Roanoke

$289+ Cheap flights from Mesa, AZ to Roanoke (ROA)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — ROA
Dec 3 — Dec 101
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mesa to Roanoke with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mesa to Roanoke

Keep the following information in mind while searching for Mesa to Roanoke flight deals. Data was last updated November 3, 2025.

Round-trip from

$289
(American Airlines)

Popular in

January

Cheapest in

August

Average price

$513
From Mesa to Roanoke
Highest demand for flights based on searches. 20% potential increase in price ($129 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($28 potential savings vs. average RT price).
Average for round-trip flights in November 2025

Find flight deals from Mesa to Roanoke

Cheapest flights from Mesa to Roanoke
Explore the most affordable flight options available from Mesa to Roanoke. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 3, 2025.

This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:59 pmPHX - ROA
1 stop8h 41mDelta
Mon 12/86:00 amROA - PHX
1 stop8h 13mDelta
Deal found 11/3$289
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1711:59 pmPHX - ROA
1 stop8h 41mDelta
Thu 1/16:00 amROA - PHX
1 stop6h 40mDelta
Deal found 11/2$314
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/222:37 pmPHX - ROA
1 stop7h 34mDelta
Fri 11/286:00 amROA - PHX
1 stop8h 13mDelta
Deal found 11/2$359
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1612:30 amPHX - ROA
1 stop7h 14mAmerican Airlines
Thu 1/17:00 amROA - PHX
1 stop7h 06mAmerican Airlines
Deal found 11/2$381
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:35 amPHX - ROA
2 stops12h 10mUnited Airlines
Mon 12/82:55 pmROA - PHX
1 stop8h 10mUnited Airlines
Deal found 11/3$384
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/212:30 amPHX - ROA
1 stop7h 14mAmerican Airlines
Mon 12/82:03 pmROA - PHX
2 stops9h 12mAmerican Airlines
Deal found 11/3$386
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1212:30 amPHX - ROA
1 stop8h 01mAmerican Airlines
Tue 11/1812:43 pmROA - PHX
1 stop7h 21mAmerican Airlines
Deal found 11/2$404
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/3011:59 pmPHX - ROA
1 stop7h 48mUnited Airlines
Sun 12/710:20 amROA - PHX
1 stop7h 22mUnited Airlines
Deal found 11/2$405
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1312:39 pmPHX - ROA
1 stop6h 29mUnited Airlines
Tue 11/183:00 pmROA - PHX
2 stops9h 41mUnited Airlines
Deal found 11/2$409
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:30 pmPHX - ROA
2 stops12h 27mUnited Airlines
Thu 1/15:42 pmROA - PHX
1 stop8h 35mUnited Airlines
Deal found 11/3$419

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mesa to Roanoke that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
Use the filters below to find and compare flights from Mesa to Roanoke that are best for you.

Fly from

Mesa

Fly to

Roanoke

Route

Depart

Return

Price

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Fri 12/5

2:37 pm-12:11 am

1 stop7h 34m

Roanoke

Mon 12/8

6:00 am-12:13 pm

1 stop8h 13m

$289

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Fri 1/16

12:30 am-9:41 am

1 stop7h 11m

Roanoke

Sun 1/18

1:56 pm-6:54 pm

1 stop6h 58m

$289

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Wed 12/3

11:59 pm-10:40 am

1 stop8h 41m

Roanoke

Mon 12/8

6:00 am-12:13 pm

1 stop8h 13m

$289

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Wed 12/17

11:59 pm-10:40 am

1 stop8h 41m

Roanoke

Thu 1/1

6:00 am-10:40 am

1 stop6h 40m

$314

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Sat 1/17

11:53 pm-10:44 am

1 stop8h 51m

Roanoke

Sun 1/18

4:35 pm-11:43 pm

1 stop9h 08m

$354

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Sat 11/22

2:37 pm-12:11 am

1 stop7h 34m

Roanoke

Fri 11/28

6:00 am-12:13 pm

1 stop8h 13m

$359

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Tue 12/16

12:30 am-9:44 am

1 stop7h 14m

Roanoke

Mon 1/5

5:00 am-12:06 pm

1 stop9h 06m

$381

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Thu 12/4

12:30 am-9:44 am

1 stop7h 14m

Roanoke

Mon 12/8

10:09 am-5:09 pm

1 stop9h 00m

$381

PhoenixRoanoke

PHX - ROA

PHXROA

Phoenix Sky Harbor Intl

Tue 12/16

12:30 am-9:44 am

1 stop7h 14m

Roanoke

Thu 1/1

7:00 am-12:06 pm

1 stop7h 06m

$381

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/3

Best time to book a flight from Mesa to Roanoke

Have a flexible travel schedule? Discover the best time to fly to Roanoke from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to Roanoke

What is the cheapest month to book a flight from Mesa to Roanoke?

Currently, February is the cheapest month in which you can book a flight from Mesa to Roanoke (average of $255). Flying from Mesa to Roanoke in April is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to ROA?

Find hourly flight availability from Mesa to Roanoke. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 3, 2025.

One of the essential ways to save on airfare from Mesa to Roanoke is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 47% on airfare.

Reviews of airlines servicing Roanoke

Get insights into the airlines that provide service to Roanoke. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Roanoke. Reviews last updated November 3, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Mesa to Roanoke to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Food

7.3

Overall

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Mesa to Roanoke. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly into for flights to Roanoke from Mesa?

    If you book a flight to Roanoke from Mesa, you will be flying to Roanoke, which is the city’s only airport. Roanoke (ROA) is located 4.2 mi from the center of Roanoke. There are 0 flights from Mesa to Roanoke per day from 3 different airlines.

  • How long is the flight from Mesa to Roanoke?

    Delta and American Airlines can get you from Mesa to Roanoke in just under 7h 11m. Your travel time can differ by up to 23m. The distance from Mesa to Roanoke is about 1814 mi. This flight may include one or multiple stops.

  • Can I find deals for flights from Mesa to Roanoke that include hotel bookings?

    Yes. In addition to deals on Mesa to Roanoke flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to Roanoke?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to Roanoke.

  • Can I find deals for business class flights from Mesa to Roanoke?

    Yes. Cheapflights offers flight deals from Mesa to Roanoke by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to Roanoke?

    Currently, February is the cheapest month in which you can book a flight from Mesa to Roanoke (average of $255). Flying from Mesa to Roanoke in April is currently the most expensive (average of $325). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Roanoke?

Book flights to Roanoke if you plan to visit one of these locations
Radford
Salem
Blacksburg
Christiansburg

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 3 airlines flying from Mesa to Roanoke

Discover the top 3 airlines that operate flights from Mesa to Roanoke. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$256Average$413FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$288Average$510FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$288Average$477FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.