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$517+ Cheap flights from Des Moines (DSM) to Prague (PRG)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PRG
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from Des Moines to Prague

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Prague (PRG). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 30, 2025.

Round-trip from

$658
(United Airlines)

One-way from

$517
(United Airlines)

Popular in

June

Cheapest in

January

Average price

$998
From Des Moines to Václav Havel Prague
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One-way flight from Des Moines to Václav Havel Prague
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Highest demand for flights based on searches. 18% potential increase in price ($212 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($58 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Des Moines to Prague

Cheapest flights from Des Moines to Prague
Explore the most affordable flight options available from Des Moines to Prague. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This United Airlines deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:25 pmDSM - PRG
2 stops19h 55mUnited Airlines
Wed 9/171:40 pmPRG - DSM
2 stops31h 30mUnited Airlines
Deal found 7/29$658
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/165:54 pmDSM - PRG
2 stops18h 41mDelta
Sun 9/2811:00 amPRG - DSM
2 stops30h 40mDelta
Deal found 7/30$796
This Air Canada deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1311:35 amDSM - PRG
3 stops16h 20mAir Canada
Sat 9/209:35 amPRG - DSM
3 stops19h 10mAir Canada
Deal found 7/30$978
This Mytrip deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/128:25 amDSM - PRG
3 stops29h 30mMultiple Airlines
Fri 9/192:00 pmPRG - DSM
3 stops27h 14mMultiple Airlines
Deal found 7/30$1,305

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Prague that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from Des Moines to Prague that are best for you.

Fly from

Des Moines

Fly to

Prague

Route

Depart

Return

Price

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Wed 9/10

6:25 pm-9:20 pm

2 stops19h 55m

Václav Havel Prague

Wed 9/17

1:40 pm-2:10 pm

2 stops31h 30m

$658

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Tue 9/16

5:54 pm-7:35 pm

2 stops18h 41m

Václav Havel Prague

Sun 9/28

11:00 am-10:40 am

2 stops30h 40m

$796

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sat 9/13

11:35 am-10:55 am

3 stops16h 20m

Václav Havel Prague

Sat 9/20

9:35 am-9:45 pm

3 stops19h 10m

$978

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 9/12

8:25 am-8:55 pm

3 stops29h 30m

Václav Havel Prague

Fri 9/19

2:00 pm-10:14 am

3 stops27h 14m

$1,305

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Fri 9/12

5:15 pm-12:10 pm

2 stops59h 55m

$517

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sun 12/7

12:43 pm-1:35 pm

2 stops17h 52m

$1,004

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sun 12/7

1:39 pm-3:00 pm

2 stops18h 21m

$1,144

Des MoinesPrague

DSM - PRG

DSMPRG

Des Moines

Sun 12/7

8:00 am-9:35 am

3 stops18h 35m

$1,224

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Best time to book a flight from Des Moines to Prague

Have a flexible travel schedule? Discover the best time to fly to Prague from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Prague

What is the cheapest month to book a flight from Des Moines to Prague?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Prague (average of $651). Flying from Des Moines to Prague in June is currently the most expensive (average of $1,118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Prague

Get insights into the airlines that provide service to Prague. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Prague. Reviews last updated July 30, 2025.
See what other customers who have flown with Delta, United Airlines, and Air Canada from Des Moines to Prague have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Air Canada
7.1
Good
9,837 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
British Airways
6.6
Okay
7,217 reviews
Delta
8.0
Very good
7,980 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Prague. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Des Moines to Prague round-trip?

    Our cheapest airline available from Des Moines to Prague is United Airlines. Our recent data shows that you can find tickets from as low as $658 on this airline. Additional options worth looking into are Delta and Air Canada, starting at $796 and $978 round-trip. United Airlines is priced at 31% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Des Moines to Prague one-way?

    To fly one-way, consider booking your trip with United Airlines, which is currently one of the cheapest options available, starting at $517. British Airways flights start at $1,004 while deals on Air Canada start at $1,224 one-way.

  • Can I find deals for flights from Des Moines to Prague that include hotel bookings?

    Yes. In addition to deals on Des Moines to Prague flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Prague?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Prague.

  • Can I find deals for business class flights from Des Moines to Prague?

    Yes. Cheapflights offers flight deals from Des Moines to Prague by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Prague?

    Currently, November is the cheapest month in which you can book a flight from Des Moines to Prague (average of $651). Flying from Des Moines to Prague in June is currently the most expensive (average of $1,118). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top airline flying from Des Moines to Prague

Discover the top airline that operate flights from Des Moines to Prague. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$588Average$804FlexibilityNo cancel feeOn-time69%

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