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$176+ Cheap flights from Durham, NC to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
Aug 5 — Aug 121
Tue 8/5
Tue 8/12
1 adult, Economy
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Cheap flight deals from Durham to Panama

Keep the following information in mind while searching for Durham to Panama flight deals. Data was last updated July 31, 2025.

Round-trip from

$353
(Copa Airlines)

One-way from

$176
(Kiwi.com)

Popular in

December

Cheapest in

November

Average price

$491
From Durham to Panama
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One-way flight from Durham to Panama
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Highest demand for flights based on searches. 1% potential increase in price ($8 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Durham to Panama

Cheapest flights from Durham to Panama
Explore the most affordable flight options available from Durham to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 31, 2025.

This Copa Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/254:22 pmRDU - PTY
Nonstop4h 24mCopa Airlines
Sun 9/78:57 amPTY - RDU
Nonstop4h 30mCopa Airlines
Deal found 7/30$353
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:15 amRDU - PTY
1 stop8h 41mDelta
Wed 10/222:21 pmPTY - RDU
1 stop8h 41mDelta
Deal found 7/30$367
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:00 amRDU - PTY
1 stop9h 31mAmerican Airlines
Sun 9/283:31 pmPTY - RDU
1 stop7h 14mAmerican Airlines
Deal found 7/30$372
This United Airlines deal was found by Cheapflights users on 7/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/266:00 amRDU - PTY
1 stop13h 37mUnited Airlines
Wed 10/13:30 pmPTY - RDU
1 stop19h 01mUnited Airlines
Deal found 7/31$530
This Kiwi.com deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/169:23 amRDU - PTY
2 stops12h 47mMultiple Airlines
Thu 10/239:33 pmPTY - RDU
1 stop16h 28mMultiple Airlines
Deal found 7/30$575

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
Use the filters below to find and compare flights from Durham to Panama that are best for you.

Fly from

Durham

Fly to

Panama

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 8/25

4:22 pm-7:46 pm

Nonstop4h 24m

Panama City Tocumen Intl

Sun 9/7

8:57 am-2:27 pm

Nonstop4h 30m

$353

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Tue 10/14

5:15 am-12:56 pm

1 stop8h 41m

Panama City Tocumen Intl

Wed 10/22

2:21 pm-12:02 am

1 stop8h 41m

$367

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 9/19

6:00 am-2:31 pm

1 stop9h 31m

Panama City Tocumen Intl

Sun 9/28

3:31 pm-11:45 pm

1 stop7h 14m

$372

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 9/26

6:00 am-6:37 pm

1 stop13h 37m

Panama City Tocumen Intl

Wed 10/1

3:30 pm-11:31 am

1 stop19h 01m

$530

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Thu 10/16

9:23 am-9:10 pm

2 stops12h 47m

Panama City Tocumen Intl

Thu 10/23

9:33 pm-3:01 pm

1 stop16h 28m

$575

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 8/18

7:56 pm-9:10 pm

2 stops26h 14m

$176

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 8/18

7:53 pm-2:30 pm

1 stop19h 37m

$263

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 8/18

4:22 pm-7:46 pm

Nonstop4h 24m

$419

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 10/13

6:18 am-12:56 pm

1 stop7h 38m

$545

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sat 10/11

6:00 am-9:10 pm

2 stops40h 10m

$559

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/31

Showing 1-10 of 11 results
1
2

Best time to book a flight from Durham to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Panama

What is the cheapest month to book a flight from Durham to Panama?

Currently, October is the cheapest month in which you can book a flight from Durham to Panama (average of $478). Flying from Durham to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to PA?

Find hourly flight availability from Durham to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 31, 2025.

When flying from Durham to Panama, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated July 31, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from Durham to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,981 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,900 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Avianca
6.7
Okay
2,388 reviews
Delta
8.0
Very good
7,981 reviews

Comfort

7.9

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Durham to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Durham to Panama flight route?

    The Durham to Panama flight path was viewed by 36 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines to fly from Durham to Panama one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $253. However, be on the lookout for offers from Copa Airlines and Delta, as they are both options that can get you from Durham to Panama for a low price.

  • What are the cheapest flights from Durham to Panama?

    On average you can expect to pay $744 for a flight from Durham to Panama. The cheapest flight overall is $163 while the most popular route, (Raleigh-Durham - Panama City Tocumen Intl) is currently priced at $353.

  • Can I find deals for flights from Durham to Panama that include hotel bookings?

    Yes. In addition to deals on Durham to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Panama.

  • Can I find deals for business class flights from Durham to Panama?

    Yes. Cheapflights offers flight deals from Durham to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Panama?

    Currently, October is the cheapest month in which you can book a flight from Durham to Panama (average of $478). Flying from Durham to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Greensboro to Guatemala City flights
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Knoxville to Philip S.W.Goldson flights
Knoxville to Liberia flights
Asheville to Guatemala City flights
Wilmington to Panama City flights
Knoxville to Coxen Hole flights
Knoxville to Panama City flights
Norfolk to Guatemala City flights
Myrtle Beach to Panama City flights
Knoxville to Managua flights
Fayetteville to Guatemala City flights
Greensboro to Philip S.W.Goldson flights
Asheville to San Salvador flights

Top 4 airlines flying from Durham to Panama

Discover the top 4 airlines that operate flights from Durham to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$579FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$282Average$413FlexibilityNo cancel feeOn-time70%
DeltaCheapest$297Average$606FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$494FlexibilityNo cancel feeOn-time69%

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