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$522+ Cheap flights from Roanoke (ROA) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/11. Fares are subject to change and may not be available on all flights or dates of travel.
ROA — PTY
ago. 25 — sep. 11
lun. 8/25
lun. 9/1
1 adult, Economy
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Cheap flight deals from Roanoke to Panama

Keep the following information in mind while searching for Roanoke to Panama flight deals. Data was last updated agosto 20, 2025.

Round-trip from

$522
(United Airlines)
From Roanoke to Panama
Search Deals

Find flight deals from Roanoke to Panama

Cheapest flights from Roanoke to Panama
Explore the most affordable flight options available from Roanoke to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 20, 2025.

This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/105:40 pmROA - PTY
2 stops25h 57mUnited Airlines
lun. 9/153:30 pmPTY - ROA
2 stops26h 14mUnited Airlines
Deal found 8/19$522
This Avianca deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/117:35 pmROA - PTY
3 stops18h 00mAvianca
lun. 9/151:30 pmPTY - ROA
3 stops28h 14mAvianca
Deal found 8/19$1,091
This Avianca deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/107:35 pmROA - PTY
2 stops21h 40mAvianca
lun. 9/151:30 pmPTY - ROA
3 stops28h 14mAvianca
Deal found 8/19$1,103
This Avianca deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/107:35 pmROA - PTY
2 stops15h 50mMultiple Airlines
dom. 9/143:20 amPTY - ROA
2 stops14h 24mMultiple Airlines
Deal found 8/19$1,104
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/116:00 amROA - PTY
1 stop7h 55mDelta
lun. 9/152:10 pmPTY - ROA
1 stop9h 15mDelta
Deal found 8/19$1,573
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/106:00 amROA - PTY
1 stop7h 50mDelta
lun. 9/152:10 pmPTY - ROA
1 stop9h 15mDelta
Deal found 8/19$2,424

Cheapflights Fare Finder

 
Customize your flight search to find flights from Roanoke to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 20, 2025.
Use the filters below to find and compare flights from Roanoke to Panama that are best for you.

Fly from

Roanoke

Fly to

Panama

Route

Depart

Return

Price

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

jue. 9/11

6:45 am-6:37 pm

2 stops12h 52m

Panama City Tocumen Intl

lun. 9/15

3:30 pm-2:03 pm

2 stops21h 33m

$522

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

mié. 9/10

5:40 pm-6:37 pm

2 stops25h 57m

Panama City Tocumen Intl

lun. 9/15

3:30 pm-6:44 pm

2 stops26h 14m

$522

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

jue. 9/11

7:35 pm-12:35 pm

3 stops18h 00m

Panama City Tocumen Intl

lun. 9/15

1:30 pm-6:44 pm

3 stops28h 14m

$1,091

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

mié. 9/10

7:35 pm-4:15 pm

2 stops21h 40m

Panama City Tocumen Intl

lun. 9/15

1:30 pm-6:44 pm

3 stops28h 14m

$1,103

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

mié. 9/10

7:35 pm-10:25 am

2 stops15h 50m

Panama City Tocumen Intl

dom. 9/14

3:20 am-6:44 pm

2 stops14h 24m

$1,104

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

jue. 9/11

6:00 am-12:55 pm

1 stop7h 55m

Panama City Tocumen Intl

lun. 9/15

2:10 pm-12:25 am

1 stop9h 15m

$1,573

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

mié. 9/10

6:00 am-12:50 pm

1 stop7h 50m

Panama City Tocumen Intl

lun. 9/15

2:10 pm-12:25 am

1 stop9h 15m

$2,424

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/19

Best time to book a flight from Roanoke to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Roanoke with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama

What is the cheapest month to book a flight from Roanoke to Panama?

Currently, October is the cheapest month in which you can book a flight from Roanoke to Panama (average of $478). Flying from Roanoke to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ROA to PA?

Find hourly flight availability from Roanoke to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 20, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Roanoke to Panama as you normally would.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Roanoke to Panama?

    For a flight from Roanoke to Panama, you will be flying from Roanoke. Roanoke (ROA) is just 4.2 mi from the center of the city.

  • How long is the flight from Roanoke to Panama?

    Airlines like United Airlines and Avianca fly from Roanoke to Panama in about 12h 52m. The time it takes to get you to your destination can typically vary by up to 5h 08m. Airlines will cover a distance of 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Roanoke to Panama that include hotel bookings?

    Yes. In addition to deals on Roanoke to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Roanoke to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama.

  • Can I find deals for business class flights from Roanoke to Panama?

    Yes. Cheapflights offers flight deals from Roanoke to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Roanoke to Panama?

    Currently, October is the cheapest month in which you can book a flight from Roanoke to Panama (average of $478). Flying from Roanoke to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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