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$115+ Cheap flights from Des Moines to Portland, ME (DSM - PWM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/30. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — PWM
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Des Moines to Portland are usually found in February or March, booked 45 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from Des Moines to Portland

Discover tips and strategies to find the most affordable flight options for your journey from Des Moines (DSM) to Portland (PWM). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$229
(American Airlines)

One-way from

$115
(United Airlines)

Popular in

December

Cheapest in

February

Average price

$385
From Des Moines to Portland
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One-way flight from Des Moines to Portland
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Highest demand for flights based on searches. 13% potential increase in price ($66 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Des Moines to Portland

Cheapest flights from Des Moines to Portland
Explore the most affordable flight options available from Des Moines to Portland. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/53:18 pmDSM - PWM
1 stop5h 17mAmerican Airlines
Wed 11/125:43 amPWM - DSM
1 stop7h 41mAmerican Airlines
Deal found 9/10$229
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/188:00 amDSM - PWM
2 stops10h 41mUnited Airlines
Wed 10/226:14 amPWM - DSM
1 stop5h 18mUnited Airlines
Deal found 9/10$234
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/52:13 pmDSM - PWM
1 stop7h 06mDelta
Wed 11/126:00 amPWM - DSM
2 stops11h 19mDelta
Deal found 9/11$262
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/306:00 amDSM - PWM
1 stop4h 44mAmerican Airlines
Fri 10/35:20 pmPWM - DSM
1 stop7h 25mAmerican Airlines
Deal found 9/11$273
This United Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3011:31 amDSM - PWM
2 stops10h 42mUnited Airlines
Fri 10/34:57 pmPWM - DSM
1 stop5h 53mUnited Airlines
Deal found 9/11$278
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/273:15 pmDSM - PWM
1 stop6h 54mDelta
Wed 10/2911:30 amPWM - DSM
2 stops10h 05mDelta
Deal found 9/11$292
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/44:20 pmDSM - PWM
1 stop5h 23mAmerican Airlines
Sat 10/115:12 pmPWM - DSM
1 stop5h 44mAmerican Airlines
Deal found 9/10$318
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:50 pmDSM - PWM
1 stop6h 55mAmerican Airlines
Tue 9/306:00 amPWM - DSM
1 stop8h 05mAmerican Airlines
Deal found 9/11$348

Cheapflights Fare Finder

 
Customize your flight search to find flights from Des Moines to Portland that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Des Moines to Portland that are best for you.

Fly from

Des Moines

Fly to

Portland

Route

Depart

Return

Price

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Wed 11/5

3:18 pm-9:35 pm

1 stop5h 17m

Portland

Wed 11/12

5:43 am-12:24 pm

1 stop7h 41m

$229

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Sat 10/18

12:52 pm-9:44 pm

1 stop7h 52m

Portland

Wed 10/22

4:57 pm-9:50 pm

1 stop5h 53m

$229

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Wed 10/1

11:17 am-12:34 am

2 stops12h 17m

Portland

Wed 10/8

6:00 am-1:28 pm

1 stop8h 28m

$262

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Wed 11/5

10:00 am-4:03 pm

1 stop5h 03m

Portland

Wed 11/12

6:00 am-4:19 pm

2 stops11h 19m

$262

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Mon 10/27

3:56 pm-11:51 pm

1 stop6h 55m

Portland

Wed 10/29

5:21 pm-11:59 pm

1 stop7h 38m

$273

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 9/30

6:00 am-11:44 am

1 stop4h 44m

Portland

Fri 10/3

5:20 pm-11:45 pm

1 stop7h 25m

$273

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 9/30

3:25 pm-11:59 pm

2 stops7h 34m

Portland

Fri 10/3

8:00 am-5:24 pm

2 stops10h 24m

$319

Des MoinesPortland

DSM - PWM

DSMPWM

Des Moines

Tue 9/30

1:00 pm-9:44 pm

1 stop7h 44m

$115

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Best time to book a flight from Des Moines to Portland

Have a flexible travel schedule? Discover the best time to fly to Portland from Des Moines with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Portland

How far ahead should I book a flight from Des Moines to Portland, Maine?

Use this chart to determine the optimal time to book a round-trip flight from Des Moines to Portland. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Des Moines to Portland, Maine, you should look to book at least 43 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Des Moines to Portland, Maine?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Portland, Maine (average of $296). Flying from Des Moines to Portland, Maine in July is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Portland

Get insights into the airlines that provide service to Portland. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Portland. Reviews last updated September 11, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Des Moines to Portland by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Portland. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Des Moines to Portland, Maine?

    For as low as $229, American Airlines can have you in Portland, Maine from Des Moines in 5h 17m. Des Moines and Portland, Maine are separated by a distance of 1192 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Des Moines to Portland, Maine round-trip?

    According to our current data, Delta ($276), American Airlines ($296), and United Airlines ($321) offers the cheapest pricing from Des Moines to Portland, Maine. These flights start at 36% lower than the current average price 3 months from now.

  • Can I find deals for flights from Des Moines to Portland that include hotel bookings?

    Yes. In addition to deals on Des Moines to Portland flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Des Moines to Portland?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Portland.

  • Can I find deals for business class flights from Des Moines to Portland?

    Yes. Cheapflights offers flight deals from Des Moines to Portland by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Des Moines to Portland, Maine?

    Currently, January is the cheapest month in which you can book a flight from Des Moines to Portland, Maine (average of $296). Flying from Des Moines to Portland, Maine in July is currently the most expensive (average of $394). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Portland?

Book flights to Portland if you plan to visit one of these locations
Brunswick
North Conway
Auburn
Conway
Lewiston

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Des Moines to Portland

Discover the top 3 airlines that operate flights from Des Moines to Portland. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$276Average$480FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$296Average$418FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$321Average$472FlexibilityNo cancel feeOn-time69%

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