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Prague

$301+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This FlightHub deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/296:35 pm
STL
-
PRG
2 stops19h 45m
Lufthansa
Wed 4/86:10 am
PRG
-
STL
1 stop14h 15m
Lufthansa
Deal found 1/28$493
This oojo deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/102:00 pm
STL
-
PRG
2 stops24h 40m
British Airways
Tue 3/1710:55 am
PRG
-
STL
2 stops18h 49m
British Airways
Deal found 1/28$497
This oojo deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:28 am
MCI
-
PRG
2 stops24h 12m
British Airways
Thu 3/59:30 pm
PRG
-
MCI
2 stops32h 38m
British Airways
Deal found 1/27$497
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:35 pm
STL
-
PRG
2 stops19h 45m
United Airlines
Fri 5/86:00 am
PRG
-
STL
1 stop14h 25m
United Airlines
Deal found 1/26$500
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/49:55 am
STL
-
PRG
2 stops29h 30m
United Airlines
Wed 3/117:30 am
PRG
-
STL
1 stop13h 25m
United Airlines
Deal found 1/28$501
This FlightHub deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:45 pm
STL
-
PRG
2 stops16h 30m
Lufthansa
Fri 3/137:35 am
PRG
-
STL
1 stop13h 20m
Lufthansa
Deal found 1/29$507
This Delta deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:10 am
STL
-
PRG
2 stops22h 30m
Delta
Wed 3/116:00 am
PRG
-
STL
2 stops23h 58m
Delta
Deal found 1/28$510
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:15 am
MCI
-
PRG
2 stops34h 10m
United Airlines
Wed 3/187:30 am
PRG
-
MCI
2 stops32h 00m
United Airlines
Deal found 1/26$510
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/410:24 am
MCI
-
PRG
2 stops22h 41m
United Airlines
Sun 3/87:25 am
PRG
-
MCI
2 stops19h 16m
United Airlines
Deal found 1/28$511
This United Airlines deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/111:15 am
STL
-
PRG
2 stops23h 40m
United Airlines
Wed 4/82:35 pm
PRG
-
STL
2 stops15h 21m
United Airlines
Deal found 1/28$512
This Finnair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Finnair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/45:00 am
MCI
-
PRG
2 stops30h 50m
Multiple Airlines
Sun 3/87:35 pm
PRG
-
MCI
2 stops33h 14m
Multiple Airlines
Deal found 1/27$512
This KAYAK deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/182:50 pm
STL
-
PRG
2 stops25h 35m
Lufthansa
Wed 3/257:30 am
PRG
-
STL
2 stops16h 30m
Lufthansa
Deal found 1/28$531

Find flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$493
(FlightHub)

One-way from

$301
(Expedia)

Popular in

May

Cheapest in

April
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Václav Havel Prague
Search Deals
One-way flight from Missouri to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($188 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($43 potential savings vs. average RT price).
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 2/26

6:28 am-1:40 pm

2 stops24h 12m

Václav Havel Prague

Thu 3/5

9:30 pm-11:08 pm

2 stops32h 38m

$497

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 4/29

6:35 pm-9:20 pm

2 stops19h 45m

Václav Havel Prague

Fri 5/8

6:00 am-1:25 pm

1 stop14h 25m

$500

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 2/27

6:45 pm-6:15 pm

2 stops16h 30m

Václav Havel Prague

Fri 3/13

7:35 am-2:55 pm

1 stop13h 20m

$507

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 3/4

6:10 am-11:40 am

2 stops22h 30m

Václav Havel Prague

Wed 3/11

6:00 am-11:58 pm

2 stops23h 58m

$510

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 3/11

6:15 am-10:25 pm

2 stops34h 10m

Václav Havel Prague

Wed 3/18

7:30 am-9:30 am

2 stops32h 00m

$510

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 4/29

12:11 pm-6:45 pm

2 stops23h 34m

Václav Havel Prague

Fri 5/8

8:40 am-7:30 pm

2 stops17h 50m

$511

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 3/4

10:24 am-4:05 pm

2 stops22h 41m

Václav Havel Prague

Sun 3/8

7:25 am-7:41 pm

2 stops19h 16m

$511

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 3/4

5:00 am-6:50 pm

2 stops30h 50m

Václav Havel Prague

Sun 3/8

7:35 pm-10:49 pm

2 stops33h 14m

$512

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 4/1

11:15 am-5:55 pm

2 stops23h 40m

Václav Havel Prague

Wed 4/8

2:35 pm-10:56 pm

2 stops15h 21m

$512

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Wed 3/18

7:40 am-10:50 am

2 stops21h 10m

Václav Havel Prague

Wed 3/25

7:30 am-9:42 pm

2 stops20h 12m

$512

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 34 results
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Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Missouri to Prague?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    British Airways, United Airlines, and Lufthansa can get you from Missouri to Prague in just under 16h 30m. Your travel time can differ by up to 7h 42m. The distance from Missouri to Prague is about 4783 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $355). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Prague

See prices for flight routes from nearby airports that may be better suited for you.
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Norfolk to Prague flights

Top 5 airlines flying from Missouri to Prague

Discover the top 5 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$383Average$797FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$548Average$959FlexibilityNo cancel feeOn-time71%
LufthansaCheapest$556Average$855FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$742FlexibilityNo cancel feeOn-time70%
DeltaCheapest$608Average$1,217FlexibilityNo cancel feeOn-timeN/A

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