$143+ Cheap flights from Myrtle Beach to San Antonio (MYR - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — SAT
Mar 25 — Apr 11
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Myrtle Beach to San Antonio
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Cheapest flights from Myrtle Beach to San AntonioExplore the most affordable flight options available from Myrtle Beach to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
Explore the most affordable flight options available from Myrtle Beach to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/1412:50 pm
MYR
- SAT
1 stop21h 34m
Multiple Airlines
Mon 5/1810:23 am
SAT
- MYR
1 stop24h 27m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/87:51 pm
MYR
- SAT
1 stop14h 20m
Multiple Airlines
Mon 5/1110:23 am
SAT
- MYR
1 stop24h 27m
Multiple Airlines
Deal found 2/21![Multiple Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:51 pm
MYR
- SAT
1 stop14h 20m
Spirit Airlines
Mon 5/46:00 am
SAT
- MYR
1 stop28h 50m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:20 pm
MYR
- SAT
1 stop7h 58m
Multiple Airlines
Mon 4/2710:26 am
SAT
- MYR
1 stop22h 15m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:30 am
MYR
- SAT
1 stop27h 42m
Multiple Airlines
Sat 2/282:13 pm
SAT
- MYR
1 stop18h 37m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:28 pm
MYR
- SAT
1 stop15h 59m
Multiple Airlines
Sun 3/2210:22 am
SAT
- MYR
1 stop26h 51m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$293
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:42 am
MYR
- SAT
2 stops13h 36m
Spirit Airlines
Mon 4/2710:26 am
SAT
- MYR
1 stop22h 15m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:20 pm
MYR
- SAT
1 stop7h 58m
Multiple Airlines
Fri 5/810:26 am
SAT
- MYR
1 stop22h 15m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$307
This Expedia deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:39 pm
MYR
- SAT
1 stop12h 20m
Spirit Airlines
Thu 3/1210:22 am
SAT
- MYR
1 stop6h 11m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$313
Best flights from Myrtle Beach to San AntonioDiscover carefully curated flight deals from Myrtle Beach to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
Discover carefully curated flight deals from Myrtle Beach to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:20 pm
MYR
- SAT
1 stop7h 58m
Multiple Airlines
Mon 4/2710:26 am
SAT
- MYR
1 stop22h 15m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/249:42 am
MYR
- SAT
2 stops13h 36m
Spirit Airlines
Mon 4/2710:26 am
SAT
- MYR
1 stop22h 15m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$304
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:54 pm
MYR
- SAT
1 stop6h 44m
Delta
Wed 4/85:10 am
SAT
- MYR
1 stop7h 21m
Delta
Deal found 2/21![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/243:45 pm
MYR
- SAT
2 stops8h 45m
Southwest
Mon 4/279:55 am
SAT
- MYR
2 stops7h 50m
Southwest
Deal found 2/21![Southwest logo]()
$393
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/203:20 pm
MYR
- SAT
1 stop22h 07m
Multiple Airlines
Mon 3/2310:22 am
SAT
- MYR
1 stop6h 11m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1012:39 pm
MYR
- SAT
2 stops21h 51m
Spirit Airlines
Sat 3/141:22 pm
SAT
- MYR
1 stop20h 43m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$370
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:28 pm
MYR
- SAT
2 stops18h 59m
Spirit Airlines
Mon 3/2310:22 am
SAT
- MYR
3 stops23h 43m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$400
Last-minute flights from Myrtle Beach to San AntonioDiscover last-minute flight deals from Myrtle Beach to San Antonio. Data last updated February 23, 2026 and is based on user searches.
Discover last-minute flight deals from Myrtle Beach to San Antonio. Data last updated February 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2610:30 am
MYR
- SAT
1 stop27h 42m
Multiple Airlines
Sat 2/282:13 pm
SAT
- MYR
1 stop18h 37m
Multiple Airlines
Deal found 2/20![Multiple Airlines logo]()
$281
This Mytrip deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/2612:39 pm
MYR
- SAT
1 stop12h 20m
Spirit Airlines
Sat 2/286:00 am
SAT
- MYR
3 stops25h 13m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$353
This Kiwi.com deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/711:54 am
MYR
- SAT
1 stop13h 05m
Spirit Airlines
Wed 3/116:00 am
SAT
- MYR
1 stop28h 05m
Spirit Airlines
Deal found 2/20![Spirit Airlines logo]()
$316
This Expedia deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/812:39 pm
MYR
- SAT
1 stop12h 20m
Spirit Airlines
Thu 3/1210:22 am
SAT
- MYR
1 stop6h 11m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/109:09 am
MYR
- SAT
1 stop25h 21m
Spirit Airlines
Sat 3/141:22 pm
SAT
- MYR
1 stop20h 43m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$329
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:28 pm
MYR
- SAT
1 stop15h 59m
Multiple Airlines
Sun 3/2210:22 am
SAT
- MYR
1 stop26h 51m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$293
This Mytrip deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:28 pm
MYR
- SAT
1 stop15h 59m
Spirit Airlines
Mon 3/2310:22 am
SAT
- MYR
1 stop6h 11m
Spirit Airlines
Deal found 2/19![Spirit Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/203:20 pm
MYR
- SAT
1 stop22h 07m
Multiple Airlines
Mon 3/2310:22 am
SAT
- MYR
1 stop6h 11m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2412:05 pm
MYR
- SAT
1 stop25h 22m
Spirit Airlines
Fri 3/2710:22 am
SAT
- MYR
1 stop6h 11m
Spirit Airlines
Deal found 2/21![Spirit Airlines logo]()
$348
One-way flights from Myrtle Beach to San AntonioSearch for one-way flight options from Myrtle Beach to San Antonio. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
Search for one-way flight options from Myrtle Beach to San Antonio. Find affordable one-way fares based on user searches. Data last updated February 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:28 pm
MYR
- SAT
2 stops28h 50m
Spirit Airlines
Deal found 2/22![Spirit Airlines logo]()
$143
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/143:49 pm
MYR
- SAT
1 stop5h 41m
Delta
Deal found 2/22![Delta logo]()
$168
Find flight deals from Myrtle Beach to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Myrtle Beach (MYR) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $238 (Kiwi.com) |
One-way from | $143 (Kiwi.com) |
Popular in | April |
Cheapest in | May |
Average price | $361 |
Cheapflights Fare Finder
Customize your flight search to find flights from Myrtle Beach to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
Use the filters below to find and compare flights from Myrtle Beach to San Antonio that are best for you.
Fly from
Myrtle Beach
Fly to
San Antonio
Route
Depart
Return
Price
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Fri 4/24
3:20 pm-10:18 pm
1 stop7h 58m
San Antonio
Mon 4/27
10:26 am-9:41 am
1 stop22h 15m
$279
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Fri 4/24
9:42 am-10:18 pm
2 stops13h 36m
San Antonio
Mon 4/27
10:26 am-9:41 am
1 stop22h 15m
$304
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Fri 3/20
3:20 pm-12:27 pm
1 stop22h 07m
San Antonio
Mon 3/23
10:22 am-5:33 pm
1 stop6h 11m
$365
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Tue 3/31
6:54 pm-12:38 am
1 stop6h 44m
San Antonio
Wed 4/8
5:10 am-1:31 pm
1 stop7h 21m
$367
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Tue 3/10
12:39 pm-9:30 am
2 stops21h 51m
San Antonio
Sat 3/14
1:22 pm-11:05 am
1 stop20h 43m
$370
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Fri 4/24
3:45 pm-11:30 pm
2 stops8h 45m
San Antonio
Mon 4/27
9:55 am-6:45 pm
2 stops7h 50m
$393
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Fri 3/20
6:28 pm-12:27 pm
2 stops18h 59m
San Antonio
Mon 3/23
10:22 am-11:05 am
3 stops23h 43m
$400
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Tue 4/14
6:28 pm-10:18 pm
2 stops28h 50m
$143
Myrtle BeachSan Antonio
MYR - SAT
MYRSAT
Myrtle Beach Intl
Tue 4/14
3:49 pm-8:30 pm
1 stop5h 41m
$168
Compare providers for flights from Myrtle Beach to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Myrtle Beach to San Antonio in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Myrtle Beach-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Myrtle Beach-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Myrtle Beach-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Myrtle Beach-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Myrtle Beach-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Myrtle Beach to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Myrtle Beach with our price prediction graph.
MYR-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Myrtle Beach to San Antonio
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated February 23, 2026.
Peruse reviews from past customers who have flown with Southwest, Delta, and American Airlines from Myrtle Beach to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Overall
8.0
Comfort
8.0
Entertainment
7.5
Boarding
8.1
Food
7.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreThomas,Dec 2025
SEA - DEN
Related info for your journey
Find useful and relevant information for your journey from Myrtle Beach to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Myrtle Beach and San Antonio flights
Browse other Myrtle Beach and San Antonio flight options. Last updated on February 23, 2026.
Other flights from Myrtle Beach
Browse through other flights departing from Myrtle Beach. Flights are based on user searches made on Cheapflights and were last updated on February 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 23, 2026.
Top 4 airlines flying from Myrtle Beach to San Antonio
Discover the top 4 airlines that operate flights from Myrtle Beach to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$181 | Average$254 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$273 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$286 | Average$352 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$327 | Average$446 | FlexibilityNo cancel fee | On-time63% |