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$137+ Cheap flights from Des Moines to San Antonio (DSM - SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — SAT
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to San Antonio are usually found in August or July, booked 27 days in advance, depart on a Wednesday or Thursday and return on a Tuesday

Cheap flight deals from Des Moines to San Antonio

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to San Antonio (SAT). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$226
(Mytrip)

One-way from

$137
(Mytrip)

Popular in

June

Cheapest in

August

Average price

$481
From Des Moines to San Antonio
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One-way flight from Des Moines to San Antonio
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Highest demand for flights based on searches. 1% potential increase in price ($5 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to San Antonio

Cheapest flights from Des Moines to San Antonio
Explore the most affordable flight options available from Des Moines to San Antonio. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/237:30 amDSM - SAT
1 stop11h 06mMultiple Airlines
Wed 7/307:52 pmSAT - DSM
1 stop26h 44mMultiple Airlines
Deal found 6/10$226
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/305:19 amDSM - SAT
1 stop4h 01mAmerican Airlines
Tue 11/46:40 pmSAT - DSM
1 stop4h 00mAmerican Airlines
Deal found 6/11$271
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/295:30 amDSM - SAT
1 stop8h 24mDelta
Mon 8/45:25 amSAT - DSM
1 stop8h 14mDelta
Deal found 6/10$284
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/293:25 pmDSM - SAT
2 stops7h 23mUnited Airlines
Tue 9/26:48 amSAT - DSM
1 stop5h 35mUnited Airlines
Deal found 6/12$306
This Booking.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/38:41 pmDSM - SAT
1 stop17h 19mFrontier
Sun 10/58:26 pmSAT - DSM
1 stop23h 30mFrontier
Deal found 6/10$316
This Southwest deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/316:25 amDSM - SAT
2 stops11h 05mSouthwest
Tue 11/42:35 pmSAT - DSM
2 stops7h 00mSouthwest
Deal found 6/11$355

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to San Antonio that are best for you.

Fly from

Des Moines

Fly to

San Antonio

Route

Depart

Return

Price

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Wed 7/23

7:30 am-6:36 pm

1 stop11h 06m

San Antonio

Wed 7/30

7:52 pm-10:36 pm

1 stop26h 44m

$226

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Tue 7/29

5:30 am-1:54 pm

1 stop8h 24m

San Antonio

Mon 8/4

5:25 am-1:39 pm

1 stop8h 14m

$284

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Sat 7/26

6:03 pm-11:59 pm

1 stop5h 56m

San Antonio

Sat 8/2

7:35 pm-11:49 pm

1 stop4h 14m

$295

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 8/29

3:25 pm-10:48 pm

2 stops7h 23m

San Antonio

Tue 9/2

6:48 am-12:23 pm

1 stop5h 35m

$306

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Tue 7/29

5:25 am-12:50 pm

1 stop7h 25m

San Antonio

Mon 8/4

3:30 pm-11:50 pm

2 stops8h 20m

$360

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 7/11

2:00 pm-10:08 am

2 stops20h 08m

$137

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 7/25

7:32 pm-11:58 pm

1 stop4h 26m

$184

Des MoinesSan Antonio

DSM - SAT

DSMSAT

Des Moines

Fri 7/25

11:25 am-11:59 pm

2 stops12h 34m

$375

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from Des Moines to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to San Antonio

How far ahead should I book a flight from Des Moines to San Antonio?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to San Antonio. Price data was last updated on June 9, 2025.

The price you pay for your flight from Des Moines to San Antonio may vary depending on when you book. For the best chance of a lower fare, look to book 27 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Des Moines to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $295). Flying from Des Moines to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to SAT?

Find hourly flight availability from Des Moines to San Antonio. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

One of the essential ways to save on airfare from Des Moines to San Antonio is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 26% on airfare.

What is the cheapest day to fly from Des Moines to San Antonio?

Use this chart to determine the cheapest time to fly round-trip from Des Moines to San Antonio. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Des Moines to San Antonio flight should consider departing on Monday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in San Antonio by month

Plan your trip to San Antonio by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in San Antonio ranges from 1.6 - 3.7 inches per month. May is typically the wettest month, when rainfall can reach 3.7 in. December is typically the driest time to visit San Antonio when rainfall is around 1.6 in.

Temperature in San Antonio by month

Plan your trip to San Antonio by taking into account the average temperature totals by month.

If weather is an important factor for your trip to San Antonio, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 51.8 F).

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated June 12, 2025.
Get a feel of what it's like to fly with Southwest, Delta and United Airlines from Des Moines to San Antonio by reading reviews from past customers. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Southwest
8.0
Very good
4,287 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
Delta
8.0
Very good
7,946 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
United Airlines
7.4
Good
8,790 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,287 reviews

Food

7.1

Entertainment

7.6

Boarding

8.2

Overall

8.0

Comfort

8.0

Crew

8.6

Reviews

1 / 20
8.0
Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to San Antonio round-trip?

    Currently priced at $284, Delta will fly you from Des Moines to San Antonio and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $295 and $306, respectively. These flights start at 26% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to San Antonio that include hotel bookings?

    Yes. In addition to deals on Des Moines to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to San Antonio.

  • Can I find deals for business class flights from Des Moines to San Antonio?

    Yes. Cheapflights offers flight deals from Des Moines to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Des Moines to San Antonio (average of $295). Flying from Des Moines to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Des Moines?

Book flights to Des Moines if you plan to visit one of these locations
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Alternative routes for Des Moines to San Antonio

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Top 5 airlines flying from Des Moines to San Antonio

Discover the top 5 airlines that operate flights from Des Moines to San Antonio. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$111Average$201FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$285Average$392FlexibilityNo cancel feeOn-time71%
DeltaCheapest$289Average$365FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$302Average$456FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$327Average$386FlexibilityNo cancel feeOn-time63%

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