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Panama

$191+ Cheap flights from Durham, NC to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — PTY
Jan 15 — Jan 221
Thu 1/15
Thu 1/22
1 adult, Economy
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Cheap flight deals from Durham to Panama

Cheapest flights from Durham to Panama
Explore the most affordable flight options available from Durham to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 16, 2025.

This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:10 amRDU - PTY
1 stop10h 57mUnited Airlines
Wed 1/2110:00 amPTY - RDU
1 stop11h 05mUnited Airlines
Deal found 12/14$509
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/308:17 pmRDU - PTY
2 stops19h 37mAmerican Airlines
Wed 1/212:27 pmPTY - RDU
2 stops19h 28mAmerican Airlines
Deal found 12/14$513
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/298:17 pmRDU - PTY
2 stops19h 37mAmerican Airlines
Mon 1/194:50 pmPTY - RDU
2 stops19h 31mAmerican Airlines
Deal found 12/14$543
This United Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/296:10 amRDU - PTY
1 stop13h 28mUnited Airlines
Mon 1/194:41 pmPTY - RDU
1 stop29h 49mUnited Airlines
Deal found 12/14$558
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:31 amRDU - PTY
2 stops13h 07mUnited Airlines
Wed 12/314:41 pmPTY - RDU
1 stop18h 40mUnited Airlines
Deal found 12/16$626
This Copa Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/293:11 pmRDU - PTY
Nonstop4h 35mCopa Airlines
Mon 1/198:57 amPTY - RDU
Nonstop4h 18mCopa Airlines
Deal found 12/14$634
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:16 pmRDU - PTY
2 stops21h 37mAmerican Airlines
Wed 12/314:55 pmPTY - RDU
1 stop7h 38mAmerican Airlines
Deal found 12/15$675
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:48 pmRDU - PTY
2 stops17h 05mAmerican Airlines
Fri 1/162:27 pmPTY - RDU
2 stops18h 54mAmerican Airlines
Deal found 12/16$760

Find flight deals from Durham to Panama

Keep the following information in mind while searching for Durham to Panama flight deals. Data was last updated December 16, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$441
(Copa Airlines)

One-way from

$191
(Kiwi.com)

Popular in

December

Cheapest in

October

Average price

$809
Provider with most accurate pricing for Raleigh-Durham-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-Panama City Tocumen Intl flights.
Search Deals
From Durham to Panama
Search Deals
One-way flight from Durham to Panama
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($28 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Durham to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
Use the filters below to find and compare flights from Durham to Panama that are best for you.

Fly from

Durham

Fly to

Panama

Route

Depart

Return

Price

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 3/13

4:14 pm-7:46 pm

Nonstop4h 32m

Panama City Tocumen Intl

Fri 3/20

8:57 am-2:23 pm

Nonstop4h 26m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Wed 2/4

3:12 pm-7:46 pm

Nonstop4h 34m

Panama City Tocumen Intl

Wed 2/18

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 2/20

3:12 pm-7:46 pm

Nonstop4h 34m

Panama City Tocumen Intl

Mon 2/23

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 1/30

3:09 pm-7:46 pm

Nonstop4h 37m

Panama City Tocumen Intl

Sun 2/8

8:57 am-1:14 pm

Nonstop4h 17m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 1/19

3:09 pm-7:46 pm

Nonstop4h 37m

Panama City Tocumen Intl

Mon 1/26

8:57 am-1:15 pm

Nonstop4h 18m

$441

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 4/20

6:30 am-2:14 pm

1 stop8h 44m

Panama City Tocumen Intl

Mon 5/4

9:45 am-9:48 pm

1 stop11h 03m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Mon 1/26

6:15 am-7:38 pm

1 stop13h 23m

Panama City Tocumen Intl

Thu 1/29

11:35 am-10:38 pm

1 stop11h 03m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Sun 1/25

6:15 am-2:45 pm

1 stop8h 30m

Panama City Tocumen Intl

Wed 2/4

10:00 am-9:05 pm

1 stop11h 05m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 1/23

6:00 am-7:38 pm

1 stop13h 38m

Panama City Tocumen Intl

Fri 1/30

8:55 am-10:30 pm

1 stop13h 35m

$456

RaleighPanama City

RDU - PTY

RDUPTY

Raleigh-Durham

Fri 1/30

11:18 am-8:02 pm

1 stop8h 44m

Panama City Tocumen Intl

Fri 2/6

10:00 am-9:05 pm

1 stop11h 05m

$456

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/15

Showing 1-10 of 20 results
1
2

Best time to book a flight from Durham to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Durham with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Durham to Panama

What is the cheapest month to book a flight from Durham to Panama?

Currently, August is the cheapest month in which you can book a flight from Durham to Panama (average of $234). Flying from Durham to Panama in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DU8 to PA?

Find hourly flight availability from Durham to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 16, 2025.

It’s typically best to fly out from Durham to Panama at noon. Doing so could potentially save you 41% on the flight price compared to flying in the morning, which is usually more expensive.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated December 16, 2025.
Read reviews from past customers who have flown Delta, Copa Airlines, and United Airlines from Durham to Panama. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,008 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Copa Airlines
7.6
Good
1,556 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,092 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,049 reviews
Delta
7.9
Good
8,008 reviews

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.1

Overall

7.9

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Durham to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Durham to Panama flight route?

    The Durham to Panama flight path was viewed by 16 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Durham to Panama?

    Departing from Durham to Panama will take you 4h 32m. There are 1851 mi between Durham and Panama. Generally, flights for this route are nonstop.

  • What are the cheapest flights from Durham to Panama?

    On average you can expect to pay $426 for a flight from Durham to Panama. The cheapest flight overall is $139 while the most popular route, (Raleigh-Durham - Panama City Tocumen Intl) is currently priced at $441.

  • Can I find deals for flights from Durham to Panama that include hotel bookings?

    Yes. In addition to deals on Durham to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Durham to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Durham to Panama.

  • Can I find deals for business class flights from Durham to Panama?

    Yes. Cheapflights offers flight deals from Durham to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Durham to Panama?

    Currently, August is the cheapest month in which you can book a flight from Durham to Panama (average of $234). Flying from Durham to Panama in December is currently the most expensive (average of $474). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Durham to Panama

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Durham to Panama

Discover the top 4 airlines that operate flights from Durham to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$249Average$583FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$352Average$470FlexibilityNo cancel feeOn-time70%
DeltaCheapest$367Average$531FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$409Average$513FlexibilityNo cancel feeOn-time69%

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