$96+ Cheap flights from Detroit Metropolitan Wayne County Airport to San Diego (DTW - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/21. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SAN
Oct 18 — Oct 251
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Detroit to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to San Diego are usually found in January or November, booked 52 days in advance, depart on a Saturday or Friday and return on a Friday
Cheap flight deals from Detroit to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to San DiegoExplore the most affordable flight options available from Detroit to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
Explore the most affordable flight options available from Detroit to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 18, 2026.
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:08 am -
1 stop11h 51m
Mon 10/128:34 pm -
1 stop29h 26m
Deal found 9/17![Frontier logo]()
$331
This deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:35 pm -
1 stop6h 21m
Fri 10/166:25 am -
1 stop6h 09m
Deal found 9/17![Frontier logo]()
$332
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:29 pm -
1 stop13h 20m
Thu 10/294:53 pm -
2 stops13h 55m
Deal found 9/17![Frontier logo]()
$335
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:35 pm -
2 stops19h 41m
Fri 10/162:01 pm -
2 stops16h 52m
Deal found 9/17![Frontier logo]()
$336
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:29 pm -
2 stops20h 29m
Sat 10/246:25 am -
1 stop14h 30m
Deal found 9/17![Frontier logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/107:15 am -
2 stops14h 23m
Sun 11/159:32 am -
1 stop20h 47m
Deal found 9/17![Frontier logo]()
$338
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:35 pm -
1 stop6h 21m
Thu 10/228:34 pm -
1 stop29h 26m
Deal found 9/17![Frontier logo]()
$343
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:15 am -
2 stops14h 23m
Mon 11/166:25 am -
2 stops23h 54m
Deal found 9/17![Frontier logo]()
$344
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:29 pm -
1 stop13h 20m
Thu 10/228:34 pm -
1 stop29h 26m
Deal found 9/17![Frontier logo]()
$345
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:29 pm -
1 stop13h 20m
Fri 10/236:25 am -
2 stops24h 28m
Deal found 9/17![Frontier logo]()
$347
This Cheapflightsfares deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1210:28 pm -
1 stop13h 09m
Sun 11/156:25 am -
1 stop14h 26m
Deal found 9/17![Frontier logo]()
$348
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:29 pm -
2 stops21h 20m
Fri 10/236:25 am -
2 stops24h 28m
Deal found 9/17![Frontier logo]()
$349
Best flights from Detroit to San DiegoDiscover carefully curated flight deals from Detroit to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
Discover carefully curated flight deals from Detroit to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 18, 2026.
This Alaska Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/145:45 pm -
2 stops19h 08m
Sun 11/226:15 am -
1 stop20h 26m
Deal found 9/17![Alaska Airlines logo]()
$484
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:45 am -
1 stop12h 00m
Tue 11/176:15 am -
Nonstop4h 22m
Deal found 9/17![Delta logo]()
$516
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:15 pm -
Nonstop5h 00m
Sun 12/2010:30 pm -
Nonstop4h 22m
Deal found 9/13![Delta logo]()
$559
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/174:09 pm -
Nonstop4h 46m
Sat 10/246:15 am -
Nonstop4h 27m
Deal found 9/14![Delta logo]()
$559
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:30 am -
Nonstop4h 50m
Mon 10/266:15 am -
Nonstop4h 27m
Deal found 9/17![Delta logo]()
$559
This Delta deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:20 pm -
Nonstop4h 52m
Wed 10/216:15 am -
Nonstop4h 27m
Deal found 9/13![Delta logo]()
$559
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:35 pm -
Nonstop4h 54m
Wed 11/181:22 pm -
Nonstop4h 21m
Deal found 9/17![Delta logo]()
$559
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:30 am -
Nonstop4h 50m
Wed 11/41:18 pm -
Nonstop4h 28m
Deal found 9/17![Delta logo]()
$559
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/242:30 pm -
1 stop8h 06m
Sun 11/16:15 am -
Nonstop4h 27m
Deal found 9/15![Delta logo]()
$569
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3012:35 pm -
Nonstop4h 45m
Tue 11/31:36 pm -
1 stop7h 23m
Deal found 9/17![Delta logo]()
$569
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:20 am -
1 stop7h 22m
Sat 10/316:15 am -
Nonstop4h 27m
Deal found 9/16![Delta logo]()
$569
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 am -
Nonstop4h 50m
Mon 11/99:50 pm -
1 stop9h 40m
Deal found 9/16![Delta logo]()
$569
Last-minute flights from Detroit to San DiegoDiscover last-minute flight deals from Detroit to San Diego. Data last updated September 18, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to San Diego. Data last updated September 18, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:35 pm -
1 stop6h 16m
Tue 10/136:25 am -
1 stop14h 30m
Deal found 9/17![Frontier logo]()
$352
This Booking.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:08 am -
1 stop11h 51m
Mon 10/128:34 pm -
1 stop29h 26m
Deal found 9/17![Frontier logo]()
$331
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/77:15 am -
1 stop12h 44m
Tue 10/136:25 am -
1 stop14h 30m
Deal found 9/17![Frontier logo]()
$354
This deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/118:35 pm -
1 stop6h 21m
Fri 10/166:25 am -
1 stop6h 09m
Deal found 9/17![Frontier logo]()
$332
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:35 pm -
2 stops19h 41m
Fri 10/162:01 pm -
2 stops16h 52m
Deal found 9/17![Frontier logo]()
$336
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:03 pm -
3 stops25h 13m
Sat 10/314:53 pm -
2 stops15h 16m
Deal found 9/17![Multiple Airlines logo]()
$350
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:35 pm -
1 stop6h 21m
Thu 10/228:34 pm -
1 stop29h 26m
Deal found 9/17![Frontier logo]()
$343
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1510:29 pm -
1 stop13h 20m
Fri 10/236:25 am -
2 stops24h 28m
Deal found 9/17![Frontier logo]()
$347
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1610:29 pm -
2 stops21h 20m
Fri 10/236:25 am -
2 stops24h 28m
Deal found 9/17![Frontier logo]()
$349
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:29 pm -
1 stop13h 20m
Thu 10/294:53 pm -
2 stops13h 55m
Deal found 9/17![Frontier logo]()
$335
This Expedia deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:29 pm -
1 stop13h 20m
Thu 10/228:34 pm -
1 stop29h 26m
Deal found 9/17![Frontier logo]()
$345
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:29 pm -
2 stops20h 29m
Sat 10/246:25 am -
1 stop14h 30m
Deal found 9/17![Frontier logo]()
$337
One-way flights from Detroit to San DiegoSearch for one-way flight options from Detroit to San Diego. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
Search for one-way flight options from Detroit to San Diego. Find affordable one-way fares based on user searches. Data last updated September 18, 2026.
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:35 pm -
1 stop6h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$96
This Cheapflightsfares deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:00 am -
1 stop11h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$99
This Super.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/67:08 am -
1 stop11h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![Frontier logo]()
$100
This Super.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/248:35 pm -
1 stop6h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Frontier logo]()
$101
This Super.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:00 am -
1 stop19h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Frontier logo]()
$102
This Priceline deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:35 pm -
1 stop6h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Frontier logo]()
$103
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop11h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Frontier logo]()
$104
This Super.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/278:35 pm -
1 stop22h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/13![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:35 pm -
1 stop6h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:00 am -
1 stop11h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Frontier logo]()
$110
Find flight deals from Detroit to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 18, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $332 |
One-way from | $96 (Priceline) |
Popular in | June |
Cheapest in | January |
Average price | $554 |
Good round-trip deal | $546 or less |
Good one-way deal | $468 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Mon 10/5
7:17 pm-9:05 am
2 stops16h 48m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$339
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Tue 9/22
7:01 am-5:10 pm
2 stops13h 09m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$403
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Fri 10/2
5:39 pm-8:22 am
2 stops17h 43m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$406
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Sun 12/6
8:25 am-10:27 am
Nonstop5h 02m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Sun 11/8
8:20 pm-10:12 pm
Nonstop4h 52m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Sun 11/15
4:35 pm-6:29 pm
Nonstop4h 54m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
Quickest round-trip
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Sat 10/17
8:30 am-10:20 am
Nonstop4h 50m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Mon 12/7
4:30 pm-6:24 pm
Nonstop4h 54m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Fri 11/20
8:12 pm-10:10 pm
Nonstop4h 58m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
DetroitSan Diego
DTW Detroit Metropolitan Wayne County - SAN San Diego
DTWSAN
Detroit Metropolitan Wayne County
Thu 10/22
8:30 am-10:20 am
Nonstop4h 50m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$410
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Detroit to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to San Diego in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy- | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy2 stars | Trust Score*1 star | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Detroit with our price prediction graph.
DTW-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Diego
Prices
Airlines
More
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Diego?
The best time to book flights from Detroit Metropolitan Wayne County Airport to San Diego is 51 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Diego?
Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Diego (average of $326). Flying from Detroit Metropolitan Wayne County Airport to San Diego in June is currently the most expensive (average of $581). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to SAN?
Find hourly flight availability from Detroit to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 18, 2026.
When flying from Detroit Metropolitan Wayne County Airport to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to San Diego?
Share of 1-stop round-trip flights from Detroit Metropolitan Wayne County Airport to San Diego chosen by Cheapflights users in the past 12 months, using the same layover each way.
Dallas (DFW) – chosen by Cheapflights users on 70% of 1-stop itineraries from Detroit Metropolitan Wayne County Airport to San Diego on Cheapflights.
What’s the cheapest layover airport for flights from Detroit Metropolitan Wayne County Airport to San Diego?
Average round-trip fare for 1-stop flights from Detroit Metropolitan Wayne County Airport to San Diego, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $143.
What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Diego?
Shortest average travel time for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to San Diego, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Dallas (DFW) have the shortest average one-way travel time for 1-stop routes: 8h 21m.
Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to San Diego?
Average layover duration for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to San Diego, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Dallas (DFW) offer the fastest connection on this route, with an average layover time of 2h 32m.
The best insider tips for Detroit Metropolitan Wayne County Airport to San Diego flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Detroit Metropolitan Wayne County Airport to San Diego trip
Our travel experts
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated September 18, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Detroit Metropolitan Wayne County Airport to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Overall
8.0
Crew
8.6
Food
7.0
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Detroit to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Coronado
San Ysidro
Poway
La Mesa
Santee
Julian
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Detroit
Popular flights
San Diego flight routes
Alternative routes for Detroit to San Diego
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Detroit to San Diego by cabin class
Find flights from Detroit to San Diego, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Detroit and San Diego flights
Browse other Detroit and San Diego flight options. Last updated on September 18, 2026.
Other flights from Detroit
Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 18, 2026.
Top 6 airlines flying from Detroit to San Diego
Discover the top 6 airlines that operate flights from Detroit to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$146 | Average$268 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$151 | Average$428 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$233 | Average$468 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$284 | Average$488 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$293 | Average$538 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$499 | Average$613 | FlexibilityNo cancel fee | On-timeN/A |