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$174+ Cheap flights from Biloxi, MS to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/19. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SAN
Apr 17 — Apr 241
Fri 4/17
Fri 4/24
1 adult, Economy
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Cheap flight deals from Biloxi to San Diego

Cheapest flights from Biloxi to San Diego
Explore the most affordable flight options available from Biloxi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 18, 2026.

This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:55 pm
GPT
-
SAN
1 stop7h 30m
Delta
Mon 4/2710:30 pm
SAN
-
GPT
1 stop8h 54m
Delta
Deal found 3/15$297
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/277:37 pm
GPT
-
SAN
1 stop6h 19m
American Airlines
Wed 5/61:36 pm
SAN
-
GPT
1 stop8h 22m
American Airlines
Deal found 3/18$313
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:57 pm
GPT
-
SAN
1 stop7h 12m
Delta
Mon 4/139:45 pm
SAN
-
GPT
1 stop9h 39m
Delta
Deal found 3/15$328
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:40 am
GPT
-
SAN
1 stop29h 37m
Multiple Airlines
Wed 5/66:25 am
SAN
-
GPT
2 stops34h 45m
Multiple Airlines
Deal found 3/18$334
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:50 pm
GPT
-
SAN
1 stop6h 09m
American Airlines
Tue 6/21:21 pm
SAN
-
GPT
1 stop8h 40m
American Airlines
Deal found 3/16$339
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:57 pm
GPT
-
SAN
1 stop7h 12m
Delta
Fri 4/179:45 pm
SAN
-
GPT
1 stop9h 39m
Delta
Deal found 3/15$358
This Delta deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/85:57 pm
GPT
-
SAN
1 stop7h 12m
Delta
Tue 4/149:45 pm
SAN
-
GPT
1 stop9h 39m
Delta
Deal found 3/15$359
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:03 pm
GPT
-
SAN
1 stop6h 57m
American Airlines
Sat 5/239:25 pm
SAN
-
GPT
1 stop10h 49m
American Airlines
Deal found 3/18$369
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:21 am
GPT
-
SAN
1 stop14h 51m
Multiple Airlines
Tue 6/212:54 pm
SAN
-
GPT
2 stops52h 16m
Multiple Airlines
Deal found 3/17$370
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:40 am
GPT
-
SAN
1 stop29h 37m
Multiple Airlines
Thu 4/3012:25 pm
SAN
-
GPT
2 stops18h 35m
Multiple Airlines
Deal found 3/18$384
This Kiwi.com deal was found by Cheapflights users on 3/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:40 am
GPT
-
SAN
1 stop10h 16m
Multiple Airlines
Fri 4/2412:25 pm
SAN
-
GPT
2 stops52h 15m
Multiple Airlines
Deal found 3/14$386

Find flight deals from Biloxi to San Diego

Keep the following information in mind while searching for Biloxi to San Diego flight deals. Data was last updated March 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$297
(Delta)

One-way from

$174
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$398
Provider with most accurate pricing for Gulfport Biloxi Regional-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-San Diego flights.
Search Deals
From Biloxi to San Diego
Search Deals
One-way flight from Biloxi to San Diego
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($91 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($25 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
Use the filters below to find and compare flights from Biloxi to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Tue 8/4

6:00 am-1:44 pm

1 stop9h 44m

San Diego

Mon 8/10

10:40 pm-9:35 am

1 stop8h 55m

$297

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Wed 4/22

5:55 pm-11:25 pm

1 stop7h 30m

San Diego

Mon 4/27

10:30 pm-9:24 am

1 stop8h 54m

$377

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 5/28

6:02 pm-11:27 pm

1 stop7h 25m

San Diego

Wed 6/3

12:41 pm-9:51 pm

1 stop7h 10m

$452

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Tue 5/19

7:07 am-5:19 pm

2 stops12h 12m

San Diego

Sat 5/23

6:20 am-4:11 pm

2 stops7h 51m

$456

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 6/4

6:02 pm-11:27 pm

1 stop7h 25m

San Diego

Mon 6/8

10:40 pm-9:37 am

1 stop8h 57m

$498
Quickest round-trip

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 7/9

2:00 pm-5:41 pm

1 stop5h 41m

San Diego

Tue 7/14

6:15 am-4:11 pm

1 stop7h 56m

$505

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Mon 4/27

2:05 pm-8:12 pm

2 stops8h 07m

San Diego

Wed 5/6

6:32 am-7:53 pm

2 stops11h 21m

$522

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Mon 4/20

2:05 pm-11:59 pm

2 stops11h 54m

San Diego

Fri 4/24

7:14 pm-2:13 pm

2 stops16h 59m

$547

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Wed 4/22

2:05 pm-12:29 am

2 stops12h 24m

San Diego

Mon 4/27

6:15 am-4:13 pm

1 stop7h 58m

$547

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 4/18

7:10 am-5:16 pm

2 stops12h 06m

San Diego

Wed 4/22

7:14 pm-4:13 pm

2 stops18h 59m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/16

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Best time to book a flight from Biloxi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to San Diego

What is the cheapest month to book a flight from Biloxi to San Diego?

Currently, May is the cheapest month in which you can book a flight from Biloxi to San Diego (average of $88). Flying from Biloxi to San Diego in October is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to SAN?

Find hourly flight availability from Biloxi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 18, 2026.

When flying from Biloxi to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated March 18, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Biloxi to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,435 reviews

Overall

7.4

Crew

8.1

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
United Airlines
7.4
Good
9,435 reviews
United Airlines
7.4
Good
9,435 reviews

Overall

7.4

Crew

8.1

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.
American Airlines
7.1
Good
11,468 reviews
United Airlines
7.4
Good
9,435 reviews

Overall

7.4

Crew

8.1

Entertainment

7.1

Comfort

7.3

Boarding

7.7

Food

6.6

Reviews

1 / 20
10.0
Excellent

Anonymous,Sep 2025

FRA - SFO

Lufthansa was amazing, I wish United States based airlines operated like them.

Related info for your journey

Find useful and relevant information for your journey from Biloxi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Biloxi?

    If you book a flight to San Diego from Biloxi, you will be flying to San Diego, which is the city’s only airport. San Diego (SAN) is located 2.6 mi from the center of San Diego. There are 0 flights from Biloxi to San Diego per day from 5 different airlines.

  • How popular is this Biloxi to San Diego flight route?

    Flights from Biloxi to San Diego have been viewed 1 times in the past calendar month.

  • How long is the flight from Biloxi to San Diego?

    For as low as $297, Delta can have you in San Diego from Biloxi in 9h 44m. Biloxi and San Diego are separated by a distance of 1658 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Biloxi to San Diego one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $138. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Biloxi to San Diego for a low price.

  • What are the cheapest flights from Biloxi to San Diego?

    Looking for the cheapest flight from Biloxi to San Diego? While on average our users pay $380, our data indicates the cheapest price to be $144. The most popular route (Gulfport Biloxi Regional - San Diego), is priced around $377.

  • Can I find deals for flights from Biloxi to San Diego that include hotel bookings?

    Yes. In addition to deals on Biloxi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to San Diego.

  • Can I find deals for business class flights from Biloxi to San Diego?

    Yes. Cheapflights offers flight deals from Biloxi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to San Diego?

    Currently, May is the cheapest month in which you can book a flight from Biloxi to San Diego (average of $88). Flying from Biloxi to San Diego in October is currently the most expensive (average of $259). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Top 5 airlines flying from Biloxi to San Diego

Discover the top 5 airlines that operate flights from Biloxi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$84Average$199FlexibilityNo cancel feeOn-time65%
DeltaCheapest$133Average$302FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$196Average$401FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$236Average$409FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$266Average$467FlexibilityNo cancel feeOn-time63%

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