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$329+ Cheap flights from Missouri to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PRG
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Missouri to Prague

Cheapest flights from Missouri to Prague
Explore the most affordable flight options available from Missouri to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/313:19 pmMCI - PRG
2 stops17h 46mUnited Airlines
Wed 1/147:30 amPRG - MCI
2 stops21h 29mUnited Airlines
Deal found 11/13$506
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:05 pmSTL - PRG
2 stops16h 00mDelta
Tue 12/166:00 amPRG - STL
2 stops17h 35mDelta
Deal found 11/11$507
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:02 pmSTL - PRG
2 stops37h 53mUnited Airlines
Wed 1/77:30 amPRG - STL
1 stop13h 25mUnited Airlines
Deal found 11/13$596
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:28 pmSTL - PRG
2 stops17h 07mDelta
Mon 12/152:30 pmPRG - STL
2 stops33h 05mDelta
Deal found 11/11$612
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:05 pmSTL - PRG
2 stops16h 00mDelta
Wed 12/1711:35 amPRG - STL
2 stops27h 45mDelta
Deal found 11/11$692
This Expedia deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:43 pmSTL - PRG
2 stops20h 42mLufthansa
Fri 12/57:35 amPRG - STL
1 stop13h 20mLufthansa
Deal found 11/13$695
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:05 pmSTL - PRG
2 stops16h 00mDelta
Thu 12/189:50 amPRG - STL
2 stops19h 07mDelta
Deal found 11/11$697
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/286:43 pmSTL - PRG
2 stops20h 42mUnited Airlines
Fri 12/512:10 pmPRG - STL
2 stops34h 19mUnited Airlines
Deal found 11/13$701
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:24 pmSTL - PRG
2 stops15h 41mUnited Airlines
Tue 12/97:25 amPRG - STL
2 stops17h 05mUnited Airlines
Deal found 11/13$705
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:43 pmSTL - PRG
2 stops14h 22mUnited Airlines
Sun 12/76:15 amPRG - STL
2 stops23h 30mUnited Airlines
Deal found 11/13$707
This United Airlines deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:43 pmSTL - PRG
2 stops14h 22mUnited Airlines
Sat 12/136:50 amPRG - STL
2 stops22h 55mUnited Airlines
Deal found 11/13$708
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/126:00 amMCI - PRG
2 stops24h 55mUnited Airlines
Tue 12/167:25 amPRG - MCI
2 stops34h 14mUnited Airlines
Deal found 11/12$708

Cheap flight deals from Missouri to Prague

Keep the following information in mind while searching for Missouri to Prague flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(Cheapflightsfares)

One-way from

$329
(Kiwi.com)

Popular in

June

Cheapest in

March

Average price

$754
Provider with most accurate pricing for Lambert-St Louis-Václav Havel Prague flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Václav Havel Prague flights.
Search Deals
From Missouri to Václav Havel Prague
Search Deals
One-way flight from Missouri to Václav Havel Prague
Search Deals
Highest demand for flights based on searches. 24% potential increase in price ($304 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Missouri to Prague that are best for you.

Fly from

Missouri

Fly to

Prague

Route

Depart

Return

Price

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/11

6:30 pm-10:25 pm

2 stops20h 55m

Václav Havel Prague

Tue 1/20

7:25 am-9:59 pm

2 stops21h 34m

$500

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Wed 12/31

11:24 am-1:05 pm

2 stops18h 41m

Václav Havel Prague

Wed 1/14

7:30 am-9:59 pm

2 stops21h 29m

$506

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 1/8

9:05 am-10:25 pm

2 stops30h 20m

Václav Havel Prague

Fri 1/16

7:35 am-7:56 pm

2 stops19h 21m

$506

St. LouisPrague

STL - PRG

STLPRG

Lambert-St Louis

Thu 12/25

5:02 pm-1:55 pm

2 stops37h 53m

Václav Havel Prague

Wed 1/7

7:30 am-1:55 pm

1 stop13h 25m

$596

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Fri 2/27

12:37 pm-1:05 pm

2 stops17h 28m

Václav Havel Prague

Tue 3/10

7:25 am-8:04 pm

2 stops18h 39m

$606

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Fri 2/27

12:37 pm-4:05 pm

2 stops20h 28m

Václav Havel Prague

Wed 3/11

7:30 am-9:35 pm

2 stops20h 05m

$606

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/11

11:29 am-1:05 pm

3 stops18h 36m

Václav Havel Prague

Tue 1/20

7:25 am-7:57 pm

3 stops19h 32m

$613

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/4

1:48 pm-1:35 pm

2 stops16h 47m

Václav Havel Prague

Thu 1/15

9:30 pm-10:39 pm

2 stops32h 09m

$616

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Sun 1/4

4:59 pm-6:10 pm

2 stops18h 11m

Václav Havel Prague

Wed 1/14

9:30 pm-9:06 pm

2 stops30h 36m

$616

Kansas CityPrague

MCI - PRG

MCIPRG

Kansas City

Thu 1/1

7:40 am-10:25 pm

2 stops31h 45m

Václav Havel Prague

Wed 1/7

3:10 pm-7:56 pm

2 stops35h 46m

$617

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/13

Showing 1-10 of 27 results
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Best time to book a flight from Missouri to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Prague

What is the cheapest month to book a flight from Missouri to Prague?

Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $343). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PRG?

Find hourly flight availability from Missouri to Prague. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Missouri to Prague in the evening. If you’re flexible enough to do this you can expect to save up to 22% on your trip compared to booking a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Prague from Missouri?

    Václav Havel Prague (PRG), located 6.9 mi from the city center, is the airport you fly into when you book flights from Missouri to Prague.

  • How long is the flight from Missouri to Prague?

    Lufthansa and United Airlines can get you from Missouri to Prague in just under 18h 41m. Your travel time can differ by up to 2h 14m. The distance from Missouri to Prague is about 4907 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Missouri to Prague that include hotel bookings?

    Yes. In addition to deals on Missouri to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Prague.

  • Can I find deals for business class flights from Missouri to Prague?

    Yes. Cheapflights offers flight deals from Missouri to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Prague?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Prague (average of $343). Flying from Missouri to Prague in June is currently the most expensive (average of $1,071). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Prague

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Prague

Discover the top 7 airlines that operate flights from Missouri to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$509Average$876FlexibilityNo cancel feeOn-time69%
LufthansaCheapest$571Average$968FlexibilityNo cancel feeOn-time76%
British AirwaysCheapest$582Average$762FlexibilityNo cancel feeOn-time70%
DeltaCheapest$628Average$1,169FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$711Average$959FlexibilityNo cancel feeOn-time71%
KLMCheapest$731Average$1,303FlexibilityNo cancel feeOn-time75%
Air CanadaCheapest$745Average$1,087FlexibilityNo cancel feeOn-time67%

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