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$268+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
feb. 20 — feb. 271
vie. 2/20
vie. 2/27
1 adult, Economy
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Cheap flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on enero 21, 2026.

This oojo deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 4/2912:11 pm
STL
-
PRG
2 stops20h 34m
British Airways
vie. 5/810:10 am
PRG
-
STL
2 stops19h 04m
British Airways
Deal found 1/19$445
This oojo deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 3/21:58 pm
MCI
-
PRG
2 stops20h 32m
British Airways
mar. 3/3110:25 am
PRG
-
MCI
2 stops20h 29m
British Airways
Deal found 1/20$445
This British Airways deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/269:40 pm
STL
-
PRG
1 stop15h 30m
British Airways
mar. 5/59:15 pm
PRG
-
STL
2 stops31h 59m
British Airways
Deal found 1/21$457
This British Airways deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/2712:11 pm
STL
-
PRG
2 stops18h 04m
British Airways
mié. 5/66:30 am
PRG
-
STL
2 stops24h 18m
British Airways
Deal found 1/21$462
This KAYAK deal was found by Cheapflights users on 1/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/1911:05 am
MCI
-
PRG
2 stops24h 35m
British Airways
jue. 4/307:05 am
PRG
-
MCI
2 stops33h 44m
British Airways
Deal found 1/20$482
This Finnair deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 3/59:35 am
STL
-
PRG
2 stops26h 15m
Multiple Airlines
jue. 3/127:35 pm
PRG
-
STL
2 stops43h 20m
Multiple Airlines
Deal found 1/19$486
This Finnair deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 3/47:05 am
MCI
-
PRG
2 stops28h 45m
Multiple Airlines
dom. 3/87:35 pm
PRG
-
MCI
2 stops35h 04m
Multiple Airlines
Deal found 1/21$486
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 4/279:10 am
STL
-
PRG
2 stops16h 45m
United Airlines
vie. 5/86:00 am
PRG
-
STL
1 stop14h 25m
United Airlines
Deal found 1/19$490
This oojo deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/1212:11 pm
STL
-
PRG
2 stops18h 24m
British Airways
sáb. 4/185:45 pm
PRG
-
STL
1 stop32h 45m
British Airways
Deal found 1/19$492
This oojo deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/1912:11 pm
STL
-
PRG
2 stops18h 24m
British Airways
dom. 4/266:50 am
PRG
-
STL
2 stops22h 24m
British Airways
Deal found 1/19$495
This United Airlines deal was found by Cheapflights users on 1/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/129:10 am
STL
-
PRG
2 stops18h 25m
United Airlines
mar. 4/211:25 pm
PRG
-
STL
2 stops14h 43m
United Airlines
Deal found 1/19$497
This Air Canada deal was found by Cheapflights users on 1/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 4/264:05 pm
STL
-
PRG
2 stops13h 40m
Air Canada
lun. 5/119:30 am
PRG
-
STL
2 stops41h 34m
Air Canada
Deal found 1/21$499

Find flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated enero 21, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

Expedia
3 stars

Round-trip from

$445
(oojo)

One-way from

$268
(United Airlines)

Popular in

May

Cheapest in

April
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Václav Havel Prague
Search Deals
One-way flight from Missouri to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($188 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($43 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

mar. 4/28

9:35 pm-11:25 pm

1 stop18h 50m

Václav Havel Prague

mar. 5/5

9:15 pm-11:48 pm

2 stops33h 33m

$457

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

mar. 4/28

9:35 pm-11:25 pm

1 stop18h 50m

Václav Havel Prague

vie. 5/8

10:10 am-10:14 pm

2 stops19h 04m

$457

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

dom. 4/26

9:40 pm-11:15 pm

1 stop18h 35m

Václav Havel Prague

jue. 5/7

9:35 pm-10:14 pm

2 stops31h 39m

$457

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

lun. 4/27

12:11 pm-1:15 pm

2 stops18h 04m

Václav Havel Prague

mié. 5/6

6:30 am-10:14 pm

2 stops22h 44m

$462

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

dom. 4/26

12:11 pm-5:05 pm

2 stops21h 54m

Václav Havel Prague

vie. 5/8

10:10 am-10:14 pm

2 stops19h 04m

$462

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

mié. 4/29

2:29 pm-3:45 pm

2 stops18h 16m

Václav Havel Prague

lun. 5/11

8:55 pm-10:14 pm

2 stops32h 19m

$462

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

lun. 4/27

12:11 pm-1:15 pm

2 stops18h 04m

Václav Havel Prague

mar. 5/5

6:35 am-11:04 pm

2 stops23h 29m

$462

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

mié. 4/29

2:29 pm-5:05 pm

2 stops19h 36m

Václav Havel Prague

jue. 5/7

7:05 am-10:14 pm

2 stops22h 09m

$462

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mié. 3/4

8:00 am-4:05 pm

2 stops25h 05m

Václav Havel Prague

dom. 3/8

7:25 am-7:41 pm

2 stops19h 16m

$500

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

jue. 4/23

2:38 pm-8:10 pm

2 stops22h 32m

Václav Havel Prague

mar. 4/28

6:35 am-9:49 am

2 stops34h 14m

$532

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/20

Showing 1-10 of 27 results
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Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    British Airways and United Airlines can get you from Missouri to Prague in just under 18h 50m. Your travel time can differ by up to 6h 15m. The distance from Missouri to Prague is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Prague

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Prague

Discover the top 5 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated enero 21, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$383Average$797FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$548Average$959FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$556Average$854FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$742FlexibilityNo cancel feeOn-time70%
DeltaCheapest$608Average$1,217FlexibilityNo cancel feeOn-timeN/A

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