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$144+ Cheap flights from Myrtle Beach to San Antonio (MYR - SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAT
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Myrtle Beach to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 15, 2025.

Round-trip from

$349
(Mytrip)

One-way from

$144
(Kiwi.com)

Popular in

April

Cheapest in

May

Average price

$386
From Myrtle Beach Intl to San Antonio
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One-way flight from Myrtle Beach Intl to San Antonio
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Highest demand for flights based on searches. 3% potential increase in price ($15 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Myrtle Beach to San Antonio

Cheapest flights from Myrtle Beach to San Antonio
Explore the most affordable flight options available from Myrtle Beach to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/267:17 pmMYR - SAT
3 stops25h 15mSpirit Airlines
Sat 10/48:37 pmSAT - MYR
2 stops26h 19mSpirit Airlines
Deal found 9/13$349
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/144:47 pmMYR - SAT
1 stop6h 52mAmerican Airlines
Fri 10/172:26 pmSAT - MYR
1 stop6h 24mAmerican Airlines
Deal found 9/14$352
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/284:04 pmMYR - SAT
2 stops25h 26mMultiple Airlines
Thu 10/27:17 pmSAT - MYR
1 stop23h 49mMultiple Airlines
Deal found 9/13$357
This American Airlines deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/185:21 amMYR - SAT
1 stop5h 00mAmerican Airlines
Wed 10/223:02 pmSAT - MYR
1 stop4h 45mAmerican Airlines
Deal found 9/13$363
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/109:25 pmMYR - SAT
2 stops20h 12mMultiple Airlines
Sun 10/127:35 pmSAT - MYR
1 stop23h 29mMultiple Airlines
Deal found 9/14$383
This American Airlines deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/105:59 pmMYR - SAT
1 stop5h 58mAmerican Airlines
Sun 10/126:05 amSAT - MYR
1 stop7h 18mAmerican Airlines
Deal found 9/14$391
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/264:04 pmMYR - SAT
2 stops23h 23mMultiple Airlines
Sun 9/282:54 pmSAT - MYR
1 stop20h 03mMultiple Airlines
Deal found 9/13$397
This Kiwi.com deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/287:36 pmMYR - SAT
1 stop23h 36mSpirit Airlines
Thu 10/27:17 pmSAT - MYR
1 stop23h 49mSpirit Airlines
Deal found 9/13$418
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/296:00 amMYR - SAT
1 stop6h 19mDelta
Fri 10/36:11 pmSAT - MYR
1 stop4h 38mDelta
Deal found 9/14$467

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Myrtle Beach to San Antonio that are best for you.

Fly from

Myrtle Beach

Fly to

San Antonio

Route

Depart

Return

Price

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Sun 9/28

4:04 pm-4:30 pm

2 stops25h 26m

San Antonio

Thu 10/2

7:17 pm-8:06 pm

1 stop23h 49m

$357

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Sat 10/18

5:21 am-9:21 am

1 stop5h 00m

San Antonio

Wed 10/22

3:02 pm-8:47 pm

1 stop4h 45m

$363

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Fri 10/10

5:59 pm-10:57 pm

1 stop5h 58m

San Antonio

Sun 10/12

6:05 am-2:23 pm

1 stop7h 18m

$391

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Mon 9/29

6:00 am-6:12 pm

2 stops13h 12m

San Antonio

Fri 10/3

7:17 pm-8:06 pm

1 stop23h 49m

$397

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Fri 9/26

4:04 pm-2:27 pm

2 stops23h 23m

San Antonio

Sun 9/28

2:54 pm-11:57 am

1 stop20h 03m

$397

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 10/14

4:47 pm-10:39 pm

1 stop6h 52m

San Antonio

Fri 10/17

2:26 pm-9:50 pm

1 stop6h 24m

$403

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Tue 3/10

6:00 am-10:00 am

1 stop5h 00m

San Antonio

Wed 3/11

4:25 pm-11:35 pm

1 stop6h 10m

$407

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Sun 9/28

7:36 pm-6:12 pm

1 stop23h 36m

San Antonio

Thu 10/2

7:17 pm-8:06 pm

1 stop23h 49m

$418

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Fri 9/26

7:17 pm-7:32 pm

3 stops25h 15m

San Antonio

Sat 10/4

8:37 pm-11:56 pm

3 stops26h 19m

$424

Myrtle BeachSan Antonio

MYR - SAT

MYRSAT

Myrtle Beach Intl

Mon 9/29

6:00 am-11:19 am

1 stop6h 19m

San Antonio

Fri 10/3

6:11 pm-11:49 pm

1 stop4h 38m

$467

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/13

Showing 1-10 of 21 results
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Best time to book a flight from Myrtle Beach to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to San Antonio

What is the cheapest month to book a flight from Myrtle Beach to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Antonio (average of $295). Flying from Myrtle Beach to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MYR to SAT?

Find hourly flight availability from Myrtle Beach to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Myrtle Beach to San Antonio, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 15% versus a flight in the evening.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated September 15, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Myrtle Beach to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Spirit Airlines
6.3
Okay
8,015 reviews
Southwest
8.0
Very good
4,242 reviews

Entertainment

7.5

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Myrtle Beach to San Antonio?

    American Airlines and Spirit Airlines can get you from Myrtle Beach to San Antonio in just under 5h. Your travel time can differ by up to 8h 12m. Myrtle Beach and San Antonio are separated by a distance of 1183 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Myrtle Beach to San Antonio round-trip?

    Spirit Airlines, at $193, was found to be the cheapest airline from Myrtle Beach to San Antonio.Alternate airlines to your destination round-trip include Delta and Southwest. You may be able to fly from Myrtle Beach to San Antonio for 50% less than the average price by searching for these airlines.

  • Can I find deals for flights from Myrtle Beach to San Antonio that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to San Antonio.

  • Can I find deals for business class flights from Myrtle Beach to San Antonio?

    Yes. Cheapflights offers flight deals from Myrtle Beach to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Myrtle Beach to San Antonio (average of $295). Flying from Myrtle Beach to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels
Kerrville

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Alternative routes for Myrtle Beach to San Antonio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Myrtle Beach to San Antonio

Discover the top 4 airlines that operate flights from Myrtle Beach to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$193Average$310FlexibilityNo cancel feeOn-time65%
DeltaCheapest$286Average$338FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$331Average$486FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$336Average$386FlexibilityNo cancel feeOn-time71%

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