HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$212+ Cheap flights from Michigan to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — PTY
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Michigan to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Michigan to Panama

Cheapest flights from Michigan to Panama
Explore the most affordable flight options available from Michigan to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Avianca Connect deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/295:23 pmDTW - PTY
2 stops20h 37mMultiple Airlines
Wed 1/212:55 amPTY - DTW
2 stops21h 04mMultiple Airlines
Deal found 12/17$684
This Copa Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/317:33 amORD - PTY
Nonstop5h 27mCopa Airlines
Wed 12/317:20 pmPTY - ORD
Nonstop5h 45mCopa Airlines
Deal found 12/17$724
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:54 amORD - PTY
1 stop9h 44mUnited Airlines
Tue 1/64:41 pmPTY - ORD
1 stop18h 26mUnited Airlines
Deal found 12/16$748
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/2410:35 amORD - PTY
1 stop8h 03mUnited Airlines
Wed 12/318:55 amPTY - ORD
1 stop10h 50mUnited Airlines
Deal found 12/16$757
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/219:23 pmORD - PTY
1 stop16h 22mUnited Airlines
Tue 12/308:55 amPTY - ORD
1 stop16h 19mUnited Airlines
Deal found 12/16$774
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/235:49 amORD - PTY
1 stop10h 18mUnited Airlines
Mon 12/2911:35 amPTY - ORD
1 stop12h 02mUnited Airlines
Deal found 12/16$775
This Copa Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/192:07 pmORD - PTY
Nonstop5h 28mCopa Airlines
Sat 12/277:20 pmPTY - ORD
Nonstop5h 45mCopa Airlines
Deal found 12/16$794
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:22 pmDTW - PTY
2 stops29h 38mMultiple Airlines
Sun 12/289:25 amPTY - DTW
1 stop8h 44mMultiple Airlines
Deal found 12/17$822
This Kiwi.com deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:20 amDTW - PTY
2 stops23h 52mMultiple Airlines
Thu 1/19:33 pmPTY - DTW
1 stop24h 43mMultiple Airlines
Deal found 12/15$836
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/179:08 pmORD - PTY
1 stop16h 37mUnited Airlines
Wed 12/248:55 amPTY - ORD
1 stop16h 19mUnited Airlines
Deal found 12/16$857
This United Airlines deal was found by Cheapflights users on 12/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:00 amDTW - PTY
1 stop8h 45mUnited Airlines
Thu 1/84:41 pmPTY - DTW
2 stops17h 29mUnited Airlines
Deal found 12/18$858
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:05 pmORD - PTY
2 stops20h 48mAmerican Airlines
Wed 12/312:53 pmPTY - ORD
1 stop9h 06mAmerican Airlines
Deal found 12/16$863

Find flight deals from Michigan to Panama

Keep the following information in mind while searching for Michigan to Panama flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$479
(Kiwi.com)

One-way from

$212
(Kiwi.com)

Popular in

December

Cheapest in

August

Average price

$1,354
Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.
Search Deals
From Michigan to Panama
Search Deals
One-way flight from Michigan to Panama
Search Deals
Highest demand for flights based on searches. 17% potential increase in price ($179 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 7% potential price decrease ($54 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Michigan to Panama that are best for you.

Fly from

Michigan

Fly to

Panama

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 2/19

10:16 am-1:00 am

2 stops14h 44m

Panama City Tocumen Intl

Tue 2/24

2:55 am-7:57 pm

2 stops17h 02m

$428

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Wed 1/14

9:23 am-7:20 pm

1 stop8h 57m

Panama City Tocumen Intl

Wed 1/21

2:55 pm-8:18 am

2 stops18h 23m

$519

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Wed 2/11

6:36 pm-2:00 pm

2 stops19h 24m

Panama City Tocumen Intl

Tue 2/24

2:55 am-7:57 pm

2 stops17h 02m

$527

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sun 1/18

9:23 am-7:20 pm

1 stop8h 57m

Panama City Tocumen Intl

Sun 1/25

5:50 pm-8:18 am

2 stops15h 28m

$535

KalamazooPanama City

AZO - PTY

AZOPTY

Kalamazoo Intl

Wed 2/18

2:57 pm-1:50 pm

2 stops22h 53m

Panama City Tocumen Intl

Wed 2/25

2:50 pm-11:57 am

2 stops21h 07m

$539

ChicagoPanama City

ORD - PTY

ORDPTY

Chicago O'Hare Intl

Sat 1/17

10:20 pm-4:55 pm

1 stop17h 35m

Panama City Tocumen Intl

Tue 1/20

9:45 am-8:20 pm

1 stop11h 35m

$541

LansingPanama City

LAN - PTY

LANPTY

Lansing Capital City

Thu 4/16

5:07 pm-12:15 pm

2 stops20h 08m

Panama City Tocumen Intl

Wed 4/22

1:55 pm-10:28 pm

2 stops31h 33m

$544

South BendPanama City

SBN - PTY

SBNPTY

South Bend/Michiana

Tue 4/14

9:35 am-7:31 pm

2 stops10h 56m

Panama City Tocumen Intl

Sat 4/18

7:55 am-11:01 pm

2 stops14h 06m

$546

FlintPanama City

FNT - PTY

FNTPTY

Flint Bishop

Thu 4/16

7:39 pm-2:14 pm

2 stops19h 35m

Panama City Tocumen Intl

Wed 4/22

10:55 pm-7:04 pm

2 stops19h 09m

$546

LansingPanama City

LAN - PTY

LANPTY

Lansing Capital City

Wed 2/18

5:23 pm-3:15 pm

2 stops21h 52m

Panama City Tocumen Intl

Sat 2/28

4:05 pm-1:50 pm

2 stops21h 45m

$546

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 54 results
1
2
3
...
6

Best time to book a flight from Michigan to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to Panama

What is the cheapest month to book a flight from Michigan to Panama?

Currently, July is the cheapest month in which you can book a flight from Michigan to Panama (average of $241). Flying from Michigan to Panama in December is currently the most expensive (average of $587). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MI to PA?

Find hourly flight availability from Michigan to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s optimal to fly from Michigan to Panama in the morning. By choosing this option you can save up to 34% on the cost of your flight, compared to a flight in the afternoon.

Related info for your journey

Find useful and relevant information for your journey from Michigan to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Michigan to Panama?

    For as low as $546, American Airlines can have you in Panama from Michigan in 10h 56m. There are 2292 mi between Michigan and Panama. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Michigan to Panama that include hotel bookings?

    Yes. In addition to deals on Michigan to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to Panama.

  • Can I find deals for business class flights from Michigan to Panama?

    Yes. Cheapflights offers flight deals from Michigan to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to Panama?

    Currently, July is the cheapest month in which you can book a flight from Michigan to Panama (average of $241). Flying from Michigan to Panama in December is currently the most expensive (average of $587). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Michigan to Panama

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to San José flights
John F Kennedy Intl to Panama City flights
Los Angeles to San Salvador flights
Dulles Intl to San Salvador flights
Newark to San José flights
Newark to Panama City flights
Los Angeles to Guatemala City flights
John F Kennedy Intl to Guatemala City flights
John F Kennedy Intl to Liberia flights
John F Kennedy Intl to San Salvador flights
Hobby to San Salvador flights
Los Angeles to San José flights
Dallas/Fort Worth to San Salvador flights
George Bush Intcntl to San Salvador flights
Dulles Intl to Panama City flights
Newark to Liberia flights
LaGuardia to San José flights
Dulles Intl to San José flights
Miami to Panama City flights
O'Hare Intl to San José flights
LaGuardia to Panama City flights
Newark to Guatemala City flights
Hobby to San José flights
Dallas/Fort Worth to San José flights
Boston to Liberia flights
Reagan-National to San Salvador flights
Baltimore to San Salvador flights
Los Angeles to Panama City flights
Boston to San José flights
Atlanta to San José flights
O'Hare Intl to Panama City flights
Reagan-National to San José flights
Miami to Managua flights
George Bush Intcntl to San José flights
Boston to Panama City flights
San Francisco to San José flights
Miami to San José flights
Denver to San José flights
Baltimore to San José flights
Atlanta to Panama City flights
LaGuardia to Liberia flights
Orlando to San José flights
Fort Lauderdale to San José flights
O'Hare Intl to Liberia flights
Los Angeles to Liberia flights
Dallas/Fort Worth to Panama City flights
LaGuardia to Guatemala City flights
Orlando to Panama City flights
Denver to Liberia flights
Dallas/Fort Worth to Guatemala City flights

Top 3 airlines flying from Michigan to Panama

Discover the top 3 airlines that operate flights from Michigan to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$443Average$692FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$446Average$716FlexibilityNo cancel feeOn-time71%
DeltaCheapest$473Average$777FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.