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$261+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
Feb 5 — Feb 121
Thu 2/5
Thu 2/12
1 adult, Economy
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Cheap flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated January 6, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$445
(oojo)

One-way from

$261
(oojo)

Popular in

May

Cheapest in

February
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
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From Missouri to Václav Havel Prague
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One-way flight from Missouri to Václav Havel Prague
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Highest demand for flights based on searches. 21% potential increase in price ($248 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($41 potential savings vs. average RT price).
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Find flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 6, 2026.

This oojo deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/312:11 pmSTL - PRG
2 stops17h 44mBritish Airways
Tue 2/1010:55 amPRG - STL
2 stops19h 04mBritish Airways
Deal found 1/6$445
This oojo deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/411:02 amMCI - PRG
2 stops23h 28mBritish Airways
Tue 3/109:20 pmPRG - MCI
2 stops31h 08mBritish Airways
Deal found 1/5$446
This Finnair deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1811:22 amSTL - PRG
2 stops25h 28mFinnair
Wed 4/811:35 amPRG - STL
2 stops17h 39mFinnair
Deal found 1/5$462
This oojo deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/195:15 amMCI - PRG
2 stops25h 25mBritish Airways
Thu 2/269:30 pmPRG - MCI
2 stops26h 38mBritish Airways
Deal found 1/6$471
This KAYAK deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/1611:02 amMCI - PRG
2 stops23h 28mBritish Airways
Mon 2/239:35 pmPRG - MCI
2 stops32h 09mBritish Airways
Deal found 1/6$472
This American Airlines deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1912:36 pmMCI - PRG
2 stops18h 04mAmerican Airlines
Thu 2/2611:40 amPRG - MCI
2 stops19h 18mAmerican Airlines
Deal found 1/6$483
This Gotogate deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:05 pmSTL - PRG
2 stops14h 50mAir Canada
Tue 3/177:25 amPRG - STL
2 stops38h 04mAir Canada
Deal found 1/4$484
This Finnair deal was found by Cheapflights users on 1/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/125:12 amSTL - PRG
2 stops30h 38mMultiple Airlines
Mon 2/237:35 pmPRG - STL
2 stops30h 54mMultiple Airlines
Deal found 1/5$487
This oojo deal was found by Cheapflights users on 1/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/292:29 pmSTL - PRG
2 stops15h 46mBritish Airways
Sat 5/911:05 amPRG - STL
2 stops18h 09mBritish Airways
Deal found 1/6$495
This oojo deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/16:38 pmSTL - PRG
2 stops19h 07mBritish Airways
Sat 3/77:15 pmPRG - STL
2 stops31h 56mBritish Airways
Deal found 1/4$496
This Gotogate deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:05 pmSTL - PRG
2 stops14h 50mMultiple Airlines
Tue 3/176:55 pmPRG - STL
1 stop26h 00mMultiple Airlines
Deal found 1/4$500
This Mytrip deal was found by Cheapflights users on 1/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/14:05 pmSTL - PRG
2 stops14h 50mMultiple Airlines
Sat 3/73:10 pmPRG - STL
1 stop29h 45mMultiple Airlines
Deal found 1/4$503

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 3/1

6:38 pm-6:10 pm

2 stops16h 32m

Václav Havel Prague

Tue 3/10

10:55 am-11:48 pm

2 stops18h 53m

$496

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 2/19

11:02 am-6:05 pm

2 stops24h 03m

Václav Havel Prague

Thu 2/26

10:30 am-10:49 pm

2 stops19h 19m

$496

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Fri 2/20

2:12 pm-11:55 am

2 stops14h 43m

Václav Havel Prague

Tue 2/24

6:30 am-5:02 pm

2 stops17h 32m

$505

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 2/18

1:23 pm-11:40 am

2 stops15h 17m

Václav Havel Prague

Sat 2/28

9:50 am-8:39 pm

2 stops17h 49m

$505

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 2/19

2:12 pm-11:40 am

2 stops14h 28m

Václav Havel Prague

Sat 2/28

6:00 am-5:02 pm

2 stops18h 02m

$509

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 2/19

2:12 pm-5:05 pm

2 stops19h 53m

Václav Havel Prague

Mon 2/23

2:30 pm-3:29 pm

2 stops31h 59m

$509

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Fri 2/20

2:12 pm-11:55 am

2 stops14h 43m

Václav Havel Prague

Mon 2/23

8:55 am-11:40 pm

2 stops21h 45m

$509

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 3/4

5:21 pm-4:05 pm

2 stops15h 44m

Václav Havel Prague

Sun 3/8

7:25 am-7:41 pm

2 stops19h 16m

$510

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 3/11

5:00 am-6:50 pm

2 stops31h 50m

Václav Havel Prague

Wed 3/18

7:35 pm-12:11 am

2 stops34h 36m

$512

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 3/4

10:24 am-11:05 am

3 stops17h 41m

Václav Havel Prague

Tue 3/10

7:25 am-9:59 pm

3 stops20h 34m

$534

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/4

Showing 1-10 of 35 results
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Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    British Airways, Delta, and Lufthansa can get you from Missouri to Prague in just under 12h 20m. Your travel time can differ by up to 4h 12m. The distance from Missouri to Prague is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Prague

See prices for flight routes from nearby airports that may be better suited for you.
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Top 5 airlines flying from Missouri to Prague

Discover the top 5 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 6, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$383Average$797FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$548Average$959FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$556Average$947FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$742FlexibilityNo cancel feeOn-time70%
DeltaCheapest$608Average$1,217FlexibilityNo cancel feeOn-timeN/A

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