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$215+ Cheap flights from Biloxi, MS to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
MSY — SAN
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Find flight deals from Biloxi to San Diego

Cheapest flights from Biloxi to San Diego
Explore the most affordable flight options available from Biloxi to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:01 pmGPT - SAN
1 stop7h 34mDelta
Sun 12/146:15 amSAN - GPT
1 stop9h 01mDelta
Deal found 10/29$289
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:52 amGPT - SAN
2 stops11h 02mUnited Airlines
Sat 11/158:00 amSAN - GPT
1 stop6h 02mUnited Airlines
Deal found 10/27$344
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:53 pmGPT - SAN
1 stop8h 20mDelta
Mon 11/1710:30 pmSAN - GPT
1 stop9h 19mDelta
Deal found 10/29$359
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/812:48 pmGPT - SAN
1 stop10h 12mAmerican Airlines
Sat 11/158:25 amSAN - GPT
1 stop7h 15mAmerican Airlines
Deal found 10/27$363
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:52 amGPT - SAN
2 stops11h 02mUnited Airlines
Mon 11/178:00 amSAN - GPT
1 stop6h 02mUnited Airlines
Deal found 10/29$364
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/223:30 pmGPT - SAN
1 stop7h 45mDelta
Sun 11/236:24 amSAN - GPT
1 stop8h 49mDelta
Deal found 10/27$374
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:52 amGPT - SAN
2 stops10h 00mUnited Airlines
Tue 12/21:53 pmSAN - GPT
1 stop5h 29mUnited Airlines
Deal found 10/28$394

Cheap flight deals from Biloxi to San Diego

Keep the following information in mind while searching for Biloxi to San Diego flight deals. Data was last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$289
(Delta)

One-way from

$215
(Delta)

Popular in

December

Cheapest in

August

Average price

$651
Provider with most accurate pricing for Gulfport Biloxi Regional-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gulfport Biloxi Regional-San Diego flights.
Search Deals
From Biloxi to San Diego
Search Deals
One-way flight from Biloxi to San Diego
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($93 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($31 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Biloxi to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Biloxi to San Diego that are best for you.

Fly from

Biloxi

Fly to

San Diego

Route

Depart

Return

Price

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 12/12

6:01 pm-11:35 pm

1 stop7h 34m

San Diego

Sun 12/14

6:15 am-5:16 pm

1 stop9h 01m

$289

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 2/20

6:00 pm-11:11 pm

1 stop7h 11m

San Diego

Sat 2/28

10:40 pm-9:41 am

1 stop9h 01m

$289

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 2/20

4:55 pm-11:40 pm

2 stops8h 45m

San Diego

Sat 2/28

8:00 am-4:01 pm

1 stop6h 01m

$294

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Mon 2/23

4:55 pm-10:00 pm

1 stop7h 05m

San Diego

Sat 2/28

8:00 am-4:01 pm

1 stop6h 01m

$314

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Wed 2/18

6:30 am-1:36 pm

1 stop9h 06m

San Diego

Sat 2/21

12:11 pm-11:59 pm

1 stop9h 48m

$339

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Tue 11/11

11:52 am-8:54 pm

2 stops11h 02m

San Diego

Sat 11/15

8:00 am-4:02 pm

1 stop6h 02m

$344

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Thu 11/13

2:53 pm-9:13 pm

1 stop8h 20m

San Diego

Mon 11/17

10:30 pm-9:49 am

1 stop9h 19m

$359

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Sat 11/8

6:10 pm-10:20 pm

1 stop6h 10m

San Diego

Sat 11/15

8:25 am-5:40 pm

1 stop7h 15m

$373

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 4/10

6:00 pm-11:11 pm

1 stop7h 11m

$215

GulfportSan Diego

GPT - SAN

GPTSAN

Gulfport Biloxi Regional

Fri 12/5

6:01 pm-11:35 pm

1 stop7h 34m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/28

Showing 1-10 of 15 results
1
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Best time to book a flight from Biloxi to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Biloxi with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Biloxi to San Diego

What is the cheapest month to book a flight from Biloxi to San Diego?

Currently, May is the cheapest month in which you can book a flight from Biloxi to San Diego (average of $88). Flying from Biloxi to San Diego in October is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from B1L to SAN?

Find hourly flight availability from Biloxi to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s optimal to fly from Biloxi to San Diego in the evening. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight in the morning.

What is the cheapest day to fly from Biloxi to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Biloxi to San Diego. Price data was last updated on November 18, 2024.

Travelers seeking maximum savings on their Biloxi to San Diego flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated October 29, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Biloxi to San Diego by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Comfort

7.9

Boarding

8.2

Overall

7.9

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

TUS - LAX

Delta has consistently been the best U.S. airline for my travels and this flight was no exception

Related info for your journey

Find useful and relevant information for your journey from Biloxi to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Biloxi?

    If you book a flight to San Diego from Biloxi, you will be flying to San Diego, which is the city’s only airport. San Diego (SAN) is located 2.6 mi from the center of San Diego. There are 0 flights from Biloxi to San Diego per day from 6 different airlines.

  • How popular is this Biloxi to San Diego flight route?

    Flights from Biloxi to San Diego have been viewed 3 times in the past calendar month.

  • How long is the flight from Biloxi to San Diego?

    For as low as $289, Delta can have you in San Diego from Biloxi in 7h 34m. Biloxi and San Diego are separated by a distance of 1658 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest flights from Biloxi to San Diego?

    Looking for the cheapest flight from Biloxi to San Diego? While on average our users pay $408, our data indicates the cheapest price to be $183. The most popular route (Gulfport Biloxi Regional - San Diego), is priced around $289.

  • Can I find deals for flights from Biloxi to San Diego that include hotel bookings?

    Yes. In addition to deals on Biloxi to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Biloxi to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Biloxi to San Diego.

  • Can I find deals for business class flights from Biloxi to San Diego?

    Yes. Cheapflights offers flight deals from Biloxi to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Biloxi to San Diego?

    Currently, May is the cheapest month in which you can book a flight from Biloxi to San Diego (average of $88). Flying from Biloxi to San Diego in October is currently the most expensive (average of $267). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
La Mesa
Poway
Lemon Grove
National City

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Top 6 airlines flying from Biloxi to San Diego

Discover the top 6 airlines that operate flights from Biloxi to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$128Average$218FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$151Average$209FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$216Average$410FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$250Average$453FlexibilityNo cancel feeOn-time69%
DeltaCheapest$256Average$303FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$291Average$483FlexibilityNo cancel feeOn-time63%

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