Panama

$242+ Cheap flights from Roanoke (ROA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
jul. 7 — jul. 141
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Cheap flight deals from Roanoke to Panama

Keep the following information in mind while searching for Roanoke to Panama flight deals. Data was last updated julio 2, 2025.

Round-trip from

$475
(United Airlines)

One-way from

$242
(United Airlines)

Popular in

December

Cheapest in

October

Average price

$477
From Roanoke to Panama
One-way flight from Roanoke to Panama
Highest demand for flights based on searches. 9% potential increase in price ($68 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Average for round-trip flights in July 2025

Find flight deals from Roanoke to Panama

Cheapest flights from Roanoke to Panama
Explore the most affordable flight options available from Roanoke to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on julio 2, 2025.

This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 8/155:42 pmROA - PTY
2 stops23h 30mUnited Airlines
vie. 8/223:30 pmPTY - ROA
2 stops17h 36mUnited Airlines
Deal found 7/1$475
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 7/45:00 amROA - PTY
2 stops10h 25mAmerican Airlines
vie. 7/111:55 pmPTY - ROA
2 stops19h 37mAmerican Airlines
Deal found 6/30$522
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/166:00 amROA - PTY
1 stop7h 50mDelta
sáb. 8/232:05 pmPTY - ROA
1 stop9h 27mDelta
Deal found 7/2$777
This Expedia deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 8/167:50 pmROA - PTY
2 stops39h 35mAvianca
sáb. 8/238:10 pmPTY - ROA
3 stops45h 34mAvianca
Deal found 7/2$941
This United deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 8/136:20 amROA - PTY
2 stops13h 17mMultiple Airlines
sáb. 8/163:20 amPTY - ROA
2 stops14h 26mMultiple Airlines
Deal found 7/1$1,145

Cheapflights Fare Finder

Customize your flight search to find flights from Roanoke to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 2, 2025.
Use the filters below to find and compare flights from Roanoke to Panama that are best for you.

Fly from

Roanoke

Fly to

Panama

Route

Depart

Return

Price

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

vie. 8/15

5:42 pm-4:12 pm

2 stops23h 30m

Panama City Tocumen Intl

vie. 8/22

3:30 pm-10:06 am

2 stops17h 36m

$475

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

sáb. 8/16

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

sáb. 8/23

2:05 pm-12:32 am

1 stop9h 27m

$777

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

sáb. 8/16

7:50 pm-10:25 am

2 stops39h 35m

Panama City Tocumen Intl

sáb. 8/23

8:10 pm-6:44 pm

3 stops45h 34m

$941

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

mié. 8/13

6:20 am-6:37 pm

2 stops13h 17m

Panama City Tocumen Intl

sáb. 8/16

3:20 am-6:46 pm

2 stops14h 26m

$1,145

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

lun. 9/1

7:35 pm-6:37 pm

2 stops24h 02m

$242

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/30

Best time to book a flight from Roanoke to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama

What is the cheapest month to book a flight from Roanoke to Panama?

Currently, October is the cheapest month in which you can book a flight from Roanoke to Panama (average of $478). Flying from Roanoke to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to PA?

Find hourly flight availability from Roanoke to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated julio 2, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated julio 2, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and Avianca from Roanoke to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Entertainment

7.9

Food

7.3

Overall

8.0

Boarding

8.2

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Roanoke to Panama?

    For a flight from Roanoke to Panama, you will be flying from Roanoke. Roanoke (ROA) is just 4.2 mi from the center of the city.

  • Can I find deals for flights from Roanoke to Panama that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama.

  • Can I find deals for business class flights from Roanoke to Panama?

    Yes. Cheapflights offers flight deals from Roanoke to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Panama?

    Currently, October is the cheapest month in which you can book a flight from Roanoke to Panama (average of $478). Flying from Roanoke to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Roanoke to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Roanoke to Panama

Discover the top airline that operate flights from Roanoke to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated julio 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$397Average$673FlexibilityNo cancel feeOn-timeN/A

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