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$248+ Cheap flights from Lexington (LEX) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/11. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — PTY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Lexington to Panama

Keep the following information in mind while searching for Lexington to Panama flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$604
(United Airlines)

One-way from

$248
(American Airlines)

Popular in

August

Cheapest in

February
Provider with most accurate pricing for Lexington Blue Grass-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Lexington Blue Grass-Panama City Tocumen Intl flights.
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From Lexington Blue Grass to Panama
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One-way flight from Lexington Blue Grass to Panama
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Highest demand for flights based on searches. 36% potential increase in price ($524 potential increase over avg. RT price).
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Cheapest flight prices on average. 27% potential price decrease ($198 potential savings vs. average RT price).
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Find flight deals from Lexington to Panama

Cheapest flights from Lexington to Panama
Explore the most affordable flight options available from Lexington to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:59 pmLEX - PTY
2 stops24h 46mUnited Airlines
Mon 1/124:41 pmPTY - LEX
2 stops20h 44mUnited Airlines
Deal found 10/29$604
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:47 pmLEX - PTY
2 stops20h 58mUnited Airlines
Sat 12/204:41 pmPTY - LEX
2 stops20h 35mUnited Airlines
Deal found 10/29$606
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:59 pmLEX - PTY
2 stops24h 46mUnited Airlines
Fri 12/511:55 pmPTY - LEX
2 stops13h 27mUnited Airlines
Deal found 10/29$624
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:03 pmLEX - PTY
2 stops21h 51mAmerican Airlines
Mon 1/54:55 pmPTY - LEX
2 stops24h 04mAmerican Airlines
Deal found 10/30$896
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/281:59 pmLEX - PTY
2 stops24h 46mUnited Airlines
Mon 1/54:41 pmPTY - LEX
2 stops20h 44mUnited Airlines
Deal found 10/29$1,082
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/266:00 amLEX - PTY
1 stop14h 35mUnited Airlines
Mon 1/57:40 pmPTY - LEX
1 stop17h 45mUnited Airlines
Deal found 10/30$5,255

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Lexington to Panama that are best for you.

Fly from

Lexington

Fly to

Panama

Route

Depart

Return

Price

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 11/28

1:59 pm-2:45 pm

2 stops24h 46m

Panama City Tocumen Intl

Mon 1/12

4:41 pm-1:25 pm

2 stops20h 44m

$604

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 11/28

1:59 pm-2:45 pm

2 stops24h 46m

Panama City Tocumen Intl

Fri 12/5

11:55 pm-1:22 pm

2 stops13h 27m

$624

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 4/4

5:50 pm-4:12 pm

2 stops23h 22m

Panama City Tocumen Intl

Sun 4/12

3:20 pm-4:55 pm

2 stops24h 35m

$637

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 4/4

6:31 am-2:20 pm

1 stop8h 49m

Panama City Tocumen Intl

Sun 4/12

1:55 pm-10:32 am

2 stops19h 37m

$792

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 12/26

6:03 pm-3:54 pm

2 stops21h 51m

Panama City Tocumen Intl

Mon 1/5

4:55 pm-4:59 pm

2 stops24h 04m

$896

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 11/28

1:59 pm-2:45 pm

2 stops24h 46m

Panama City Tocumen Intl

Mon 1/5

4:41 pm-1:25 pm

2 stops20h 44m

$1,082

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 4/4

7:10 am-12:55 pm

1 stop6h 45m

Panama City Tocumen Intl

Sun 4/12

2:20 pm-11:55 pm

1 stop8h 35m

$1,587

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Thu 12/11

8:09 pm-3:42 pm

2 stops19h 33m

$248

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 11/29

7:12 pm-1:43 pm

2 stops18h 31m

$274

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Thu 12/11

11:18 am-12:40 am

3 stops37h 22m

$312

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 11 results
1
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Best time to book a flight from Lexington to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Panama

What is the cheapest month to book a flight from Lexington to Panama?

Currently, June is the cheapest month in which you can book a flight from Lexington to Panama (average of $337). Flying from Lexington to Panama in November is currently the most expensive (average of $455). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from LEX to PA?

Find hourly flight availability from Lexington to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

When flying from Lexington to Panama, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 62% versus a flight at noon.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Delta from Lexington to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Overall

7.9

Boarding

8.2

Entertainment

7.9

Crew

8.5

Comfort

7.9

Food

7.3

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lexington to Panama?

    Lexington Blue Grass (LEX) is the airport you will fly out of if you book a flight from Lexington to Panama. It is only a 5.6 mi journey to Blue Grass (LEX) from Lexington’s city center.

  • How long is the flight from Lexington to Panama?

    Airlines like United Airlines fly from Lexington to Panama in about 24h 46m. The time it takes to get you to your destination can typically vary by up to . Lexington and Panama are separated by a distance of 2026 mi.

  • Can I find deals for flights from Lexington to Panama that include hotel bookings?

    Yes. In addition to deals on Lexington to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Panama.

  • Can I find deals for business class flights from Lexington to Panama?

    Yes. Cheapflights offers flight deals from Lexington to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Panama?

    Currently, June is the cheapest month in which you can book a flight from Lexington to Panama (average of $337). Flying from Lexington to Panama in November is currently the most expensive (average of $455). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Lexington to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Lexington to Panama

Discover the top airline that operate flights from Lexington to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$665Average$757FlexibilityNo cancel feeOn-timeN/A

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