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$117+ Cheap flights from Des Moines to San Antonio (DSM - SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/28. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Aug 2 — Aug 91
Sat 8/2
Sat 8/9
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to San Antonio are usually found in August or July, booked 58 days in advance, depart on a Wednesday or Thursday and return on a Tuesday

Cheap flight deals from Des Moines to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 28, 2025.

Round-trip from

$225
(FlightHub)

One-way from

$117
(FlightHub)

Popular in

June

Cheapest in

August

Average price

$335
From Des Moines to San Antonio
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One-way flight from Des Moines to San Antonio
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Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to San Antonio

Cheapest flights from Des Moines to San Antonio
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 28, 2025.

This FlightHub deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/52:25 pmDSM - SAT
1 stop24h 02mFrontier
Sun 9/79:55 amSAT - DSM
1 stop27h 45mFrontier
Deal found 7/27$225
This American Airlines deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3011:15 amDSM - SAT
1 stop8h 10mAmerican Airlines
Tue 11/49:14 amSAT - DSM
1 stop5h 42mAmerican Airlines
Deal found 7/26$237
This Delta deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/302:12 pmDSM - SAT
1 stop6h 47mDelta
Tue 9/26:25 amSAT - DSM
1 stop7h 44mDelta
Deal found 7/27$288
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/33:25 pmDSM - SAT
2 stops7h 23mUnited Airlines
Thu 9/45:58 pmSAT - DSM
1 stop4h 30mUnited Airlines
Deal found 7/28$307
This Southwest deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:35 amDSM - SAT
2 stops7h 40mSouthwest
Tue 11/42:35 pmSAT - DSM
2 stops7h 00mSouthwest
Deal found 7/26$312
This Mytrip deal was found by Cheapflights users on 7/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/73:44 pmDSM - SAT
2 stops21h 22mMultiple Airlines
Sun 8/105:38 pmSAT - DSM
1 stop5h 00mMultiple Airlines
Deal found 7/26$331

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2025.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.

Fly from

Des Moines

Fly to

San Antonio

Route

Depart

Return

Price

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 9/5

2:25 pm-2:27 pm

1 stop24h 02m

San Antonio

Sun 9/7

9:55 am-1:40 pm

1 stop27h 45m

$225

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 8/30

2:12 pm-8:59 pm

1 stop6h 47m

San Antonio

Tue 9/2

6:25 am-2:09 pm

1 stop7h 44m

$288

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Wed 8/27

9:28 am-2:11 pm

1 stop4h 43m

San Antonio

Mon 9/1

8:00 am-3:01 pm

1 stop7h 01m

$302

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Wed 9/3

3:25 pm-10:48 pm

2 stops7h 23m

San Antonio

Thu 9/4

5:58 pm-10:28 pm

1 stop4h 30m

$307

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Thu 8/7

3:44 pm-1:06 pm

2 stops21h 22m

San Antonio

Sun 8/10

5:38 pm-10:38 pm

1 stop5h 00m

$331

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 8/30

6:10 am-11:00 am

1 stop4h 50m

San Antonio

Mon 9/1

5:35 am-1:00 pm

2 stops7h 25m

$337

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Thu 8/28

3:23 pm-7:33 pm

1 stop28h 10m

$117

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Thu 8/28

7:00 am-1:53 pm

2 stops30h 53m

$202

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 8/2

11:59 am-6:02 pm

1 stop6h 03m

$318

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 8/2

6:00 am-1:19 pm

2 stops7h 19m

$323

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/26

Showing 1-10 of 11 results
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Best time to book a flight from Des Moines to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to San Antonio

How far ahead should I book a flight from Des Moines to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to San Antonio. Price data was last updated on July 25, 2025.

The price you pay for your flight from Des Moines to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $295). Flying from Des Moines to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SAT?

Find hourly flight availability from Des Moines to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 28, 2025.

One of the essential ways to save on airfare from Des Moines to San Antonio is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated July 28, 2025.
Read reviews from past customers who have flown Southwest, Delta, and United Airlines from Des Moines to San Antonio. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,237 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,237 reviews
Southwest
8.0
Very good
4,237 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,971 reviews
Southwest
8.0
Very good
4,237 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,893 reviews
Southwest
8.0
Very good
4,237 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,237 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Frontier
5.9
Fair
3,238 reviews
Southwest
8.0
Very good
4,237 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Crew

8.6

Boarding

8.1

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to San Antonio round-trip?

    Currently priced at $225, Frontier will fly you from Des Moines to San Antonio and back. In addition to Frontier, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from Delta and American Airlines - these airlines can fly you to your destination from $288 and $302, respectively. These flights start at 41% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to San Antonio one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $117. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Des Moines to San Antonio for a low price.

  • Can I find deals for flights from Des Moines to San Antonio that include hotel bookings?

    Yes. In addition to deals on Des Moines to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to San Antonio.

  • Can I find deals for business class flights from Des Moines to San Antonio?

    Yes. Cheapflights offers flight deals from Des Moines to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $295). Flying from Des Moines to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
New Braunfels

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Alternative routes for Des Moines to San Antonio

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Des Moines to San Antonio

Discover the top 4 airlines that operate flights from Des Moines to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$286Average$398FlexibilityNo cancel feeOn-time71%
DeltaCheapest$289Average$366FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$296Average$451FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$327Average$386FlexibilityNo cancel feeOn-time63%

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