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$296+ Cheap flights from the Cayman Islands to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/14. Fares are subject to change and may not be available on all flights or dates of travel.
GCM — SAN
oct. 16 — oct. 231
jue. 10/16
jue. 10/23
1 adult, Economy
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Cheap flight deals from Cayman Islands to San Diego

Keep the following information in mind while searching for Cayman Islands to San Diego flight deals. Data was last updated septiembre 16, 2025.

Round-trip from

$496
(United Airlines)

One-way from

$296
(United Airlines)
From Cayman Islands to San Diego
Search Deals
One-way flight from Cayman Islands to San Diego
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Find flight deals from Cayman Islands to San Diego

Cheapest flights from Cayman Islands to San Diego
Explore the most affordable flight options available from Cayman Islands to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 16, 2025.

This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2212:25 pmGCM - SAN
1 stop24h 31mAmerican Airlines
dom. 10/2610:45 pmSAN - GCM
1 stop10h 25mAmerican Airlines
Deal found 9/13$496
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/2912:25 pmGCM - SAN
1 stop9h 25mAmerican Airlines
lun. 10/610:45 pmSAN - GCM
1 stop10h 25mAmerican Airlines
Deal found 9/15$641
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/2612:25 pmGCM - SAN
1 stop23h 55mAmerican Airlines
lun. 9/293:01 pmSAN - GCM
2 stops18h 09mAmerican Airlines
Deal found 9/14$645
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 10/2211:30 amGCM - SAN
3 stops34h 05mMultiple Airlines
dom. 10/268:10 amSAN - GCM
2 stops26h 34mMultiple Airlines
Deal found 9/13$1,087
This FlightHub deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 9/2611:25 amGCM - SAN
1 stop24h 43mMultiple Airlines
lun. 9/2910:45 pmSAN - GCM
1 stop15h 20mMultiple Airlines
Deal found 9/14$8,660

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cayman Islands to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
Use the filters below to find and compare flights from the Cayman Islands to San Diego that are best for you.

Fly from

Cayman Islands

Fly to

San Diego

Route

Depart

Return

Price

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

mar. 3/10

1:50 pm-9:47 pm

1 stop9h 57m

San Diego

mié. 3/11

10:30 pm-12:45 pm

1 stop12h 15m

$496

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

mié. 10/22

12:25 pm-10:56 am

1 stop24h 31m

San Diego

dom. 10/26

10:45 pm-11:10 am

1 stop10h 25m

$496

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

mar. 3/10

8:30 am-6:32 pm

2 stops12h 02m

San Diego

mié. 3/11

7:52 pm-1:20 pm

2 stops15h 28m

$610

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

vie. 11/14

1:50 pm-9:13 pm

1 stop10h 23m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

vie. 11/14

5:45 pm-1:04 pm

2 stops22h 19m

$296

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

vie. 11/14

1:20 pm-11:07 pm

1 stop12h 47m

$692

George TownSan Diego

GCM - SAN

GCMSAN

George Town Owen Roberts Intl

vie. 11/14

11:25 am-4:20 pm

3 stops31h 55m

$1,031

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Best time to book a flight from Cayman Islands to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Cayman Islands with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Cayman Islands to San Diego
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated septiembre 16, 2025.
See what other customers who have flown with American Airlines from the Cayman Islands to San Diego have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Comfort

7.2

Crew

8.0

Overall

7.2

Food

6.4

Reviews

1 / 20
2.0
Mediocre

Nordia,Sep 2025

KIN - MIA

We were to land in Miami sometime after 3pm but couldn’t due to bad weather, we flew around for 2 hrs until we had to land in Forth Myers to refuel, we had to sit another 2 hrs at Forth Myers until given the clearance to refuel, we were hungry, thirsty and frustrated at that point. All the had on the flight to offer was a small plastic glass of water and a pack of biscoff, I requested a cup of tea and was told none was there. We were basically at another airport and not one of the staff could consider that the passengers might be hungry or thirsty being on a plane for around 8 hrs, which you weren’t prepared for, at least find some hot water on board.

Related info for your journey

Find useful and relevant information for your journey from Cayman Islands to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Cayman Islands?

    Most people fly into San Diego (SAN) if they book a flight to San Diego from Cayman Islands. San Diego is conveniently located just 2.6 mi from San Diego’s city center.

  • How long is the flight from Cayman Islands to San Diego?

    Airlines like United Airlines and American Airlines fly from Cayman Islands to San Diego in about 9h 57m. The time it takes to get you to your destination can typically vary by up to 14h 34m. There are 2395 mi between Cayman Islands and San Diego. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Cayman Islands to San Diego one-way?

    The cheapest airlines for a one-way flight from Cayman Islands to San Diego are Delta ($296), United Airlines ($296), and American Airlines ($692).

  • Can I find deals for flights from Cayman Islands to San Diego that include hotel bookings?

    Yes. In addition to deals on Cayman Islands to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cayman Islands to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cayman Islands to San Diego.

  • Can I find deals for business class flights from Cayman Islands to San Diego?

    Yes. Cheapflights offers flight deals from Cayman Islands to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cayman Islands to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Cayman Islands to San Diego (average of $286). Flying from Cayman Islands to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
La Mesa
Poway
Lemon Grove
Coronado
Imperial Beach
National City

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Top airline flying from Cayman Islands to San Diego

Discover the top airline that operate flights from Cayman Islands to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$495Average$650FlexibilityNo cancel feeOn-time71%

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