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$237+ Cheap flights from San Antonio (SAT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — PTY
nov. 28 — dec. 51
vr 11/28
vr 12/5
1 adult, Economy
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Cheap flight deals from San Antonio to Panama

Keep the following information in mind while searching for San Antonio to Panama flight deals. Data was last updated oktober 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$500
(United Airlines)

One-way from

$237
(Delta)

Popular in

December

Cheapest in

May

Average price

$559
Provider with most accurate pricing for San Antonio-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for San Antonio-Panama City Tocumen Intl flights.
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From San Antonio to Panama
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One-way flight from San Antonio to Panama
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Highest demand for flights based on searches. 6% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from San Antonio to Panama

Cheapest flights from San Antonio to Panama
Explore the most affordable flight options available from San Antonio to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on oktober 29, 2025.

This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 12/115:20 amSAT - PTY
1 stop13h 18mUnited Airlines
do 12/184:41 pmPTY - SAT
1 stop7h 07mUnited Airlines
Deal found 10/27$520
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
do 12/187:30 pmSAT - PTY
1 stop18h 15mUnited Airlines
zo 12/2111:35 amPTY - SAT
1 stop26h 36mUnited Airlines
Deal found 10/29$553
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 12/66:05 pmSAT - PTY
2 stops18h 42mAmerican Airlines
vr 1/164:50 pmPTY - SAT
2 stops19h 18mAmerican Airlines
Deal found 10/27$556
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 12/67:47 amSAT - PTY
1 stop10h 51mUnited Airlines
vr 1/164:41 pmPTY - SAT
1 stop17h 00mUnited Airlines
Deal found 10/27$560
This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 12/267:30 pmSAT - PTY
1 stop20h 37mUnited Airlines
vr 1/94:41 pmPTY - SAT
1 stop17h 00mUnited Airlines
Deal found 10/28$566
This United Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
zo 11/232:14 pmSAT - PTY
1 stop23h 31mUnited Airlines
do 11/274:41 pmPTY - SAT
1 stop26h 06mUnited Airlines
Deal found 10/27$573
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 12/125:20 amSAT - PTY
1 stop9h 22mAmerican Airlines
vr 12/192:53 pmPTY - SAT
2 stops19h 26mAmerican Airlines
Deal found 10/28$574
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
za 12/63:00 pmSAT - PTY
2 stops23h 42mAmerican Airlines
ma 1/124:50 pmPTY - SAT
2 stops22h 26mAmerican Airlines
Deal found 10/28$576
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ma 12/85:20 amSAT - PTY
1 stop9h 22mAmerican Airlines
ma 1/124:50 pmPTY - SAT
2 stops20h 28mAmerican Airlines
Deal found 10/27$577
This deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vr 11/147:40 amSAT - PTY
1 stop10h 58mUnited Airlines
di 11/254:41 pmPTY - SAT
1 stop7h 15mUnited Airlines
Deal found 10/27$580
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wo 11/125:30 amSAT - PTY
1 stop8h 15mUnited Airlines
za 11/158:55 amPTY - SAT
1 stop13h 25mUnited Airlines
Deal found 10/29$600

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated oktober 29, 2025.
Use the filters below to find and compare flights from San Antonio to Panama that are best for you.

Fly from

San Antonio

Fly to

Panama

Route

Depart

Return

Price

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

ma 2/23

7:40 am-2:45 pm

1 stop6h 05m

Panama City Tocumen Intl

ma 3/2

8:55 am-5:50 pm

1 stop9h 55m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

ma 3/9

5:30 am-12:55 pm

1 stop7h 25m

Panama City Tocumen Intl

wo 3/18

2:20 pm-12:14 am

1 stop9h 54m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

do 2/19

5:20 am-1:40 pm

1 stop7h 20m

Panama City Tocumen Intl

do 2/26

2:52 pm-11:26 pm

1 stop9h 34m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

do 3/5

5:00 am-5:07 pm

1 stop11h 07m

Panama City Tocumen Intl

ma 3/16

11:35 am-10:33 pm

1 stop10h 58m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

ma 4/6

5:30 am-12:55 pm

1 stop7h 25m

Panama City Tocumen Intl

do 4/9

2:20 pm-12:14 am

1 stop9h 54m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

wo 4/1

5:31 am-2:20 pm

1 stop8h 49m

Panama City Tocumen Intl

vr 4/10

1:55 pm-11:07 pm

1 stop9h 12m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

wo 3/11

12:24 pm-6:38 pm

1 stop6h 14m

Panama City Tocumen Intl

ma 3/16

7:55 am-9:23 pm

1 stop13h 28m

$500

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

ma 3/9

10:00 am-4:07 pm

1 stop6h 07m

Panama City Tocumen Intl

vr 3/13

7:55 am-3:43 pm

1 stop7h 48m

$520

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

wo 11/26

3:00 pm-1:43 pm

2 stops21h 43m

$237

San AntonioPanama City

SAT - PTY

SATPTY

San Antonio

wo 11/26

5:15 am-2:12 pm

1 stop7h 57m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 18 results
1
2

Best time to book a flight from San Antonio to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Panama

What is the cheapest month to book a flight from San Antonio to Panama?

Currently, November is the cheapest month in which you can book a flight from San Antonio to Panama (average of $249). Flying from San Antonio to Panama in December is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to PA?

Find hourly flight availability from San Antonio to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated oktober 29, 2025.

When flying from San Antonio to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 71% versus a flight in the morning.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated oktober 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from San Antonio to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,992 reviews
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,999 reviews
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,992 reviews

Entertainment

7.9

Boarding

8.2

Food

7.3

Overall

7.9

Comfort

7.9

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from San Antonio to Panama?

    Located just 7.6 mi from the city center, San Antonio (SAT) is the airport most travelers will use when flying to Panama from San Antonio.

  • How long is the flight from San Antonio to Panama?

    Departing from San Antonio to Panama will take you 6h 05m. There are 1876 mi between San Antonio and Panama. This flight may include one or multiple stops.

  • Can I find deals for flights from San Antonio to Panama that include hotel bookings?

    Yes. In addition to deals on San Antonio to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Panama.

  • Can I find deals for business class flights from San Antonio to Panama?

    Yes. Cheapflights offers flight deals from San Antonio to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Panama?

    Currently, November is the cheapest month in which you can book a flight from San Antonio to Panama (average of $249). Flying from San Antonio to Panama in December is currently the most expensive (average of $454). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from San Antonio to Panama

Discover the top 3 airlines that operate flights from San Antonio to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated oktober 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$277Average$639FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$467Average$739FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$479Average$598FlexibilityNo cancel feeOn-time69%

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