In terms of precipitation, rainfall in Panama ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular airlines that fly from Detroit to Panama?

When booking a flight from Detroit to Panama, you may want to consider flying on American Airlines, Delta or United Airlines as they are the most popular for this route.

What airport do you fly from for flights from Detroit to Panama?

For a flight from Detroit to Panama, you will be flying from All airports. Detroit All airports (DTT) is just 0.6 mi from the center of the city.

Can I find deals for flights from Detroit to Panama that include hotel bookings?

Yes. In addition to deals on Detroit to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to Panama?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama.

Can I find deals for business class flights from Detroit to Panama?

Yes. Cheapflights offers flight deals from Detroit to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$167+ Flights from Detroit to Panama

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Cheap flight deals from Detroit to Panama

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$408 (Avianca Connect)
One-way from	$167 (Kiwi.com)
Popular in	September
Cheapest in	August
Average price	$1,558

Provider with most accurate pricing for Detroit (DTT)-Panama City Tocumen Intl flight deals.

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Provider most trusted by Cheapflights users for Detroit (DTT)-Panama City Tocumen Intl flights.

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From Detroit (DTT) to Panama

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One-way flight from Detroit (DTT) to Panama

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Highest demand for flights based on searches. 14% potential increase in price ($136 potential increase over avg. RT price).

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Cheapest flight prices on average. 8% potential price decrease ($66 potential savings vs. average RT price).

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Average for round-trip flights in September 2025

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Find flight deals from Detroit to Panama

Cheapest flights from Detroit to Panama
Explore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 23, 2025.

lun. 10/276:17 amDTW - PTY

2 stops19h 23mMultiple Airlines

mar. 11/45:55 pmPTY - DTW

2 stops20h 14mMultiple Airlines

Deal found 9/23

$408

lun. 10/206:17 amDTW - PTY

2 stops15h 53mMultiple Airlines

ven. 10/2410:05 pmPTY - DTW

2 stops20h 55mMultiple Airlines

Deal found 9/22

$431

mar. 10/76:43 amDTW - PTY

2 stops15h 27mMultiple Airlines

jeu. 10/93:20 amPTY - DTW

2 stops19h 10mMultiple Airlines

Deal found 9/23

$451

jeu. 12/49:00 amDTW - PTY

2 stops16h 00mMultiple Airlines

dim. 12/72:55 pmPTY - DTW

2 stops23h 14mMultiple Airlines

Deal found 9/20

$462

sam. 10/47:35 pmDTW - PTY

3 stops29h 35mMultiple Airlines

ven. 10/103:25 amPTY - DTW

2 stops19h 05mMultiple Airlines

Deal found 9/22

$470

dim. 10/196:17 amDTW - PTY

1 stop15h 20mMultiple Airlines

sam. 10/2510:25 amPTY - DTW

1 stop8h 35mMultiple Airlines

Deal found 9/23

$472

ven. 10/246:17 amDTW - PTY

1 stop11h 08mMultiple Airlines

sam. 10/2510:25 amPTY - DTW

1 stop8h 35mMultiple Airlines

Deal found 9/22

$475

Best flights from Detroit to Panama
Discover carefully curated flight deals from Detroit to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated septembre 23, 2025.

lun. 10/276:17 amDTW - PTY

2 stops19h 23mMultiple Airlines

mar. 11/45:55 pmPTY - DTW

2 stops20h 14mMultiple Airlines

Deal found 9/23

$408

jeu. 12/49:00 amDTW - PTY

2 stops16h 00mMultiple Airlines

dim. 12/72:55 pmPTY - DTW

2 stops23h 14mMultiple Airlines

Deal found 9/20

$462

lun. 1/266:11 amDTW - PTY

2 stops18h 29mMultiple Airlines

jeu. 2/265:55 pmPTY - DTW

2 stops20h 14mMultiple Airlines

Deal found 9/23

$475

mer. 11/56:11 amDTW - PTY

1 stop14h 08mMultiple Airlines

mer. 11/1212:03 pmPTY - DTW

1 stop12h 22mMultiple Airlines

Deal found 9/21

$479

sam. 10/46:41 amDTW - PTY

2 stops15h 29mMultiple Airlines

ven. 10/103:25 amPTY - DTW

2 stops19h 05mMultiple Airlines

Deal found 9/21

$497

ven. 1/236:50 amDTW - PTY

2 stops17h 50mMultiple Airlines

dim. 1/252:55 pmPTY - DTW

2 stops23h 14mMultiple Airlines

Deal found 9/22

$553

mar. 10/77:22 amDTW - PTY

3 stops14h 48mMultiple Airlines

ven. 10/1010:05 pmPTY - DTW

3 stops33h 33mMultiple Airlines

Deal found 9/23

$581

jeu. 1/157:58 amDTW - PTY

2 stops17h 02mMultiple Airlines

lun. 1/192:55 amPTY - DTW

2 stops18h 28mMultiple Airlines

Deal found 9/23

$596

Last-minute flights from Detroit to Panama
Discover last-minute flight deals from Detroit to Panama. Data last updated septembre 23, 2025 and is based on user searches.

sam. 10/47:35 pmDTW - PTY

3 stops29h 35mMultiple Airlines

ven. 10/103:25 amPTY - DTW

2 stops19h 05mMultiple Airlines

Deal found 9/22

$470

mar. 10/76:43 amDTW - PTY

2 stops15h 27mMultiple Airlines

jeu. 10/93:20 amPTY - DTW

2 stops19h 10mMultiple Airlines

Deal found 9/23

$451

lun. 10/136:43 amDTW - PTY

1 stop14h 36mMultiple Airlines

ven. 10/1712:03 pmPTY - DTW

1 stop10h 27mMultiple Airlines

Deal found 9/20

$479

dim. 10/196:17 amDTW - PTY

1 stop15h 20mMultiple Airlines

sam. 10/2510:25 amPTY - DTW

1 stop8h 35mMultiple Airlines

Deal found 9/23

$472

lun. 10/206:17 amDTW - PTY

2 stops15h 53mMultiple Airlines

ven. 10/2410:05 pmPTY - DTW

2 stops20h 55mMultiple Airlines

Deal found 9/22

$431

ven. 10/246:17 amDTW - PTY

1 stop11h 08mMultiple Airlines

sam. 10/2510:25 amPTY - DTW

1 stop8h 35mMultiple Airlines

Deal found 9/22

$475

lun. 10/276:17 amDTW - PTY

2 stops19h 23mMultiple Airlines

mar. 11/45:55 pmPTY - DTW

2 stops20h 14mMultiple Airlines

Deal found 9/23

$408

One-way flights from Detroit to Panama
Search for one-way flight options from Detroit to Panama. Find affordable one-way fares based on user searches. Data last updated septembre 23, 2025.

mer. 11/57:00 amDTW - PTY

2 stops25h 50mMultiple Airlines

Deal found 9/21

$167

lun. 10/276:17 amDTW - PTY

2 stops19h 23mMultiple Airlines

Deal found 9/23

$173

mar. 10/217:22 amDTW - PTY

3 stops38h 48mMultiple Airlines

Deal found 9/21

$183

sam. 10/1810:25 pmDTW - PTY

2 stops23h 45mMultiple Airlines

Deal found 9/22

$194

dim. 10/196:17 amDTW - PTY

3 stops31h 18mMultiple Airlines

Deal found 9/22

$195

lun. 10/206:17 amDTW - PTY

1 stop26h 54mMultiple Airlines

Deal found 9/22

$262

Fly from

Fly to

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

lun. 10/27

6:17 am-12:40 am

2 stops19h 23m

Panama City Tocumen Intl

mar. 11/4

5:55 pm-2:09 pm

2 stops20h 14m

$408

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

jeu. 12/4

9:00 am-1:00 am

2 stops16h 00m

Panama City Tocumen Intl

dim. 12/7

2:55 pm-2:09 pm

2 stops23h 14m

$462

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

lun. 1/26

6:11 am-12:40 am

2 stops18h 29m

Panama City Tocumen Intl

jeu. 2/26

5:55 pm-2:09 pm

2 stops20h 14m

$475

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

mer. 11/5

6:11 am-8:19 pm

1 stop14h 08m

Panama City Tocumen Intl

mer. 11/12

12:03 pm-12:25 am

1 stop12h 22m

$479

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

sam. 10/4

6:41 am-9:10 pm

2 stops15h 29m

Panama City Tocumen Intl

ven. 10/10

3:25 am-11:30 pm

2 stops19h 05m

$497

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

ven. 1/23

6:50 am-12:40 am

2 stops17h 50m

Panama City Tocumen Intl

dim. 1/25

2:55 pm-2:09 pm

2 stops23h 14m

$553

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

mar. 10/7

7:22 am-9:10 pm

3 stops14h 48m

Panama City Tocumen Intl

ven. 10/10

10:05 pm-8:38 am

3 stops33h 33m

$581

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

jeu. 1/15

7:58 am-1:00 am

2 stops17h 02m

Panama City Tocumen Intl

lun. 1/19

2:55 am-9:23 pm

2 stops18h 28m

$596

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

mer. 11/5

7:00 am-8:50 am

2 stops25h 50m

$167

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

lun. 10/27

6:17 am-12:40 am

2 stops19h 23m

$173

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/21

Showing 1-10 of 14 results

Best time to book a flight from Detroit to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama

What is the cheapest month to book a flight from Detroit to Panama?

Currently, October is the cheapest month in which you can book a flight from Detroit to Panama (average of $478). Flying from Detroit to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to PA?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to Panama as you normally would.

Reviews of airlines servicing Panama

See what other customers who have flown with Delta, United Airlines, and American Airlines from Detroit to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,973 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,928 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,973 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly from for flights from Detroit to Panama?
For a flight from Detroit to Panama, you will be flying from All airports. Detroit All airports (DTT) is just 0.6 mi from the center of the city.
Can I find deals for flights from Detroit to Panama that include hotel bookings?
Yes. In addition to deals on Detroit to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to Panama?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama.
Can I find deals for business class flights from Detroit to Panama?
Yes. Cheapflights offers flight deals from Detroit to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit to Panama?
Currently, October is the cheapest month in which you can book a flight from Detroit to Panama (average of $478). Flying from Detroit to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Detroit to Panama

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$578	Average$781	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$608	Average$851	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$608	Average$927	FlexibilityNo cancel fee	On-timeN/A

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$167+ Cheap flights from Detroit (DTT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/5. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Detroit to Panama

Keep the following information in mind while searching for Detroit to Panama flight deals. Data was last updated septembre 23, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Detroit to Panama

Cheapest flights from Detroit to PanamaExplore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 23, 2025.

Explore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 23, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit to Panama that are best for you.

Best time to book a flight from Detroit to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Detroit with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama

What is the cheapest month to book a flight from Detroit to Panama?

What is the cheapest time of day to fly from DTT to PA?

Find hourly flight availability from Detroit to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septembre 23, 2025.

Reviews of airlines servicing Panama

See what other customers who have flown with Delta, United Airlines, and American Airlines from Detroit to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Detroit to Panama?

Can I find deals for flights from Detroit to Panama that include hotel bookings?

How can I find direct flights from Detroit to Panama?

Can I find deals for business class flights from Detroit to Panama?

What is the cheapest month to book a flight from Detroit to Panama?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Panama

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Detroit to Panama

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Book with Flexibility

Travel Smart

Cheapest flights from Detroit to Panama
Explore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septembre 23, 2025.