How long is the flight from Missouri to Prague?

British Airways, American Airlines, and United Airlines can get you from Missouri to Prague in just under 15h 49m. Your travel time can differ by up to 6h 16m. The distance from Missouri to Prague is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Prague ranges from 0.4 - 2.4 inches per month. June is typically the wettest month, when rainfall can reach 2.4 in. February is typically the driest time to visit Prague when rainfall is around 0.4 in.

If weather is an important factor for your trip to Prague, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

What are the most popular airlines that fly from Missouri to Prague?

The most popular airlines flying from Missouri to Prague are United Airlines, Delta and Lufthansa. Something to consider prior to booking your flight.

What is the cheapest time of day to fly from MO to PRG?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Prague as you normally would.

What airport do you fly into for flights to Prague from Missouri?

Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

Can I find deals for flights from Missouri to Prague that include hotel bookings?

Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Prague?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

Can I find deals for business class flights from Missouri to Prague?

Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$261+ Flights from Missouri to Prague

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Cheap flight deals from Missouri to Prague

Most accurate provider	eDreams 3 stars
Most trusted provider	eDreams 3 stars
Round-trip from	$407 (Ticket)
One-way from	$261 (oojo)
Popular in	May
Cheapest in	February

Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.

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Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.

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From Missouri to Václav Havel Prague

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One-way flight from Missouri to Václav Havel Prague

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Highest demand for flights based on searches. 21% potential increase in price ($248 potential increase over avg. RT price).

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Cheapest flight prices on average. 4% potential price decrease ($41 potential savings vs. average RT price).

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Find flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 11, 2026.

Wed 4/2912:11 pmSTL - PRG

2 stops20h 34mBritish Airways

Fri 5/810:10 amPRG - STL

2 stops19h 04mBritish Airways

Deal found 1/10

$445

Wed 3/412:38 pmMCI - PRG

2 stops25h 02mBritish Airways

Tue 3/1010:55 amPRG - MCI

2 stops18h 59mBritish Airways

Deal found 1/9

$482

Tue 2/248:00 amMCI - PRG

2 stops22h 05mUnited Airlines

Tue 3/31:45 pmPRG - MCI

2 stops15h 14mUnited Airlines

Deal found 1/10

$493

Sun 4/1912:11 pmSTL - PRG

2 stops18h 24mBritish Airways

Sun 4/266:50 amPRG - STL

2 stops22h 24mBritish Airways

Deal found 1/9

$495

Fri 4/2411:05 amMCI - PRG

2 stops22h 45mBritish Airways

Fri 5/810:10 amPRG - MCI

2 stops19h 40mBritish Airways

Deal found 1/9

$495

Mon 2/2312:15 pmSTL - PRG

2 stops18h 40mUnited Airlines

Mon 3/27:35 amPRG - STL

2 stops20h 30mUnited Airlines

Deal found 1/9

$497

Wed 3/41:50 pmMCI - PRG

2 stops19h 15mUnited Airlines

Sun 3/87:25 amPRG - MCI

2 stops19h 16mUnited Airlines

Deal found 1/10

$500

Tue 2/249:55 amSTL - PRG

3 stops21h 00mMultiple Airlines

Tue 3/37:25 amPRG - STL

2 stops39h 04mMultiple Airlines

Deal found 1/10

$503

Mon 4/133:21 pmMCI - PRG

2 stops39h 34mUnited Airlines

Mon 4/271:25 pmPRG - MCI

2 stops37h 23mUnited Airlines

Deal found 1/10

$506

Fri 1/165:11 pmMCI - PRG

2 stops20h 54mAmerican Airlines

Fri 1/2311:40 amPRG - MCI

2 stops17h 59mAmerican Airlines

Deal found 1/9

$507

Sat 2/75:45 amMCI - PRG

2 stops33h 40mUnited Airlines

Sat 2/147:35 amPRG - MCI

2 stops19h 31mUnited Airlines

Deal found 1/10

$509

Sat 9/57:20 pmMCI - PRG

2 stops35h 15mBritish Airways

Mon 9/218:55 pmPRG - MCI

2 stops30h 24mBritish Airways

Deal found 1/10

$512

Best flights from Missouri to Prague
Discover carefully curated flight deals from Missouri to Prague that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 11, 2026.

Wed 4/2911:44 amSTL - PRG

2 stops18h 31mBritish Airways

Fri 5/810:10 amPRG - STL

2 stops20h 38mBritish Airways

Deal found 1/9

$445

Tue 2/248:00 amMCI - PRG

2 stops22h 05mUnited Airlines

Tue 3/31:45 pmPRG - MCI

2 stops15h 14mUnited Airlines

Deal found 1/10

$493

Tue 2/249:55 amSTL - PRG

3 stops21h 00mMultiple Airlines

Tue 3/37:25 amPRG - STL

2 stops39h 04mMultiple Airlines

Deal found 1/10

$503

Sun 3/155:42 pmMCI - PRG

2 stops17h 23mDelta

Fri 3/2711:35 amPRG - MCI

2 stops27h 18mDelta

Deal found 1/9

$677

Sun 5/316:05 amMCI - PRG

1 stop19h 10mAmerican Airlines

Sun 6/78:40 amPRG - MCI

2 stops17h 09mAmerican Airlines

Deal found 1/10

$766

Wed 3/412:37 pmMCI - PRG

3 stops22h 18mBrussels Airlines

Tue 3/106:50 amPRG - MCI

2 stops19h 51mBrussels Airlines

Deal found 1/9

$850

Fri 4/2411:05 amMCI - PRG

2 stops22h 45mBritish Airways

Fri 5/810:10 amPRG - MCI

2 stops19h 40mBritish Airways

Deal found 1/9

$495

Mon 2/2312:15 pmSTL - PRG

2 stops18h 40mUnited Airlines

Mon 3/27:35 amPRG - STL

2 stops20h 30mUnited Airlines

Deal found 1/9

$497

Sat 2/1412:15 pmSTL - PRG

2 stops22h 50mMultiple Airlines

Sun 2/224:45 pmPRG - STL

2 stops37h 14mMultiple Airlines

Deal found 1/10

$543

Sun 4/199:40 pmSTL - PRG

1 stop12h 25mBritish Airways

Sun 4/266:50 amPRG - STL

2 stops23h 58mBritish Airways

Deal found 1/9

$498

Wed 3/41:50 pmMCI - PRG

2 stops19h 15mUnited Airlines

Sun 3/87:25 amPRG - MCI

2 stops19h 16mUnited Airlines

Deal found 1/10

$500

Mon 4/133:21 pmMCI - PRG

2 stops39h 34mUnited Airlines

Mon 4/271:25 pmPRG - MCI

2 stops37h 23mUnited Airlines

Deal found 1/10

$506

Sat 1/311:40 pmSTL - PRG

2 stops23h 10mBritish Airways

Sat 2/77:15 pmPRG - STL

2 stops34h 29mBritish Airways

Deal found 1/10

$545

Sat 2/75:45 amMCI - PRG

2 stops33h 40mUnited Airlines

Sat 2/147:35 amPRG - MCI

2 stops19h 31mUnited Airlines

Deal found 1/10

$509

Wed 1/216:30 amSTL - PRG

2 stops24h 25mUnited Airlines

Sun 1/256:15 amPRG - STL

2 stops23h 43mUnited Airlines

Deal found 1/10

$540

Sat 2/144:05 pmSTL - PRG

2 stops39h 10mUnited Airlines

Sun 2/223:00 pmPRG - STL

2 stops53h 14mUnited Airlines

Deal found 1/8

$546

Mon 6/226:37 pmMCI - PRG

2 stops33h 13mUnited Airlines

Wed 7/19:10 amPRG - MCI

2 stops21h 27mUnited Airlines

Deal found 1/10

$945

Last-minute flights from Missouri to Prague
Discover last-minute flight deals from Missouri to Prague. Data last updated January 11, 2026 and is based on user searches.

Fri 1/165:11 pmMCI - PRG

2 stops20h 54mAmerican Airlines

Fri 1/2311:40 amPRG - MCI

2 stops17h 59mAmerican Airlines

Deal found 1/9

$507

Sat 1/176:30 pmMCI - PRG

2 stops33h 40mLufthansa

Mon 1/264:45 pmPRG - MCI

2 stops36h 14mLufthansa

Deal found 1/9

$539

Sun 1/1811:29 amMCI - PRG

2 stops27h 56mLufthansa

Mon 1/264:45 pmPRG - MCI

2 stops36h 14mLufthansa

Deal found 1/9

$518

Mon 1/196:00 amMCI - PRG

2 stops31h 35mBritish Airways

Mon 1/262:30 pmPRG - MCI

2 stops39h 09mBritish Airways

Deal found 1/9

$535

Wed 1/216:30 amSTL - PRG

2 stops24h 25mUnited Airlines

Sun 1/256:15 amPRG - STL

2 stops23h 43mUnited Airlines

Deal found 1/10

$540

Wed 2/45:04 pmSTL - PRG

2 stops17h 26mBritish Airways

Wed 2/186:50 amPRG - STL

2 stops23h 58mBritish Airways

Deal found 1/9

$445

Sat 2/75:45 amMCI - PRG

2 stops33h 40mUnited Airlines

Sat 2/147:35 amPRG - MCI

2 stops19h 31mUnited Airlines

Deal found 1/10

$509

Sat 2/1412:15 pmSTL - PRG

2 stops22h 50mMultiple Airlines

Sun 2/224:45 pmPRG - STL

2 stops37h 14mMultiple Airlines

Deal found 1/10

$543

Mon 2/2312:15 pmSTL - PRG

2 stops18h 40mUnited Airlines

Mon 3/27:35 amPRG - STL

2 stops20h 30mUnited Airlines

Deal found 1/9

$497

Tue 2/248:00 amMCI - PRG

2 stops22h 05mUnited Airlines

Tue 3/31:45 pmPRG - MCI

2 stops15h 14mUnited Airlines

Deal found 1/10

$493

Tue 2/249:55 amSTL - PRG

3 stops21h 00mMultiple Airlines

Tue 3/37:25 amPRG - STL

2 stops39h 04mMultiple Airlines

Deal found 1/10

$503

Tue 2/2411:39 amSTL - PRG

2 stops18h 26mLufthansa

Tue 3/36:55 pmPRG - STL

1 stop26h 00mLufthansa

Deal found 1/10

$520

One-way flights from Missouri to Prague
Search for one-way flight options from Missouri to Prague. Find affordable one-way fares based on user searches. Data last updated January 11, 2026.

Sat 4/257:50 pmMCI - PRG

2 stops34h 45mBritish Airways

Deal found 1/9

$261

Fri 4/2411:05 amMCI - PRG

2 stops22h 45mBritish Airways

Deal found 1/10

$300

Fri 4/246:28 pmMCI - PRG

2 stops15h 22mAmerican Airlines

Deal found 1/9

$307

Mon 4/201:29 pmSTL - PRG

2 stops19h 36mBritish Airways

Deal found 1/9

$369

Mon 4/202:29 pmSTL - PRG

2 stops18h 36mAmerican Airlines

Deal found 1/10

$376

Sat 4/2511:30 amMCI - PRG

3 stops18h 15mAir Canada

Deal found 1/9

$622

Fri 4/2411:30 amMCI - PRG

3 stops18h 15mAir Canada

Deal found 1/9

$697

Thu 1/158:00 amMCI - PRG

2 stops22h 50mTurkish Airlines

Deal found 1/8

$4,472

Fri 1/1611:29 amMCI - PRG

2 stops24h 01mMultiple Airlines

Deal found 1/8

$4,893

Sat 1/178:00 amMCI - PRG

2 stops27h 30mTurkish Airlines

Deal found 1/8

$4,922

Mon 4/206:07 pmSTL - PRG

3 stops46h 28mMultiple Airlines

Deal found 1/9

$7,966

Sat 1/1712:35 pmMCI - PRG

3 stops22h 30mBrussels Airlines

Deal found 1/8

$8,535

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 4/29

11:44 am-1:15 pm

2 stops18h 31m

Václav Havel Prague

Fri 5/8

10:10 am-11:48 pm

2 stops20h 38m

$445

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Tue 2/24

8:00 am-1:05 pm

2 stops22h 05m

Václav Havel Prague

Tue 3/3

1:45 pm-9:59 pm

2 stops15h 14m

$493

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Fri 4/24

11:05 am-4:50 pm

2 stops22h 45m

Václav Havel Prague

Fri 5/8

10:10 am-10:50 pm

2 stops19h 40m

$495

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Mon 2/23

12:15 pm-1:55 pm

2 stops18h 40m

Václav Havel Prague

Mon 3/2

7:35 am-9:05 pm

2 stops20h 30m

$497

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 4/19

9:40 pm-5:05 pm

1 stop12h 25m

Václav Havel Prague

Sun 4/26

6:50 am-11:48 pm

2 stops23h 58m

$498

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 3/4

1:50 pm-4:05 pm

2 stops19h 15m

Václav Havel Prague

Sun 3/8

7:25 am-7:41 pm

2 stops19h 16m

$500

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Tue 2/24

9:55 am-1:55 pm

3 stops21h 00m

Václav Havel Prague

Tue 3/3

7:25 am-3:29 pm

2 stops39h 04m

$503

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Mon 4/13

3:21 pm-1:55 pm

2 stops39h 34m

Václav Havel Prague

Mon 4/27

1:25 pm-7:48 pm

2 stops37h 23m

$506

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sat 2/7

5:45 am-10:25 pm

2 stops33h 40m

Václav Havel Prague

Sat 2/14

7:35 am-8:06 pm

2 stops19h 31m

$509

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 1/21

6:30 am-1:55 pm

2 stops24h 25m

Václav Havel Prague

Sun 1/25

6:15 am-10:58 pm

2 stops23h 43m

$540

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/9

Showing 1-10 of 31 results

Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

What airport do you fly into for flights to Prague from Missouri?
Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.
How long is the flight from Missouri to Prague?
British Airways, American Airlines, and United Airlines can get you from Missouri to Prague in just under 15h 49m. Your travel time can differ by up to 6h 16m. The distance from Missouri to Prague is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Missouri to Prague that include hotel bookings?
Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Prague?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.
Can I find deals for business class flights from Missouri to Prague?
Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Prague?
Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 5 airlines flying from Missouri to Prague

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$383	Average$797	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$548	Average$959	FlexibilityNo cancel fee	On-time71%
Lufthansa	Cheapest$556	Average$947	FlexibilityNo cancel fee	On-time76%
British Airways	Cheapest$582	Average$742	FlexibilityNo cancel fee	On-time70%
Delta	Cheapest$608	Average$1,217	FlexibilityNo cancel fee	On-timeN/A

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$261+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Missouri to Prague with Cheapflights

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Cheap flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated January 11, 2026.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Find flight deals from Missouri to Prague

Cheapest flights from Missouri to PragueExplore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 11, 2026.

Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 11, 2026.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Prague from Missouri?

How long is the flight from Missouri to Prague?

Can I find deals for flights from Missouri to Prague that include hotel bookings?

How can I find direct flights from Missouri to Prague?

Can I find deals for business class flights from Missouri to Prague?

What is the cheapest month to book a flight from Missouri to Prague?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Prague

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Top 5 airlines flying from Missouri to Prague

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Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 11, 2026.