Panama

$179+ Cheap flights from the Dominican Republic to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/3. Fares are subject to change and may not be available on all flights or dates of travel.
PUJ — PTY
Dec 26 — Jan 21
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Find flight deals from Dominican Republic to Panama

Cheapest flights from Dominican Republic to Panama
Explore the most affordable flight options available from Dominican Republic to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 26, 2025.

This Copa Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/211:53 pmPUJ - PTY
Nonstop2h 46mCopa Airlines
Wed 1/218:59 amPTY - PUJ
Nonstop2h 37mCopa Airlines
Deal found 11/24$423
This Mytrip deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/15:45 pmSDQ - PTY
1 stop16h 05mAvianca
Wed 12/245:50 pmPTY - SDQ
1 stop16h 35mAvianca
Deal found 11/24$477
This Avianca deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1112:40 pmPUJ - PTY
1 stop13h 20mAvianca
Sat 12/132:55 amPTY - PUJ
1 stop7h 35mAvianca
Deal found 11/25$477
This Priceline deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/245:55 pmPUJ - PTY
1 stop15h 55mAvianca
Wed 12/315:50 pmPTY - PUJ
1 stop16h 40mAvianca
Deal found 11/24$501
This Avianca deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/612:20 pmSDQ - PTY
1 stop5h 35mAvianca
Sun 12/72:55 amPTY - SDQ
1 stop12h 55mAvianca
Deal found 11/26$520
This Copa Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2812:48 pmPUJ - PTY
Nonstop2h 45mCopa Airlines
Sun 1/412:25 pmPTY - PUJ
Nonstop2h 38mCopa Airlines
Deal found 11/25$522
This Copa Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:00 amSDQ - PTY
Nonstop2h 37mCopa Airlines
Thu 1/88:10 amPTY - SDQ
Nonstop2h 22mCopa Airlines
Deal found 11/24$525
This Copa Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/102:14 pmSDQ - PTY
Nonstop2h 36mCopa Airlines
Wed 12/317:26 pmPTY - SDQ
Nonstop2h 30mCopa Airlines
Deal found 11/25$536
This Avianca deal was found by Cheapflights users on 11/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/255:45 pmSDQ - PTY
1 stop8h 15mAvianca
Tue 1/62:55 amPTY - SDQ
1 stop12h 55mAvianca
Deal found 11/26$539
This Copa Airlines deal was found by Cheapflights users on 11/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:55 amSDQ - PTY
Nonstop2h 35mCopa Airlines
Thu 12/187:26 pmPTY - SDQ
Nonstop2h 30mCopa Airlines
Deal found 11/25$543
This Copa Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/162:14 pmSDQ - PTY
Nonstop2h 36mCopa Airlines
Thu 1/19:42 amPTY - SDQ
Nonstop2h 27mCopa Airlines
Deal found 11/24$548
This Copa Airlines deal was found by Cheapflights users on 11/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/306:00 amSDQ - PTY
Nonstop2h 37mCopa Airlines
Sun 1/48:10 amPTY - SDQ
Nonstop2h 22mCopa Airlines
Deal found 11/24$555

Cheap flight deals from Dominican Republic to Panama

Keep the following information in mind while searching for Dominican Republic to Panama flight deals. Data was last updated November 26, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$389
(Priceline)

One-way from

$179
(Priceline)

Popular in

January

Cheapest in

November

Average price

$382

Good round-trip deal

$357 or less

Good one-way deal

$268 or less
Provider with most accurate pricing for Punta Cana-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Punta Cana-Panama City Tocumen Intl flights.
From Dominican Republic to Panama
One-way flight from Dominican Republic to Panama
Highest demand for flights based on searches. 2% potential increase in price ($10 potential increase over avg. RT price).
Cheapest flight prices on average. 0% potential price decrease ($2 potential savings vs. average RT price).
Average for round-trip flights in November 2025
Price to beat on a round-trip flight from Dominican Republic to Panama.
Price to beat on a one-way flight from Dominican Republic to Panama.

Cheapflights Fare Finder

 
Customize your flight search to find flights from Dominican Republic to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
Use the filters below to find and compare flights from the Dominican Republic to Panama that are best for you.

Fly from

Dominican Republic

Fly to

Panama

Route

Depart

Return

Price

Punta CanaPanama City

PUJ - PTY

PUJPTY

Punta Cana

Thu 2/19

5:55 pm-8:50 am

1 stop15h 55m

Panama City Tocumen Intl

Mon 2/23

9:45 am-4:45 pm

1 stop6h 00m

$389

Punta CanaPanama City

PUJ - PTY

PUJPTY

Punta Cana

Tue 4/21

11:50 am-4:30 pm

1 stop5h 40m

Panama City Tocumen Intl

Sun 4/26

10:05 pm-10:40 am

1 stop11h 35m

$400

Puerto PlataPanama City

POP - PTY

POPPTY

Puerto Plata La Union

Tue 4/21

12:37 pm-2:19 pm

Nonstop2h 42m

Panama City Tocumen Intl

Sun 4/26

7:55 am-11:32 am

Nonstop2h 37m

$407

Santiago de los CaballerosPanama City

STI - PTY

STIPTY

Santiago de los Caballeros

Sat 1/31

3:51 pm-5:43 pm

Nonstop2h 52m

Panama City Tocumen Intl

Thu 2/5

11:26 am-2:56 pm

Nonstop2h 30m

$407

Punta CanaPanama City

PUJ - PTY

PUJPTY

Punta Cana

Wed 1/7

1:46 pm-3:33 pm

Nonstop2h 47m

Panama City Tocumen Intl

Sun 1/11

7:58 am-11:35 am

Nonstop2h 37m

$423

Punta CanaPanama City

PUJ - PTY

PUJPTY

Punta Cana

Thu 12/11

12:04 pm-1:50 pm

Nonstop2h 46m

Panama City Tocumen Intl

Mon 12/15

7:06 am-10:48 am

Nonstop2h 42m

$423

Punta CanaPanama City

PUJ - PTY

PUJPTY

Punta Cana

Tue 4/21

11:42 am-1:29 pm

Nonstop2h 47m

Panama City Tocumen Intl

Sun 4/26

7:27 am-11:01 am

Nonstop2h 34m

$423

Punta CanaPanama City

PUJ - PTY

PUJPTY

Punta Cana

Wed 12/24

5:56 pm-7:40 pm

Nonstop2h 44m

Panama City Tocumen Intl

Wed 12/31

10:25 am-2:07 pm

Nonstop2h 42m

$423

Santiago de los CaballerosPanama City

STI - PTY

STIPTY

Santiago de los Caballeros

Sat 1/17

3:51 pm-5:43 pm

Nonstop2h 52m

Panama City Tocumen Intl

Thu 1/22

11:26 am-2:56 pm

Nonstop2h 30m

$425

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 2/17

12:20 pm-4:55 pm

1 stop5h 35m

Panama City Tocumen Intl

Mon 2/23

2:55 am-11:25 am

1 stop7h 30m

$477

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/25

Showing 1-10 of 53 results
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Best time to book a flight from Dominican Republic to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Dominican Republic with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from the Dominican Republic to Panama

What is the cheapest month to book a flight from Dominican Republic to Panama?

Currently, April is the cheapest month in which you can book a flight from Dominican Republic to Panama (average of $160). Flying from Dominican Republic to Panama in January is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DO to PA?

Find hourly flight availability from Dominican Republic to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 26, 2025.

A simple way to save on the total cost of your ticket is to fly from Dominican Republic to Panama in the evening. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight at noon.

What is the cheapest day to fly from Dominican Republic to Panama?

Use this chart to determine the cheapest time to fly round-trip from Dominican Republic to Panama. Price data was last updated on December 8, 2024.

Travelers seeking maximum savings on their Dominican Republic to Panama flight should consider departing on Friday at noon when fares are most often at their lowest. Thursday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Dominican Republic to Panama

Explore weekly flight availability from Dominican Republic to Panama. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 26, 2025.

The most flights from DO0 to PA0 are scheduled on a Monday (13 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (6 on average).

How often are flights from the Dominican Republic to Panama delayed?

About 4% of weekly flights between Dominican Republic and Panama have experienced delays in the past year, with the average delay time being 121 minutes.

What is the most punctual flight time for the Dominican Republic to Panama flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Wednesday tends to have the lowest number of delays on this route, whereas Thursday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on the Dominican Republic to Panama flights?

Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 4% of flights being delayed.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 26, 2025.
Read through reviews of airlines operating flights from the Dominican Republic to Panama, such as Copa Airlines and Avianca. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Comfort

7.4

Crew

8.1

Overall

7.6

Food

6.8

Entertainment

6.8

Boarding

7.8

Reviews

1 / 20
10.0
Excellent

Juan Pablo,Sep 2025

MEX - PTY

never better, had a very plesent trip to panama, cant say the same thing of my trip, from panama to santa cruz... it was very poor, unconftrable and boring

Related info for your journey

Find useful and relevant information for your journey from Dominican Republic to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Dominican Republic to Panama flight route?

  • How long is the flight from Dominican Republic to Panama?

    There are many flights that can get you from Dominican Republic to Panama in 2h 42m. Fly via Avianca or Copa Airlines to get the fastest option. The distance from Dominican Republic to Panama is about 944 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • Can I find deals for flights from Dominican Republic to Panama that include hotel bookings?

    Yes. In addition to deals on Dominican Republic to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Dominican Republic to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Dominican Republic to Panama.

  • Can I find deals for business class flights from Dominican Republic to Panama?

    Yes. Cheapflights offers flight deals from Dominican Republic to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Dominican Republic to Panama?

    Currently, April is the cheapest month in which you can book a flight from Dominican Republic to Panama (average of $160). Flying from Dominican Republic to Panama in January is currently the most expensive (average of $389). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Dominican Republic to Panama

Discover the top 2 airlines that operate flights from Dominican Republic to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 26, 2025.
AirlineCheapestAverageFlexibilityOn-time
AviancaCheapest$281Average$375FlexibilityNo cancel feeOn-time71%
Copa AirlinesCheapest$368Average$473FlexibilityNo cancel feeOn-time70%

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