HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$60+ Cheap flights from Detroit Metropolitan Wayne County Airport to San Diego (DTW - SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SAN
Dec 18 — Dec 251
Thu 12/18
Thu 12/25
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to San Diego are usually found in August or July, booked 69 days in advance, depart on a Friday or Monday and return on a Thursday

Cheap flight deals from Detroit to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 18, 2025.

Most accurate provider

Justfly.com
3 stars

Most trusted provider

Justfly.com
3 stars

Round-trip from

$171
(Kiwi.com)

One-way from

$60
(Trip.com)

Popular in

March

Cheapest in

August

Average price

$519

Good round-trip deal

$519 or less

Good one-way deal

$217 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-San Diego flights.
Search Deals
From Detroit Metropolitan Wayne County to San Diego
Search Deals
One-way flight from Detroit Metropolitan Wayne County to San Diego
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($65 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to San Diego.
Search Deals
Price to beat on a one-way flight from Detroit Metropolitan Wayne County to San Diego.
Search Deals

Find flight deals from Detroit to San Diego

Cheapest flights from Detroit to San Diego
Explore the most affordable flight options available from Detroit to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 18, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1511:44 amDTW - SAN
2 stops38h 02mFrontier
Mon 1/52:10 pmSAN - DTW
1 stop28h 48mFrontier
Deal found 11/17$171
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:20 pmDTW - SAN
1 stop9h 39mMultiple Airlines
Thu 12/189:14 pmSAN - DTW
1 stop18h 13mMultiple Airlines
Deal found 11/17$174
This CheapOair deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:20 pmDTW - SAN
1 stop9h 39mFrontier
Thu 12/118:10 pmSAN - DTW
1 stop17h 09mFrontier
Deal found 11/18$176
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:20 pmDTW - SAN
1 stop9h 39mFrontier
Thu 12/181:06 pmSAN - DTW
2 stops19h 03mFrontier
Deal found 11/17$178
This Priceline deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:20 pmDTW - SAN
1 stop9h 39mFrontier
Sun 12/146:34 amSAN - DTW
1 stop6h 45mFrontier
Deal found 11/17$180
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/136:12 pmDTW - SAN
2 stops23h 11mFrontier
Wed 12/176:25 amSAN - DTW
1 stop11h 41mFrontier
Deal found 11/16$181
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amDTW - SAN
2 stops20h 51mMultiple Airlines
Thu 12/118:10 pmSAN - DTW
1 stop17h 09mMultiple Airlines
Deal found 11/16$182
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:47 pmDTW - SAN
2 stops14h 04mFrontier
Thu 12/118:10 pmSAN - DTW
1 stop17h 09mFrontier
Deal found 11/18$183
This Kiwi.com deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:20 pmDTW - SAN
1 stop9h 39mMultiple Airlines
Mon 12/156:34 amSAN - DTW
2 stops23h 40mMultiple Airlines
Deal found 11/17$186
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1810:01 pmDTW - SAN
1 stop28h 58mFrontier
Thu 12/251:06 pmSAN - DTW
2 stops19h 03mFrontier
Deal found 11/18$188
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:13 pmDTW - SAN
2 stops20h 39mFrontier
Thu 12/118:10 pmSAN - DTW
1 stop17h 09mFrontier
Deal found 11/16$189
This Kiwi.com deal was found by Cheapflights users on 11/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:47 amDTW - SAN
2 stops14h 59mMultiple Airlines
Sat 12/64:47 pmSAN - DTW
1 stop20h 32mMultiple Airlines
Deal found 11/16$191

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Diego that are best for you.

Fly from

Detroit

Fly to

San Diego

Route

Depart

Return

Price

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Fri 1/30

5:15 pm-11:09 pm

1 stop8h 54m

San Diego

Wed 2/4

5:38 pm-4:19 pm

2 stops19h 41m

$341

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Thu 1/15

5:15 pm-4:45 pm

2 stops26h 30m

San Diego

Wed 1/21

11:49 am-4:19 pm

1 stop25h 30m

$360

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Thu 1/29

5:15 pm-11:09 pm

1 stop8h 54m

San Diego

Tue 2/10

6:03 pm-4:19 pm

2 stops19h 16m

$361

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Fri 2/6

5:15 pm-11:09 pm

1 stop8h 54m

San Diego

Thu 2/12

10:06 pm-4:26 pm

2 stops15h 20m

$370

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Sun 12/14

12:56 pm-5:33 pm

1 stop7h 37m

San Diego

Sun 12/14

8:59 pm-6:15 pm

2 stops18h 16m

$384

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Sat 12/13

8:25 am-10:45 pm

1 stop17h 20m

San Diego

Wed 12/17

6:30 am-10:33 pm

1 stop13h 03m

$386

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Thu 1/1

4:50 pm-6:41 pm

Nonstop4h 51m

San Diego

Mon 1/12

11:00 am-6:30 am

1 stop16h 30m

$393

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Thu 12/4

5:41 pm-8:39 am

2 stops17h 58m

San Diego

Tue 12/9

11:41 am-4:45 pm

1 stop26h 04m

$417

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Sat 2/14

5:22 pm-2:33 pm

2 stops24h 11m

San Diego

Sat 2/21

9:49 pm-4:26 pm

2 stops15h 37m

$439

DetroitSan Diego

DTW - SAN

DTWSAN

Detroit Metropolitan Wayne County

Thu 12/4

5:41 pm-8:39 am

2 stops17h 58m

San Diego

Mon 12/8

9:37 pm-4:45 pm

2 stops16h 08m

$450

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/16

Showing 1-10 of 19 results
1
2

Compare providers for flights from Detroit to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to San Diego in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
CheapflightsfaresPrice Accuracy3 starsTrust Score*2 stars
JustAirTicketPrice Accuracy-Trust Score*1 star
CheapTicketsDealPrice Accuracy3 starsTrust Score*3 stars
Justfly.comPrice Accuracy3 starsTrust Score*3 stars
CheapOairPrice Accuracy3 starsTrust Score*3 stars
MytripPrice Accuracy3 starsTrust Score*3 stars
Trip.comPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-San Diego flights, users find the pricing of Justfly.com to be most consistent on Cheapflights vs. Justfly.com Users can find the same prices on Detroit Metropolitan Wayne County Airport-San Diego flight deals on Cheapflights vs. Justfly.com >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-San Diego flights, Cheapflights users trust Justfly.com the most. Justfly.com has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Diego

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Detroit to San Diego. Price data was last updated on November 14, 2025.

The best time to book flights from Detroit Metropolitan Wayne County Airport to San Diego is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Diego?

Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Diego (average of $104). Flying from Detroit Metropolitan Wayne County Airport to San Diego in December is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SAN?

Find hourly flight availability from Detroit to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 18, 2025.

Unlike in the evening, when flights are generally more expensive, you can save up to 38% on flights from Detroit Metropolitan Wayne County Airport to San Diego by exploring options for tickets at noon.

What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Detroit to San Diego. Price data was last updated on November 2, 2025.

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to San Diego flight should consider departing on Thursday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

The best insider tips for Detroit Metropolitan Wayne County Airport to San Diego flights

Snippets provided in this section are AI-generated based on a summarization of Cheapflights-commissioned articles. The articles are presented as-is, for general informational purposes only, and may not be up-to-date. The opinions contained in the articles are original to the author and reflect their authentic experience, which may vary significantly from the experience of others.
Cheapflights partnered with top experts to bring you the best recommendations for your Detroit Metropolitan Wayne County Airport to San Diego trip
Airports
DTW

Security lines at DTW are short, with waits rarely exceeding 10 minutes in McNamara Terminal, making it convenient for early morning flights.

Read more about DTWby Brandon Schultz
SAN

For a quick ride to downtown San Diego, consider a taxi or rideshare from SAN, but plan for potential traffic congestion.

Read more about SANby Blane Bachelor
Our travel experts
Blane Bachelor

Blane Bachelor

Expert on SAN

Blane Bachelor

Blane Bachelor

Blane Bachelor is a journalist and editor specializing in travel and aviation who writes regularly for top global outlets. Born and raised in Florida, Blane has worked and lived in four countries, including the Netherlands, where she’s currently based with her family. Her favorite way to get to know a new destination is by running or riding a bike around town – or hearing a spooky ghost story about local history. She will always choose the window seat.

Read more
Brandon Schultz

Brandon Schultz

Expert on DTW

Brandon Schultz

Brandon Schultz

Brandon Schultz is an award-winning food and travel writer based in New York City. His work has appeared in Forbes, AAA, Thrillist, Travel + Leisure, and The Daily Meal, among many others, and he is the author of 6 books, including 3 cookbooks.

Read more

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated November 18, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Detroit Metropolitan Wayne County Airport to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,248 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Delta
7.9
Good
8,003 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
American Airlines
7.2
Good
11,045 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Spirit Airlines
6.3
Okay
8,151 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Frontier
5.8
Fair
3,105 reviews
Southwest
8.0
Very good
4,248 reviews

Entertainment

7.5

Food

7.0

Overall

8.0

Crew

8.6

Comfort

8.0

Boarding

8.1

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Detroit to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to San Diego?

    Booking a flight from Detroit Metropolitan Wayne County (DTW) to San Diego (SAN) is your only option if you wish to fly from Detroit to San Diego. On a typical day, there are 6 flights from Detroit Metropolitan Wayne County to San Diego, all of which are around 4h 51m for a nonstop flight. You can also purchase a plane ticket from 6 airlines when you book a flight from Detroit Metropolitan Wayne County to San Diego.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to San Diego?

    Airlines like Alaska Airlines fly from Detroit Metropolitan Wayne County Airport to San Diego in about 8h 54m. The time it takes to get you to your destination can typically vary by up to . The distance from Detroit Metropolitan Wayne County Airport to San Diego is about 1952 mi.

  • What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to San Diego round-trip?

    Our cheapest airline available from Detroit Metropolitan Wayne County Airport to San Diego is Spirit Airlines. Our recent data shows that you can find tickets from as low as $107 on this airline. Additional options worth looking into are Frontier and American Airlines, starting at $146 and $190 round-trip. Spirit Airlines is priced at 74% lower than the current average price of a flight leaving 3 months from now.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to San Diego?

    No one likes to see their flight delayed. When booking a flight from Detroit Metropolitan Wayne County Airport to San Diego consider choosing Spirit Airlines (78%), Delta (74%) or KLM (69%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to San Diego?

    While on average a flight from Detroit Metropolitan Wayne County Airport to San Diego is generally $661, our data shows the cheapest flight currently is $216. When looking at the most popular route, (Detroit Metropolitan Wayne County - San Diego), you can expect to pay $169 for that flight.

  • Can I find deals for flights from Detroit to San Diego that include hotel bookings?

    Yes. In addition to deals on Detroit to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to San Diego.

  • Can I find deals for business class flights from Detroit to San Diego?

    Yes. Cheapflights offers flight deals from Detroit to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Diego (average of $104). Flying from Detroit Metropolitan Wayne County Airport to San Diego in December is currently the most expensive (average of $171). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Detroit to Las Vegas flights
Detroit to Los Angeles flights
Detroit to San Francisco flights
Detroit to Santa Ana flights
Detroit to Ontario flights
Detroit to Burbank flights
Detroit to Palm Springs flights
Detroit to San Jose flights
Detroit to Reno flights
Detroit to Oakland flights
Detroit to Sacramento flights
Detroit to Long Beach flights
Detroit to Santa Barbara flights
Detroit to Fresno flights
Detroit to Medford flights
Detroit to Monterey flights
Detroit to San Luis Obispo flights
Detroit to Arcata flights
Detroit to Santa Rosa flights
Detroit to Tijuana flights
Detroit to Yuma flights
Detroit to Redding flights
Detroit to Bakersfield flights
Detroit to Mammoth Lakes flights
Detroit to Merced flights

Top 6 airlines flying from Detroit to San Diego

Discover the top 6 airlines that operate flights from Detroit to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$107Average$225FlexibilityNo cancel feeOn-time65%
FrontierCheapest$146Average$226FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$190Average$217FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$293Average$416FlexibilityNo cancel feeOn-time69%
DeltaCheapest$299Average$527FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$368Average$519FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.