HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Prague

$371+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/14. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
Dec 26 — Jan 21
Fri 12/26
Fri 1/2
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Prague with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Find flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This oojo deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:00 pmMCI - PRG
2 stops25h 50mBritish Airways
Wed 1/146:30 pmPRG - MCI
2 stops35h 42mBritish Airways
Deal found 11/26$445
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/26:05 pmSTL - PRG
2 stops16h 00mDelta
Wed 12/106:30 amPRG - STL
2 stops22h 27mDelta
Deal found 11/25$483
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:38 pmSTL - PRG
2 stops19h 27mDelta
Thu 12/116:30 amPRG - STL
2 stops23h 59mDelta
Deal found 11/25$492
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:38 pmSTL - PRG
2 stops19h 27mDelta
Mon 12/811:35 amPRG - STL
2 stops36h 35mDelta
Deal found 11/25$493
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:39 amSTL - PRG
2 stops18h 46mDelta
Thu 12/116:30 amPRG - STL
2 stops23h 59mDelta
Deal found 11/25$495
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:45 amSTL - PRG
2 stops14h 40mDelta
Wed 12/106:30 amPRG - STL
2 stops23h 59mDelta
Deal found 11/25$496
This Cheapflightsfares deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:24 amMCI - PRG
2 stops21h 41mLufthansa
Wed 1/1410:15 amPRG - MCI
2 stops18h 44mLufthansa
Deal found 11/25$499
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:45 amSTL - PRG
2 stops14h 40mDelta
Tue 12/96:30 amPRG - STL
2 stops17h 19mDelta
Deal found 11/25$500
This KLM deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/910:41 amMCI - PRG
2 stops14h 44mMultiple Airlines
Fri 2/66:30 amPRG - MCI
2 stops17h 30mMultiple Airlines
Deal found 11/26$505
This Delta deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/310:45 amSTL - PRG
2 stops14h 40mDelta
Mon 12/82:30 pmPRG - STL
2 stops33h 05mDelta
Deal found 11/25$506
This United Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:40 pmMCI - PRG
2 stops25h 45mUnited Airlines
Mon 12/157:35 amPRG - MCI
2 stops21h 23mUnited Airlines
Deal found 11/24$818
This Air Canada deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:24 amMCI - PRG
3 stops18h 41mAir Canada
Wed 1/147:30 amPRG - MCI
3 stops21h 29mAir Canada
Deal found 11/26$1,093

Cheap flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$443
(Flysmarter)

One-way from

$371
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$754
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Václav Havel Prague
Search Deals
One-way flight from Missouri to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($304 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 1/14

9:57 am-9:05 am

2 stops16h 08m

Václav Havel Prague

Thu 1/22

6:30 am-7:19 pm

2 stops19h 49m

$484

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Mon 1/12

9:57 am-11:40 am

2 stops18h 43m

Václav Havel Prague

Thu 1/22

6:30 am-7:19 pm

2 stops19h 49m

$485

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/11

6:30 pm-4:05 pm

2 stops14h 35m

Václav Havel Prague

Tue 1/20

10:30 am-9:59 pm

2 stops18h 29m

$491

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Tue 12/2

2:38 pm-5:05 pm

2 stops19h 27m

Václav Havel Prague

Tue 12/9

6:30 am-6:33 pm

2 stops19h 03m

$492

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Mon 1/12

9:57 am-11:40 am

2 stops18h 43m

Václav Havel Prague

Tue 1/20

6:30 am-7:19 pm

2 stops19h 49m

$492

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 12/3

6:39 am-8:25 am

2 stops18h 46m

Václav Havel Prague

Thu 12/11

6:30 am-11:29 pm

2 stops23h 59m

$495

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 12/3

10:45 am-8:25 am

2 stops14h 40m

Václav Havel Prague

Tue 12/9

6:30 am-11:29 pm

2 stops23h 59m

$496

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 12/3

10:45 am-8:25 am

2 stops14h 40m

Václav Havel Prague

Wed 12/10

6:30 am-11:29 pm

2 stops23h 59m

$496

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 1/14

11:29 am-4:05 pm

2 stops21h 36m

Václav Havel Prague

Tue 1/20

7:25 am-7:56 pm

2 stops19h 31m

$497

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Mon 1/12

3:24 pm-1:05 pm

2 stops14h 41m

Václav Havel Prague

Fri 1/23

7:35 am-10:32 am

2 stops33h 57m

$497

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/23

Showing 1-10 of 20 results
1
2

Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $351). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PRG?

Find hourly flight availability from Missouri to Prague. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Prague in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Missouri to Prague?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    Delta and Lufthansa can get you from Missouri to Prague in just under 14h 35m. Your travel time can differ by up to 1h 33m. The distance from Missouri to Prague is about 4907 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $351). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Prague

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Prague flights
Newark to Prague flights
LaGuardia to Prague flights
Boston to Prague flights
Los Angeles to Prague flights
O'Hare Intl to Prague flights
Dulles Intl to Prague flights
Reagan-National to Prague flights
Seattle to Prague flights
Baltimore to Prague flights
San Francisco to Prague flights
Miami to Prague flights
Dallas/Fort Worth to Prague flights
Denver to Prague flights
Raleigh to Prague flights
Charlotte to Prague flights
Midway to Prague flights
Ontario to Prague flights
Santa Ana to Prague flights
Atlanta to Prague flights
San Jose to Prague flights
Philadelphia to Prague flights
Detroit to Prague flights
Orlando to Prague flights
Hobby to Prague flights
Love Field to Prague flights
George Bush Intcntl to Prague flights
Fort Lauderdale to Prague flights
Minneapolis to Prague flights
San Diego to Prague flights
Kansas City to Prague flights
Sky Harbor Intl to Prague flights
Portland to Prague flights
Tampa to Prague flights
Austin to Prague flights
Cleveland to Prague flights
Oakland to Prague flights
Omaha to Prague flights
Des Moines to Prague flights
Nashville to Prague flights
Jacksonville to Prague flights
Pittsburgh to Prague flights
Burbank to Prague flights
Salt Lake City to Prague flights
Las Vegas to Prague flights
West Palm Beach to Prague flights
St. Louis to Prague flights
Rochester to Prague flights
Indianapolis to Prague flights
Pensacola to Prague flights

Top 7 airlines flying from Missouri to Prague

Discover the top 7 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$383Average$818FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$571Average$968FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$758FlexibilityNo cancel feeOn-time70%
DeltaCheapest$616Average$1,188FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$711Average$959FlexibilityNo cancel feeOn-time71%
KLMCheapest$731Average$1,303FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$745Average$1,087FlexibilityNo cancel feeOn-time67%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.