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$304+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/16. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
ene. 3 — ene. 101
sáb. 1/3
sáb. 1/10
1 adult, Economy
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Cheap flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 4, 2025.

This oojo deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/312:00 pmMCI - PRG
2 stops23h 40mBritish Airways
mié. 1/149:30 pmPRG - MCI
2 stops30h 36mBritish Airways
Deal found 12/3$444
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/91:40 pmMCI - PRG
2 stops38h 25mUnited Airlines
vie. 2/66:15 amPRG - MCI
2 stops22h 44mUnited Airlines
Deal found 12/2$604
This United Airlines deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/319:00 amMCI - PRG
2 stops24h 05mUnited Airlines
jue. 1/811:50 amPRG - MCI
2 stops53h 42mUnited Airlines
Deal found 12/3$708
This Ovago deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:35 pmMCI - PRG
2 stops32h 10mLufthansa
vie. 1/910:20 amPRG - MCI
2 stops18h 39mLufthansa
Deal found 12/3$807
This FlightHub deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/3111:24 amMCI - PRG
3 stops18h 41mAir Canada
mié. 1/147:30 amPRG - MCI
3 stops21h 29mAir Canada
Deal found 12/2$1,000
This Ovago deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:35 pmSTL - PRG
2 stops32h 15mLufthansa
mié. 1/74:45 pmPRG - STL
2 stops38h 14mLufthansa
Deal found 12/4$1,130
This Ovago deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/259:08 amSTL - PRG
2 stops18h 52mMultiple Airlines
mié. 1/79:30 pmPRG - STL
2 stops28h 04mMultiple Airlines
Deal found 12/3$1,202
This Ovago deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/266:35 pmSTL - PRG
2 stops20h 50mMultiple Airlines
mié. 1/76:50 amPRG - STL
2 stops16h 13mMultiple Airlines
Deal found 12/2$1,219
This United Airlines deal was found by Cheapflights users on 12/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/2511:05 amSTL - PRG
2 stops19h 50mUnited Airlines
mié. 1/73:10 pmPRG - STL
2 stops33h 33mUnited Airlines
Deal found 12/4$1,259
This Mytrip deal was found by Cheapflights users on 12/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 12/306:15 pmMCI - PRG
3 stops35h 50mMultiple Airlines
vie. 1/911:55 amPRG - MCI
3 stops35h 14mMultiple Airlines
Deal found 12/3$1,287
This United Airlines deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/263:50 pmSTL - PRG
1 stop15h 15mUnited Airlines
mié. 1/76:50 amPRG - STL
2 stops21h 23mUnited Airlines
Deal found 12/2$1,311
This Ovago deal was found by Cheapflights users on 12/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/226:35 pmSTL - PRG
2 stops32h 00mLufthansa
lun. 12/296:55 pmPRG - STL
2 stops33h 48mLufthansa
Deal found 12/2$1,365

Find flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated diciembre 4, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$443
(oojo)

One-way from

$304
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$1,101
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Václav Havel Prague
Search Deals
One-way flight from Missouri to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($304 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 4, 2025.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mié. 2/4

1:56 pm-5:30 pm

2 stops20h 34m

Václav Havel Prague

mié. 2/11

6:50 am-9:06 pm

2 stops21h 16m

$444

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mié. 3/18

7:57 pm-8:40 pm

2 stops18h 43m

Václav Havel Prague

lun. 3/23

9:35 pm-10:20 pm

2 stops30h 45m

$446

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mié. 2/4

5:11 pm-5:30 pm

2 stops17h 19m

Václav Havel Prague

mié. 2/11

6:50 am-9:06 pm

2 stops21h 16m

$458

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

lun. 1/12

3:11 pm-1:05 pm

2 stops14h 54m

Václav Havel Prague

jue. 1/22

1:45 pm-10:58 pm

2 stops16h 13m

$483

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

lun. 1/12

3:11 pm-1:05 pm

2 stops14h 54m

Václav Havel Prague

mar. 1/20

1:45 pm-10:58 pm

2 stops16h 13m

$484

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

mié. 3/4

4:05 pm-1:55 pm

2 stops14h 50m

Václav Havel Prague

mar. 3/10

7:25 am-3:29 pm

2 stops38h 04m

$485

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

lun. 1/12

6:40 pm-4:05 pm

2 stops14h 25m

Václav Havel Prague

dom. 1/25

1:45 pm-10:58 pm

2 stops16h 13m

$494

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

dom. 1/11

5:49 pm-10:50 pm

2 stops22h 01m

Václav Havel Prague

mar. 1/20

9:20 pm-11:12 pm

2 stops32h 52m

$494

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

lun. 1/12

3:11 pm-1:05 pm

2 stops14h 54m

Václav Havel Prague

lun. 1/26

1:45 pm-10:58 pm

2 stops16h 13m

$494

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

mié. 4/22

6:08 pm-3:45 pm

2 stops14h 37m

Václav Havel Prague

sáb. 5/2

11:00 am-11:40 pm

2 stops19h 40m

$494

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/2

Showing 1-10 of 37 results
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Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $357). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PRG?

Find hourly flight availability from Missouri to Prague. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated diciembre 4, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Prague in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    British Airways, American Airlines, and United Airlines can get you from Missouri to Prague in just under 14h 54m. Your travel time can differ by up to 5h 40m. The distance from Missouri to Prague is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $357). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Prague

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Prague

Discover the top 7 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 4, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$383Average$818FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$556Average$997FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$742FlexibilityNo cancel feeOn-time70%
DeltaCheapest$608Average$1,204FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$711Average$959FlexibilityNo cancel feeOn-time71%
KLMCheapest$731Average$1,303FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$745Average$1,087FlexibilityNo cancel feeOn-time67%

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