Panama

$212+ Cheap flights from Massachusetts to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/25. Fares are subject to change and may not be available on all flights or dates of travel.
BOS — PTY
May 10 — May 171
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Massachusetts to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Massachusetts to Panama

Cheapest flights from Massachusetts to Panama
Explore the most affordable flight options available from Massachusetts to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 10, 2026.

This Mytrip deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 pm
BOS
-
PTY
2 stops21h 15m
Multiple Airlines
Mon 4/275:55 pm
PTY
-
BOS
2 stops19h 06m
Multiple Airlines
Deal found 4/4$549
This Mytrip deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:00 pm
BOS
-
PTY
2 stops31h 35m
Multiple Airlines
Wed 4/294:25 am
PTY
-
BOS
3 stops26h 33m
Multiple Airlines
Deal found 4/4$553
This Mytrip deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:00 pm
BOS
-
PTY
2 stops31h 35m
Multiple Airlines
Tue 4/283:10 pm
PTY
-
BOS
2 stops31h 15m
Multiple Airlines
Deal found 4/4$572
This Super.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:45 am
BOS
-
PTY
1 stop16h 50m
Avianca
Fri 5/83:10 pm
PTY
-
BOS
1 stop14h 40m
Avianca
Deal found 4/5$590
This Mytrip deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:20 am
BOS
-
PTY
2 stops14h 15m
Multiple Airlines
Thu 5/144:25 am
PTY
-
BOS
2 stops18h 29m
Multiple Airlines
Deal found 4/6$591
This Super.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/14:50 pm
BOS
-
PTY
1 stop10h 05m
Avianca
Mon 5/45:55 pm
PTY
-
BOS
1 stop12h 15m
Avianca
Deal found 4/6$593
This Super.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/84:50 pm
BOS
-
PTY
1 stop10h 05m
Avianca
Sun 5/105:30 am
PTY
-
BOS
1 stop8h 20m
Avianca
Deal found 4/6$594
This Super.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/44:50 pm
BOS
-
PTY
1 stop10h 05m
Avianca
Mon 8/315:30 am
PTY
-
BOS
1 stop8h 20m
Avianca
Deal found 4/7$596
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:30 pm
ALB
-
PTY
2 stops20h 15m
United Airlines
Tue 11/104:41 pm
PTY
-
ALB
2 stops19h 16m
United Airlines
Deal found 4/5$627
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/74:55 pm
BDL
-
PTY
2 stops22h 19m
United Airlines
Tue 7/213:30 pm
PTY
-
BDL
2 stops17h 26m
United Airlines
Deal found 4/6$627
This KAYAK deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:30 pm
ALB
-
PTY
2 stops25h 32m
Copa Airlines
Tue 12/14:41 pm
PTY
-
ALB
2 stops24h 14m
Copa Airlines
Deal found 4/5$639
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
ALB
-
PTY
1 stop8h 02m
Delta
Tue 5/122:15 pm
PTY
-
ALB
1 stop8h 43m
Delta
Deal found 4/5$649

Find flight deals from Massachusetts to Panama

Keep the following information in mind while searching for Massachusetts to Panama flight deals. Data was last updated April 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$549
(Mytrip)

One-way from

$212
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$640

Good round-trip deal

$440 or less

Good one-way deal

$205 or less
Provider with most accurate pricing for Boston Logan Intl-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Boston Logan Intl-Panama City Tocumen Intl flights.
From Massachusetts to Panama
One-way flight from Massachusetts to Panama
Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Average for round-trip flights in April 2026
Price to beat on a round-trip flight from Massachusetts to Panama.
Price to beat on a one-way flight from Massachusetts to Panama.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Massachusetts to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
Use the filters below to find and compare flights from Massachusetts to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Sat 8/8

8:45 am-1:33 pm

Nonstop5h 48m

Panama City Tocumen Intl

Sat 8/15

4:18 pm-11:10 pm

Nonstop5h 52m

$610

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Sat 8/22

8:28 pm-4:04 am

1 stop8h 36m

Panama City Tocumen Intl

Sun 8/30

10:55 pm-8:11 am

1 stop8h 16m

$625

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Wed 7/8

8:26 pm-4:04 am

1 stop8h 38m

Panama City Tocumen Intl

Sat 7/18

9:45 am-7:28 pm

1 stop8h 43m

$625

HartfordPanama City

BDL - PTY

BDLPTY

Hartford Bradley Intl

Tue 7/7

4:55 pm-2:14 pm

2 stops22h 19m

Panama City Tocumen Intl

Tue 7/21

3:30 pm-9:56 am

2 stops17h 26m

$627

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Thu 7/2

5:59 pm-2:14 pm

2 stops21h 15m

Panama City Tocumen Intl

Mon 7/6

7:55 am-11:30 pm

1 stop14h 35m

$629

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Sat 8/15

7:00 pm-4:04 am

1 stop10h 04m

Panama City Tocumen Intl

Sat 8/22

10:55 pm-9:53 am

1 stop9h 58m

$645

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Sat 8/8

8:27 pm-4:04 am

1 stop8h 37m

Panama City Tocumen Intl

Tue 8/11

10:55 pm-8:11 am

1 stop8h 16m

$645

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Tue 5/5

6:00 am-1:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Tue 5/12

2:15 pm-11:58 pm

1 stop8h 43m

$649

BostonPanama City

BOS - PTY

BOSPTY

Boston Logan Intl

Mon 6/1

8:05 pm-4:12 pm

2 stops21h 07m

Panama City Tocumen Intl

Sat 6/6

3:30 pm-11:05 am

2 stops18h 35m

$649

AlbanyPanama City

ALB - PTY

ALBPTY

Albany Intl

Tue 5/5

6:00 am-6:37 pm

2 stops13h 37m

Panama City Tocumen Intl

Tue 5/12

7:55 am-9:12 pm

2 stops12h 17m

$653

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/8

Showing 1-10 of 49 resultsSorted by cheapest first
1
2
3
...
5

Best time to book a flight from Massachusetts to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Massachusetts with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Massachusetts to Panama

What is the cheapest month to book a flight from Massachusetts to Panama?

Currently, June is the cheapest month in which you can book a flight from Massachusetts to Panama (average of $280). Flying from Massachusetts to Panama in December is currently the most expensive (average of $570). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MA to PA?

Find hourly flight availability from Massachusetts to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 10, 2026.

When flying from Massachusetts to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Massachusetts to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Massachusetts to Panama flight route?

  • How long is the flight from Massachusetts to Panama?

    Airlines like Copa Airlines, United Airlines, and Delta fly from Massachusetts to Panama in about 5h 48m. The time it takes to get you to your destination can typically vary by up to 2h 48m. There are 2354 mi between Massachusetts and Panama. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Massachusetts to Panama that include hotel bookings?

    Yes. In addition to deals on Massachusetts to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Massachusetts to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Massachusetts to Panama.

  • Can I find deals for business class flights from Massachusetts to Panama?

    Yes. Cheapflights offers flight deals from Massachusetts to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Massachusetts to Panama?

    Currently, June is the cheapest month in which you can book a flight from Massachusetts to Panama (average of $280). Flying from Massachusetts to Panama in December is currently the most expensive (average of $570). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Massachusetts to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Massachusetts to Panama

Discover the top 5 airlines that operate flights from Massachusetts to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$187Average$559FlexibilityNo cancel feeOn-timeN/A
AviancaCheapest$322Average$501FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$472Average$737FlexibilityNo cancel feeOn-time70%
American AirlinesCheapest$547Average$766FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$559Average$763FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.