$142+ Cheap flights from Knoxville to San Antonio (TYS - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
Aug 31 — Sep 71
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to San Antonio with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to San Antonio
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to San AntonioExplore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 1, 2026.
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/53:35 pm
TYS
- SAT
1 stop4h 10m
Southwest
Tue 9/89:20 am
SAT
- TYS
1 stop4h 00m
Southwest
Deal found 7/29![Southwest logo]()
$298
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
TYS
- SAT
1 stop4h 43m
Delta
Wed 9/165:30 am
SAT
- TYS
1 stop4h 48m
Delta
Deal found 7/30![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:35 pm
TYS
- SAT
2 stops6h 15m
Southwest
Mon 8/2411:05 am
SAT
- TYS
1 stop6h 30m
Southwest
Deal found 7/29![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:55 pm
TYS
- SAT
2 stops8h 45m
Southwest
Sun 9/67:35 am
SAT
- TYS
1 stop5h 15m
Southwest
Deal found 7/27![Southwest logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:51 pm
TYS
- SAT
1 stop19h 05m
Multiple Airlines
Mon 8/249:51 am
SAT
- TYS
1 stop8h 14m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:55 pm
TYS
- SAT
2 stops8h 45m
Southwest
Thu 8/277:10 am
SAT
- TYS
2 stops9h 00m
Southwest
Deal found 7/29![Southwest logo]()
$327
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:51 am
TYS
- SAT
2 stops9h 19m
United Airlines
Wed 11/44:19 pm
SAT
- TYS
1 stop4h 38m
United Airlines
Deal found 7/28![United Airlines logo]()
$332
Best flights from Knoxville to San AntonioDiscover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
Discover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 1, 2026.
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:00 am
TYS
- SAT
1 stop4h 43m
Delta
Wed 9/165:30 am
SAT
- TYS
1 stop4h 48m
Delta
Deal found 7/27![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
TYS
- SAT
1 stop4h 20m
Southwest
Sat 8/2912:20 pm
SAT
- TYS
1 stop4h 20m
Southwest
Deal found 7/27![Southwest logo]()
$303
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:51 am
TYS
- SAT
2 stops9h 19m
United Airlines
Wed 11/44:19 pm
SAT
- TYS
1 stop4h 38m
United Airlines
Deal found 7/28![United Airlines logo]()
$332
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:12 pm
TYS
- SAT
1 stop7h 16m
Delta
Sun 9/65:20 am
SAT
- TYS
1 stop6h 08m
Delta
Deal found 7/27![Delta logo]()
$304
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am
TYS
- SAT
2 stops8h 05m
Southwest
Thu 8/277:10 am
SAT
- TYS
1 stop5h 15m
Southwest
Deal found 7/29![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:50 am
TYS
- SAT
2 stops8h 00m
Southwest
Tue 9/89:20 am
SAT
- TYS
2 stops9h 35m
Southwest
Deal found 7/29![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:16 pm
TYS
- SAT
1 stop5h 30m
Delta
Sun 9/66:25 am
SAT
- TYS
1 stop5h 03m
Delta
Deal found 8/1![Delta logo]()
$333
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:23 pm
TYS
- SAT
1 stop7h 10m
Delta
Fri 10/236:20 pm
SAT
- TYS
1 stop4h 39m
Delta
Deal found 7/27![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:05 pm
TYS
- SAT
2 stops8h 55m
Southwest
Mon 9/287:00 am
SAT
- TYS
1 stop4h 20m
Southwest
Deal found 7/30![Southwest logo]()
$338
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/237:21 pm
TYS
- SAT
1 stop6h 10m
Delta
Fri 11/277:50 am
SAT
- TYS
1 stop6h 28m
Delta
Deal found 7/27![Delta logo]()
$333
This Southwest deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:40 am
TYS
- SAT
2 stops10h 15m
Southwest
Wed 11/412:05 pm
SAT
- TYS
2 stops6h 40m
Southwest
Deal found 7/28![Southwest logo]()
$343
Last-minute flights from Knoxville to San AntonioDiscover last-minute flight deals from Knoxville to San Antonio. Data last updated August 1, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Antonio. Data last updated August 1, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/193:00 pm
TYS
- SAT
1 stop7h 25m
Southwest
Fri 8/2111:50 am
SAT
- TYS
1 stop7h 05m
Southwest
Deal found 7/31![Southwest logo]()
$333
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:51 pm
TYS
- SAT
1 stop19h 05m
Multiple Airlines
Mon 8/249:51 am
SAT
- TYS
1 stop8h 14m
Multiple Airlines
Deal found 7/30![Multiple Airlines logo]()
$317
This Southwest deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:05 pm
TYS
- SAT
2 stops8h 50m
Southwest
Mon 8/245:35 am
SAT
- TYS
2 stops13h 20m
Southwest
Deal found 7/30![Southwest logo]()
$349
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:35 pm
TYS
- SAT
1 stop4h 05m
Southwest
Mon 8/245:35 am
SAT
- TYS
1 stop6h 50m
Southwest
Deal found 7/29![Southwest logo]()
$298
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:55 pm
TYS
- SAT
2 stops8h 45m
Southwest
Thu 8/277:10 am
SAT
- TYS
2 stops9h 00m
Southwest
Deal found 7/29![Southwest logo]()
$327
This Delta deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/255:40 am
TYS
- SAT
1 stop6h 30m
Delta
Fri 8/285:45 pm
SAT
- TYS
1 stop5h 07m
Delta
Deal found 7/31![Delta logo]()
$342
This Southwest deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:00 am
TYS
- SAT
1 stop4h 20m
Southwest
Sat 8/2912:20 pm
SAT
- TYS
1 stop4h 20m
Southwest
Deal found 7/27![Southwest logo]()
$303
One-way flights from Knoxville to San AntonioSearch for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
Search for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated August 1, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:38 pm
TYS
- SAT
1 stop19h 20m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$142
This Southwest deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:35 pm
TYS
- SAT
1 stop4h 10m
Southwest
Deal found 8/1![Southwest logo]()
$165
This United Airlines deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:53 pm
TYS
- SAT
2 stops9h 51m
United Airlines
Deal found 8/1![United Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/137:00 am
TYS
- SAT
2 stops56h 20m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$176
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/25:40 am
TYS
- SAT
1 stop5h 07m
Delta
Deal found 7/30![Delta logo]()
$182
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am
TYS
- SAT
1 stop7h 11m
United Airlines
Deal found 7/31![United Airlines logo]()
$191
This Delta deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/135:40 am
TYS
- SAT
1 stop5h 07m
Delta
Deal found 8/1![Delta logo]()
$194
This Kiwi.com deal was found by Cheapflights users on 8/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/123:51 pm
TYS
- SAT
3 stops45h 07m
Multiple Airlines
Deal found 8/1![Multiple Airlines logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
- SAT
2 stops46h 44m
Multiple Airlines
Deal found 7/31![Multiple Airlines logo]()
$197
Find flight deals from Knoxville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $298 (Southwest) |
One-way from | $142 (Kiwi.com) |
Popular in | July |
Cheapest in | January |
Average price | $362 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 9/5
6:00 am-9:43 am
1 stop4h 43m
San Antonio
Wed 9/16
5:30 am-11:18 am
1 stop4h 48m
$303
Quickest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Wed 8/26
7:00 am-10:20 am
1 stop4h 20m
San Antonio
Sat 8/29
12:20 pm-5:40 pm
1 stop4h 20m
$303
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Tue 9/1
6:12 pm-12:28 am
1 stop7h 16m
San Antonio
Sun 9/6
5:20 am-12:28 pm
1 stop6h 08m
$304
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Tue 8/25
7:00 am-2:05 pm
2 stops8h 05m
San Antonio
Thu 8/27
7:10 am-1:25 pm
1 stop5h 15m
$308
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 9/5
6:50 am-1:50 pm
2 stops8h 00m
San Antonio
Tue 9/8
9:20 am-7:55 pm
2 stops9h 35m
$313
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 10/31
10:51 am-7:10 pm
2 stops9h 19m
San Antonio
Wed 11/4
4:19 pm-9:57 pm
1 stop4h 38m
$332
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Fri 9/4
2:16 pm-6:46 pm
1 stop5h 30m
San Antonio
Sun 9/6
6:25 am-12:28 pm
1 stop5h 03m
$333
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Mon 10/19
6:23 pm-12:33 am
1 stop7h 10m
San Antonio
Fri 10/23
6:20 pm-11:59 pm
1 stop4h 39m
$333
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Mon 11/23
7:21 pm-12:31 am
1 stop6h 10m
San Antonio
Fri 11/27
7:50 am-3:18 pm
1 stop6h 28m
$333
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Fri 9/25
2:05 pm-10:00 pm
2 stops8h 55m
San Antonio
Mon 9/28
7:00 am-12:20 pm
1 stop4h 20m
$338
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
TYS-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Antonio
What is the cheapest month to book a flight from Knoxville to San Antonio?
Currently, January is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $290). Flying from Knoxville to San Antonio in July is currently the most expensive (average of $578). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to San Antonio?
Airfare is below average for this route at the moment.
Knoxville to San Antonio flights typically cost between $308 and $376 in September.The cheapest round-trip price found within the last 5 days was $298 on Southwest (Sep 5-Sep 8).
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated August 1, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Boarding
8.1
Food
7.0
Overall
8.0
Comfort
8.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Knoxville
Popular flights
San Antonio flight routes
Alternative routes for Knoxville to San Antonio
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to San Antonio by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to San Antonio by cabin class
Find flights from Knoxville to San Antonio, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and San Antonio flights
Browse other Knoxville and San Antonio flight options. Last updated on August 1, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on August 1, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Other flights to San Antonio
Explore flights to San Antonio departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 1, 2026.
Top 4 airlines flying from Knoxville to San Antonio
Discover the top 4 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 1, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$236 | Average$335 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$264 | Average$430 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$268 | Average$351 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$299 | Average$488 | FlexibilityNo cancel fee | On-time63% |