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$640+ Cheap flights from Lyon (LYS) to San Diego (SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/2. Fares are subject to change and may not be available on all flights or dates of travel.
LYS — SAN
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Lyon to San Diego

Cheapest flights from Lyon to San Diego
Explore the most affordable flight options available from Lyon to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:25 am
LYS
-
SAN
2 stops23h 28m
United Airlines
Wed 9/3011:20 am
SAN
-
LYS
2 stops17h 10m
United Airlines
Deal found 1/27$640
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:15 pm
LYS
-
SAN
2 stops19h 01m
United Airlines
Sat 9/198:10 am
SAN
-
LYS
1 stop18h 30m
United Airlines
Deal found 1/27$643
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:15 pm
LYS
-
SAN
2 stops19h 01m
United Airlines
Fri 9/255:15 pm
SAN
-
LYS
1 stop14h 50m
United Airlines
Deal found 1/27$644
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/32:15 pm
LYS
-
SAN
2 stops19h 01m
United Airlines
Mon 9/2111:00 am
SAN
-
LYS
2 stops17h 50m
United Airlines
Deal found 1/27$645
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/29:25 am
LYS
-
SAN
1 stop15h 00m
Lufthansa
Wed 9/307:00 am
SAN
-
LYS
2 stops20h 20m
Lufthansa
Deal found 1/27$648
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:25 am
LYS
-
SAN
1 stop15h 00m
United Airlines
Tue 9/228:35 am
SAN
-
LYS
2 stops18h 05m
United Airlines
Deal found 1/27$651
This Expedia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/1410:50 am
LYS
-
SAN
2 stops21h 24m
Lufthansa
Sat 3/211:53 pm
SAN
-
LYS
2 stops20h 22m
Lufthansa
Deal found 1/27$652
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/49:25 am
LYS
-
SAN
1 stop15h 00m
United Airlines
Sat 9/197:00 am
SAN
-
LYS
2 stops21h 20m
United Airlines
Deal found 1/27$653
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:55 am
LYS
-
SAN
1 stop15h 50m
United Airlines
Sun 3/87:00 am
SAN
-
LYS
2 stops20h 10m
United Airlines
Deal found 1/26$655
This American Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/256:10 am
LYS
-
SAN
2 stops23h 27m
American Airlines
Wed 3/41:32 pm
SAN
-
LYS
2 stops15h 38m
American Airlines
Deal found 1/28$657
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:10 am
LYS
-
SAN
2 stops25h 20m
American Airlines
Sun 3/810:35 pm
SAN
-
LYS
2 stops35h 00m
American Airlines
Deal found 1/27$658
This Iberia deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Iberia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:10 am
LYS
-
SAN
2 stops23h 10m
Multiple Airlines
Thu 3/56:00 pm
SAN
-
LYS
1 stop17h 20m
Multiple Airlines
Deal found 1/27$660

Find flight deals from Lyon to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Lyon (LYS) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$643
(United Airlines)

Popular in

July

Cheapest in

November

Average price

$707
Provider with most accurate pricing for Lyon-Saint Exupéry-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lyon-Saint Exupéry-San Diego flights.
Search Deals
From Lyon-Saint Exupéry to San Diego
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($61 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lyon to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Lyon to San Diego that are best for you.

Fly from

Lyon

Fly to

San Diego

Route

Depart

Return

Price

LyonSan Diego

LYS - SAN

LYSSAN

Lyon-Saint Exupéry

Fri 3/13

10:55 am-8:53 pm

2 stops17h 58m

San Diego

Fri 3/20

5:50 pm-10:05 am

2 stops32h 15m

$643

LyonSan Diego

LYS - SAN

LYSSAN

Lyon-Saint Exupéry

Wed 3/4

10:45 am-12:29 am

2 stops22h 44m

San Diego

Sun 3/8

10:30 pm-10:05 am

2 stops27h 35m

$643

LyonSan Diego

LYS - SAN

LYSSAN

Lyon-Saint Exupéry

Sat 2/14

10:50 am-12:29 am

2 stops22h 39m

San Diego

Sat 3/14

7:55 am-1:50 pm

2 stops21h 55m

$645

LyonSan Diego

LYS - SAN

LYSSAN

Lyon-Saint Exupéry

Thu 2/26

6:10 am-8:20 pm

2 stops23h 10m

San Diego

Thu 3/5

6:00 pm-8:20 pm

1 stop17h 20m

$660

LyonSan Diego

LYS - SAN

LYSSAN

Lyon-Saint Exupéry

Wed 3/4

6:10 am-10:34 pm

2 stops25h 24m

San Diego

Sun 3/8

3:19 pm-1:15 pm

2 stops37h 56m

$660

LyonSan Diego

LYS - SAN

LYSSAN

Lyon-Saint Exupéry

Wed 3/4

7:00 pm-9:44 pm

2 stops35h 44m

San Diego

Sun 3/8

7:00 pm-1:15 pm

1 stop34h 15m

$673

LyonSan Diego

LYS - SAN

LYSSAN

Lyon-Saint Exupéry

Thu 2/26

6:40 am-6:45 pm

2 stops21h 05m

San Diego

Thu 3/5

7:20 am-11:05 am

2 stops18h 45m

$711

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

  • Most accurate provider: When it comes to deals on Lyon-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Lyon-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Lyon-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Lyon-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Lyon-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Lyon to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Lyon with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lyon to San Diego

How far ahead should I book a flight from Lyon to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Lyon to San Diego. Price data was last updated on January 23, 2026.

The best time to book flights from Lyon to San Diego is 46 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Lyon to San Diego?

Currently, June is the cheapest month in which you can book a flight from Lyon to San Diego (average of $583). Flying from Lyon to San Diego in July is currently the most expensive (average of $915). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Lyon to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Lyon to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Lyon to San Diego?

    United Airlines can get you from Lyon to San Diego in just under 17h 58m. Your travel time can differ by up to . The distance between Lyon and San Diego is about 5923 mi.

  • Can I find deals for flights from Lyon to San Diego that include hotel bookings?

    Yes. In addition to deals on Lyon to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lyon to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lyon to San Diego.

  • Can I find deals for business class flights from Lyon to San Diego?

    Yes. Cheapflights offers flight deals from Lyon to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lyon to San Diego?

    Currently, June is the cheapest month in which you can book a flight from Lyon to San Diego (average of $583). Flying from Lyon to San Diego in July is currently the most expensive (average of $915). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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