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$153+ Cheap flights from Pueblo, CO to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/22. Fares are subject to change and may not be available on all flights or dates of travel.
COS — PTY
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Cheap flight deals from Pueblo to Panama

Keep the following information in mind while searching for Pueblo to Panama flight deals. Data was last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$548
(Copa Airlines)

One-way from

$153
(Kiwi.com)

Popular in

March

Cheapest in

August

Average price

$688
Provider with most accurate pricing for Denver Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Denver Intl-Panama City Tocumen Intl flights.
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From Pueblo to Panama
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One-way flight from Pueblo to Panama
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Highest demand for flights based on searches. 4% potential increase in price ($29 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($9 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Pueblo to Panama

Cheapest flights from Pueblo to Panama
Explore the most affordable flight options available from Pueblo to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/111:14 pmDEN - PTY
1 stop9h 26mMultiple Airlines
Fri 12/510:25 amPTY - DEN
2 stops14h 34mMultiple Airlines
Deal found 11/18$573
This United Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:02 amDEN - PTY
1 stop10h 05mUnited Airlines
Tue 12/2311:35 amPTY - DEN
1 stop12h 31mUnited Airlines
Deal found 11/18$589
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2810:29 pmDEN - PTY
1 stop28h 51mMultiple Airlines
Sun 1/119:45 amPTY - DEN
2 stops32h 06mMultiple Airlines
Deal found 11/19$590
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/164:51 pmDEN - PTY
2 stops18h 56mAmerican Airlines
Tue 12/234:55 pmPTY - DEN
2 stops20h 27mAmerican Airlines
Deal found 11/18$593
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/810:29 pmDEN - PTY
1 stop28h 51mMultiple Airlines
Mon 12/1511:25 amPTY - DEN
2 stops37h 39mMultiple Airlines
Deal found 11/20$605
This United Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/165:02 amDEN - PTY
1 stop7h 43mUnited Airlines
Tue 2/38:55 amPTY - DEN
1 stop9h 26mUnited Airlines
Deal found 11/19$608
This American Airlines deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/164:51 pmDEN - PTY
2 stops18h 56mAmerican Airlines
Tue 2/32:27 pmPTY - DEN
1 stop9h 43mAmerican Airlines
Deal found 11/19$612
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/1311:25 pmDEN - PTY
2 stops17h 30mMultiple Airlines
Wed 12/241:45 pmPTY - DEN
1 stop22h 18mMultiple Airlines
Deal found 11/20$616
This United Airlines deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/125:02 amDEN - PTY
1 stop10h 05mUnited Airlines
Tue 12/234:41 pmPTY - DEN
1 stop9h 03mUnited Airlines
Deal found 11/20$621
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:47 pmDEN - PTY
1 stop23h 00mAmerican Airlines
Thu 1/154:50 pmPTY - DEN
2 stops23h 24mAmerican Airlines
Deal found 11/18$626
This Kiwi.com deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:07 amDEN - PTY
2 stops35h 33mMultiple Airlines
Tue 12/23:39 pmPTY - DEN
1 stop19h 54mMultiple Airlines
Deal found 11/18$634

Cheapflights Fare Finder

 
Customize your flight search to find flights from Pueblo to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from Pueblo to Panama that are best for you.

Fly from

Pueblo

Fly to

Panama

Route

Depart

Return

Price

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sat 1/17

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Wed 1/28

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/13

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Sat 1/17

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/13

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Fri 1/23

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 1/13

9:38 pm-5:33 am

Nonstop5h 55m

Panama City Tocumen Intl

Thu 1/22

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 2/5

10:19 pm-6:10 am

Nonstop5h 51m

Panama City Tocumen Intl

Mon 2/9

12:56 pm-5:16 pm

Nonstop6h 20m

$548

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Wed 3/11

5:00 am-1:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Wed 3/18

3:41 pm-11:44 pm

1 stop9h 03m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Fri 2/27

7:45 am-7:38 pm

1 stop9h 53m

Panama City Tocumen Intl

Sun 3/8

3:41 pm-6:40 am

1 stop15h 59m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Sun 3/1

7:45 am-5:07 pm

1 stop7h 22m

Panama City Tocumen Intl

Mon 3/9

3:41 pm-11:44 pm

1 stop9h 03m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Thu 3/5

7:45 am-5:07 pm

1 stop7h 22m

Panama City Tocumen Intl

Tue 3/10

11:35 am-7:54 pm

1 stop9h 19m

$550

DenverPanama City

DEN - PTY

DENPTY

Denver Intl

Tue 3/17

5:00 am-1:45 pm

1 stop7h 45m

Panama City Tocumen Intl

Tue 3/24

11:35 am-11:44 pm

1 stop13h 09m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 24 results
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Best time to book a flight from Pueblo to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Pueblo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Pueblo to Panama
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 20, 2025.
Get a feel of what it's like to fly with Delta, Copa Airlines, and United Airlines from Pueblo to Panama by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,002 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,002 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,566 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,028 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,045 reviews
Delta
7.9
Good
8,002 reviews

Crew

8.5

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Pueblo to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Pueblo to Panama?

    There are many flights that can get you from Pueblo to Panama in 5h 55m. Fly via Copa Airlines to get the fastest option. The distance between Pueblo and Panama is about 2634 mi. Most flights are nonstop.

  • Can I find deals for flights from Pueblo to Panama that include hotel bookings?

    Yes. In addition to deals on Pueblo to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Pueblo to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Pueblo to Panama.

  • Can I find deals for business class flights from Pueblo to Panama?

    Yes. Cheapflights offers flight deals from Pueblo to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Pueblo to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Durango to Coxen Hole flights
Aspen to San José flights
Grand Junction to Managua flights
Durango to Managua flights
Montrose to San Salvador flights
Montrose to Philip S.W.Goldson flights
Gunnison to San Salvador flights
Vail to San Salvador flights
Denver to Tegucigalpa flights
Cortez to San José flights
Colorado Springs to Managua flights
Denver to San Pedro Town flights

Top airline flying from Pueblo to Panama

Discover the top airline that operate flights from Pueblo to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$556Average$651FlexibilityNo cancel feeOn-time69%

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