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$447+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/315:42 pmMCI - PRG
2 stops16h 23mDelta
Wed 1/146:00 amPRG - MCI
2 stops22h 05mDelta
Deal found 11/5$506
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:08 amMCI - PRG
2 stops31h 17mUnited Airlines
Sat 12/203:10 pmPRG - MCI
2 stops37h 40mUnited Airlines
Deal found 11/5$842
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/3111:24 amMCI - PRG
3 stops18h 41mAir Canada
Wed 1/147:30 amPRG - MCI
3 stops21h 29mAir Canada
Deal found 11/6$908
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/234:40 pmMCI - PRG
2 stops40h 25mUnited Airlines
Wed 12/316:15 amPRG - MCI
2 stops22h 35mUnited Airlines
Deal found 11/5$967
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:00 pmMCI - PRG
2 stops42h 05mUnited Airlines
Tue 12/306:50 amPRG - MCI
2 stops22h 00mUnited Airlines
Deal found 11/5$968
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/233:00 pmMCI - PRG
2 stops42h 05mUnited Airlines
Mon 12/2911:50 amPRG - MCI
2 stops38h 52mUnited Airlines
Deal found 11/5$984
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:50 amMCI - PRG
2 stops27h 20mScandinavian Airlines
Mon 11/1010:25 amPRG - MCI
2 stops17h 45mScandinavian Airlines
Deal found 11/4$997
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/92:49 pmMCI - PRG
2 stops19h 16mDelta
Wed 12/312:30 pmPRG - MCI
2 stops16h 26mDelta
Deal found 11/5$1,026
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/85:10 pmMCI - PRG
2 stops22h 15mUnited Airlines
Tue 12/306:15 amPRG - MCI
2 stops22h 35mUnited Airlines
Deal found 11/5$1,027
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/81:40 pmMCI - PRG
2 stops25h 45mUnited Airlines
Mon 12/291:45 pmPRG - MCI
2 stops37h 37mUnited Airlines
Deal found 11/5$1,036
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/111:40 pmMCI - PRG
2 stops25h 45mUnited Airlines
Tue 12/306:15 amPRG - MCI
2 stops22h 35mUnited Airlines
Deal found 11/5$1,039
This Air Canada deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/254:05 pmSTL - PRG
2 stops39h 00mMultiple Airlines
Wed 1/76:45 amPRG - STL
2 stops39h 44mMultiple Airlines
Deal found 11/6$1,057

Cheap flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated November 6, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(Cheapflightsfares)

One-way from

$447
(United)

Popular in

June

Cheapest in

March

Average price

$754
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Václav Havel Prague
Search Deals
One-way flight from Missouri to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($302 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/11

5:45 pm-10:25 pm

2 stops21h 40m

Václav Havel Prague

Tue 1/20

7:25 am-9:59 pm

2 stops21h 34m

$500

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/11

6:30 pm-1:05 pm

2 stops35h 35m

Václav Havel Prague

Tue 1/20

7:25 am-10:32 am

2 stops34h 07m

$506

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 12/31

5:42 pm-5:05 pm

2 stops16h 23m

Václav Havel Prague

Wed 1/14

11:35 am-9:05 pm

2 stops16h 30m

$506

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/4

5:00 pm-6:10 pm

2 stops18h 10m

Václav Havel Prague

Thu 1/15

6:45 am-6:03 pm

2 stops18h 18m

$604

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/4

5:30 am-1:35 pm

2 stops25h 05m

Václav Havel Prague

Wed 1/14

6:50 am-9:06 pm

2 stops21h 16m

$604

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 3/27

4:50 pm-2:05 pm

1 stop15h 15m

Václav Havel Prague

Tue 3/31

6:00 am-2:18 pm

2 stops15h 18m

$753

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 3/27

4:50 pm-9:50 am

1 stop11h 00m

Václav Havel Prague

Tue 3/31

6:50 pm-1:30 pm

1 stop25h 40m

$764

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 5/1

1:30 pm-12:45 pm

2 stops16h 15m

Václav Havel Prague

Sun 5/10

6:10 am-1:30 pm

1 stop14h 20m

$771

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Fri 5/1

3:30 pm-1:40 pm

1 stop15h 10m

Václav Havel Prague

Sun 5/10

6:10 am-1:30 pm

1 stop14h 20m

$779

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Sun 5/3

10:00 pm-7:55 am

2 stops26h 55m

Václav Havel Prague

Sat 5/9

7:30 pm-7:30 pm

2 stops31h 00m

$783

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/5

Showing 1-10 of 26 results
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Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $534). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PRG?

Find hourly flight availability from Missouri to Prague. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Prague in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Missouri to Prague?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    Lufthansa, United Airlines, and Delta can get you from Missouri to Prague in just under 16h 23m. Your travel time can differ by up to 19h 12m. The distance from Missouri to Prague is about 4907 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Prague one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as $476. Users have also found prices from $524 and $746 on Lufthansa and Turkish Airlines, respectively.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $534). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 7 airlines flying from Missouri to Prague

Discover the top 7 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$509Average$876FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$571Average$968FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$762FlexibilityNo cancel feeOn-time70%
DeltaCheapest$628Average$1,169FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$711Average$959FlexibilityNo cancel feeOn-time71%
KLMCheapest$731Average$1,303FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$745Average$1,087FlexibilityNo cancel feeOn-time67%

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