San Diego

Cheap flights from the Cayman Islands to San Diego (SAN)

GCM — SAN
Feb 10 — Feb 171
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Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated January 11, 2026.
See what other customers who have flown with American Airlines from the Cayman Islands to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Boarding

7.5

Overall

7.2

Entertainment

6.9

Comfort

7.2

Food

6.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Boarding

7.5

Overall

7.2

Entertainment

6.9

Comfort

7.2

Food

6.4

Crew

8.0

Reviews

1 / 20
4.0
Okay

Susie,Jan 2026

TPA - CLT

I was sitting at the back of the plane and the flight attendants were so loud, talking to each other and laughing! I thought they were having a party back there.

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to San Diego from Cayman Islands?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Cayman Islands. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • Can I find deals for flights from Cayman Islands to San Diego that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to San Diego.

  • Can I find deals for business class flights from Cayman Islands to San Diego?

    Yes. Cheapflights offers flight deals from Cayman Islands to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Alternative routes for Cayman Islands to San Diego

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Top airline flying from Cayman Islands to San Diego

Discover the top airline that operate flights from Cayman Islands to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$645FlexibilityNo cancel feeOn-time71%

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