$248+ Cheap flights from Guayaquil (GYE) to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/3. Fares are subject to change and may not be available on all flights or dates of travel.
GYE — SAN
Apr 21 — Apr 281
Round-trip
1 adult, Economy
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Find cheap flights from Guayaquil to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Guayaquil to San Diego
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Cheapest flights from Guayaquil to San DiegoExplore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
Explore the most affordable flight options available from Guayaquil to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:31 pm
GYE
- SAN
2 stops20h 07m
American Airlines
Sat 5/1612:53 pm
SAN
- GYE
1 stop22h 38m
American Airlines
Deal found 3/16![American Airlines logo]()
$561
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:59 pm
GYE
- SAN
2 stops25h 45m
Multiple Airlines
Mon 4/139:18 pm
SAN
- GYE
1 stop12h 04m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$594
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:59 pm
GYE
- SAN
2 stops18h 57m
Multiple Airlines
Tue 4/213:48 pm
SAN
- GYE
1 stop29h 16m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$614
This FlightHub deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:25 pm
GYE
- SAN
2 stops27h 37m
JetBlue
Sat 5/163:20 pm
SAN
- GYE
1 stop17h 38m
JetBlue
Deal found 3/20![JetBlue logo]()
$626
This eDestinos deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/14:05 pm
GYE
- SAN
1 stop24h 19m
Multiple Airlines
Wed 10/77:00 am
SAN
- GYE
1 stop22h 45m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$641
This Trip.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:05 pm
GYE
- SAN
1 stop22h 49m
Multiple Airlines
Sun 10/259:56 pm
SAN
- GYE
1 stop34h 49m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$643
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:43 pm
GYE
- SAN
2 stops29h 22m
United Airlines
Tue 4/216:15 am
SAN
- GYE
2 stops15h 23m
United Airlines
Deal found 3/17![United Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:43 pm
GYE
- SAN
2 stops29h 22m
United Airlines
Fri 4/245:00 pm
SAN
- GYE
2 stops22h 31m
United Airlines
Deal found 3/16![United Airlines logo]()
$679
Best flights from Guayaquil to San DiegoDiscover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
Discover carefully curated flight deals from Guayaquil to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:31 pm
GYE
- SAN
2 stops20h 07m
American Airlines
Sat 5/1612:53 pm
SAN
- GYE
1 stop22h 38m
American Airlines
Deal found 3/16![American Airlines logo]()
$561
This FlightHub deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/812:25 pm
GYE
- SAN
2 stops24h 55m
JetBlue
Sat 5/163:20 pm
SAN
- GYE
1 stop17h 38m
JetBlue
Deal found 3/18![JetBlue logo]()
$627
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:59 pm
GYE
- SAN
1 stop13h 47m
Multiple Airlines
Tue 4/213:48 pm
SAN
- GYE
1 stop29h 16m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$631
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:43 pm
GYE
- SAN
2 stops29h 22m
United Airlines
Tue 4/216:15 am
SAN
- GYE
2 stops15h 23m
United Airlines
Deal found 3/17![United Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:43 pm
GYE
- SAN
2 stops29h 22m
United Airlines
Fri 4/245:00 pm
SAN
- GYE
2 stops22h 31m
United Airlines
Deal found 3/16![United Airlines logo]()
$679
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:28 am
GYE
- SAN
2 stops28h 35m
United Airlines
Sat 5/166:15 am
SAN
- GYE
2 stops15h 21m
United Airlines
Deal found 3/19![United Airlines logo]()
$701
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/2412:22 pm
GYE
- SAN
2 stops27h 29m
United Airlines
Tue 4/283:04 pm
SAN
- GYE
2 stops24h 27m
United Airlines
Deal found 3/18![United Airlines logo]()
$701
Last-minute flights from Guayaquil to San DiegoDiscover last-minute flight deals from Guayaquil to San Diego. Data last updated March 22, 2026 and is based on user searches.
Discover last-minute flight deals from Guayaquil to San Diego. Data last updated March 22, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:59 pm
GYE
- SAN
2 stops25h 45m
Multiple Airlines
Mon 4/139:18 pm
SAN
- GYE
1 stop12h 04m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$594
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/1411:59 pm
GYE
- SAN
2 stops18h 57m
Multiple Airlines
Tue 4/213:48 pm
SAN
- GYE
1 stop29h 16m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$614
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/142:43 pm
GYE
- SAN
2 stops29h 22m
United Airlines
Tue 4/216:15 am
SAN
- GYE
2 stops15h 23m
United Airlines
Deal found 3/17![United Airlines logo]()
$670
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/212:43 pm
GYE
- SAN
2 stops29h 22m
United Airlines
Fri 4/245:00 pm
SAN
- GYE
2 stops22h 31m
United Airlines
Deal found 3/16![United Airlines logo]()
$679
This LATAM Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure LATAM Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/214:00 pm
GYE
- SAN
1 stop22h 03m
LATAM Airlines
Fri 4/241:23 pm
SAN
- GYE
1 stop15h 32m
LATAM Airlines
Deal found 3/16![LATAM Airlines logo]()
$1,003
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:28 am
GYE
- SAN
2 stops28h 36m
United Airlines
Tue 4/283:04 pm
SAN
- GYE
2 stops30h 34m
United Airlines
Deal found 3/19![United Airlines logo]()
$701
One-way flights from Guayaquil to San DiegoSearch for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
Search for one-way flight options from Guayaquil to San Diego. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/311:59 pm
GYE
- SAN
3 stops26h 03m
Multiple Airlines
Deal found 3/16![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:59 pm
GYE
- SAN
3 stops22h 05m
Multiple Airlines
Deal found 3/18![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:59 pm
GYE
- SAN
3 stops50h 03m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$261
This Copa Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:29 am
GYE
- SAN
1 stop16h 01m
Copa Airlines
Deal found 3/18![Copa Airlines logo]()
$294
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/72:31 pm
GYE
- SAN
1 stop22h 47m
American Airlines
Deal found 3/18![American Airlines logo]()
$315
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:31 pm
GYE
- SAN
2 stops19h 44m
American Airlines
Deal found 3/18![American Airlines logo]()
$318
This Trip.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/611:59 pm
GYE
- SAN
3 stops26h 03m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/32:43 pm
GYE
- SAN
2 stops29h 10m
United Airlines
Deal found 3/18![United Airlines logo]()
$365
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/232:31 pm
GYE
- SAN
1 stop22h 47m
American Airlines
Deal found 3/20![American Airlines logo]()
$370
Find flight deals from Guayaquil to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Guayaquil (GYE) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $561 (American Airlines) |
One-way from | $248 (Kiwi.com) |
Popular in | May |
Cheapest in | October |
Average price | $580 |
Cheapflights Fare Finder
Customize your flight search to find flights from Guayaquil to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from Guayaquil to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 5/8
2:31 pm-8:38 am
2 stops20h 07m
San Diego
Sat 5/16
12:53 pm-1:31 pm
1 stop22h 38m
$561
Quickest round-trip
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 5/8
12:25 pm-11:20 am
2 stops24h 55m
San Diego
Sat 5/16
3:20 pm-10:58 am
1 stop17h 38m
$627
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Tue 4/14
11:59 pm-11:46 am
1 stop13h 47m
San Diego
Tue 4/21
3:48 pm-11:04 pm
1 stop29h 16m
$631
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Tue 4/14
2:43 pm-6:05 pm
2 stops29h 22m
San Diego
Tue 4/21
6:15 am-11:38 pm
2 stops15h 23m
$670
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Tue 4/21
2:43 pm-6:05 pm
2 stops29h 22m
San Diego
Fri 4/24
5:00 pm-5:31 pm
2 stops22h 31m
$679
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 5/8
8:28 am-11:03 am
2 stops28h 35m
San Diego
Sat 5/16
6:15 am-11:36 pm
2 stops15h 21m
$701
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 4/24
12:22 pm-1:51 pm
2 stops27h 29m
San Diego
Tue 4/28
3:04 pm-5:31 pm
2 stops24h 27m
$701
Cheapest one-way
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Wed 4/8
11:59 pm-12:02 am
3 stops50h 03m
$261
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 4/17
4:29 am-6:30 pm
1 stop16h 01m
$294
GuayaquilSan Diego
GYE - SAN
GYESAN
Guayaquil Jose Joaquin de Olmedo
Fri 4/17
2:31 pm-8:15 am
2 stops19h 44m
$318
Showing 1-10 of 18 resultsSorted by cheapest first
Compare providers for flights from Guayaquil to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Guayaquil to San Diego in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Guayaquil-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Guayaquil-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Guayaquil-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Guayaquil-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Guayaquil-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Guayaquil to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Guayaquil with our price prediction graph.
GYE-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 22, 2026.
Get a feel of what it's like to fly with Copa Airlines and United Airlines from Guayaquil to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.4
Boarding
7.8
Food
6.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Boarding
7.8
Food
6.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Comfort
7.4
Boarding
7.8
Food
6.8
Entertainment
6.8
Crew
8.1
Overall
7.5
Reviews
1 / 20
2.0
MediocreKaterine,Mar 2026
LAX - PTY
Related info for your journey
Find useful and relevant information for your journey from Guayaquil to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
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National City
Coronado
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Poway
Julian
Lemon Grove
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Guayaquil and San Diego flights
Browse other Guayaquil and San Diego flight options. Last updated on March 22, 2026.
Other flights from Guayaquil
Browse through other flights departing from Guayaquil. Flights are based on user searches made on Cheapflights and were last updated on March 22, 2026.
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Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 22, 2026.
Top 2 airlines flying from Guayaquil to San Diego
Discover the top 2 airlines that operate flights from Guayaquil to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$254 | Average$675 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$337 | Average$496 | FlexibilityNo cancel fee | On-time69% |