$129+ Cheap flights from Knoxville to San Antonio (TYS - SAT)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/9. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — SAT
May 7 — May 141
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Knoxville to San AntonioExplore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
Explore the most affordable flight options available from Knoxville to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/217:13 am
TYS
- SAT
1 stop6h 54m
American Airlines
Sat 10/243:56 pm
SAT
- TYS
1 stop6h 34m
American Airlines
Deal found 4/2![American Airlines logo]()
$257
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:57 pm
TYS
- SAT
1 stop7h 31m
Delta
Sat 10/244:25 pm
SAT
- TYS
1 stop6h 21m
Delta
Deal found 4/2![Delta logo]()
$267
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:00 am
TYS
- SAT
1 stop5h 10m
American Airlines
Sat 6/66:15 am
SAT
- TYS
1 stop8h 34m
American Airlines
Deal found 4/6![American Airlines logo]()
$274
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
TYS
- SAT
2 stops9h 43m
United Airlines
Sat 5/96:02 pm
SAT
- TYS
1 stop4h 42m
United Airlines
Deal found 4/5![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:40 am
TYS
- SAT
2 stops6h 45m
Southwest
Sat 5/99:15 am
SAT
- TYS
2 stops8h 15m
Southwest
Deal found 4/5![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
TYS
- SAT
1 stop5h 12m
Delta
Wed 5/136:50 am
SAT
- TYS
1 stop6h 43m
Delta
Deal found 4/2![Delta logo]()
$290
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:40 am
TYS
- SAT
2 stops6h 45m
Southwest
Wed 5/137:00 am
SAT
- TYS
2 stops9h 10m
Southwest
Deal found 4/2![Southwest logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:56 am
TYS
- SAT
1 stop29h 20m
Multiple Airlines
Fri 5/155:26 pm
SAT
- TYS
1 stop16h 40m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:57 pm
TYS
- SAT
1 stop7h 31m
Delta
Wed 10/284:25 pm
SAT
- TYS
1 stop4h 20m
Delta
Deal found 4/2![Delta logo]()
$304
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:53 pm
TYS
- SAT
1 stop6h 05m
United Airlines
Tue 4/286:02 pm
SAT
- TYS
1 stop4h 39m
United Airlines
Deal found 4/2![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:35 am
TYS
- SAT
1 stop4h 35m
Southwest
Sun 5/108:30 am
SAT
- TYS
1 stop5h 45m
Southwest
Deal found 4/5![Southwest logo]()
$310
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:50 pm
TYS
- SAT
1 stop6h 25m
Southwest
Tue 4/289:40 am
SAT
- TYS
2 stops9h 00m
Southwest
Deal found 4/2![Southwest logo]()
$313
Best flights from Knoxville to San AntonioDiscover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
Discover carefully curated flight deals from Knoxville to San Antonio that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:40 pm
TYS
- SAT
1 stop6h 22m
American Airlines
Sat 6/65:35 pm
SAT
- TYS
1 stop5h 21m
American Airlines
Deal found 4/4![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
TYS
- SAT
1 stop5h 12m
Delta
Wed 5/136:50 am
SAT
- TYS
1 stop6h 43m
Delta
Deal found 4/2![Delta logo]()
$290
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:40 am
TYS
- SAT
2 stops6h 45m
Southwest
Wed 5/137:00 am
SAT
- TYS
2 stops9h 10m
Southwest
Deal found 4/2![Southwest logo]()
$295
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2912:45 pm
TYS
- SAT
1 stop5h 50m
Southwest
Fri 7/313:45 pm
SAT
- TYS
1 stop5h 45m
Southwest
Deal found 4/6![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/157:43 pm
TYS
- SAT
1 stop5h 47m
Delta
Thu 6/186:19 pm
SAT
- TYS
1 stop4h 38m
Delta
Deal found 4/2![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:35 am
TYS
- SAT
2 stops6h 50m
Southwest
Sun 5/108:30 am
SAT
- TYS
1 stop5h 45m
Southwest
Deal found 4/5![Southwest logo]()
$315
This Delta deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:40 am
TYS
- SAT
1 stop5h 12m
Delta
Sun 7/55:25 am
SAT
- TYS
1 stop4h 44m
Delta
Deal found 4/3![Delta logo]()
$341
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:45 pm
TYS
- SAT
1 stop6h 30m
Southwest
Sun 5/36:10 am
SAT
- TYS
2 stops6h 55m
Southwest
Deal found 4/6![Southwest logo]()
$334
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:35 am
TYS
- SAT
2 stops6h 50m
Southwest
Fri 5/81:25 pm
SAT
- TYS
1 stop5h 55m
Southwest
Deal found 4/6![Southwest logo]()
$334
Last-minute flights from Knoxville to San AntonioDiscover last-minute flight deals from Knoxville to San Antonio. Data last updated April 7, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to San Antonio. Data last updated April 7, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:53 pm
TYS
- SAT
1 stop6h 05m
United Airlines
Tue 4/286:02 pm
SAT
- TYS
1 stop4h 39m
United Airlines
Deal found 4/2![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/215:50 pm
TYS
- SAT
1 stop6h 25m
Southwest
Tue 4/289:40 am
SAT
- TYS
2 stops9h 00m
Southwest
Deal found 4/2![Southwest logo]()
$313
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/17:30 am
TYS
- SAT
1 stop17h 21m
Multiple Airlines
Sun 5/36:00 am
SAT
- TYS
1 stop13h 35m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/211:40 am
TYS
- SAT
1 stop5h 03m
United Airlines
Sat 5/99:50 am
SAT
- TYS
1 stop7h 21m
United Airlines
Deal found 4/5![United Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:40 am
TYS
- SAT
2 stops6h 45m
Southwest
Sat 5/99:15 am
SAT
- TYS
2 stops8h 15m
Southwest
Deal found 4/5![Southwest logo]()
$284
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:35 am
TYS
- SAT
1 stop4h 35m
Southwest
Sun 5/108:30 am
SAT
- TYS
1 stop5h 45m
Southwest
Deal found 4/5![Southwest logo]()
$310
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:40 am
TYS
- SAT
1 stop5h 12m
Delta
Wed 5/136:50 am
SAT
- TYS
1 stop6h 43m
Delta
Deal found 4/2![Delta logo]()
$290
This Southwest deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:40 am
TYS
- SAT
2 stops6h 45m
Southwest
Wed 5/137:00 am
SAT
- TYS
2 stops9h 10m
Southwest
Deal found 4/2![Southwest logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/911:56 am
TYS
- SAT
1 stop29h 20m
Multiple Airlines
Fri 5/155:26 pm
SAT
- TYS
1 stop16h 40m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$298
One-way flights from Knoxville to San AntonioSearch for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
Search for one-way flight options from Knoxville to San Antonio. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/96:54 pm
TYS
- SAT
1 stop4h 58m
American Airlines
Deal found 4/2![American Airlines logo]()
$129
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/97:00 am
TYS
- SAT
2 stops9h 43m
United Airlines
Deal found 4/2![United Airlines logo]()
$134
This United Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/195:55 pm
TYS
- SAT
1 stop5h 59m
United Airlines
Deal found 4/4![United Airlines logo]()
$148
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:33 pm
TYS
- SAT
1 stop6h 11m
Delta
Deal found 4/2![Delta logo]()
$152
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/311:27 am
TYS
- SAT
3 stops56h 32m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$156
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/271:15 pm
TYS
- SAT
3 stops51h 38m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$157
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/116:20 pm
TYS
- SAT
3 stops49h 39m
Multiple Airlines
Deal found 4/2![Multiple Airlines logo]()
$159
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:55 pm
TYS
- SAT
2 stops7h 50m
Southwest
Deal found 4/5![Southwest logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/109:40 pm
TYS
- SAT
1 stop19h 36m
Multiple Airlines
Deal found 4/5![Multiple Airlines logo]()
$164
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/13:58 pm
TYS
- SAT
1 stop8h 01m
American Airlines
Deal found 4/4![American Airlines logo]()
$165
This Southwest deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/16:35 am
TYS
- SAT
2 stops7h 40m
Southwest
Deal found 4/4![Southwest logo]()
$170
Find flight deals from Knoxville to San Antonio
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $274 (American Airlines) |
One-way from | $129 (American Airlines) |
Popular in | June |
Cheapest in | July |
Average price | $332 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from Knoxville to San Antonio that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Wed 6/3
3:40 pm-9:02 pm
1 stop6h 22m
San Antonio
Sat 6/6
5:35 pm-11:56 pm
1 stop5h 21m
$274
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 5/9
5:40 am-9:52 am
1 stop5h 12m
San Antonio
Wed 5/13
6:50 am-2:33 pm
1 stop6h 43m
$290
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 5/9
6:40 am-12:25 pm
2 stops6h 45m
San Antonio
Wed 5/13
7:00 am-5:10 pm
2 stops9h 10m
$295
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Wed 7/29
12:45 pm-5:35 pm
1 stop5h 50m
San Antonio
Fri 7/31
3:45 pm-10:30 pm
1 stop5h 45m
$315
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Thu 5/7
6:35 am-12:25 pm
2 stops6h 50m
San Antonio
Sun 5/10
8:30 am-3:15 pm
1 stop5h 45m
$315
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Fri 5/1
6:45 pm-12:15 am
1 stop6h 30m
San Antonio
Sun 5/3
6:10 am-2:05 pm
2 stops6h 55m
$334
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Fri 5/8
6:35 am-12:25 pm
2 stops6h 50m
San Antonio
Fri 5/8
1:25 pm-8:20 pm
1 stop5h 55m
$334
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Mon 6/15
7:43 pm-12:30 am
1 stop5h 47m
San Antonio
Thu 6/18
6:19 pm-11:57 pm
1 stop4h 38m
$341
Quickest round-trip
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Thu 7/2
5:40 am-9:52 am
1 stop5h 12m
San Antonio
Sun 7/5
5:25 am-11:09 am
1 stop4h 44m
$341
Cheapest one-way
Quickest one-way
KnoxvilleSan Antonio
TYS - SAT
TYSSAT
Knoxville McGhee Tyson
Sat 5/9
6:54 pm-10:52 pm
1 stop4h 58m
$129
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Knoxville to San Antonio
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to San Antonio in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-San Antonio flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-San Antonio flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-San Antonio flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-San Antonio flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-San Antonio flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to San Antonio
Have a flexible travel schedule? Discover the best time to fly to San Antonio from Knoxville with our price prediction graph.
TYS-SAT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to San Antonio
How far ahead should I book a flight from Knoxville to San Antonio?
Use this chart to determine the optimal time to book a round-trip flight from Knoxville to San Antonio. Price data was last updated on April 3, 2026.
To ensure you get the cheapest price possible for a flight from Knoxville to San Antonio, you should look to book at least 7 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Knoxville to San Antonio?
Currently, May is the cheapest month in which you can book a flight from Knoxville to San Antonio (average of $86). Flying from Knoxville to San Antonio in February is currently the most expensive (average of $238). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Knoxville to San Antonio?
Reviews of airlines servicing San Antonio
Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated April 7, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Knoxville to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Entertainment
7.5
Crew
8.6
Reviews
1 / 20
2.0
MediocreMike,Aug 2025
OKC - AUS
Related info for your journey
Find useful and relevant information for your journey from Knoxville to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Antonio?
Book flights to San Antonio if you plan to visit one of these locationsNew Braunfels
Kerrville
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Knoxville and San Antonio flights
Browse other Knoxville and San Antonio flight options. Last updated on April 7, 2026.
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Top 4 airlines flying from Knoxville to San Antonio
Discover the top 4 airlines that operate flights from Knoxville to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$207 | Average$308 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$512 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$232 | Average$334 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$236 | Average$362 | FlexibilityNo cancel fee | On-time69% |