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$452+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheap flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This oojo deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3112:16 pmMCI - PRG
2 stops17h 59mBritish Airways
mié. 1/1411:00 amPRG - MCI
2 stops19h 12mBritish Airways
Deal found 12/11$694
This FlightHub deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3111:24 amMCI - PRG
3 stops18h 41mAir Canada
mié. 1/147:30 amPRG - MCI
3 stops21h 29mAir Canada
Deal found 12/11$806
This Ovago deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:35 pmSTL - PRG
2 stops20h 50mLufthansa
mié. 1/73:10 pmPRG - STL
2 stops39h 49mLufthansa
Deal found 12/11$1,259
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/261:05 pmSTL - PRG
2 stops26h 20mUnited Airlines
mié. 1/73:10 pmPRG - STL
2 stops37h 03mUnited Airlines
Deal found 12/10$1,375
This Gurufare deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:35 pmSTL - PRG
2 stops32h 15mLufthansa
mié. 1/710:15 amPRG - STL
2 stops19h 43mLufthansa
Deal found 12/11$1,393
This Ovago deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/2611:05 amSTL - PRG
2 stops28h 35mMultiple Airlines
mié. 1/77:30 amPRG - STL
1 stop13h 25mMultiple Airlines
Deal found 12/10$1,419
This Expedia deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/107:00 amMCI - PRG
2 stops45h 00mAer Lingus
mié. 12/1711:40 amPRG - MCI
2 stops38h 36mAer Lingus
Deal found 12/9$1,451
This FlightHub deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1012:45 pmMCI - PRG
2 stops14h 00mLufthansa
mié. 12/1710:15 amPRG - MCI
2 stops16h 39mLufthansa
Deal found 12/9$1,647
This Brussels Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Brussels Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1012:45 pmMCI - PRG
3 stops26h 25mBrussels Airlines
mié. 12/176:50 amPRG - MCI
3 stops44h 41mBrussels Airlines
Deal found 12/9$1,770
This FlightHub deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1010:00 amMCI - PRG
3 stops20h 05mAir Canada
mié. 12/177:30 amPRG - MCI
3 stops21h 28mAir Canada
Deal found 12/9$1,851
This Ovago deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 12/206:35 pmMCI - PRG
2 stops35h 30mLufthansa
mar. 1/66:15 amPRG - MCI
2 stops20h 41mLufthansa
Deal found 12/10$2,225
This FlightHub deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/254:05 pmSTL - PRG
2 stops20h 05mMultiple Airlines
mié. 1/77:30 amPRG - STL
3 stops18h 57mMultiple Airlines
Deal found 12/10$2,323

Find flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$452
(Kiwi.com)

Popular in

May

Cheapest in

March

Average price

$822
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($276 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

vie. 1/9

3:50 pm-9:50 am

1 stop11h 00m

Václav Havel Prague

mié. 1/14

10:15 am-10:58 pm

2 stops19h 43m

$455

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mié. 2/4

12:35 pm-1:05 pm

2 stops17h 30m

Václav Havel Prague

mar. 2/10

10:30 am-7:56 pm

2 stops16h 26m

$493

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mié. 2/4

12:35 pm-1:05 pm

2 stops17h 30m

Václav Havel Prague

jue. 2/12

7:35 am-8:06 pm

2 stops19h 31m

$493

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

dom. 1/25

5:20 pm-10:50 pm

2 stops22h 30m

Václav Havel Prague

dom. 2/1

8:40 pm-9:15 pm

2 stops31h 35m

$494

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

vie. 1/9

2:54 pm-9:05 pm

2 stops23h 11m

Václav Havel Prague

mié. 1/14

6:50 am-6:14 pm

2 stops18h 24m

$495

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

vie. 1/9

3:50 pm-6:15 pm

1 stop19h 25m

Václav Havel Prague

vie. 1/23

6:15 am-3:29 pm

2 stops40h 14m

$496

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

vie. 1/30

6:40 pm-10:25 pm

2 stops20h 45m

Václav Havel Prague

mar. 2/3

7:25 am-3:15 pm

2 stops38h 50m

$505

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

jue. 2/5

11:29 am-9:35 am

2 stops15h 06m

Václav Havel Prague

mar. 2/10

10:30 am-7:56 pm

2 stops16h 26m

$505

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mar. 2/3

2:12 pm-11:40 am

2 stops14h 28m

Václav Havel Prague

jue. 2/12

11:35 am-11:54 pm

2 stops19h 19m

$507

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

lun. 2/2

8:05 am-5:05 pm

2 stops26h 00m

Václav Havel Prague

jue. 2/12

6:00 am-5:06 pm

2 stops18h 06m

$507

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/10

Showing 1-10 of 20 results
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Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PRG?

Find hourly flight availability from Missouri to Prague. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 12, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Prague in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    Lufthansa, British Airways, and United Airlines can get you from Missouri to Prague in just under 11h. Your travel time can differ by up to 11h 30m. The distance from Missouri to Prague is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Prague

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to Prague

Discover the top 6 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$383Average$797FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$556Average$888FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$742FlexibilityNo cancel feeOn-time70%
DeltaCheapest$608Average$1,208FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$711Average$959FlexibilityNo cancel feeOn-time71%
Air CanadaCheapest$745Average$1,087FlexibilityNo cancel feeOn-time67%

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