What’s the fastest layover option from Des Moines to Portland?

Flights via Denver (DEN) have the shortest average one-way travel time for 1-stop routes: 7h 17m.

Which airport typically offers the quickest layover for flights from Des Moines to Portland?

Flights via Dallas (DFW) offer the fastest connection on this route, with an average layover time of 1h 21m.

What’s the top layover airport for flights from Des Moines to Portland?

Dallas (DFW) – chosen by Cheapflights users on 50% of 1-stop itineraries from Des Moines to Portland on Cheapflights.

What’s the cheapest layover airport for flights from Des Moines to Portland?

Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of $128.

How popular is this Des Moines to Portland flight route?

The Des Moines to Portland flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

How long is the flight from Des Moines to Portland?

Departing from Des Moines to Portland will take you 3h 48m. The distance between Des Moines and Portland is about 1466 mi. This flight may include one or multiple stops.

What are the cheapest airlines flying from Des Moines to Portland round-trip?

Flying on Frontier is currently your cheapest option to Portland, with prices starting at $128. Additional round-trip tickets that might be worth considering are offered by Allegiant Air and Delta, with the lowest prices starting at $128 and $203, respectively. Frontier is currently priced 63% below the average price you’ll pay for this route.

What are the cheapest airlines to fly from Des Moines to Portland one-way?

The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $106. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Des Moines to Portland for a low price.

What is the cheapest day to fly from Des Moines to Portland?

Travelers seeking maximum savings on their Des Moines to Portland flight should consider departing on Friday mornings when fares are most often at their lowest. Saturday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Portland ranges from 0.7 - 5.6 inches per month. November is typically the wettest month, when rainfall can reach 5.6 in. July is typically the driest time to visit Portland when rainfall is around 0.7 in.

If weather is an important factor for your trip to Portland, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 69.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 41.0 F).

What are the cheapest flights from Des Moines to Portland?

While on average a flight from Des Moines to Portland is generally $160, our data shows the cheapest flight currently is $71. When looking at the most popular route, (Des Moines - Portland), you can expect to pay $148 for that flight.

What are the most popular airlines that fly from Des Moines to Portland?

American Airlines, Delta and Frontier are the most popular airlines when flying from Des Moines to Portland.

Most accurate provider : When it comes to deals on Des Moines-Portland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Portland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Portland flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Portland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Portland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Can I find deals for flights from Des Moines to Portland that include hotel bookings?

Yes. In addition to deals on Des Moines to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Portland?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Portland.

Can I find deals for business class flights from Des Moines to Portland?

Yes. Cheapflights offers flight deals from Des Moines to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$93+ Cheap Flights from Des Moines to Portland

Home Search by date Vacation packages Hotels Flight deals Car rental Travel tips & news

Find cheap flights from Des Moines to Portland with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Des Moines to Portland are usually found in August or October, booked 73 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Des Moines to Portland

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$148 (Cheapflightsfares)
One-way from	$93 (Kiwi.com)
Popular in	December
Cheapest in	August
Average price	$298
Good round-trip deal	$141 or less
Good one-way deal	$116 or less

Provider with most accurate pricing for Des Moines-Portland flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Portland flights.

Search Deals

From Des Moines to Portland

Search Deals

One-way flight from Des Moines to Portland

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($78 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Price to beat on a round-trip flight from Des Moines to Portland.

Search Deals

Price to beat on a one-way flight from Des Moines to Portland.

Search Deals

Find flight deals from Des Moines to Portland

Cheapest flights from Des Moines to Portland
Explore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 25, 2025.

dom. 10/127:00 amDSM - PDX

Nonstop3h 48mAllegiant Air

jue. 10/169:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/24

$148

jue. 10/27:00 amDSM - PDX

Nonstop3h 48mAllegiant Air

dom. 10/59:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/23

$186

dom. 10/197:00 amDSM - PDX

Nonstop3h 48mAllegiant Air

jue. 10/239:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/23

$195

dom. 10/197:00 amDSM - PDX

Nonstop3h 48mMultiple Airlines

jue. 10/2312:43 pmPDX - DSM

1 stop23h 09mMultiple Airlines

Deal found 9/23

$244

sáb. 11/83:30 pmDSM - PDX

1 stop6h 56mDelta

sáb. 11/1511:15 pmPDX - DSM

1 stop8h 26mDelta

Deal found 9/23

$261

sáb. 10/189:00 amDSM - PDX

1 stop25h 23mMultiple Airlines

mar. 10/2112:43 pmPDX - DSM

1 stop23h 09mMultiple Airlines

Deal found 9/24

$266

dom. 11/25:34 pmDSM - PDX

2 stops20h 22mMultiple Airlines

sáb. 11/812:52 pmPDX - DSM

1 stop22h 55mMultiple Airlines

Deal found 9/25

$270

jue. 9/257:00 amDSM - PDX

Nonstop3h 38mAllegiant Air

jue. 10/29:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/23

$272

vie. 10/32:25 pmDSM - PDX

1 stop11h 47mFrontier

dom. 10/56:05 amPDX - DSM

1 stop5h 35mFrontier

Deal found 9/23

$280

dom. 11/22:32 pmDSM - PDX

1 stop23h 24mFrontier

sáb. 11/812:52 pmPDX - DSM

1 stop22h 55mFrontier

Deal found 9/25

$283

jue. 10/22:25 pmDSM - PDX

2 stops21h 59mMultiple Airlines

dom. 10/59:38 amPDX - DSM

Nonstop3h 15mMultiple Airlines

Deal found 9/23

$293

vie. 10/32:25 pmDSM - PDX

1 stop11h 47mMultiple Airlines

dom. 10/59:38 amPDX - DSM

Nonstop3h 15mMultiple Airlines

Deal found 9/25

$294

Best flights from Des Moines to Portland
Discover carefully curated flight deals from Des Moines to Portland that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated septiembre 25, 2025.

dom. 10/197:00 amDSM - PDX

Nonstop3h 48mAllegiant Air

jue. 10/239:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/23

$195

mié. 12/33:38 pmDSM - PDX

1 stop7h 46mAmerican Airlines

mié. 12/105:30 amPDX - DSM

1 stop7h 21mAmerican Airlines

Deal found 9/25

$261

sáb. 11/811:06 amDSM - PDX

1 stop8h 21mDelta

vie. 11/1412:35 amPDX - DSM

1 stop7h 45mDelta

Deal found 9/23

$261

dom. 11/92:32 pmDSM - PDX

1 stop23h 24mMultiple Airlines

dom. 11/167:57 pmPDX - DSM

1 stop24h 43mMultiple Airlines

Deal found 9/24

$344

jue. 12/43:17 pmDSM - PDX

1 stop8h 58mUnited Airlines

mar. 12/91:00 pmPDX - DSM

2 stops8h 44mUnited Airlines

Deal found 9/25

$352

sáb. 11/17:03 amDSM - PDX

1 stop7h 47mDelta

sáb. 11/810:10 pmPDX - DSM

1 stop10h 32mDelta

Deal found 9/25

$300

jue. 12/42:54 pmDSM - PDX

1 stop7h 59mDelta

mar. 12/911:15 pmPDX - DSM

1 stop8h 25mDelta

Deal found 9/25

$304

lun. 12/84:59 pmDSM - PDX

1 stop5h 54mDelta

lun. 12/156:00 amPDX - DSM

1 stop6h 14mDelta

Deal found 9/25

$347

Last-minute flights from Des Moines to Portland
Discover last-minute flight deals from Des Moines to Portland. Data last updated septiembre 25, 2025 and is based on user searches.

jue. 9/257:00 amDSM - PDX

Nonstop3h 38mAllegiant Air

jue. 10/29:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/23

$272

jue. 9/252:25 pmDSM - PDX

1 stop11h 47mFrontier

jue. 10/26:05 amPDX - DSM

1 stop5h 35mFrontier

Deal found 9/23

$321

jue. 10/27:00 amDSM - PDX

Nonstop3h 48mAllegiant Air

dom. 10/59:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/23

$186

jue. 10/22:25 pmDSM - PDX

2 stops21h 59mMultiple Airlines

dom. 10/59:38 amPDX - DSM

Nonstop3h 15mMultiple Airlines

Deal found 9/23

$293

vie. 10/32:25 pmDSM - PDX

1 stop11h 47mFrontier

dom. 10/56:05 amPDX - DSM

1 stop5h 35mFrontier

Deal found 9/23

$280

vie. 10/32:25 pmDSM - PDX

1 stop11h 47mMultiple Airlines

dom. 10/59:38 amPDX - DSM

Nonstop3h 15mMultiple Airlines

Deal found 9/25

$294

vie. 10/103:40 pmDSM - PDX

2 stops23h 26mMultiple Airlines

mar. 10/1412:43 pmPDX - DSM

1 stop23h 09mMultiple Airlines

Deal found 9/25

$309

dom. 10/127:00 amDSM - PDX

Nonstop3h 48mAllegiant Air

jue. 10/169:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/24

$148

sáb. 10/189:00 amDSM - PDX

1 stop25h 23mMultiple Airlines

mar. 10/2112:43 pmPDX - DSM

1 stop23h 09mMultiple Airlines

Deal found 9/24

$266

dom. 10/197:00 amDSM - PDX

Nonstop3h 48mAllegiant Air

jue. 10/239:38 amPDX - DSM

Nonstop3h 15mAllegiant Air

Deal found 9/23

$195

dom. 10/197:00 amDSM - PDX

Nonstop3h 48mMultiple Airlines

jue. 10/2312:43 pmPDX - DSM

1 stop23h 09mMultiple Airlines

Deal found 9/23

$244

One-way flights from Des Moines to Portland
Search for one-way flight options from Des Moines to Portland. Find affordable one-way fares based on user searches. Data last updated septiembre 25, 2025.

vie. 10/312:32 pmDSM - PDX

1 stop23h 24mFrontier

Deal found 9/23

$93

lun. 11/32:32 pmDSM - PDX

1 stop23h 24mFrontier

Deal found 9/23

$98

jue. 10/302:32 pmDSM - PDX

1 stop23h 24mFrontier

Deal found 9/23

$106

mié. 10/292:40 pmDSM - PDX

1 stop7h 46mDelta

Deal found 9/23

$131

dom. 11/22:32 pmDSM - PDX

1 stop23h 24mFrontier

Deal found 9/23

$188

dom. 11/25:34 pmDSM - PDX

2 stops20h 22mMultiple Airlines

Deal found 9/23

$190

mar. 11/45:14 pmDSM - PDX

2 stops19h 39mUnited Airlines

Deal found 9/23

$215

mié. 10/295:45 amDSM - PDX

2 stops11h 01mUnited Airlines

Deal found 9/23

$219

sáb. 11/112:55 pmDSM - PDX

2 stops10h 40mSouthwest

Deal found 9/23

$223

lun. 11/311:06 amDSM - PDX

2 stops11h 45mDelta

Deal found 9/23

$312

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Portland that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

dom. 10/19

7:00 am-8:48 am

Nonstop3h 48m

Portland

jue. 10/23

9:38 am-2:53 pm

Nonstop3h 15m

$195

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

mié. 12/3

3:38 pm-9:24 pm

1 stop7h 46m

Portland

mié. 12/10

5:30 am-2:51 pm

1 stop7h 21m

$261

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

sáb. 11/8

11:06 am-5:27 pm

1 stop8h 21m

Portland

vie. 11/14

12:35 am-10:20 am

1 stop7h 45m

$261

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

sáb. 11/1

7:03 am-12:50 pm

1 stop7h 47m

Portland

sáb. 11/8

10:10 pm-10:42 am

1 stop10h 32m

$300

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

jue. 12/4

2:54 pm-8:53 pm

1 stop7h 59m

Portland

mar. 12/9

11:15 pm-9:40 am

1 stop8h 25m

$304

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

dom. 11/9

2:32 pm-11:56 am

1 stop23h 24m

Portland

dom. 11/16

7:57 pm-10:40 pm

1 stop24h 43m

$344

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

lun. 12/8

4:59 pm-8:53 pm

1 stop5h 54m

Portland

lun. 12/15

6:00 am-2:14 pm

1 stop6h 14m

$347

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

jue. 12/4

3:17 pm-10:15 pm

1 stop8h 58m

Portland

mar. 12/9

1:00 pm-11:44 pm

2 stops8h 44m

$352

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

jue. 10/30

2:32 pm-11:56 am

1 stop23h 24m

$106

Des MoinesPortland

DSM - PDX

DSMPDX

Des Moines

sáb. 11/1

6:07 pm-11:06 pm

1 stop6h 59m

$131

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/23

Showing 1-10 of 19 results

Compare providers for flights from Des Moines to Portland

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Portland in September.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy2 stars	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars
Mytrip	Price Accuracy3 stars	Trust Score*3 stars
Cheapflightsfares	Price Accuracy2 stars	Trust Score*1 star
Priceline	Price Accuracy1 star	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Portland flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Des Moines-Portland flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Des Moines-Portland flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Portland flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Portland flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Portland

Prices

How far ahead should I book a flight from Des Moines to Portland?

The best time to book flights from Des Moines to Portland is 73 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Des Moines to Portland?

Currently, November is the cheapest month in which you can book a flight from Des Moines to Portland (average of $277). Flying from Des Moines to Portland in March is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DSM to PDX?

It’s typically best to fly out from Des Moines to Portland in the morning. Doing so could potentially save you 43% on the flight price compared to flying in the evening, which is usually more expensive.

Reviews of airlines servicing Portland

Read through reviews of airlines operating flights from Des Moines to Portland, such as Southwest, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,246 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

United Airlines

7.4

Good

8,926 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Allegiant Air

7.2

Good

699 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Frontier

5.8

Fair

3,162 reviews

Southwest

8.0

Very good

4,246 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

How popular is this Des Moines to Portland flight route?
The Des Moines to Portland flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
How long is the flight from Des Moines to Portland?
Departing from Des Moines to Portland will take you 3h 48m. The distance between Des Moines and Portland is about 1466 mi. This flight may include one or multiple stops.
What are the cheapest airlines flying from Des Moines to Portland round-trip?
Flying on Frontier is currently your cheapest option to Portland, with prices starting at $128. Additional round-trip tickets that might be worth considering are offered by Allegiant Air and Delta, with the lowest prices starting at $128 and $203, respectively. Frontier is currently priced 63% below the average price you’ll pay for this route.
What are the cheapest airlines to fly from Des Moines to Portland one-way?
The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $106. However, be on the lookout for offers from American Airlines and Delta, as they are both options that can get you from Des Moines to Portland for a low price.
What are the cheapest flights from Des Moines to Portland?
While on average a flight from Des Moines to Portland is generally $160, our data shows the cheapest flight currently is $71. When looking at the most popular route, (Des Moines - Portland), you can expect to pay $148 for that flight.
Can I find deals for flights from Des Moines to Portland that include hotel bookings?
Yes. In addition to deals on Des Moines to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Portland?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Portland.
Can I find deals for business class flights from Des Moines to Portland?
Yes. Cheapflights offers flight deals from Des Moines to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Portland?
Currently, November is the cheapest month in which you can book a flight from Des Moines to Portland (average of $277). Flying from Des Moines to Portland in March is currently the most expensive (average of $368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Vancouver

Seaside

Beaverton

Clackamas

McMinnville

Lake Oswego

Hillsboro

Cannon Beach

Long Beach

Longview

Lincoln City

Tigard

Depoe Bay

Stevenson

Wilsonville

Pacific City

Tillamook

Troutdale

Gresham

Silverton

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Des Moines to Portland

Complete your trip

Portland car rentals

Portland Airport car rentals

Pearl District car rentals

Southeast Portland car rentals

Northeast Portand car rentals

Southwest Portland car rentals

North Portland car rentals

University Park car rentals

Other flights to Portland

Top 6 airlines flying from Des Moines to Portland

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$128	Average$251	FlexibilityNo cancel fee	On-time62%
Allegiant Air	Cheapest$128	Average$213	FlexibilityNo cancel fee	On-time88%
Delta	Cheapest$203	Average$408	FlexibilityNo cancel fee	On-timeN/A
American Airlines	Cheapest$298	Average$406	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$317	Average$457	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$336	Average$480	FlexibilityNo cancel fee	On-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

$93+ Cheap flights from Des Moines to Portland (DSM - PDX)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/31. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Portland with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Des Moines to Portland are usually found in August or October, booked 73 days in advance, depart on a Friday or Saturday and return on a Tuesday

Cheap flight deals from Des Moines to Portland

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Des Moines to Portland

Cheapest flights from Des Moines to PortlandExplore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 25, 2025.

Explore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 25, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Portland that are best for you.

Compare providers for flights from Des Moines to Portland

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Portland in September.

Best time to book a flight from Des Moines to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Portland

How far ahead should I book a flight from Des Moines to Portland?

What is the cheapest month to book a flight from Des Moines to Portland?

What is the cheapest time of day to fly from DSM to PDX?

What’s the top layover airport for flights from Des Moines to Portland?

What’s the fastest layover option from Des Moines to Portland?

What’s the fastest layover option from Des Moines to Portland?

Which airport typically offers the quickest layover for flights from Des Moines to Portland?

Reviews of airlines servicing Portland

Read through reviews of airlines operating flights from Des Moines to Portland, such as Southwest, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Des Moines to Portland flight route?

How long is the flight from Des Moines to Portland?

What are the cheapest airlines flying from Des Moines to Portland round-trip?

What are the cheapest airlines to fly from Des Moines to Portland one-way?

What are the cheapest flights from Des Moines to Portland?

Can I find deals for flights from Des Moines to Portland that include hotel bookings?

How can I find direct flights from Des Moines to Portland?

Can I find deals for business class flights from Des Moines to Portland?

What is the cheapest month to book a flight from Des Moines to Portland?

Traveling to a place near Portland?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Des Moines to Portland

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Des Moines to Portland

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Des Moines to Portland
Explore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 25, 2025.