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$607+ Cheap flights from Lexington (LEX) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
LEX — PTY
Mar 6 — Mar 131
Fri 3/6
Fri 3/13
1 adult, Economy
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Cheap flight deals from Lexington to Panama

Cheapest flights from Lexington to Panama
Explore the most affordable flight options available from Lexington to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 4, 2026.

This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:07 pm
LEX
-
PTY
2 stops20h 33m
American Airlines
Mon 3/163:10 pm
PTY
-
LEX
2 stops21h 13m
American Airlines
Deal found 2/2$607
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/47:00 am
LEX
-
PTY
2 stops12h 38m
United Airlines
Mon 3/163:41 pm
PTY
-
LEX
2 stops20h 34m
United Airlines
Deal found 2/2$614
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/15:45 pm
LEX
-
PTY
2 stops23h 22m
United Airlines
Wed 3/44:41 pm
PTY
-
LEX
2 stops24h 14m
United Airlines
Deal found 2/3$627
This Gurufare deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:14 pm
LEX
-
PTY
2 stops21h 00m
Copa Airlines
Thu 7/210:55 pm
PTY
-
LEX
2 stops18h 42m
Copa Airlines
Deal found 2/2$708
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/105:32 pm
LEX
-
PTY
2 stops23h 35m
United Airlines
Sun 2/154:41 pm
PTY
-
LEX
2 stops20h 34m
United Airlines
Deal found 2/2$712
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/65:50 pm
LEX
-
PTY
2 stops19h 56m
American Airlines
Sun 4/121:49 pm
PTY
-
LEX
2 stops22h 46m
American Airlines
Deal found 2/2$742
This United Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/45:45 pm
LEX
-
PTY
2 stops21h 29m
United Airlines
Sat 4/113:30 pm
PTY
-
LEX
2 stops20h 43m
United Airlines
Deal found 2/2$743
This American Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/44:59 pm
LEX
-
PTY
2 stops20h 41m
American Airlines
Sun 4/121:49 pm
PTY
-
LEX
2 stops22h 46m
American Airlines
Deal found 2/3$762
This United Airlines deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/275:45 pm
LEX
-
PTY
2 stops23h 22m
United Airlines
Mon 3/24:41 pm
PTY
-
LEX
2 stops20h 34m
United Airlines
Deal found 2/3$763
This American Airlines deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/135:07 pm
LEX
-
PTY
2 stops22h 08m
American Airlines
Mon 2/164:05 pm
PTY
-
LEX
2 stops21h 13m
American Airlines
Deal found 2/2$789
This Faresmojo deal was found by Cheapflights users on 2/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/46:00 am
LEX
-
PTY
1 stop7h 50m
JetBlue
Mon 3/162:28 pm
PTY
-
LEX
1 stop17h 52m
JetBlue
Deal found 2/2$804
This Delta deal was found by Cheapflights users on 2/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
LEX
-
PTY
1 stop7h 50m
Delta
Mon 3/23:15 pm
PTY
-
LEX
1 stop8h 33m
Delta
Deal found 2/3$859

Find flight deals from Lexington to Panama

Keep the following information in mind while searching for Lexington to Panama flight deals. Data was last updated February 4, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$607
(American Airlines)

One-way from

$319
(United Airlines)

Popular in

August

Cheapest in

March

Average price

$1,571
Provider with most accurate pricing for Lexington Blue Grass-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lexington Blue Grass-Panama City Tocumen Intl flights.
Search Deals
From Lexington Blue Grass to Panama
Search Deals
One-way flight from Lexington Blue Grass to Panama
Search Deals
Highest demand for flights based on searches. 29% potential increase in price ($422 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 22% potential price decrease ($186 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Lexington to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
Use the filters below to find and compare flights from Lexington to Panama that are best for you.

Fly from

Lexington

Fly to

Panama

Route

Depart

Return

Price

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Wed 3/11

5:07 pm-12:40 pm

2 stops20h 33m

Panama City Tocumen Intl

Mon 3/16

3:10 pm-1:23 pm

2 stops21h 13m

$607

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Wed 3/4

7:00 am-7:38 pm

2 stops12h 38m

Panama City Tocumen Intl

Mon 3/16

3:41 pm-1:15 pm

2 stops20h 34m

$614

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sun 3/1

5:45 pm-2:45 pm

2 stops21h 00m

Panama City Tocumen Intl

Wed 3/4

11:35 am-11:49 pm

2 stops12h 14m

$627

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 6/27

6:14 pm-2:14 pm

2 stops21h 00m

Panama City Tocumen Intl

Thu 7/2

10:55 pm-6:37 pm

2 stops18h 42m

$708

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Mon 4/6

5:50 pm-12:46 pm

2 stops19h 56m

Panama City Tocumen Intl

Sun 4/12

1:49 pm-1:35 pm

2 stops22h 46m

$742

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 4/4

5:45 pm-2:14 pm

2 stops21h 29m

Panama City Tocumen Intl

Sat 4/11

3:30 pm-1:13 pm

2 stops20h 43m

$743

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Sat 4/4

7:10 pm-3:01 pm

2 stops20h 51m

Panama City Tocumen Intl

Sun 4/12

1:49 pm-1:35 pm

2 stops22h 46m

$762

LexingtonPanama City

LEX - PTY

LEXPTY

Lexington Blue Grass

Fri 2/27

5:45 pm-5:07 pm

2 stops23h 22m

Panama City Tocumen Intl

Mon 3/2

4:41 pm-1:15 pm

2 stops20h 34m

$763

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/2

Best time to book a flight from Lexington to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Lexington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Lexington to Panama

What is the cheapest month to book a flight from Lexington to Panama?

Currently, May is the cheapest month in which you can book a flight from Lexington to Panama (average of $237). Flying from Lexington to Panama in November is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated February 4, 2026.
Peruse reviews from past customers who have flown with Delta from Lexington to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,138 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,138 reviews
Delta
7.9
Good
8,138 reviews

Overall

7.9

Comfort

7.9

Boarding

8.1

Food

7.2

Crew

8.5

Entertainment

7.8

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Lexington to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Lexington to Panama?

    Lexington Blue Grass (LEX) is the airport you will fly out of if you book a flight from Lexington to Panama. It is only a 5.6 mi journey to Blue Grass (LEX) from Lexington’s city center.

  • How long is the flight from Lexington to Panama?

    Airlines like American Airlines and United Airlines fly from Lexington to Panama in about 12h 38m. The time it takes to get you to your destination can typically vary by up to 8h 47m. Lexington and Panama are separated by a distance of 2026 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Lexington to Panama that include hotel bookings?

    Yes. In addition to deals on Lexington to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Lexington to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Lexington to Panama.

  • Can I find deals for business class flights from Lexington to Panama?

    Yes. Cheapflights offers flight deals from Lexington to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Lexington to Panama?

    Currently, May is the cheapest month in which you can book a flight from Lexington to Panama (average of $237). Flying from Lexington to Panama in November is currently the most expensive (average of $478). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Lexington to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Lexington to Panama

Discover the top airline that operate flights from Lexington to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 4, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$665Average$757FlexibilityNo cancel feeOn-timeN/A

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