HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
San Diego

$580+ Cheap flights from the Cayman Islands to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
Aug 6 — Aug 131
Wed 8/6
Wed 8/13
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Cayman Islands to San Diego with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Cayman Islands to San Diego

One-way flights from Cayman Islands to San Diego
Search for one-way flight options from Cayman Islands to San Diego. Find affordable one-way fares based on user searches. Data last updated August 1, 2025.

This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/155:30 pmGCM - SAN
2 stops19h 09mUnited Airlines
Deal found 7/31$580
This American Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/211:00 pmGCM - SAN
2 stops13h 56mAmerican Airlines
Deal found 7/31$847
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:25 amGCM - SAN
3 stops31h 55mMultiple Airlines
Deal found 7/31$1,019
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/212:02 pmGCM - SAN
1 stop10h 33mDelta
Deal found 7/31$1,493

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cayman Islands to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2025.
Use the filters below to find and compare flights from the Cayman Islands to San Diego that are best for you.

Fly from

Cayman Islands

Fly to

San Diego

Route

Depart

Return

Price

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Sat 11/15

5:30 pm-9:39 am

2 stops19h 09m

$580

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 11/21

1:00 pm-11:56 pm

2 stops13h 56m

$847

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 11/21

11:25 am-4:20 pm

3 stops31h 55m

$1,019

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 11/21

2:02 pm-9:35 pm

1 stop10h 33m

$1,493

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Best time to book a flight from Cayman Islands to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Cayman Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Cayman Islands to San Diego
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated August 1, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from the Cayman Islands to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
8.0
Very good
7,983 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,904 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,983 reviews

Crew

8.5

Boarding

8.2

Entertainment

7.9

Food

7.3

Comfort

7.9

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Cayman Islands?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Cayman Islands. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • What are the cheapest airlines to fly from Cayman Islands to San Diego one-way?

    The cheapest airlines for a one-way flight from Cayman Islands to San Diego are United Airlines ($580), American Airlines ($847), and Delta ($1,493).

  • Can I find deals for flights from Cayman Islands to San Diego that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to San Diego.

  • Can I find deals for business class flights from Cayman Islands to San Diego?

    Yes. Cheapflights offers flight deals from Cayman Islands to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cayman Islands to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Cayman Islands to San Diego (average of $286). Flying from Cayman Islands to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
Poway
National City
Lemon Grove
Imperial Beach
La Mesa
Alpine

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Cayman Islands to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
Luis Munoz Marin Intl to Las Vegas flights
Luis Munoz Marin Intl to Los Angeles flights
Santo Domingo to Las Vegas flights
Luis Munoz Marin Intl to San Diego flights
Luis Munoz Marin Intl to San Francisco flights
Luis Munoz Marin Intl to San Jose flights
Kingston to Las Vegas flights
Luis Munoz Marin Intl to Ontario flights
Nassau to Las Vegas flights
Nassau to Los Angeles flights
Luis Munoz Marin Intl to Sacramento flights
Santo Domingo to Los Angeles flights
Simpson Bay to Las Vegas flights
George Town to Los Angeles flights
Luis Munoz Marin Intl to Burbank flights
Luis Munoz Marin Intl to Santa Ana flights
Bridgetown to Los Angeles flights
Santiago de los Caballeros to Las Vegas flights
Port of Spain to Los Angeles flights
Port of Spain to San Francisco flights
Simpson Bay to Los Angeles flights
Montego Bay to Las Vegas flights
Santo Domingo to San Francisco flights
Kingston to Los Angeles flights
Montego Bay to Los Angeles flights
Port of Spain to Las Vegas flights
Oranjestad to Los Angeles flights
Saint Thomas Island to San Diego flights
Aguadilla to Los Angeles flights
Fort-de-France to Los Angeles flights
Montego Bay to San Francisco flights
Oranjestad to Las Vegas flights
Punta Cana to Las Vegas flights
Saint Thomas Island to Ontario flights
Luis Munoz Marin Intl to Reno flights
Santo Domingo to San Diego flights
Bridgetown to San Diego flights
Kingston to San Francisco flights
Saint Thomas Island to San Francisco flights
Saint Thomas Island to Los Angeles flights
Montego Bay to San Diego flights
Nassau to San Francisco flights
Punta Cana to Los Angeles flights
Santiago de los Caballeros to Los Angeles flights
Santiago de los Caballeros to San Francisco flights
Bridgetown to Las Vegas flights
Saint Thomas Island to Las Vegas flights

Top airline flying from Cayman Islands to San Diego

Discover the top airline that operate flights from Cayman Islands to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$495Average$650FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.