How long is the flight from Roanoke to Panama?

Airlines like United Airlines and Delta fly from Roanoke to Panama in about 7h 55m. The time it takes to get you to your destination can typically vary by up to 4h 58m. Airlines will cover a distance of 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What airport do you fly from for flights from Roanoke to Panama?

For a flight from Roanoke to Panama, you will be flying from Roanoke. Roanoke (ROA) is just 4.2 mi from the center of the city.

Can I find deals for flights from Roanoke to Panama that include hotel bookings?

Yes. In addition to deals on Roanoke to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Roanoke to Panama?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama.

Can I find deals for business class flights from Roanoke to Panama?

Yes. Cheapflights offers flight deals from Roanoke to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$205+ Flights from Roanoke to Panama

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Cheap flight deals from Roanoke to Panama

Cheapest flights from Roanoke to Panama
Explore the most affordable flight options available from Roanoke to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Mon 12/156:45 amROA - PTY

2 stops12h 53mUnited Airlines

Mon 12/228:55 amPTY - ROA

2 stops14h 35mUnited Airlines

Deal found 12/9

$568

Thu 12/185:33 pmROA - PTY

2 stops22h 21mAmerican Airlines

Thu 12/252:53 pmPTY - ROA

2 stops17h 49mAmerican Airlines

Deal found 12/11

$801

Wed 12/246:40 amROA - PTY

2 stops12h 58mUnited Airlines

Sun 12/288:55 amPTY - ROA

2 stops25h 21mUnited Airlines

Deal found 12/9

$833

Thu 12/186:00 amROA - PTY

1 stop8h 21mDelta

Thu 12/258:00 amPTY - ROA

1 stop11h 26mDelta

Deal found 12/11

$1,168

Best flights from Roanoke to Panama
Discover carefully curated flight deals from Roanoke to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 12, 2025.

Wed 1/216:45 amROA - PTY

2 stops12h 53mUnited Airlines

Tue 3/34:41 pmPTY - ROA

2 stops17h 32mUnited Airlines

Deal found 12/11

$460

Tue 1/206:00 amROA - PTY

1 stop7h 55mDelta

Wed 3/43:20 pmPTY - ROA

1 stop8h 48mDelta

Deal found 12/11

$476

Thu 1/226:45 amROA - PTY

2 stops12h 53mUnited Airlines

Tue 3/34:41 pmPTY - ROA

2 stops17h 32mUnited Airlines

Deal found 12/11

$460

Mon 1/197:59 pmROA - PTY

1 stop17h 56mDelta

Wed 3/43:20 pmPTY - ROA

2 stops31h 29mDelta

Deal found 12/11

$480

Sun 1/2512:40 pmROA - PTY

2 stops28h 27mUnited Airlines

Wed 3/411:35 amPTY - ROA

2 stops22h 08mUnited Airlines

Deal found 12/11

$460

Fri 1/2312:40 pmROA - PTY

2 stops26h 05mUnited Airlines

Tue 3/34:41 pmPTY - ROA

2 stops21h 31mUnited Airlines

Deal found 12/11

$480

Mon 1/193:39 pmROA - PTY

2 stops23h 06mUnited Airlines

Sun 3/18:55 amPTY - ROA

2 stops25h 18mUnited Airlines

Deal found 12/11

$480

Fri 1/2312:40 pmROA - PTY

2 stops28h 27mUnited Airlines

Mon 3/24:41 pmPTY - ROA

2 stops21h 31mUnited Airlines

Deal found 12/11

$480

Sat 1/3112:40 pmROA - PTY

2 stops26h 05mUnited Airlines

Sun 3/14:41 pmPTY - ROA

2 stops17h 32mUnited Airlines

Deal found 12/10

$480

Fri 1/236:45 amROA - PTY

2 stops13h 17mUnited Airlines

Thu 3/58:55 amPTY - ROA

2 stops25h 18mUnited Airlines

Deal found 12/11

$480

Mon 1/1912:40 pmROA - PTY

2 stops26h 05mUnited Airlines

Thu 1/224:41 pmPTY - ROA

2 stops19h 24mUnited Airlines

Deal found 12/9

$480

Sat 1/245:39 pmROA - PTY

2 stops23h 28mUnited Airlines

Wed 3/411:35 amPTY - ROA

2 stops22h 08mUnited Airlines

Deal found 12/11

$480

Last-minute flights from Roanoke to Panama
Discover last-minute flight deals from Roanoke to Panama. Data last updated December 12, 2025 and is based on user searches.

Mon 1/1912:40 pmROA - PTY

2 stops26h 05mUnited Airlines

Thu 3/54:41 pmPTY - ROA

2 stops17h 32mUnited Airlines

Deal found 12/11

$460

Mon 1/197:59 pmROA - PTY

1 stop17h 56mDelta

Wed 3/43:20 pmPTY - ROA

1 stop8h 48mDelta

Deal found 12/11

$476

Mon 1/1912:40 pmROA - PTY

2 stops26h 05mUnited Airlines

Thu 1/224:41 pmPTY - ROA

2 stops19h 24mUnited Airlines

Deal found 12/9

$480

Mon 1/197:59 pmROA - PTY

1 stop17h 56mDelta

Thu 3/53:20 pmPTY - ROA

2 stops31h 29mDelta

Deal found 12/11

$496

Mon 1/193:39 pmROA - PTY

2 stops25h 28mUnited Airlines

Fri 3/611:35 amPTY - ROA

2 stops22h 08mUnited Airlines

Deal found 12/11

$547

Fri 1/2312:40 pmROA - PTY

2 stops28h 27mUnited Airlines

Sun 3/14:41 pmPTY - ROA

2 stops17h 32mUnited Airlines

Deal found 12/11

$500

Fri 1/237:05 amROA - PTY

2 stops54h 50mDelta

Tue 3/33:20 pmPTY - ROA

1 stop8h 48mDelta

Deal found 12/11

$516

Fri 1/236:45 amROA - PTY

2 stops13h 17mUnited Airlines

Fri 3/611:35 amPTY - ROA

2 stops22h 08mUnited Airlines

Deal found 12/11

$567

Sat 1/243:47 pmROA - PTY

1 stop22h 08mDelta

Tue 3/33:20 pmPTY - ROA

1 stop8h 48mDelta

Deal found 12/11

$503

Sat 1/243:47 pmROA - PTY

1 stop22h 08mDelta

Wed 3/43:20 pmPTY - ROA

2 stops31h 29mDelta

Deal found 12/11

$508

Sat 1/243:47 pmROA - PTY

1 stop22h 08mDelta

Thu 3/53:20 pmPTY - ROA

2 stops31h 29mDelta

Deal found 12/11

$523

Sun 1/256:00 amROA - PTY

2 stops9h 38mAmerican Airlines

Mon 1/264:50 pmPTY - ROA

2 stops19h 19mAmerican Airlines

Deal found 12/11

$522

One-way flights from Roanoke to Panama
Search for one-way flight options from Roanoke to Panama. Find affordable one-way fares based on user searches. Data last updated December 12, 2025.

Tue 1/206:00 amROA - PTY

1 stop7h 55mDelta

Deal found 12/11

$205

Fri 1/236:45 amROA - PTY

2 stops13h 17mUnited Airlines

Deal found 12/11

$225

Sat 1/243:47 pmROA - PTY

1 stop22h 08mDelta

Deal found 12/11

$238

Wed 1/216:00 amROA - PTY

1 stop7h 55mDelta

Deal found 12/11

$327

Fri 1/237:59 pmROA - PTY

1 stop17h 56mDelta

Deal found 12/11

$352

Sat 1/2410:15 amROA - PTY

3 stops28h 40mAvianca

Deal found 12/11

$417

Mon 1/263:53 pmROA - PTY

3 stops56h 47mMultiple Airlines

Deal found 12/11

$419

Tue 1/2010:15 amROA - PTY

3 stops28h 40mAvianca

Deal found 12/11

$427

Fri 1/239:02 amROA - PTY

3 stops35h 17mMultiple Airlines

Deal found 12/11

$497

Thu 1/2210:15 amROA - PTY

3 stops28h 40mAvianca

Deal found 12/11

$507

Wed 1/2110:15 amROA - PTY

3 stops48h 15mAvianca

Deal found 12/11

$535

Sun 1/253:45 pmROA - PTY

3 stops42h 48mMultiple Airlines

Deal found 12/11

$782

Find flight deals from Roanoke to Panama

Most accurate provider	FlightHub 3 stars
Most trusted provider	Expedia 3 stars
Round-trip from	$436 (Delta)
One-way from	$205 (Delta)

Provider with most accurate pricing for Roanoke-Panama City Tocumen Intl flight deals.

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Provider most trusted by Cheapflights users for Roanoke-Panama City Tocumen Intl flights.

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From Roanoke to Panama

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One-way flight from Roanoke to Panama

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Wed 1/21

6:45 am-7:38 pm

2 stops12h 53m

Panama City Tocumen Intl

Tue 3/3

4:41 pm-10:13 am

2 stops17h 32m

$460

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Thu 1/22

6:45 am-7:38 pm

2 stops12h 53m

Panama City Tocumen Intl

Tue 3/3

4:41 pm-10:13 am

2 stops17h 32m

$460

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sun 1/25

12:40 pm-5:07 pm

2 stops28h 27m

Panama City Tocumen Intl

Wed 3/4

11:35 am-9:43 am

2 stops22h 08m

$460

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Tue 1/20

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Wed 3/4

3:20 pm-12:08 am

1 stop8h 48m

$476

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 1/19

7:59 pm-1:55 pm

1 stop17h 56m

Panama City Tocumen Intl

Wed 3/4

3:20 pm-10:49 pm

2 stops31h 29m

$480

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 1/23

12:40 pm-2:45 pm

2 stops26h 05m

Panama City Tocumen Intl

Tue 3/3

4:41 pm-2:12 pm

2 stops21h 31m

$480

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Mon 1/19

3:39 pm-2:45 pm

2 stops23h 06m

Panama City Tocumen Intl

Sun 3/1

8:55 am-10:13 am

2 stops25h 18m

$480

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 1/23

12:40 pm-5:07 pm

2 stops28h 27m

Panama City Tocumen Intl

Mon 3/2

4:41 pm-2:12 pm

2 stops21h 31m

$480

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Sat 1/31

12:40 pm-2:45 pm

2 stops26h 05m

Panama City Tocumen Intl

Sun 3/1

4:41 pm-10:13 am

2 stops17h 32m

$480

RoanokePanama City

ROA - PTY

ROAPTY

Roanoke

Fri 1/23

6:45 am-8:02 pm

2 stops13h 17m

Panama City Tocumen Intl

Thu 3/5

8:55 am-10:13 am

2 stops25h 18m

$480

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Showing 1-10 of 24 results

Best time to book a flight from Roanoke to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Roanoke with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama

What is the cheapest time of day to fly from ROA to PA?

One of the essential ways to save on airfare from Roanoke to Panama is to remain as flexible as possible. Flights that are at noon tend to be the most expensive. A flight in the evening could potentially save you up to 64% on airfare.

Related info for your journey

What airport do you fly from for flights from Roanoke to Panama?
For a flight from Roanoke to Panama, you will be flying from Roanoke. Roanoke (ROA) is just 4.2 mi from the center of the city.
How long is the flight from Roanoke to Panama?
Airlines like United Airlines and Delta fly from Roanoke to Panama in about 7h 55m. The time it takes to get you to your destination can typically vary by up to 4h 58m. Airlines will cover a distance of 1951 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Roanoke to Panama that include hotel bookings?
Yes. In addition to deals on Roanoke to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Roanoke to Panama?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Roanoke to Panama.
Can I find deals for business class flights from Roanoke to Panama?
Yes. Cheapflights offers flight deals from Roanoke to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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$205+ Cheap flights from Roanoke (ROA) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/26. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Roanoke to Panama with Cheapflights

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Cheap flight deals from Roanoke to Panama

Cheapest flights from Roanoke to PanamaExplore the most affordable flight options available from Roanoke to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Explore the most affordable flight options available from Roanoke to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.

Find flight deals from Roanoke to Panama

Keep the following information in mind while searching for Roanoke to Panama flight deals. Data was last updated December 12, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Cheapflights Fare Finder

Use the filters below to find and compare flights from Roanoke to Panama that are best for you.

Best time to book a flight from Roanoke to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Roanoke with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Roanoke to Panama

What is the cheapest time of day to fly from ROA to PA?

Find hourly flight availability from Roanoke to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 12, 2025.

Related info for your journey

Find useful and relevant information for your journey from Roanoke to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Roanoke to Panama?

How long is the flight from Roanoke to Panama?

Can I find deals for flights from Roanoke to Panama that include hotel bookings?

How can I find direct flights from Roanoke to Panama?

Can I find deals for business class flights from Roanoke to Panama?

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Alternative routes for Roanoke to Panama

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Cheapest flights from Roanoke to Panama
Explore the most affordable flight options available from Roanoke to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 12, 2025.