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$522+ Cheap flights from Harrisburg (MDT) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/12. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
Jul 5 — Jul 121
Sat 7/5
Sat 7/12
1 adult, Economy
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Cheap flight deals from Harrisburg to Panama

Keep the following information in mind while searching for Harrisburg to Panama flight deals. Data was last updated June 30, 2025.

Round-trip from

$522
(Delta)

Popular in

February

Cheapest in

August

Average price

$699
From Harrisburg to Panama
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($11 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Harrisburg to Panama

Cheapest flights from Harrisburg to Panama
Explore the most affordable flight options available from Harrisburg to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 30, 2025.

This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/125:00 pmMDT - PTY
2 stops20h 47mDelta
Thu 10/162:12 pmPTY - MDT
2 stops20h 45mDelta
Deal found 6/29$522
This American Airlines deal was found by Cheapflights users on 6/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:27 pmMDT - PTY
2 stops20h 58mAmerican Airlines
Mon 12/82:45 pmPTY - MDT
2 stops18h 15mAmerican Airlines
Deal found 6/27$564
This United Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/126:30 amMDT - PTY
2 stops13h 07mUnited Airlines
Tue 8/1910:00 amPTY - MDT
2 stops26h 48mUnited Airlines
Deal found 6/28$629

Cheapflights Fare Finder

Customize your flight search to find flights from Harrisburg to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
Use the filters below to find and compare flights from Harrisburg to Panama that are best for you.

Fly from

Harrisburg

Fly to

Panama

Route

Depart

Return

Price

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Sun 10/12

5:00 pm-12:47 pm

2 stops20h 47m

Panama City Tocumen Intl

Thu 10/16

2:12 pm-11:57 am

2 stops20h 45m

$522

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 12/4

6:27 pm-3:25 pm

2 stops20h 58m

Panama City Tocumen Intl

Mon 12/8

2:45 pm-9:00 am

2 stops18h 15m

$564

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 8/12

6:30 am-6:37 pm

2 stops13h 07m

Panama City Tocumen Intl

Tue 8/19

10:00 am-1:48 pm

2 stops26h 48m

$629

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/29

Best time to book a flight from Harrisburg to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama

What is the cheapest month to book a flight from Harrisburg to Panama?

Currently, October is the cheapest month in which you can book a flight from Harrisburg to Panama (average of $478). Flying from Harrisburg to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDT to PA?

Find hourly flight availability from Harrisburg to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Harrisburg to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 30, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Harrisburg to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,973 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,973 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,852 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,973 reviews

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Panama?

    Harrisburg (MDT), located 8.5 mi from the city center, is the airport you fly out of when you book flights from Harrisburg to Panama.

  • Can I find deals for flights from Harrisburg to Panama that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama.

  • Can I find deals for business class flights from Harrisburg to Panama?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama?

    Currently, October is the cheapest month in which you can book a flight from Harrisburg to Panama (average of $478). Flying from Harrisburg to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Harrisburg to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from Harrisburg to Panama

Discover the top 2 airlines that operate flights from Harrisburg to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$501Average$546FlexibilityNo cancel feeOn-time71%
DeltaCheapest$531Average$744FlexibilityNo cancel feeOn-timeN/A

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