 24m
$149
McAllenSan Diego
MFE - SAN
MFESAN
McAllen Miller Intl
Thu 4/16
10:09 pm-5:52 pm
1 stop21h 43m
$166
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from McAllen to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from McAllen to San Diego in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on McAllen-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on McAllen-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from McAllen-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on McAllen-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for McAllen-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from McAllen to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from McAllen with our price prediction graph.
MFE-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from McAllen to San Diego
Prices
More
What is the cheapest month to book a flight from McAllen to San Diego?
Currently, June is the cheapest month in which you can book a flight from McAllen to San Diego (average of $140). Flying from McAllen to San Diego in December is currently the most expensive (average of $358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from McAllen to San Diego?
What’s the top layover airport for flights from McAllen to San Diego?
Share of 1-stop round-trip flights from McAllen to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Houston (IAH) – chosen by Cheapflights users on 67% of 1-stop itineraries from McAllen to San Diego on Cheapflights.
What’s the cheapest layover airport for flights from McAllen to San Diego?
Average round-trip fare for 1-stop flights from McAllen to San Diego, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Houston (IAH) is the most affordable 1-stop option, with an average round-trip price of $454.
What’s the fastest layover option from McAllen to San Diego?
Shortest average travel time for 1-stop one-way flights from McAllen to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Phoenix (PHX) have the shortest average one-way travel time for 1-stop routes: 4h 47m.
Which airport typically offers the quickest layover for flights from McAllen to San Diego?
Average layover duration for 1-stop one-way flights from McAllen to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Phoenix (PHX) offer the fastest connection on this route, with an average layover time of 1h 01m.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated April 7, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from McAllen to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.1
Food
6.6
Overall
7.4
Comfort
7.3
Crew
8.1
Boarding
7.7
Reviews
1 / 20
10.0
ExcellentSunderesh,Dec 2025
AUS - EWR
Entertainment
7.1
Food
6.6
Overall
7.4
Comfort
7.3
Crew
8.1
Boarding
7.7
Reviews
1 / 20
10.0
ExcellentSunderesh,Dec 2025
AUS - EWR
Entertainment
7.1
Food
6.6
Overall
7.4
Comfort
7.3
Crew
8.1
Boarding
7.7
Reviews
1 / 20
10.0
ExcellentSunderesh,Dec 2025
AUS - EWR
Related info for your journey
Find useful and relevant information for your journey from McAllen to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove
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McAllen and San Diego flights
Browse other McAllen and San Diego flight options. Last updated on April 7, 2026.
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Popular flight searches
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Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 7, 2026.
Top 2 airlines flying from McAllen to San Diego
Discover the top 2 airlines that operate flights from McAllen to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$216 | Average$400 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$217 | Average$358 | FlexibilityNo cancel fee | On-time69% |