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$443+ Cheap flights from Mobile (MOB) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — PTY
Dec 12 — Dec 191
Fri 12/12
Fri 12/19
1 adult, Economy
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Cheap flight deals from Mobile to Panama

Keep the following information in mind while searching for Mobile to Panama flight deals. Data was last updated November 12, 2025.

Round-trip from

$443
(Delta)
From Mobile to Panama
Search Deals

Find flight deals from Mobile to Panama

Cheapest flights from Mobile to Panama
Explore the most affordable flight options available from Mobile to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2025.

This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/1111:35 amMOB - PTY
1 stop26h 10mUnited Airlines
Sun 11/168:55 amPTY - MOB
1 stop8h 12mUnited Airlines
Deal found 11/11$725
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/203:03 pmMOB - PTY
2 stops23h 51mAmerican Airlines
Sun 1/44:55 pmPTY - MOB
2 stops18h 30mAmerican Airlines
Deal found 11/11$1,127
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/193:03 pmMOB - PTY
2 stops23h 51mAmerican Airlines
Sun 1/44:55 pmPTY - MOB
2 stops22h 37mAmerican Airlines
Deal found 11/11$1,431
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:40 amMOB - PTY
1 stop6h 58mUnited Airlines
Sun 1/44:41 pmPTY - MOB
1 stop20h 43mUnited Airlines
Deal found 11/12$1,696
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/204:50 pmMOB - PTY
1 stop25h 48mUnited Airlines
Sun 1/48:55 amPTY - MOB
1 stop28h 29mUnited Airlines
Deal found 11/12$1,790

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mobile to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 12, 2025.
Use the filters below to find and compare flights from Mobile to Panama that are best for you.

Fly from

Mobile

Fly to

Panama

Route

Depart

Return

Price

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Mon 5/11

12:10 pm-12:55 pm

1 stop24h 45m

Panama City Tocumen Intl

Thu 5/14

2:20 pm-10:55 pm

1 stop8h 35m

$443

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Mon 5/11

6:57 pm-12:15 pm

2 stops17h 18m

Panama City Tocumen Intl

Thu 5/14

1:55 pm-11:47 am

2 stops21h 52m

$550

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 12/20

3:03 pm-3:54 pm

2 stops23h 51m

Panama City Tocumen Intl

Sun 1/4

4:55 pm-10:25 am

2 stops18h 30m

$1,127

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Fri 12/19

3:03 pm-3:54 pm

2 stops23h 51m

Panama City Tocumen Intl

Sun 1/4

4:55 pm-2:32 pm

2 stops22h 37m

$1,431

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Fri 12/19

7:00 am-7:38 pm

1 stop11h 38m

Panama City Tocumen Intl

Sun 1/4

8:55 am-12:24 pm

1 stop28h 29m

$1,696

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 12/20

11:40 am-2:45 pm

1 stop26h 05m

Panama City Tocumen Intl

Sun 1/4

4:41 pm-4:09 pm

1 stop24h 28m

$1,790

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/10

Best time to book a flight from Mobile to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Mobile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to Panama

What is the cheapest month to book a flight from Mobile to Panama?

Currently, November is the cheapest month in which you can book a flight from Mobile to Panama (average of $231). Flying from Mobile to Panama in September is currently the most expensive (average of $550). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mobile to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Mobile to Panama?

    Mobile (MOB), located 11.8 mi from the city center, is the airport you fly out of when you book flights from Mobile to Panama.

  • How long is the flight from Mobile to Panama?

    For as low as $550, Delta can have you in Panama from Mobile in 17h 18m. Airlines will cover a distance of 1598 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Mobile to Panama that include hotel bookings?

    Yes. In addition to deals on Mobile to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mobile to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to Panama.

  • Can I find deals for business class flights from Mobile to Panama?

    Yes. Cheapflights offers flight deals from Mobile to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mobile to Panama?

    Currently, November is the cheapest month in which you can book a flight from Mobile to Panama (average of $231). Flying from Mobile to Panama in September is currently the most expensive (average of $550). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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