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Panama

$627+ Cheap flights from Harrisburg (MDT) to Panama

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/15. Fares are subject to change and may not be available on all flights or dates of travel.
MDT — PTY
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Cheap flight deals from Harrisburg to Panama

Cheapest flights from Harrisburg to Panama
Explore the most affordable flight options available from Harrisburg to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/156:15 am
MDT
-
PTY
2 stops14h 16m
United Airlines
Tue 6/3010:55 pm
PTY
-
MDT
2 stops16h 59m
United Airlines
Deal found 3/26$627
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/66:30 am
MDT
-
PTY
2 stops13h 07m
United Airlines
Wed 5/139:45 am
PTY
-
MDT
2 stops12h 43m
United Airlines
Deal found 3/22$630
This United Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:15 am
MDT
-
PTY
2 stops10h 57m
United Airlines
Sun 5/310:55 pm
PTY
-
MDT
2 stops16h 58m
United Airlines
Deal found 3/22$633
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/215:53 pm
MDT
-
PTY
2 stops21h 21m
United Airlines
Fri 9/253:20 pm
PTY
-
MDT
2 stops21h 17m
United Airlines
Deal found 3/26$640
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:00 pm
MDT
-
PTY
2 stops21h 12m
United Airlines
Mon 4/133:30 pm
PTY
-
MDT
2 stops17h 39m
United Airlines
Deal found 3/26$653
This Kiwi.com deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:16 pm
MDT
-
PTY
2 stops31h 19m
Multiple Airlines
Thu 4/3012:03 pm
PTY
-
MDT
1 stop28h 23m
Multiple Airlines
Deal found 3/24$669
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:40 pm
MDT
-
PTY
2 stops25h 58m
United Airlines
Sun 3/297:55 am
PTY
-
MDT
2 stops24h 49m
United Airlines
Deal found 3/24$673
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
MDT
-
PTY
1 stop8h 02m
Delta
Wed 4/292:27 pm
PTY
-
MDT
1 stop8h 32m
Delta
Deal found 3/24$676
This United Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:59 pm
MDT
-
PTY
2 stops19h 15m
United Airlines
Mon 7/203:30 pm
PTY
-
MDT
2 stops17h 14m
United Airlines
Deal found 3/25$686
This United Airlines deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/276:15 am
MDT
-
PTY
2 stops13h 47m
United Airlines
Sun 3/297:55 am
PTY
-
MDT
2 stops24h 49m
United Airlines
Deal found 3/24$699
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/206:00 am
MDT
-
PTY
1 stop8h 02m
Delta
Thu 4/302:27 pm
PTY
-
MDT
1 stop8h 32m
Delta
Deal found 3/24$703
This Ovago deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/204:19 pm
MDT
-
PTY
2 stops21h 43m
LATAM Airlines
Wed 4/292:27 pm
PTY
-
MDT
1 stop8h 32m
LATAM Airlines
Deal found 3/24$723

Find flight deals from Harrisburg to Panama

Keep the following information in mind while searching for Harrisburg to Panama flight deals. Data was last updated March 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$627
(United Airlines)
Provider with most accurate pricing for Harrisburg-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Harrisburg-Panama City Tocumen Intl flights.
Search Deals
From Harrisburg to Panama
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Harrisburg to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Harrisburg to Panama that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Wed 5/6

6:30 am-6:37 pm

2 stops13h 07m

Panama City Tocumen Intl

Wed 5/13

9:45 am-11:28 pm

2 stops12h 43m

$630

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Tue 4/28

6:15 am-4:12 pm

2 stops10h 57m

Panama City Tocumen Intl

Sun 5/3

10:55 pm-4:53 pm

2 stops16h 58m

$633

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Mon 9/21

7:59 pm-6:37 pm

2 stops23h 38m

Panama City Tocumen Intl

Fri 9/25

9:45 am-9:24 am

2 stops22h 39m

$640

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Mon 5/11

5:49 pm-2:14 pm

2 stops21h 25m

Panama City Tocumen Intl

Mon 5/18

3:30 pm-1:55 pm

2 stops21h 25m

$640

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Mon 4/20

8:00 pm-2:14 pm

2 stops19h 14m

Panama City Tocumen Intl

Thu 4/30

3:30 pm-10:07 am

2 stops17h 37m

$653

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 5/8

2:40 pm-2:14 pm

2 stops24h 34m

Panama City Tocumen Intl

Fri 5/15

7:55 am-12:55 am

2 stops16h 00m

$653

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 4/10

6:15 am-6:37 pm

2 stops13h 22m

Panama City Tocumen Intl

Tue 4/14

10:00 am-10:09 am

2 stops23h 09m

$653

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Fri 4/10

8:00 pm-4:12 pm

2 stops21h 12m

Panama City Tocumen Intl

Mon 4/13

3:30 pm-10:09 am

2 stops17h 39m

$653

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Mon 4/20

6:15 am-7:31 pm

2 stops14h 16m

Panama City Tocumen Intl

Wed 4/29

10:00 am-11:28 pm

2 stops12h 28m

$653

HarrisburgPanama City

MDT - PTY

MDTPTY

Harrisburg

Thu 7/16

7:59 pm-2:14 pm

2 stops19h 15m

Panama City Tocumen Intl

Mon 7/20

3:30 pm-9:44 am

2 stops17h 14m

$686

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/22

Sorted by cheapest first

Best time to book a flight from Harrisburg to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Harrisburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Harrisburg to Panama

What is the cheapest month to book a flight from Harrisburg to Panama?

Currently, December is the cheapest month in which you can book a flight from Harrisburg to Panama (average of $340). Flying from Harrisburg to Panama in January is currently the most expensive (average of $477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated March 27, 2026.
Peruse reviews from past customers who have flown with Delta from Harrisburg to Panama to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,340 reviews

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,340 reviews
Delta
7.9
Good
8,340 reviews

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Harrisburg to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Harrisburg to Panama?

    Harrisburg (MDT), located 8.5 mi from the city center, is the airport you fly out of when you book flights from Harrisburg to Panama.

  • How long is the flight from Harrisburg to Panama?

    Departing from Harrisburg to Panama will take you 13h 07m. There are 2155 mi between Harrisburg and Panama.

  • Can I find deals for flights from Harrisburg to Panama that include hotel bookings?

    Yes. In addition to deals on Harrisburg to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Harrisburg to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Harrisburg to Panama.

  • Can I find deals for business class flights from Harrisburg to Panama?

    Yes. Cheapflights offers flight deals from Harrisburg to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Harrisburg to Panama?

    Currently, December is the cheapest month in which you can book a flight from Harrisburg to Panama (average of $340). Flying from Harrisburg to Panama in January is currently the most expensive (average of $477). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Harrisburg to Panama

See prices for flight routes from nearby airports that may be better suited for you.
John F Kennedy Intl to Panama City flights
John F Kennedy Intl to San José flights
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LaGuardia to Guatemala City flights
John F Kennedy Intl to San Pedro Sula flights
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Newark to Philip S.W.Goldson flights
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LaGuardia to San Pedro Sula flights
Reagan-National to Guatemala City flights
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Dulles Intl to San Pedro Sula flights
Philadelphia to Liberia flights
Philadelphia to Panama City flights
Newark to Managua flights
Philadelphia to Guatemala City flights
Philadelphia to Philip S.W.Goldson flights
Reagan-National to Managua flights
Reagan-National to San Pedro Sula flights
LaGuardia to Coxen Hole flights
Pittsburgh to San José flights
Philadelphia to San Salvador flights

Top airline flying from Harrisburg to Panama

Discover the top airline that operate flights from Harrisburg to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$216Average$628FlexibilityNo cancel feeOn-timeN/A

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