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$126+ Cheap flights from Knoxville (TYS) to Columbus (CMH)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — CMH
Nov 27 — Dec 41
Thu 11/27
Thu 12/4
1 adult, Economy
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Find flight deals from Knoxville to Columbus

Cheapest flights from Knoxville to Columbus
Explore the most affordable flight options available from Knoxville to Columbus. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 28, 2025.

This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amTYS - CMH
1 stop6h 00mAmerican Airlines
Wed 12/318:23 amCMH - TYS
1 stop4h 29mAmerican Airlines
Deal found 10/26$239
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:12 amTYS - CMH
1 stop5h 34mAmerican Airlines
Thu 11/278:00 amCMH - TYS
1 stop4h 42mAmerican Airlines
Deal found 10/27$249
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:50 pmTYS - CMH
1 stop4h 22mDelta
Sat 12/612:26 pmCMH - TYS
1 stop6h 32mDelta
Deal found 10/28$251
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/124:32 pmTYS - CMH
1 stop6h 38mMultiple Airlines
Sun 11/169:42 amCMH - TYS
1 stop28h 15mMultiple Airlines
Deal found 10/28$268
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/205:42 amTYS - CMH
1 stop6h 25mAmerican Airlines
Sat 1/1712:19 pmCMH - TYS
1 stop3h 58mAmerican Airlines
Deal found 10/26$278
This Mytrip deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:53 amTYS - CMH
1 stop13h 58mMultiple Airlines
Tue 12/23:08 pmCMH - TYS
2 stops20h 55mMultiple Airlines
Deal found 10/28$291
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/143:41 pmTYS - CMH
1 stop7h 29mMultiple Airlines
Sun 11/169:42 amCMH - TYS
1 stop28h 15mMultiple Airlines
Deal found 10/28$296
This American Airlines deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/265:42 amTYS - CMH
1 stop6h 27mAmerican Airlines
Thu 1/16:35 amCMH - TYS
1 stop4h 15mAmerican Airlines
Deal found 10/26$298
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:35 amTYS - CMH
1 stop3h 20mDelta
Tue 12/26:20 amCMH - TYS
1 stop5h 27mDelta
Deal found 10/28$299

Cheap flight deals from Knoxville to Columbus

Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Columbus (CMH). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 28, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$239
(American Airlines)

One-way from

$126
(Delta)

Popular in

December

Cheapest in

January

Average price

$298
Provider with most accurate pricing for Knoxville McGhee Tyson-Columbus flight deals.
Search Deals
Provider most trusted by Cheapflights users for Knoxville McGhee Tyson-Columbus flights.
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From Knoxville McGhee Tyson to Columbus
Search Deals
One-way flight from Knoxville McGhee Tyson to Columbus
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Knoxville to Columbus that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
Use the filters below to find and compare flights from Knoxville to Columbus Airport that are best for you.

Fly from

Knoxville

Fly to

Columbus

Route

Depart

Return

Price

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Thu 12/25

7:00 am-1:00 pm

1 stop6h 00m

Columbus

Wed 12/31

8:23 am-12:52 pm

1 stop4h 29m

$239

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Mon 11/24

6:12 am-11:46 am

1 stop5h 34m

Columbus

Thu 11/27

8:00 am-12:42 pm

1 stop4h 42m

$249

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 12/3

12:50 pm-5:12 pm

1 stop4h 22m

Columbus

Sat 12/6

12:26 pm-6:58 pm

1 stop6h 32m

$251

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 11/12

4:32 pm-11:10 pm

1 stop6h 38m

Columbus

Sun 11/16

9:42 am-1:57 pm

1 stop28h 15m

$268

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 12/20

5:42 am-12:07 pm

1 stop6h 25m

Columbus

Sat 1/17

12:19 pm-4:17 pm

1 stop3h 58m

$278

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 11/25

9:53 am-11:51 pm

1 stop13h 58m

Columbus

Tue 12/2

3:08 pm-12:03 pm

2 stops20h 55m

$291

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Fri 12/26

5:42 am-12:09 pm

1 stop6h 27m

Columbus

Thu 1/1

6:35 am-10:50 am

1 stop4h 15m

$298

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Tue 11/25

5:35 am-8:55 am

1 stop3h 20m

Columbus

Tue 12/2

6:20 am-11:47 am

1 stop5h 27m

$299

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Wed 11/19

7:39 am-1:23 pm

1 stop5h 44m

$126

KnoxvilleColumbus

TYS - CMH

TYSCMH

Knoxville McGhee Tyson

Sat 11/15

8:45 am-12:43 pm

1 stop3h 58m

$126

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 16 results
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Compare providers for flights from Knoxville to Columbus

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Columbus in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Knoxville-Columbus Airport flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Knoxville-Columbus Airport flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Knoxville-Columbus Airport flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Knoxville-Columbus Airport flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Columbus Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Knoxville to Columbus

Have a flexible travel schedule? Discover the best time to fly to Columbus from Knoxville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Knoxville to Columbus Airport

What is the cheapest month to book a flight from Knoxville to Columbus Airport?

Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus Airport (average of $171). Flying from Knoxville to Columbus Airport in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from TYS to CMH?

Find hourly flight availability from Knoxville to Columbus. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 28, 2025.

It’s typically best to fly out from Knoxville to Columbus Airport at noon. Doing so could potentially save you 52% on the flight price compared to flying in the afternoon, which is usually more expensive.

Reviews of airlines servicing Columbus

Get insights into the airlines that provide service to Columbus. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Columbus. Reviews last updated October 28, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Knoxville to Columbus Airport by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
9,001 reviews
Delta
7.9
Good
7,994 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Food

7.3

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Knoxville to Columbus. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Knoxville to Columbus?

    Knoxville McGhee Tyson (TYS), located 11.3 mi from the city center, is the airport you fly out of when you book flights from Knoxville to Columbus. 3 airlines have flights from McGhee Tyson to Columbus on a regular basis. Booking flights from Knoxville McGhee Tyson to Columbus should not be difficult; the airport handles an average of 0 outbound flights to Columbus per day.

  • How long is the flight from Knoxville to Columbus Airport?

    For as low as $251, American Airlines can have you in Columbus Airport from Knoxville in 4h 22m. The distance from Knoxville to Columbus Airport is about 296 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from Knoxville to Columbus Airport round-trip?

    Flying on Delta is currently your cheapest option to Columbus Airport, with prices starting at $218. Additional round-trip tickets that might be worth considering are offered by American Airlines and United Airlines, with the lowest prices starting at $223 and $298, respectively. You may be able to fly from Knoxville to Columbus Airport for 35% less than the average price by searching for these airlines.

  • Can I find deals for flights from Knoxville to Columbus that include hotel bookings?

    Yes. In addition to deals on Knoxville to Columbus flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Knoxville to Columbus?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Knoxville to Columbus.

  • Can I find deals for business class flights from Knoxville to Columbus?

    Yes. Cheapflights offers flight deals from Knoxville to Columbus by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Knoxville to Columbus Airport?

    Currently, September is the cheapest month in which you can book a flight from Knoxville to Columbus Airport (average of $171). Flying from Knoxville to Columbus Airport in December is currently the most expensive (average of $258). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Columbus Airport?

Book flights to Columbus Airport if you plan to visit one of these locations
Westerville
Reynoldsburg
Logan
Marysville
Grove City
Gahanna
Lancaster
Hilliard

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Alternative routes for Knoxville to Columbus

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Knoxville to Columbus

Discover the top 3 airlines that operate flights from Knoxville to Columbus. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 28, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$218Average$318FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$223Average$293FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$298Average$539FlexibilityNo cancel feeOn-time69%

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