HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$508+ Cheap flights from Mobile (MOB) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/25. Fares are subject to change and may not be available on all flights or dates of travel.
MOB — PTY
Nov 15 — Nov 221
Sat 11/15
Sat 11/22
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Mobile to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Mobile to Panama

Keep the following information in mind while searching for Mobile to Panama flight deals. Data was last updated October 16, 2025.

Round-trip from

$508
(United Airlines)
From Mobile to Panama
Search Deals

Find flight deals from Mobile to Panama

Cheapest flights from Mobile to Panama
Explore the most affordable flight options available from Mobile to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/259:05 amMOB - PTY
1 stop9h 33mUnited Airlines
Wed 12/38:55 amPTY - MOB
1 stop8h 12mUnited Airlines
Deal found 10/15$508
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/297:00 amMOB - PTY
1 stop6h 45mUnited Airlines
Sat 12/611:35 amPTY - MOB
1 stop11h 12mUnited Airlines
Deal found 10/14$548
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/287:00 amMOB - PTY
1 stop11h 38mUnited Airlines
Tue 11/48:55 amPTY - MOB
1 stop27h 46mUnited Airlines
Deal found 10/15$657
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/196:59 pmMOB - PTY
2 stops19h 04mAmerican Airlines
Sat 10/253:15 pmPTY - MOB
2 stops23h 46mAmerican Airlines
Deal found 10/15$660
This United Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/199:20 amMOB - PTY
1 stop28h 54mUnited Airlines
Sat 10/253:30 pmPTY - MOB
1 stop20h 11mUnited Airlines
Deal found 10/15$686
This United Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:00 amMOB - PTY
1 stop11h 38mUnited Airlines
Sun 1/44:41 pmPTY - MOB
1 stop20h 43mUnited Airlines
Deal found 10/16$841
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:45 pmMOB - PTY
2 stops18h 08mAmerican Airlines
Sun 1/44:55 pmPTY - MOB
2 stops18h 30mAmerican Airlines
Deal found 10/14$1,027
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2510:27 amMOB - PTY
2 stops26h 26mAmerican Airlines
Fri 1/24:55 pmPTY - MOB
2 stops22h 12mAmerican Airlines
Deal found 10/14$1,068
This United Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:40 amMOB - PTY
1 stop6h 58mUnited Airlines
Fri 1/28:55 amPTY - MOB
1 stop13h 56mUnited Airlines
Deal found 10/14$1,216

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mobile to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 16, 2025.
Use the filters below to find and compare flights from Mobile to Panama that are best for you.

Fly from

Mobile

Fly to

Panama

Route

Depart

Return

Price

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Tue 11/25

9:05 am-7:38 pm

1 stop9h 33m

Panama City Tocumen Intl

Wed 12/3

8:55 am-4:07 pm

1 stop8h 12m

$508

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sun 11/30

7:00 am-7:38 pm

1 stop11h 38m

Panama City Tocumen Intl

Sun 12/7

8:55 am-4:07 pm

1 stop8h 12m

$548

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 11/29

7:00 am-2:45 pm

1 stop6h 45m

Panama City Tocumen Intl

Sat 12/6

11:35 am-9:47 pm

1 stop11h 12m

$548

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Tue 10/28

7:00 am-6:38 pm

1 stop11h 38m

Panama City Tocumen Intl

Tue 11/4

8:55 am-11:41 am

1 stop27h 46m

$657

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Fri 12/19

7:00 am-7:38 pm

1 stop11h 38m

Panama City Tocumen Intl

Sun 1/4

4:41 pm-12:24 pm

1 stop20h 43m

$841

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 12/20

6:45 pm-1:53 pm

2 stops18h 08m

Panama City Tocumen Intl

Sun 1/4

4:55 pm-10:25 am

2 stops18h 30m

$1,027

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Thu 12/25

10:27 am-1:53 pm

2 stops26h 26m

Panama City Tocumen Intl

Fri 1/2

4:55 pm-2:07 pm

2 stops22h 12m

$1,068

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Thu 12/25

11:40 am-7:38 pm

1 stop6h 58m

Panama City Tocumen Intl

Fri 1/2

8:55 am-9:51 pm

1 stop13h 56m

$1,216

MobilePanama City

MOB - PTY

MOBPTY

Mobile

Sat 12/20

4:50 pm-7:38 pm

1 stop25h 48m

Panama City Tocumen Intl

Sun 1/4

4:41 pm-12:24 pm

1 stop20h 43m

$1,482

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/15

Best time to book a flight from Mobile to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Mobile with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mobile to Panama

What is the cheapest month to book a flight from Mobile to Panama?

Currently, November is the cheapest month in which you can book a flight from Mobile to Panama (average of $231). Flying from Mobile to Panama in September is currently the most expensive (average of $550). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Mobile to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Mobile to Panama?

    Mobile (MOB), located 11.8 mi from the city center, is the airport you fly out of when you book flights from Mobile to Panama.

  • How long is the flight from Mobile to Panama?

    For as low as $508, United Airlines can have you in Panama from Mobile in 9h 33m. Airlines will cover a distance of 1598 mi.

  • Can I find deals for flights from Mobile to Panama that include hotel bookings?

    Yes. In addition to deals on Mobile to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mobile to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mobile to Panama.

  • Can I find deals for business class flights from Mobile to Panama?

    Yes. Cheapflights offers flight deals from Mobile to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mobile to Panama?

    Currently, November is the cheapest month in which you can book a flight from Mobile to Panama (average of $231). Flying from Mobile to Panama in September is currently the most expensive (average of $550). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Mobile to Panama

See prices for flight routes from nearby airports that may be better suited for you.
Atlanta to San José flights
Atlanta to Panama City flights
Atlanta to Liberia flights
Atlanta to San Salvador flights
Atlanta to Guatemala City flights
Atlanta to San Pedro Sula flights
Atlanta to Philip S.W.Goldson flights
Atlanta to Managua flights
Atlanta to Coxen Hole flights
Pensacola to Panama City flights
Birmingham to San José flights
Pensacola to San José flights
Birmingham to Coxen Hole flights
Pensacola to Managua flights
Birmingham to Guatemala City flights
Huntsville to San José flights
Birmingham to Philip S.W.Goldson flights
Pensacola to Philip S.W.Goldson flights
Birmingham to San Pedro Sula flights
Birmingham to Panama City flights
Birmingham to Liberia flights
Valparaiso to Panama City flights
Pensacola to Guatemala City flights
Pensacola to Liberia flights
Valparaiso to San José flights
Mobile to San José flights
Chattanooga to San José flights
Pensacola to Coxen Hole flights
Chattanooga to Philip S.W.Goldson flights
Huntsville to Liberia flights
Huntsville to Philip S.W.Goldson flights
Mobile to Panama City flights
Huntsville to Guatemala City flights
Valparaiso to Guatemala City flights
Valparaiso to Philip S.W.Goldson flights
Mobile to Coxen Hole flights
Mobile to Philip S.W.Goldson flights
Chattanooga to San Salvador flights
Mobile to San Pedro Sula flights
Pensacola to David flights
Atlanta to Tegucigalpa flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.