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$1,146+ Cheap flights from Mayagüez (MAZ) to San Diego (SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAZ — SAN
Aug 5 — Aug 121
Wed 8/5
Wed 8/12
1 adult, Economy
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Cheap flight deals from Mayagüez to San Diego

Cheapest flights from Mayagüez to San Diego
Explore the most affordable flight options available from Mayagüez to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 6, 2026.

This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/21:19 pm
MAZ
-
SAN
3 stops38h 12m
United Airlines
Tue 10/69:20 pm
SAN
-
MAZ
2 stops15h 51m
United Airlines
Deal found 7/1$1,146
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/181:19 pm
MAZ
-
SAN
2 stops28h 44m
United Airlines
Wed 7/229:05 pm
SAN
-
MAZ
2 stops16h 06m
United Airlines
Deal found 7/3$1,877

Find flight deals from Mayagüez to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Mayagüez (MAZ) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 6, 2026.

Round-trip from

$1,146
(United Airlines)
From Mayagüez Eugenio M De Hostos to San Diego
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mayagüez to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 6, 2026.
Use the filters below to find and compare flights from Mayagüez to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Fri 10/2

1:19 pm-12:31 am

3 stops38h 12m

San Diego

Tue 10/6

9:20 pm-4:11 pm

2 stops15h 51m

$1,146
Quickest round-trip

MayagüezSan Diego

MAZ - SAN

MAZSAN

Mayagüez Eugenio M De Hostos

Sat 7/18

1:19 pm-4:24 pm

3 stops30h 05m

San Diego

Wed 7/22

10:30 pm-4:11 pm

2 stops14h 41m

$1,877

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Sorted by cheapest first

Best time to book a flight from Mayagüez to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mayagüez with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Mayagüez to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Mayagüez to San Diego?

    A quick flight from Mayagüez to San Diego can take about 38h 12m. United Airlines provides one of the quickest options available for as low as $1,146. Airlines will cover a distance of 3243 mi.

  • Can I find deals for flights from Mayagüez to San Diego that include hotel bookings?

    Yes. In addition to deals on Mayagüez to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mayagüez to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mayagüez to San Diego.

  • Can I find deals for business class flights from Mayagüez to San Diego?

    Yes. Cheapflights offers flight deals from Mayagüez to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
National City
Chula Vista
Poway
La Mesa
Coronado
Santee
San Ysidro
Julian
Lemon Grove

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