HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama

$185+ Cheap flights from Detroit (DTT) to Panama

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
DTT — PTY
Aug 12 — Aug 191
Tue 8/12
Tue 8/19
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Detroit to Panama with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Detroit to Panama

Keep the following information in mind while searching for Detroit to Panama flight deals. Data was last updated August 7, 2025.

Round-trip from

$402
(Avianca Connect)

One-way from

$185
(Kiwi.com)

Popular in

September

Cheapest in

August

Average price

$637
From Detroit (DTT) to Panama
Search Deals
One-way flight from Detroit (DTT) to Panama
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($92 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($53 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from Detroit to Panama

Cheapest flights from Detroit to Panama
Explore the most affordable flight options available from Detroit to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2025.

This Avianca Connect deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:30 amDTW - PTY
2 stops15h 40mMultiple Airlines
Sun 9/2810:05 pmPTY - DTW
2 stops21h 09mMultiple Airlines
Deal found 8/5$402
This Avianca Connect deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:30 amDTW - PTY
2 stops15h 40mMultiple Airlines
Sat 9/2710:05 pmPTY - DTW
2 stops21h 09mMultiple Airlines
Deal found 8/5$427
This Avianca Connect deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:00 amDTW - PTY
2 stops18h 00mMultiple Airlines
Mon 11/172:55 pmPTY - DTW
2 stops23h 14mMultiple Airlines
Deal found 8/6$435
This Avianca Connect deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/46:30 amDTW - PTY
2 stops18h 40mMultiple Airlines
Wed 9/103:20 amPTY - DTW
2 stops15h 54mMultiple Airlines
Deal found 8/5$436
This Avianca Connect deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/196:41 amDTW - PTY
2 stops19h 04mMultiple Airlines
Thu 9/253:20 amPTY - DTW
2 stops19h 23mMultiple Airlines
Deal found 8/5$441
This Avianca Connect deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:28 amDTW - PTY
2 stops18h 42mMultiple Airlines
Wed 2/43:19 amPTY - DTW
2 stops18h 04mMultiple Airlines
Deal found 8/5$451

Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2025.
Use the filters below to find and compare flights from Detroit to Panama that are best for you.

Fly from

Detroit

Fly to

Panama

Route

Depart

Return

Price

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/25

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sun 9/28

10:05 pm-8:14 pm

2 stops21h 09m

$402

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 9/20

6:30 am-9:10 pm

2 stops15h 40m

Panama City Tocumen Intl

Sat 9/27

10:05 pm-8:14 pm

2 stops21h 09m

$427

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 11/13

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Mon 11/17

2:55 pm-2:09 pm

2 stops23h 14m

$435

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Thu 9/4

6:30 am-12:10 am

2 stops18h 40m

Panama City Tocumen Intl

Wed 9/10

3:20 am-8:14 pm

2 stops15h 54m

$436

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Fri 9/19

6:41 am-12:45 am

2 stops19h 04m

Panama City Tocumen Intl

Thu 9/25

3:20 am-11:43 pm

2 stops19h 23m

$441

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Tue 8/19

6:28 am-12:10 am

2 stops18h 42m

Panama City Tocumen Intl

Wed 2/4

3:19 am-9:23 pm

2 stops18h 04m

$451

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Mon 9/1

6:15 am-12:45 am

2 stops19h 30m

$185

DetroitPanama City

DTW - PTY

DTWPTY

Detroit Metropolitan Wayne County

Sat 8/16

6:15 am-9:10 pm

2 stops15h 55m

$215

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/5

Best time to book a flight from Detroit to Panama

Have a flexible travel schedule? Discover the best time to fly to Panama from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit to Panama

What is the cheapest month to book a flight from Detroit to Panama?

Currently, October is the cheapest month in which you can book a flight from Detroit to Panama (average of $478). Flying from Detroit to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTT to PA?

Find hourly flight availability from Detroit to Panama. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 7, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Detroit to Panama as you normally would.

Reviews of airlines servicing Panama

Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated August 7, 2025.
See what other customers who have flown with American Airlines from Detroit to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Crew

8.0

Comfort

7.2

Food

6.5

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.
American Airlines
7.2
Good
10,000 reviews
American Airlines
7.2
Good
10,000 reviews

Entertainment

6.9

Boarding

7.5

Crew

8.0

Comfort

7.2

Food

6.5

Overall

7.2

Reviews

1 / 20
10.0
Excellent

Leonardo,May 2025

JFK - BGI

Good airline and so far i give them 8 out of 10.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Detroit to Panama?

    For a flight from Detroit to Panama, you will be flying from All airports. Detroit All airports (DTT) is just 0.6 mi from the center of the city.

  • Can I find deals for flights from Detroit to Panama that include hotel bookings?

    Yes. In addition to deals on Detroit to Panama flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Panama?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Panama.

  • Can I find deals for business class flights from Detroit to Panama?

    Yes. Cheapflights offers flight deals from Detroit to Panama by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit to Panama?

    Currently, October is the cheapest month in which you can book a flight from Detroit to Panama (average of $478). Flying from Detroit to Panama in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Detroit to Panama

See prices for flight routes from nearby airports that may be better suited for you.
O'Hare Intl to San José flights
O'Hare Intl to Panama City flights
O'Hare Intl to Liberia flights
O'Hare Intl to Guatemala City flights
Midway to San José flights
O'Hare Intl to Philip S.W.Goldson flights
Detroit to San José flights
Midway to Liberia flights
O'Hare Intl to San Salvador flights
Midway to Guatemala City flights
O'Hare Intl to Managua flights
O'Hare Intl to Coxen Hole flights
Grand Rapids to San José flights
Detroit to Liberia flights
Detroit to Panama City flights
Midway to Philip S.W.Goldson flights
Midway to Panama City flights
Grand Rapids to Liberia flights
O'Hare Intl to San Pedro Sula flights
Detroit to Guatemala City flights
Detroit to Philip S.W.Goldson flights
Midway to San Salvador flights
Grand Rapids to Philip S.W.Goldson flights
Detroit to San Salvador flights
Midway to San Pedro Sula flights
Detroit to San Pedro Sula flights
O'Hare Intl to David flights
Grand Rapids to Coxen Hole flights
Grand Rapids to Guatemala City flights
South Bend to San Salvador flights
Detroit to Coxen Hole flights
Lansing to San José flights
Midway to Coxen Hole flights
Grand Rapids to San Salvador flights
South Bend to Panama City flights
Detroit to Managua flights
Flint to San José flights
Lansing to Panama City flights
Bay City to San José flights
Flint to Philip S.W.Goldson flights
Flint to Liberia flights
Kalamazoo to Panama City flights
Kalamazoo to San José flights
Grand Rapids to Managua flights
South Bend to Liberia flights
Midway to Tegucigalpa flights
Flint to Panama City flights

Top 3 airlines flying from Detroit to Panama

Discover the top 3 airlines that operate flights from Detroit to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$578Average$800FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$608Average$851FlexibilityNo cancel feeOn-time69%
DeltaCheapest$608Average$896FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.