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$284+ Cheap flights from the Cayman Islands to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
Dec 3 — Dec 101
Wed 12/3
Wed 12/10
1 adult, Economy
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Cheap flight deals from Cayman Islands to San Diego

Keep the following information in mind while searching for Cayman Islands to San Diego flight deals. Data was last updated November 3, 2025.

Round-trip from

$487
(United Airlines)

One-way from

$284
(Kiwi.com)
From Cayman Islands to San Diego
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One-way flight from Cayman Islands to San Diego
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Find flight deals from Cayman Islands to San Diego

Cheapest flights from Cayman Islands to San Diego
Explore the most affordable flight options available from Cayman Islands to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:45 pmGCM - SAN
2 stops24h 16mUnited Airlines
Wed 12/244:45 pmSAN - GCM
1 stop18h 00mUnited Airlines
Deal found 11/2$487

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cayman Islands to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from the Cayman Islands to San Diego that are best for you.

Fly from

Cayman Islands

Fly to

San Diego

Route

Depart

Return

Price

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Wed 12/17

5:45 pm-10:43 am

2 stops19h 58m

San Diego

Wed 12/24

5:40 pm-4:00 pm

2 stops19h 20m

$487

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Tue 3/10

12:40 pm-8:18 pm

1 stop9h 38m

San Diego

Wed 3/11

11:00 pm-1:20 pm

1 stop12h 20m

$606

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 12/4

2:40 pm-11:59 pm

3 stops36h 19m

$284

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 12/4

5:45 pm-10:21 am

2 stops19h 36m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Thu 12/4

1:50 pm-9:18 pm

1 stop10h 28m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 1/23

2:50 pm-10:27 am

2 stops22h 37m

$874

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

Fri 1/23

7:00 am-4:40 pm

3 stops36h 40m

$963

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Best time to book a flight from Cayman Islands to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Cayman Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Cayman Islands to San Diego
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated November 3, 2025.
See what other customers who have flown with American Airlines from the Cayman Islands to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
11,037 reviews

Overall

7.2

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.
American Airlines
7.2
Good
11,037 reviews
American Airlines
7.2
Good
11,037 reviews

Overall

7.2

Boarding

7.5

Comfort

7.2

Crew

8.0

Entertainment

6.9

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Cayman Islands?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Cayman Islands. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How long is the flight from Cayman Islands to San Diego?

    Airlines like United Airlines and American Airlines fly from Cayman Islands to San Diego in about 9h 38m. The time it takes to get you to your destination can typically vary by up to 10h 20m. There are 2395 mi between Cayman Islands and San Diego. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Cayman Islands to San Diego that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to San Diego.

  • Can I find deals for business class flights from Cayman Islands to San Diego?

    Yes. Cheapflights offers flight deals from Cayman Islands to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Top airline flying from Cayman Islands to San Diego

Discover the top airline that operate flights from Cayman Islands to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$485Average$650FlexibilityNo cancel feeOn-time71%

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