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$258+ Cheap flights from Key West to San Diego (EYW - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/11. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — SAN
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
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Cheap flight deals from Key West to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Key West (EYW) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$309
(American Airlines)

One-way from

$258
(United Airlines)
From Key West to San Diego
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One-way flight from Key West to San Diego
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Find flight deals from Key West to San Diego

Cheapest flights from Key West to San Diego
Explore the most affordable flight options available from Key West to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/51:55 pmEYW - SAN
1 stop8h 48mAmerican Airlines
Wed 11/126:46 amSAN - EYW
1 stop8h 05mAmerican Airlines
Deal found 7/29$309
This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/64:00 pmEYW - SAN
2 stops21h 21mUnited Airlines
Tue 11/1112:07 pmSAN - EYW
3 stops23h 02mUnited Airlines
Deal found 7/29$682
This Booking.com deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/68:55 amEYW - SAN
3 stops54h 32mBreeze Airways
Tue 11/111:21 pmSAN - EYW
3 stops39h 54mBreeze Airways
Deal found 7/29$1,024

Cheapflights Fare Finder

 
Customize your flight search to find flights from Key West to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Key West to San Diego that are best for you.

Fly from

Key West

Fly to

San Diego

Route

Depart

Return

Price

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Wed 11/5

1:55 pm-7:43 pm

1 stop8h 48m

San Diego

Wed 11/12

6:46 am-5:51 pm

1 stop8h 05m

$309

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Thu 11/6

4:00 pm-10:21 am

2 stops21h 21m

San Diego

Tue 11/11

12:07 pm-2:09 pm

3 stops23h 02m

$682

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Thu 11/6

8:55 am-12:27 pm

3 stops54h 32m

San Diego

Tue 11/11

1:21 pm-8:15 am

3 stops39h 54m

$1,024

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Tue 11/11

3:05 pm-12:45 pm

3 stops24h 40m

$258

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Thu 11/27

7:00 am-1:05 pm

1 stop9h 05m

$260

Key WestSan Diego

EYW - SAN

EYWSAN

Key West

Thu 11/27

10:59 am-12:27 pm

2 stops28h 28m

$483

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Key West to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Key West with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Key West to San Diego

What is the cheapest time of day to fly from EYW to SAN?

Find hourly flight availability from Key West to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 36% on flights from Key West to San Diego by exploring options for tickets in the afternoon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 29, 2025.
Read reviews from past customers who have flown Delta, Breeze Airways, and United Airlines from Key West to San Diego. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,979 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Breeze Airways
8.0
Very good
190 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,979 reviews

Comfort

7.9

Boarding

8.2

Overall

8.0

Entertainment

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Key West to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Key West to San Diego round-trip?

    According to our current data, American Airlines ($309), United Airlines ($682), and Breeze Airways ($1,024) offers the cheapest pricing from Key West to San Diego.

  • What are the cheapest airlines to fly from Key West to San Diego one-way?

    The cheapest airlines for a one-way flight from Key West to San Diego are United Airlines ($258), Delta ($260), and Breeze Airways ($483).

  • Can I find deals for flights from Key West to San Diego that include hotel bookings?

    Yes. In addition to deals on Key West to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Key West to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Key West to San Diego.

  • Can I find deals for business class flights from Key West to San Diego?

    Yes. Cheapflights offers flight deals from Key West to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Key West to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Key West to San Diego (average of $286). Flying from Key West to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
Poway
National City
Lemon Grove
Imperial Beach
La Mesa
Alpine
Santee

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Top airline flying from Key West to San Diego

Discover the top airline that operate flights from Key West to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$299Average$468FlexibilityNo cancel feeOn-time71%

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