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Panama

$242+ Cheap flights from San Antonio (SAT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/17. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
Feb 27 — Mar 61
Fri 2/27
Fri 3/6
1 adult, Economy
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Cheap flight deals from San Antonio to Panama

Cheapest flights from San Antonio to Panama
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 28, 2026.

This Avianca deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/162:15 pm
SAT
-
PTY
2 stops11h 40m
Multiple Airlines
Sun 8/235:30 am
PTY
-
SAT
2 stops10h 03m
Multiple Airlines
Deal found 1/27$506
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/2011:46 am
SAT
-
PTY
1 stop6h 51m
United Airlines
Wed 4/223:30 pm
PTY
-
SAT
1 stop7h 29m
United Airlines
Deal found 1/27$521
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:42 pm
SAT
-
PTY
2 stops18h 54m
American Airlines
Tue 4/211:49 pm
PTY
-
SAT
1 stop9h 13m
American Airlines
Deal found 1/26$525
This Delta deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:33 pm
SAT
-
PTY
1 stop18h 29m
Delta
Mon 4/272:27 pm
PTY
-
SAT
1 stop19h 19m
Delta
Deal found 1/27$531
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/1811:46 am
SAT
-
PTY
1 stop6h 51m
United Airlines
Thu 4/237:55 am
PTY
-
SAT
1 stop7h 51m
United Airlines
Deal found 1/27$541
This American Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:25 pm
SAT
-
PTY
2 stops18h 15m
American Airlines
Thu 3/261:40 pm
PTY
-
SAT
2 stops18h 43m
American Airlines
Deal found 1/27$545
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/164:20 pm
SAT
-
PTY
1 stop26h 17m
United Airlines
Sun 8/233:20 pm
PTY
-
SAT
1 stop7h 13m
United Airlines
Deal found 1/27$547
This United Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/155:50 pm
SAT
-
PTY
1 stop24h 48m
United Airlines
Thu 3/193:41 pm
PTY
-
SAT
1 stop7h 16m
United Airlines
Deal found 1/26$548
This United Airlines deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/187:40 am
SAT
-
PTY
1 stop8h 32m
United Airlines
Fri 4/243:30 pm
PTY
-
SAT
1 stop7h 29m
United Airlines
Deal found 1/27$561
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/144:30 pm
SAT
-
PTY
2 stops20h 06m
American Airlines
Sat 11/212:43 pm
PTY
-
SAT
2 stops21h 10m
American Airlines
Deal found 1/26$565
This KAYAK deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:00 pm
SAT
-
PTY
1 stop23h 37m
Copa Airlines
Fri 7/107:55 am
PTY
-
SAT
1 stop13h 18m
Copa Airlines
Deal found 1/27$566

Find flight deals from San Antonio to Panama

Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated January 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$506
(Avianca)

One-way from

$242
(Kiwi.com)

Popular in

December

Cheapest in

May

Average price

$622
Provider with most accurate pricing for San Antonio-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Panama City Tocumen Intl flights.
Search Deals
From San Antonio to Panama
Search Deals
One-way flight from San Antonio to Panama
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($85 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.

Fly from

San Antonio

Fly to

Panama

Route

Depart

Return

Price

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Thu 4/16

11:46 am-6:37 pm

1 stop6h 51m

Panama City Tocumen Intl

Tue 4/21

10:00 am-9:03 pm

1 stop11h 03m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 4/21

5:20 am-1:02 pm

1 stop7h 42m

Panama City Tocumen Intl

Thu 4/23

2:27 pm-12:34 am

1 stop10h 07m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 4/20

11:46 am-6:37 pm

1 stop6h 51m

Panama City Tocumen Intl

Mon 4/27

7:55 am-7:48 pm

1 stop11h 53m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Sun 4/19

6:33 pm-1:02 pm

1 stop18h 29m

Panama City Tocumen Intl

Thu 4/23

2:27 pm-12:34 am

1 stop10h 07m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 4/21

7:40 am-4:12 pm

1 stop8h 32m

Panama City Tocumen Intl

Tue 4/28

10:00 am-10:59 pm

1 stop12h 59m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 4/21

7:40 am-4:12 pm

1 stop8h 32m

Panama City Tocumen Intl

Mon 4/27

7:55 am-9:03 pm

1 stop13h 08m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Mon 4/20

5:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

Tue 4/28

10:00 am-9:03 pm

1 stop11h 03m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Tue 4/21

5:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

Wed 4/22

3:30 pm-10:59 pm

1 stop7h 29m

$521

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Thu 4/16

5:42 pm-12:36 pm

2 stops18h 54m

Panama City Tocumen Intl

Tue 4/21

1:49 pm-11:05 am

2 stops21h 16m

$525

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

Sun 4/19

6:33 pm-1:02 pm

1 stop18h 29m

Panama City Tocumen Intl

Mon 4/27

2:27 pm-9:46 am

1 stop19h 19m

$531

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/26

Showing 1-10 of 21 results
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Best time to book a flight from San Antonio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Panama

What is the cheapest month to book a flight from San Antonio to Panama?

Currently, July is the cheapest month in which you can book a flight from San Antonio to Panama (average of $343). Flying from San Antonio to Panama in December is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated January 28, 2026.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,124 reviews
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,212 reviews
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,201 reviews
Delta
7.9
Good
8,124 reviews

Food

7.2

Entertainment

7.8

Overall

7.9

Crew

8.5

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to Panama?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to Panama from San Antonio.

  • How long is the flight from San Antonio to Panama?

    Departing from San Antonio to Panama will take you 6h 51m. There are 1876 mi between San Antonio and Panama. This flight may include one or multiple stops.

  • Can I find deals for flights from San Antonio to Panama that include hotel bookings?

    Yes. In addition to deals on San Antonio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Panama.

  • Can I find deals for business class flights from San Antonio to Panama?

    Yes. Cheapflights offers flight deals from San Antonio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Panama?

    Currently, July is the cheapest month in which you can book a flight from San Antonio to Panama (average of $343). Flying from San Antonio to Panama in December is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for San Antonio to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from San Antonio to Panama

Discover the top 3 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$226Average$629FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$739FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$479Average$606FlexibilityNo cancel feeOn-time69%

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