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$435+ Cheap flights from Des Moines (DSM) to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/26. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PRG
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheap flight deals from Des Moines to Prague

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Prague (PRG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$622
(United Airlines)

One-way from

$435
(Kiwi.com)

Popular in

March

Cheapest in

January

Average price

$1,445
From Des Moines to Václav Havel Prague
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One-way flight from Des Moines to Václav Havel Prague
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Highest demand for flights based on searches. 3% potential increase in price ($32 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($49 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Des Moines to Prague

Cheapest flights from Des Moines to Prague
Explore the most affordable flight options available from Des Moines to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/253:15 pmDSM - PRG
2 stops15h 40mUnited Airlines
Fri 12/510:10 amPRG - DSM
2 stops18h 26mUnited Airlines
Deal found 6/10$622
This British Airways deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure British Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/264:26 pmDSM - PRG
2 stops23h 24mBritish Airways
Fri 12/56:00 amPRG - DSM
2 stops21h 06mBritish Airways
Deal found 6/10$624
This Lufthansa deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Lufthansa is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/261:05 pmDSM - PRG
2 stops26h 20mLufthansa
Tue 12/27:20 amPRG - DSM
2 stops21h 16mLufthansa
Deal found 6/10$625
This AirNGo deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure AirNGo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/46:50 pmDSM - PRG
2 stops34h 20mAir Canada
Wed 8/131:40 pmPRG - DSM
2 stops51h 49mAir Canada
Deal found 6/11$641
This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/76:30 pmDSM - PRG
2 stops18h 05mDelta
Wed 9/176:30 amPRG - DSM
2 stops20h 23mDelta
Deal found 6/10$699
This Expedia deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/45:52 pmDSM - PRG
2 stops19h 08mAir France
Wed 8/138:25 pmPRG - DSM
2 stops33h 18mAir France
Deal found 6/11$709
This KLM deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KLM is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:30 pmDSM - PRG
2 stops16h 10mKLM
Sun 9/216:00 amPRG - DSM
2 stops17h 45mKLM
Deal found 6/9$854
This FlightHub deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2011:04 amDSM - PRG
2 stops26h 41mScandinavian Airlines
Thu 9/258:55 pmPRG - DSM
2 stops32h 28mScandinavian Airlines
Deal found 6/11$859
This lastminute.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure lastminute.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/256:40 pmDSM - PRG
2 stops16h 05mMultiple Airlines
Fri 8/16:00 amPRG - DSM
2 stops17h 40mMultiple Airlines
Deal found 6/10$1,036

Cheapflights Fare Finder

Customize your flight search to find flights from Des Moines to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Des Moines to Prague that are best for you.

Fly from

Des Moines

Fly to

Prague

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 11/25

3:15 pm-1:55 pm

2 stops15h 40m

Václav Havel Prague

Tue 12/2

7:20 am-8:32 pm

2 stops20h 12m

$622

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 11/26

4:26 pm-10:50 pm

2 stops23h 24m

Václav Havel Prague

Fri 12/5

6:00 am-8:06 pm

2 stops21h 06m

$624

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 11/26

6:50 pm-10:25 pm

2 stops20h 35m

Václav Havel Prague

Wed 12/3

7:20 am-9:36 pm

2 stops21h 16m

$625

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Mon 8/4

6:50 pm-12:10 pm

2 stops34h 20m

Václav Havel Prague

Wed 8/13

1:40 pm-10:29 am

2 stops51h 49m

$641

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sun 9/7

6:30 pm-7:35 pm

2 stops18h 05m

Václav Havel Prague

Wed 9/17

6:30 am-7:53 pm

2 stops20h 23m

$699

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Mon 8/4

5:52 pm-8:00 pm

2 stops19h 08m

Václav Havel Prague

Wed 8/13

8:25 pm-10:43 pm

2 stops33h 18m

$709

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Thu 9/11

6:30 pm-5:40 pm

2 stops16h 10m

Václav Havel Prague

Sun 9/21

6:00 am-4:45 pm

2 stops17h 45m

$854

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sat 9/20

11:04 am-8:45 pm

2 stops26h 41m

Václav Havel Prague

Thu 9/25

8:55 pm-10:23 pm

2 stops32h 28m

$859

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 7/25

6:40 pm-5:45 pm

2 stops16h 05m

Václav Havel Prague

Fri 8/1

6:00 am-4:40 pm

2 stops17h 40m

$1,036

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sat 7/26

1:13 pm-1:40 pm

3 stops41h 27m

$435

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Showing 1-10 of 12 results
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Best time to book a flight from Des Moines to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Prague

What is the cheapest month to book a flight from Des Moines to Prague?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Prague (average of $651). Flying from Des Moines to Prague in June is currently the most expensive (average of $1,132). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Prague by month

Plan your trip to Prague by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Prague ranges from 0.4 - 2.4 inches per month. June is typically the wettest month, when rainfall can reach 2.4 in. February is typically the driest time to visit Prague when rainfall is around 0.4 in.

Temperature in Prague by month

Plan your trip to Prague by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Prague, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 62.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 30.2 F).

Reviews of airlines servicing Prague

Get insights into the airlines that provide service to Prague. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Prague. Reviews last updated June 12, 2025.
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
KLM
7.8
Good
1,358 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air France
7.5
Good
1,463 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Scandinavian Airlines
7.3
Good
1,387 reviews
Delta
8.0
Very good
7,946 reviews

Food

7.3

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Prague round-trip?

    Our cheapest airline available from Des Moines to Prague is United Airlines. Our recent data shows that you can find tickets from as low as $622 on this airline. Additional options worth looking into are British Airways and Lufthansa, starting at $624 and $625 round-trip. United Airlines is priced at 35% lower than the current average price of a flight leaving 3 months from now.

  • Can I find deals for flights from Des Moines to Prague that include hotel bookings?

    Yes. In addition to deals on Des Moines to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Prague.

  • Can I find deals for business class flights from Des Moines to Prague?

    Yes. Cheapflights offers flight deals from Des Moines to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Prague?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Prague (average of $651). Flying from Des Moines to Prague in June is currently the most expensive (average of $1,132). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Des Moines to Prague

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Des Moines to Prague

Discover the top airline that operate flights from Des Moines to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$588Average$707FlexibilityNo cancel feeOn-time69%

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