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$114+ Cheap flights from Michigan to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/18. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Michigan to Panama

Cheapest flights from Michigan to Panama
Explore the most affordable flight options available from Michigan to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Trip.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/1211:20 pm
ORD
-
PTY
1 stop17h 35m
Avianca
Sun 3/152:55 am
PTY
-
ORD
1 stop18h 25m
Avianca
Deal found 1/28$435
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/110:20 pm
ORD
-
PTY
1 stop14h 40m
Multiple Airlines
Sun 3/87:50 pm
PTY
-
ORD
3 stops22h 28m
Multiple Airlines
Deal found 1/27$436
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/137:10 am
ORD
-
PTY
2 stops17h 30m
Multiple Airlines
Fri 3/209:45 am
PTY
-
ORD
1 stop11h 35m
Multiple Airlines
Deal found 1/27$439
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:20 pm
ORD
-
PTY
1 stop9h 30m
Multiple Airlines
Sat 3/217:50 pm
PTY
-
ORD
2 stops36h 53m
Multiple Airlines
Deal found 1/27$440
This oojo deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure oojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:20 pm
ORD
-
PTY
1 stop25h 45m
Avianca
Wed 4/110:10 am
PTY
-
ORD
1 stop11h 10m
Avianca
Deal found 1/27$443
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/911:20 pm
ORD
-
PTY
1 stop9h 30m
Multiple Airlines
Mon 3/167:50 pm
PTY
-
ORD
3 stops21h 05m
Multiple Airlines
Deal found 1/27$445
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:20 pm
ORD
-
PTY
1 stop9h 30m
Multiple Airlines
Wed 3/259:34 am
PTY
-
ORD
2 stops13h 43m
Multiple Airlines
Deal found 1/28$452
This FlightHub deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/2811:20 pm
ORD
-
PTY
1 stop14h 55m
Avianca
Fri 4/33:10 pm
PTY
-
ORD
1 stop30h 10m
Avianca
Deal found 1/27$454
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2311:20 pm
ORD
-
PTY
1 stop14h 40m
Multiple Airlines
Thu 3/262:55 pm
PTY
-
ORD
2 stops17h 30m
Multiple Airlines
Deal found 1/27$455
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1611:20 pm
ORD
-
PTY
1 stop9h 30m
Avianca
Sat 3/219:45 am
PTY
-
ORD
1 stop11h 35m
Avianca
Deal found 1/27$459
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/510:20 pm
ORD
-
PTY
1 stop9h 30m
Avianca
Sat 3/73:55 am
PTY
-
ORD
1 stop17h 25m
Avianca
Deal found 1/27$460
This Mytrip deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/292:35 pm
ORD
-
PTY
1 stop19h 35m
Multiple Airlines
Thu 5/289:55 am
PTY
-
ORD
3 stops20h 51m
Multiple Airlines
Deal found 1/27$461

Find flight deals from Michigan to Panama

Keep the following information in mind while searching for Michigan to Panama flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$435
(Trip.com)

One-way from

$114
(Avianca)

Popular in

December

Cheapest in

January

Average price

$578
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
Search Deals
From Michigan to Panama
Search Deals
One-way flight from Michigan to Panama
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($93 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($36 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Michigan to Panama that are best for you.

Fly from

Michigan

Fly to

Panama

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 3/18

4:50 pm-8:50 am

2 stops17h 00m

Panama City Tocumen Intl

Wed 3/25

9:45 am-11:59 pm

2 stops13h 14m

$461

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/5

6:05 am-1:00 am

2 stops18h 55m

Panama City Tocumen Intl

Fri 3/13

2:55 am-7:22 pm

2 stops15h 27m

$465

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 3/11

8:49 am-12:40 am

2 stops16h 51m

Panama City Tocumen Intl

Mon 3/16

2:55 am-7:46 pm

2 stops15h 51m

$481

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 3/10

5:45 am-1:00 am

2 stops20h 15m

Panama City Tocumen Intl

Mon 3/16

2:55 am-7:46 pm

2 stops15h 51m

$481

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 3/4

5:45 am-12:40 am

2 stops18h 55m

Panama City Tocumen Intl

Wed 3/11

2:55 am-7:46 pm

2 stops15h 51m

$485

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 5/13

5:00 am-12:45 am

2 stops20h 45m

Panama City Tocumen Intl

Tue 5/19

3:20 am-9:34 pm

2 stops17h 14m

$502

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 3/19

12:22 pm-1:00 am

2 stops13h 38m

Panama City Tocumen Intl

Mon 3/23

9:45 am-11:59 pm

2 stops13h 14m

$514

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 4/30

8:06 am-1:22 pm

Nonstop5h 16m

Panama City Tocumen Intl

Sun 5/3

7:25 pm-1:15 am

Nonstop5h 50m

$557

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Thu 4/9

11:20 pm-2:15 pm

1 stop14h 55m

Panama City Tocumen Intl

Sat 4/11

3:05 am-9:20 pm

1 stop18h 15m

$564

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 4/5

8:06 am-1:22 pm

Nonstop5h 16m

Panama City Tocumen Intl

Fri 4/10

7:25 pm-1:13 am

Nonstop5h 48m

$565

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 58 results
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Best time to book a flight from Michigan to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to Panama

What is the cheapest month to book a flight from Michigan to Panama?

Currently, July is the cheapest month in which you can book a flight from Michigan to Panama (average of $241). Flying from Michigan to Panama in December is currently the most expensive (average of $596). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Michigan to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Michigan to Panama?

    For as low as $557, Copa Airlines can have you in Panama from Michigan in 5h 16m. There are 2330 mi between Michigan and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Michigan to Panama that include hotel bookings?

    Yes. In addition to deals on Michigan to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to Panama.

  • Can I find deals for business class flights from Michigan to Panama?

    Yes. Cheapflights offers flight deals from Michigan to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to Panama?

    Currently, July is the cheapest month in which you can book a flight from Michigan to Panama (average of $241). Flying from Michigan to Panama in December is currently the most expensive (average of $596). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Michigan to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Michigan to Panama

Discover the top 3 airlines that operate flights from Michigan to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$344Average$692FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$457Average$740FlexibilityNo cancel feeOn-time71%
DeltaCheapest$473Average$798FlexibilityNo cancel feeOn-timeN/A

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