Panama

$205+ Cheap flights from Myrtle Beach (MYR) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/5. Fares are subject to change and may not be available on all flights or dates of travel.
MYR — PTY
Jan 26 — Feb 21
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Cheap flight deals from Myrtle Beach to Panama

Best flights from Myrtle Beach to Panama
Discover carefully curated flight deals from Myrtle Beach to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 27, 2025.

This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/55:44 pmMYR - PTY
2 stops21h 54mAmerican Airlines
Thu 3/54:05 pmPTY - MYR
2 stops16h 17mAmerican Airlines
Deal found 12/25$460
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:00 amMYR - PTY
1 stop7h 55mDelta
Thu 3/53:15 pmPTY - MYR
1 stop8h 42mDelta
Deal found 12/25$720
This Kiwi.com deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/29:54 amMYR - PTY
1 stop10h 25mMultiple Airlines
Fri 1/911:25 amPTY - MYR
2 stops31h 55mMultiple Airlines
Deal found 12/26$802
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:35 pmMYR - PTY
2 stops20h 47mAmerican Airlines
Thu 3/261:44 pmPTY - MYR
2 stops17h 47mAmerican Airlines
Deal found 12/25$510
This American Airlines deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/203:18 pmMYR - PTY
2 stops22h 32mAmerican Airlines
Mon 3/24:05 pmPTY - MYR
2 stops18h 39mAmerican Airlines
Deal found 12/25$520
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/196:00 amMYR - PTY
1 stop8h 03mDelta
Thu 3/262:28 pmPTY - MYR
1 stop8h 38mDelta
Deal found 12/25$868
This Delta deal was found by Cheapflights users on 12/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 amMYR - PTY
1 stop7h 50mDelta
Mon 3/23:15 pmPTY - MYR
1 stop8h 42mDelta
Deal found 12/25$893
This Delta deal was found by Cheapflights users on 12/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/26:00 amMYR - PTY
1 stop14h 00mDelta
Fri 1/93:20 pmPTY - MYR
1 stop8h 21mDelta
Deal found 12/26$981

Find flight deals from Myrtle Beach to Panama

Keep the following information in mind while searching for Myrtle Beach to Panama flight deals. Data was last updated December 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$460
(American Airlines)

One-way from

$205
(American Airlines)
Provider with most accurate pricing for Myrtle Beach Intl-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City Tocumen Intl flights.
From Myrtle Beach Intl to Panama
One-way flight from Myrtle Beach Intl to Panama

Cheapflights Fare Finder

 
Customize your flight search to find flights from Myrtle Beach to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
Use the filters below to find and compare flights from Myrtle Beach to Panama that are best for you.

Fly from

Myrtle Beach

Fly to

Panama

Route

Depart

Return

Price

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 2/5

5:44 pm-3:38 pm

2 stops21h 54m

Panama City Tocumen Intl

Thu 3/5

4:05 pm-8:22 am

2 stops16h 17m

$460

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:35 pm-2:22 pm

2 stops20h 47m

Panama City Tocumen Intl

Thu 3/26

1:44 pm-8:31 am

2 stops17h 47m

$510

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 2/20

3:18 pm-1:50 pm

2 stops22h 32m

Panama City Tocumen Intl

Mon 3/2

4:05 pm-10:44 am

2 stops18h 39m

$520

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 2/5

6:00 am-1:55 pm

1 stop7h 55m

Panama City Tocumen Intl

Thu 3/5

3:15 pm-11:57 pm

1 stop8h 42m

$720

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 1/2

9:54 am-8:19 pm

1 stop10h 25m

Panama City Tocumen Intl

Fri 1/9

11:25 am-7:20 pm

2 stops31h 55m

$802

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 3/19

6:00 am-1:03 pm

1 stop8h 03m

Panama City Tocumen Intl

Thu 3/26

2:28 pm-12:06 am

1 stop8h 38m

$868

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 2/20

6:00 am-1:50 pm

1 stop7h 50m

Panama City Tocumen Intl

Mon 3/2

3:15 pm-11:57 pm

1 stop8h 42m

$893

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Fri 1/2

6:00 am-8:00 pm

1 stop14h 00m

Panama City Tocumen Intl

Fri 1/9

3:20 pm-11:41 pm

1 stop8h 21m

$981

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 2/5

5:44 pm-3:38 pm

2 stops21h 54m

$205

Myrtle BeachPanama City

MYR - PTY

MYRPTY

Myrtle Beach Intl

Thu 2/5

6:00 am-1:55 pm

1 stop7h 55m

$327

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/25

Best time to book a flight from Myrtle Beach to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Myrtle Beach with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Myrtle Beach to Panama

What is the cheapest month to book a flight from Myrtle Beach to Panama?

Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Panama (average of $230). Flying from Myrtle Beach to Panama in April is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 27, 2025.
Read through reviews of airlines operating flights from Myrtle Beach to Panama, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Entertainment

6.9

Overall

7.2

Food

6.5

Crew

8.0

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Entertainment

6.9

Overall

7.2

Food

6.5

Crew

8.0

Boarding

7.5

Comfort

7.2

Reviews

1 / 20
10.0
Excellent

Jeremy,Dec 2025

OKC - CLT

Was an okay flight. Had extra seat empty beside me so was able to stretch a bit

Related info for your journey

Find useful and relevant information for your journey from Myrtle Beach to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • What airport do you fly from for flights from Myrtle Beach to Panama?

    Myrtle Beach Intl (MYR) is the airport you will fly out of if you book a flight from Myrtle Beach to Panama. It is only a 2.1 mi journey to Myrtle Beach Intl (MYR) from Myrtle Beach’s city center.

  • How long is the flight from Myrtle Beach to Panama?

    For as low as $460, American Airlines can have you in Panama from Myrtle Beach in 21h 54m. Myrtle Beach and Panama are separated by a distance of 1700 mi.

  • Can I find deals for flights from Myrtle Beach to Panama that include hotel bookings?

    Yes. In addition to deals on Myrtle Beach to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Myrtle Beach to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Myrtle Beach to Panama.

  • Can I find deals for business class flights from Myrtle Beach to Panama?

    Yes. Cheapflights offers flight deals from Myrtle Beach to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Myrtle Beach to Panama?

    Currently, July is the cheapest month in which you can book a flight from Myrtle Beach to Panama (average of $230). Flying from Myrtle Beach to Panama in April is currently the most expensive (average of $549). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Myrtle Beach to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top airline flying from Myrtle Beach to Panama

Discover the top airline that operate flights from Myrtle Beach to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$486Average$572FlexibilityNo cancel feeOn-time71%

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