$312+ Cheap flights from Guayaquil (GYE) to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SAN
Jun 2 — Jun 91
Round-trip
1 adult, Economy
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Find cheap flights from Guayaquil to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to San Diego
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Best
Last-minute
One-way
Cheapest flights from Guayaquil to San DiegoExplore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
Explore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 3, 2026.
This eDestinos deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:00 pm
GYE
- SAN
1 stop25h 35m
Multiple Airlines
Tue 10/137:00 am
SAN
- GYE
1 stop22h 45m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$538
This Avianca deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/14:05 pm
GYE
- SAN
1 stop20h 32m
Multiple Airlines
Fri 11/610:47 am
SAN
- GYE
1 stop20h 58m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$557
This Avianca deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:40 pm
GYE
- SAN
1 stop15h 57m
Multiple Airlines
Thu 11/510:47 am
SAN
- GYE
1 stop20h 58m
Multiple Airlines
Deal found 5/1![Multiple Airlines logo]()
$566
This Avianca deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/248:00 pm
GYE
- SAN
1 stop20h 25m
Multiple Airlines
Thu 9/32:17 pm
SAN
- GYE
1 stop15h 28m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$602
This FlightHub deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:05 pm
GYE
- SAN
1 stop22h 43m
Multiple Airlines
Sat 5/167:00 am
SAN
- GYE
1 stop22h 45m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$604
This eDestinos deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:40 pm
GYE
- SAN
1 stop26h 19m
Multiple Airlines
Mon 11/309:56 pm
SAN
- GYE
1 stop33h 49m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$612
Best flights from Guayaquil to San DiegoDiscover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
Discover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 3, 2026.
This eDestinos deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/233:30 am
GYE
- SAN
2 stops19h 03m
Multiple Airlines
Thu 9/32:17 pm
SAN
- GYE
1 stop15h 28m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$624
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:28 am
GYE
- SAN
2 stops28h 23m
United Airlines
Wed 5/273:10 pm
SAN
- GYE
2 stops27h 42m
United Airlines
Deal found 5/1![United Airlines logo]()
$849
This Copa Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:27 am
GYE
- SAN
2 stops17h 27m
Copa Airlines
Fri 7/310:00 pm
SAN
- GYE
1 stop11h 22m
Copa Airlines
Deal found 4/29![Copa Airlines logo]()
$940
This Booking.com deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:05 am
GYE
- SAN
2 stops28h 11m
Multiple Airlines
Tue 10/137:00 am
SAN
- GYE
2 stops29h 35m
Multiple Airlines
Deal found 5/3![Multiple Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/2412:22 pm
GYE
- SAN
2 stops24h 33m
United Airlines
Thu 9/33:04 pm
SAN
- GYE
2 stops27h 48m
United Airlines
Deal found 4/30![United Airlines logo]()
$857
This Orbitz deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:00 pm
GYE
- SAN
1 stop20h 27m
Multiple Airlines
Mon 8/1010:34 am
SAN
- GYE
3 stops31h 46m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$823
Last-minute flights from Guayaquil to San DiegoDiscover last-minute flight deals from Guayaquil to San Diego. Data last updated May 3, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Diego. Data last updated May 3, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:05 pm
GYE
- SAN
1 stop22h 43m
Multiple Airlines
Sat 5/167:00 am
SAN
- GYE
1 stop22h 45m
Multiple Airlines
Deal found 4/30![Multiple Airlines logo]()
$604
This American Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:31 pm
GYE
- SAN
2 stops19h 44m
American Airlines
Sat 5/1610:05 pm
SAN
- GYE
1 stop21h 07m
American Airlines
Deal found 4/30![American Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:22 pm
GYE
- SAN
2 stops27h 28m
United Airlines
Sat 5/166:15 am
SAN
- GYE
2 stops15h 21m
United Airlines
Deal found 4/30![United Airlines logo]()
$808
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/248:28 am
GYE
- SAN
2 stops28h 23m
United Airlines
Wed 5/273:10 pm
SAN
- GYE
2 stops27h 42m
United Airlines
Deal found 5/1![United Airlines logo]()
$849
One-way flights from Guayaquil to San DiegoSearch for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
Search for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated May 3, 2026.
This eDestinos deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:00 pm
GYE
- SAN
1 stop20h 38m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/173:30 am
GYE
- SAN
3 stops40h 29m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:05 am
GYE
- SAN
3 stops39h 39m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$368
This United Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/192:43 pm
GYE
- SAN
2 stops29h 10m
United Airlines
Deal found 4/28![United Airlines logo]()
$377
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2210:05 am
GYE
- SAN
3 stops48h 37m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$380
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/183:30 am
GYE
- SAN
3 stops41h 09m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$385
This eDestinos deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/154:05 pm
GYE
- SAN
1 stop24h 33m
Multiple Airlines
Deal found 5/2![Multiple Airlines logo]()
$395
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/223:30 am
GYE
- SAN
3 stops31h 12m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$407
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:59 pm
GYE
- SAN
2 stops38h 10m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$408
Find flight deals from Guayaquil to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 3, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $538 (eDestinos) |
One-way from | $312 (eDestinos) |
Popular in | May |
Cheapest in | October |
Average price | $857 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
Use the filters below to find and compare flights from Guayaquil to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Sun 8/23
3:30 am-8:33 pm
2 stops19h 03m
San Diego
Thu 9/3
2:17 pm-7:45 am
1 stop15h 28m
$624
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Thu 10/1
10:05 am-12:16 pm
2 stops28h 11m
San Diego
Tue 10/13
7:00 am-2:35 pm
2 stops29h 35m
$674
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Thu 8/6
8:00 pm-2:27 pm
1 stop20h 27m
San Diego
Mon 8/10
10:34 am-8:20 pm
3 stops31h 46m
$823
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Sun 5/24
8:28 am-10:51 am
2 stops28h 23m
San Diego
Wed 5/27
3:10 pm-8:52 pm
2 stops27h 42m
$849
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 8/24
12:22 pm-10:55 am
2 stops24h 33m
San Diego
Thu 9/3
3:04 pm-8:52 pm
2 stops27h 48m
$857
Quickest round-trip
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 6/15
8:27 am-11:54 pm
2 stops17h 27m
San Diego
Fri 7/3
10:00 pm-11:22 am
1 stop11h 22m
$940
Cheapest one-way
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Mon 6/1
8:00 pm-2:38 pm
1 stop20h 38m
$312
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Thu 5/21
2:43 pm-7:50 pm
2 stops31h 07m
$377
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Sun 5/24
12:22 pm-5:41 pm
2 stops31h 19m
$377
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 5/22
2:43 pm-9:24 pm
2 stops32h 41m
$377
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Diego in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Guayaquil with our price prediction graph.
GYE-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Guayaquil to San Diego
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated May 3, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Guayaquil to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Comfort
7.4
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Comfort
7.4
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Food
6.8
Boarding
7.8
Entertainment
6.8
Crew
8.1
Comfort
7.4
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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Coronado
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Julian
Lemon Grove
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Guayaquil and San Diego flights
Browse other Guayaquil and San Diego flight options. Last updated on May 3, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on May 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 3, 2026.
Top 2 airlines flying from Guayaquil to San Diego
Discover the top 2 airlines that operate flights from Guayaquil to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$280 | Average$567 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$337 | Average$496 | FlexibilityNo cancel fee | On-time69% |