$255+ Cheap flights from San Antonio (SAT) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/30. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
Apr 11 — Apr 181
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Panama with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from San Antonio to PanamaExplore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 12, 2026.
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:25 pm
SAT
- PTY
2 stops11h 30m
Multiple Airlines
Wed 5/275:30 am
PTY
- SAT
2 stops10h 09m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$521
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Wed 4/295:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:40 am
SAT
- PTY
1 stop8h 57m
United Airlines
Thu 5/77:55 am
PTY
- SAT
1 stop9h 50m
United Airlines
Deal found 3/8![United Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:25 am
SAT
- PTY
1 stop7h 25m
Delta
Mon 6/12:15 pm
PTY
- SAT
1 stop8h 16m
Delta
Deal found 3/9![Delta logo]()
$571
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:45 pm
SAT
- PTY
2 stops19h 01m
American Airlines
Tue 6/21:14 pm
PTY
- SAT
1 stop10h 48m
American Airlines
Deal found 3/8![American Airlines logo]()
$575
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:19 pm
SAT
- PTY
2 stops23h 27m
American Airlines
Thu 5/71:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Deal found 3/9![American Airlines logo]()
$577
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Wed 4/225:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$578
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:35 am
SAT
- PTY
1 stop11h 02m
United Airlines
Thu 9/1010:00 am
PTY
- SAT
1 stop12h 38m
United Airlines
Deal found 3/10![United Airlines logo]()
$582
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Fri 4/175:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/57:35 am
SAT
- PTY
1 stop11h 02m
United Airlines
Wed 5/277:55 am
PTY
- SAT
1 stop7h 44m
United Airlines
Deal found 3/9![United Airlines logo]()
$591
Best flights from San Antonio to PanamaDiscover carefully curated flight deals from San Antonio to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
Discover carefully curated flight deals from San Antonio to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 12, 2026.
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:35 am
SAT
- PTY
1 stop11h 02m
United Airlines
Thu 9/1010:00 am
PTY
- SAT
1 stop11h 16m
United Airlines
Deal found 3/8![United Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/185:25 am
SAT
- PTY
1 stop7h 25m
Delta
Mon 6/12:15 pm
PTY
- SAT
1 stop10h 29m
Delta
Deal found 3/8![Delta logo]()
$571
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/85:30 am
SAT
- PTY
1 stop8h 44m
United Airlines
Thu 6/1810:00 am
PTY
- SAT
1 stop11h 25m
United Airlines
Deal found 3/8![United Airlines logo]()
$571
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/117:35 am
SAT
- PTY
1 stop8h 37m
United Airlines
Wed 5/137:55 am
PTY
- SAT
1 stop13h 25m
United Airlines
Deal found 3/8![United Airlines logo]()
$571
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:43 am
SAT
- PTY
1 stop8h 29m
United Airlines
Mon 6/293:30 pm
PTY
- SAT
1 stop7h 12m
United Airlines
Deal found 3/9![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 3/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:30 am
SAT
- PTY
1 stop13h 07m
United Airlines
Thu 7/167:55 am
PTY
- SAT
1 stop13h 18m
United Airlines
Deal found 3/12![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/59:37 am
SAT
- PTY
1 stop6h 35m
United Airlines
Wed 7/153:30 pm
PTY
- SAT
1 stop16h 57m
United Airlines
Deal found 3/8![United Airlines logo]()
$591
Last-minute flights from San Antonio to PanamaDiscover last-minute flight deals from San Antonio to Panama. Data last updated March 12, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Panama. Data last updated March 12, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/188:37 pm
SAT
- PTY
2 stops17h 23m
Multiple Airlines
Thu 4/23:00 pm
PTY
- SAT
1 stop25h 20m
Multiple Airlines
Deal found 3/10![Multiple Airlines logo]()
$618
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3011:46 am
SAT
- PTY
1 stop6h 51m
United Airlines
Tue 6/303:30 pm
PTY
- SAT
1 stop7h 12m
United Airlines
Deal found 3/9![United Airlines logo]()
$611
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/92:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Fri 4/175:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$587
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Wed 4/225:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$578
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:42 pm
SAT
- PTY
2 stops19h 04m
American Airlines
Wed 4/221:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Deal found 3/8![American Airlines logo]()
$617
This Avianca deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/222:14 pm
SAT
- PTY
2 stops11h 41m
Multiple Airlines
Wed 4/295:30 am
PTY
- SAT
2 stops10h 16m
Multiple Airlines
Deal found 3/8![Multiple Airlines logo]()
$559
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:30 am
SAT
- PTY
1 stop10h 42m
United Airlines
Wed 4/2910:00 am
PTY
- SAT
1 stop12h 59m
United Airlines
Deal found 3/8![United Airlines logo]()
$591
This United Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:40 am
SAT
- PTY
1 stop8h 57m
United Airlines
Thu 5/77:55 am
PTY
- SAT
1 stop9h 50m
United Airlines
Deal found 3/8![United Airlines logo]()
$562
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:20 am
SAT
- PTY
1 stop7h 42m
Delta
Thu 5/72:15 pm
PTY
- SAT
1 stop8h 16m
Delta
Deal found 3/9![Delta logo]()
$571
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/281:19 pm
SAT
- PTY
2 stops23h 27m
American Airlines
Thu 5/71:49 pm
PTY
- SAT
1 stop9h 26m
American Airlines
Deal found 3/9![American Airlines logo]()
$577
One-way flights from San Antonio to PanamaSearch for one-way flight options from San Antonio to Panama. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
Search for one-way flight options from San Antonio to Panama. Find affordable one-way fares based on user searches. Data last updated March 12, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3010:05 am
SAT
- PTY
3 stops52h 10m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$255
This Delta deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:10 am
SAT
- PTY
1 stop7h 53m
Delta
Deal found 3/9![Delta logo]()
$303
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/49:40 am
SAT
- PTY
1 stop6h 32m
United Airlines
Deal found 3/9![United Airlines logo]()
$323
This Mytrip deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/41:06 pm
SAT
- PTY
2 stops24h 24m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$378
Find flight deals from San Antonio to Panama
Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated March 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $521 (Avianca) |
One-way from | $255 (Kiwi.com) |
Popular in | December |
Cheapest in | April |
Average price | $660 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Tue 9/1
7:35 am-6:37 pm
1 stop11h 02m
Panama City Tocumen Intl
Thu 9/10
10:00 am-9:16 pm
1 stop11h 16m
$562
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 5/18
5:25 am-12:50 pm
1 stop7h 25m
Panama City Tocumen Intl
Mon 6/1
2:15 pm-12:44 am
1 stop10h 29m
$571
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 6/8
5:30 am-2:14 pm
1 stop8h 44m
Panama City Tocumen Intl
Thu 6/18
10:00 am-9:25 pm
1 stop11h 25m
$571
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 5/11
7:35 am-4:12 pm
1 stop8h 37m
Panama City Tocumen Intl
Wed 5/13
7:55 am-9:20 pm
1 stop13h 25m
$571
Quickest round-trip
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Wed 6/17
7:43 am-4:12 pm
1 stop8h 29m
Panama City Tocumen Intl
Mon 6/29
3:30 pm-10:42 pm
1 stop7h 12m
$591
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 7/6
5:30 am-6:37 pm
1 stop13h 07m
Panama City Tocumen Intl
Thu 7/16
7:55 am-9:13 pm
1 stop13h 18m
$591
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Sun 7/5
9:37 am-4:12 pm
1 stop6h 35m
Panama City Tocumen Intl
Wed 7/15
3:30 pm-8:27 am
1 stop16h 57m
$591
Cheapest one-way
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 3/30
1:22 pm-1:05 am
2 stops35h 43m
$283
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Mon 3/30
5:10 am-1:03 pm
1 stop7h 53m
$303
Quickest one-way
San AntonioPanama City
SAT - PTY
SATPTY
San Antonio
Sat 4/4
9:40 am-4:12 pm
1 stop6h 32m
$323
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from San Antonio to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
SAT-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Panama
SAT-PA0
SAT-PTY
What is the cheapest month to book a flight from San Antonio to Panama?
Currently, February is the cheapest month in which you can book a flight from San Antonio to Panama (average of $237). Flying from San Antonio to Panama in December is currently the most expensive (average of $468). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 12, 2026.
See what other customers who have flown with United Airlines and American Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.6
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Food
6.6
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Food
6.6
Boarding
7.7
Crew
8.1
Overall
7.4
Entertainment
7.1
Comfort
7.3
Reviews
1 / 20
10.0
ExcellentDane,Jan 2026
TYS - IAD
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for San Antonio to Panama
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Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
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San Antonio and Panama flights
Browse other San Antonio and Panama flight options. Last updated on March 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 2 airlines flying from San Antonio to Panama
Discover the top 2 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$467 | Average$779 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$469 | Average$605 | FlexibilityNo cancel fee | On-time69% |