$140+ Cheap flights from Louisville to San Antonio (SDF - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/29. Fares are subject to change and may not be available on all flights or dates of travel.
SDF — SAT
Jun 9 — Jun 161
Round-trip
1 adult, Economy
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Find cheap flights from Louisville to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Louisville to San Antonio
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Best
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Cheapest flights from Louisville to San AntonioExplore the most affordable flight options available from Louisville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
Explore the most affordable flight options available from Louisville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 10, 2026.
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:45 am
SDF
- SAT
1 stop4h 50m
Southwest
Tue 6/307:00 am
SAT
- SDF
1 stop4h 05m
Southwest
Deal found 5/8![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:55 am
SDF
- SAT
1 stop5h 12m
American Airlines
Mon 10/266:40 am
SAT
- SDF
1 stop6h 45m
American Airlines
Deal found 5/6![American Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:22 am
SDF
- SAT
1 stop5h 49m
United Airlines
Thu 8/274:13 pm
SAT
- SDF
1 stop5h 01m
United Airlines
Deal found 5/7![United Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:45 am
SDF
- SAT
1 stop7h 30m
Southwest
Wed 6/37:25 am
SAT
- SDF
2 stops6h 40m
Southwest
Deal found 5/6![Southwest logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:06 pm
SDF
- SAT
1 stop14h 04m
Breeze Airways
Fri 5/2911:30 am
SAT
- SDF
2 stops20h 06m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$340
Best flights from Louisville to San AntonioDiscover carefully curated flight deals from Louisville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
Discover carefully curated flight deals from Louisville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 10, 2026.
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:22 am
SDF
- SAT
1 stop5h 49m
United Airlines
Thu 8/274:13 pm
SAT
- SDF
1 stop5h 01m
United Airlines
Deal found 5/7![United Airlines logo]()
$335
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/247:45 pm
SDF
- SAT
1 stop4h 55m
Southwest
Sun 6/287:30 am
SAT
- SDF
1 stop6h 55m
Southwest
Deal found 5/6![Southwest logo]()
$367
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:49 pm
SDF
- SAT
1 stop4h 16m
American Airlines
Mon 7/1311:03 am
SAT
- SDF
1 stop6h 56m
American Airlines
Deal found 5/8![American Airlines logo]()
$407
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:00 am
SDF
- SAT
1 stop5h 58m
United Airlines
Sun 8/304:13 pm
SAT
- SDF
1 stop5h 01m
United Airlines
Deal found 5/7![United Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/187:55 am
SDF
- SAT
1 stop5h 55m
Southwest
Mon 9/283:25 pm
SAT
- SDF
1 stop4h 05m
Southwest
Deal found 5/5![Southwest logo]()
$371
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:20 am
SDF
- SAT
2 stops7h 15m
Southwest
Mon 10/1211:45 am
SAT
- SDF
1 stop6h 45m
Southwest
Deal found 5/6![Southwest logo]()
$376
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:05 am
SDF
- SAT
2 stops8h 30m
Southwest
Sun 8/3012:20 pm
SAT
- SDF
2 stops11h 40m
Southwest
Deal found 5/7![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/511:50 am
SDF
- SAT
1 stop7h 25m
Southwest
Sun 8/912:20 pm
SAT
- SDF
1 stop3h 50m
Southwest
Deal found 5/9![Southwest logo]()
$381
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/148:00 pm
SDF
- SAT
1 stop5h 20m
Southwest
Fri 6/195:40 am
SAT
- SDF
2 stops7h 45m
Southwest
Deal found 5/10![Southwest logo]()
$412
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/161:10 pm
SDF
- SAT
1 stop8h 50m
Southwest
Thu 7/235:30 am
SAT
- SDF
2 stops5h 30m
Southwest
Deal found 5/6![Southwest logo]()
$412
Last-minute flights from Louisville to San AntonioDiscover last-minute flight deals from Louisville to San Antonio. Data last updated May 10, 2026 and is based on user searches.
Discover last-minute flight deals from Louisville to San Antonio. Data last updated May 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:06 pm
SDF
- SAT
1 stop14h 04m
Breeze Airways
Fri 5/2911:30 am
SAT
- SDF
2 stops20h 06m
Breeze Airways
Deal found 5/8![Breeze Airways logo]()
$340
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/287:45 pm
SDF
- SAT
1 stop4h 21m
American Airlines
Wed 6/35:52 pm
SAT
- SDF
1 stop5h 36m
American Airlines
Deal found 5/6![American Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:45 am
SDF
- SAT
1 stop7h 30m
Southwest
Wed 6/37:25 am
SAT
- SDF
2 stops6h 40m
Southwest
Deal found 5/6![Southwest logo]()
$336
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/75:00 am
SDF
- SAT
1 stop5h 10m
American Airlines
Tue 6/95:35 pm
SAT
- SDF
1 stop4h 44m
American Airlines
Deal found 5/7![American Airlines logo]()
$367
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/2310:45 am
SDF
- SAT
1 stop4h 50m
Southwest
Tue 6/307:00 am
SAT
- SDF
1 stop4h 05m
Southwest
Deal found 5/8![Southwest logo]()
$327
One-way flights from Louisville to San AntonioSearch for one-way flight options from Louisville to San Antonio. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
Search for one-way flight options from Louisville to San Antonio. Find affordable one-way fares based on user searches. Data last updated May 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:06 pm
SDF
- SAT
1 stop14h 09m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:55 pm
SDF
- SAT
3 stops16h 55m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:55 pm
SDF
- SAT
3 stops16h 55m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:06 pm
SDF
- SAT
1 stop14h 09m
Breeze Airways
Deal found 5/9![Breeze Airways logo]()
$162
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/306:51 am
SDF
- SAT
1 stop7h 39m
American Airlines
Deal found 5/5![American Airlines logo]()
$164
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/305:25 pm
SDF
- SAT
2 stops6h 30m
Southwest
Deal found 5/5![Southwest logo]()
$169
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:05 am
SDF
- SAT
1 stop6h 13m
Delta
Deal found 5/9![Delta logo]()
$178
This United Airlines deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/2611:00 am
SDF
- SAT
2 stops7h 43m
United Airlines
Deal found 5/9![United Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2810:39 am
SDF
- SAT
2 stops30h 34m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$192
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/185:26 pm
SDF
- SAT
1 stop5h 55m
Delta
Deal found 5/9![Delta logo]()
$197
This American Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/177:49 pm
SDF
- SAT
1 stop5h 10m
American Airlines
Deal found 5/6![American Airlines logo]()
$204
This Delta deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:05 am
SDF
- SAT
1 stop5h 04m
Delta
Deal found 5/7![Delta logo]()
$209
Find flight deals from Louisville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Louisville (SDF) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $327 (Southwest) |
One-way from | $140 (Kiwi.com) |
Popular in | September |
Cheapest in | August |
Average price | $375 |
Cheapflights Fare Finder
Customize your flight search to find flights from Louisville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
Use the filters below to find and compare flights from Louisville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Mon 8/24
7:22 am-12:11 pm
1 stop5h 49m
San Antonio
Thu 8/27
4:13 pm-10:14 pm
1 stop5h 01m
$335
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Wed 6/24
7:45 pm-11:40 pm
1 stop4h 55m
San Antonio
Sun 6/28
7:30 am-3:25 pm
1 stop6h 55m
$367
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Wed 8/26
6:00 am-10:58 am
1 stop5h 58m
San Antonio
Sun 8/30
4:13 pm-10:14 pm
1 stop5h 01m
$367
Quickest round-trip
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Fri 9/18
7:55 am-12:50 pm
1 stop5h 55m
San Antonio
Mon 9/28
3:25 pm-8:30 pm
1 stop4h 05m
$371
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Fri 10/9
7:20 am-1:35 pm
2 stops7h 15m
San Antonio
Mon 10/12
11:45 am-7:30 pm
1 stop6h 45m
$376
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Wed 8/26
7:05 am-2:35 pm
2 stops8h 30m
San Antonio
Sun 8/30
12:20 pm-1:00 am
2 stops11h 40m
$377
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Wed 8/5
11:50 am-6:15 pm
1 stop7h 25m
San Antonio
Sun 8/9
12:20 pm-5:10 pm
1 stop3h 50m
$381
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Thu 7/9
7:49 pm-11:05 pm
1 stop4h 16m
San Antonio
Mon 7/13
11:03 am-6:59 pm
1 stop6h 56m
$407
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Sun 6/14
8:00 pm-12:20 am
1 stop5h 20m
San Antonio
Fri 6/19
5:40 am-2:25 pm
2 stops7h 45m
$412
LouisvilleSan Antonio
SDF - SAT
SDFSAT
Louisville Intl
Thu 7/16
1:10 pm-9:00 pm
1 stop8h 50m
San Antonio
Thu 7/23
5:30 am-12:00 pm
2 stops5h 30m
$412
Showing 1-10 of 20 resultsSorted by cheapest first
Compare providers for flights from Louisville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Louisville to San Antonio in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Louisville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Louisville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Louisville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Louisville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Louisville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Louisville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Louisville with our price prediction graph.
SDF-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Louisville to San Antonio
How far ahead should I book a flight from Louisville to San Antonio?
The price you pay for your flight from Louisville to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Louisville to San Antonio?
Currently, August is the cheapest month in which you can book a flight from Louisville to San Antonio (average of $316). Flying from Louisville to San Antonio in September is currently the most expensive (average of $581). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Louisville to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated May 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Louisville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Boarding
8.1
Comfort
8.0
Food
7.0
Overall
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Louisville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Complete your trip to San Antonio by adding a car rental and/or hotel reservation to your travel itinerary.
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Louisville and San Antonio flights
Browse other Louisville and San Antonio flight options. Last updated on May 10, 2026.
Other flights from Louisville
Browse through other flights departing from Louisville. Flights are based on user searches made on Cheapflights and were last updated on May 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 10, 2026.
Top 4 airlines flying from Louisville to San Antonio
Discover the top 4 airlines that operate flights from Louisville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$127 | Average$354 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$283 | Average$369 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$298 | Average$382 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$319 | Average$409 | FlexibilityNo cancel fee | On-time69% |