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$397+ Cheap flights from Florence, SC to San Antonio (FLO - SAT)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — SAT
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Find flight deals from Florence to San Antonio

One-way flights from Florence to San Antonio
Search for one-way flight options from Florence to San Antonio. Find affordable one-way fares based on user searches. Data last updated July 3, 2025.

This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/86:20 amFLO - SAT
1 stop4h 49mAmerican Airlines
Deal found 7/1$397

Cheapflights Fare Finder

Customize your flight search to find flights from Florence to San Antonio that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Florence to San Antonio that are best for you.

Fly from

Florence

Fly to

San Antonio

Route

Depart

Return

Price

FlorenceSan Antonio

FLO - SAT

FLOSAT

Florence

Fri 8/8

6:20 am-10:09 am

1 stop4h 49m

$397

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/1

Best time to book a flight from Florence to San Antonio

Have a flexible travel schedule? Discover the best time to fly to San Antonio from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to San Antonio

What is the cheapest month to book a flight from Florence, South Carolina to San Antonio?

Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to San Antonio (average of $295). Flying from Florence, South Carolina to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing San Antonio

Get insights into the airlines that provide service to San Antonio. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Antonio. Reviews last updated July 3, 2025.
Peruse reviews from past customers who have flown with American Airlines from Florence to San Antonio to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Food

6.5

Crew

8.0

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Boarding

7.5

Food

6.5

Crew

8.0

Comfort

7.2

Entertainment

6.9

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Anonymous,Jan 2025

PIT - DFW

Due to gate changes,we nearly missed our flight. The gate agent reassigned our seats and would NOT give us our assigned seats,but she did honor that same request to the man who arrived after us. Her rudeness and difficulty was not appropriate.

Related info for your journey

Find useful and relevant information for your journey from Florence to San Antonio. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • Can I find deals for flights from Florence to San Antonio that include hotel bookings?

    Yes. In addition to deals on Florence to San Antonio flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to San Antonio?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to San Antonio.

  • Can I find deals for business class flights from Florence to San Antonio?

    Yes. Cheapflights offers flight deals from Florence to San Antonio by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to San Antonio?

    Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to San Antonio (average of $295). Flying from Florence, South Carolina to San Antonio in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Florence?

Book flights to Florence if you plan to visit one of these locations
New Braunfels

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